𝕏

Task 55905159

Name HuVeMOp_20240630080046859196_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_738_2
Workunit 26307943
Created 3 Jul 2024, 10:35:44 UTC
Sent 3 Jul 2024, 13:33:36 UTC
Report deadline 6 Jul 2024, 16:26:24 UTC
Received 5 Jul 2024, 22:45:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224115
Run time 1 hours 27 min 12 sec
CPU time 1 hours 13 min 54 sec
Validate state Valid
Credit 51.48
Device peak FLOPS 4.81 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.86 MB
Peak swap size 391.75 GB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_738_2_r391011214_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_738_2_r391011214_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.000089
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 27710935, states[0] = -94.578227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55283758, states[0] = -94.764876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84648630, states[0] = -64.931719, states[40]= 0.000008
Saving checkpoint... 
Iteration: 108937154, states[0] = -94.901795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137173322, states[0] = -93.944546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164156917, states[0] = -76.628030, states[40]= 0.000001
Saving checkpoint... 
Iteration: 192457165, states[0] = -94.907673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224224902, states[0] = -94.608157, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_738_2_r391011214_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_738_2_r391011214_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.000089
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 224224902
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.608157 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 251942251, states[0] = -94.902447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281713024, states[0] = -94.563601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314087098, states[0] = -1.597279, states[40]= 0.004014
Saving checkpoint... 
Iteration: 344644132, states[0] = -59.467505, states[40]= 0.000019
Saving checkpoint... 
Iteration: 374492351, states[0] = -94.915752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405001919, states[0] = 43.298090, states[40]= 0.483306
Saving checkpoint... 
Iteration: 433703647, states[0] = -94.524314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466042711, states[0] = 19.791216, states[40]= 0.001661
Saving checkpoint... 
Iteration: 498235053, states[0] = -94.640653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511175491, states[0] = -94.169820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517956981, states[0] = -94.906064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525187160, states[0] = -94.444397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532192133, states[0] = -94.471690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538429323, states[0] = -94.896201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545759588, states[0] = -94.708280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552706282, states[0] = -94.534907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560169497, states[0] = -92.934698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567777935, states[0] = -94.748156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575328889, states[0] = -94.825050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582548424, states[0] = 17.654870, states[40]= 0.002027
Saving checkpoint... 
Iteration: 590589945, states[0] = -3.787150, states[40]= 0.003735
Saving checkpoint... 
Iteration: 598296170, states[0] = -94.780506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605677138, states[0] = -94.268628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612804865, states[0] = -94.793806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618904412, states[0] = -94.884332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626167171, states[0] = -91.574548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632730449, states[0] = -94.625140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640695618, states[0] = -94.487748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648122266, states[0] = -35.826085, states[40]= 0.000538
Saving checkpoint... 
Iteration: 655188978, states[0] = -94.454635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662783139, states[0] = -94.757655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670370953, states[0] = -94.863280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677832525, states[0] = -94.828624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685159528, states[0] = -81.030429, states[40]= 0.000001
Saving checkpoint... 
Iteration: 692155644, states[0] = -74.566200, states[40]= 0.000002
Saving checkpoint... 
Iteration: 698922784, states[0] = -94.892715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705770673, states[0] = -94.732649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713163318, states[0] = -87.265949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716772528, states[0] = -94.736508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720249667, states[0] = -94.682213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725472027, states[0] = -94.909356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729019520, states[0] = 26.417230, states[40]= 0.002664
Saving checkpoint... 
Iteration: 736924729, states[0] = -94.893374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743672377, states[0] = -93.781452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749447198, states[0] = -94.901849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756040355, states[0] = 20.641969, states[40]= 0.001530
Saving checkpoint... 
Iteration: 763133332, states[0] = -47.474558, states[40]= 0.000122
Saving checkpoint... 
Iteration: 770176053, states[0] = -94.207714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777723733, states[0] = -94.601410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785195764, states[0] = -94.487739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791842074, states[0] = -94.838026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799374929, states[0] = -94.865542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806199489, states[0] = -94.504454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812325144, states[0] = -94.819610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819306586, states[0] = -94.795344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851146389, states[0] = -62.102213, states[40]= 0.000013
Saving checkpoint... 
Iteration: 880886655, states[0] = -94.872955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911652403, states[0] = -69.777744, states[40]= 0.000004
Saving checkpoint... 
Iteration: 943407717, states[0] = -94.884525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964671761, states[0] = -93.651797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971308978, states[0] = -94.798036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978752718, states[0] = -94.689066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985508929, states[0] = 26.698917, states[40]= 0.071444
Saving checkpoint... 
Iteration: 992701516, states[0] = -94.512479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999330369, states[0] = -94.824746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007286759, states[0] = -94.762638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013765749, states[0] = -94.720432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020985412, states[0] = -94.911245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028325880, states[0] = -94.819472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035470293, states[0] = -94.907464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042847047, states[0] = -94.841654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050139941, states[0] = -54.728351, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1057317693, states[0] = -94.809312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064407563, states[0] = -94.883887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071451567, states[0] = -94.901800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077686676, states[0] = -94.438600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083661587, states[0] = -84.540239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090958176, states[0] = -94.903773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096463869, states[0] = -94.905415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103037264, states[0] = 21.724395, states[40]= 0.001376
Saving checkpoint... 
Iteration: 1110711734, states[0] = -94.554576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118632217, states[0] = -46.267247, states[40]= 0.000145
Saving checkpoint... 
Iteration: 1125085032, states[0] = -0.128051, states[40]= 0.004129
Saving checkpoint... 
Iteration: 1132507337, states[0] = 27.011578, states[40]= 0.122426
Saving checkpoint... 
Iteration: 1140846657, states[0] = -94.840832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149122660, states[0] = -36.227428, states[40]= 0.000516
Saving checkpoint... 
Iteration: 1154744540, states[0] = -94.666002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162574705, states[0] = 6.072066, states[40]= 0.003979
Saving checkpoint... 
Iteration: 1169660439, states[0] = -82.593932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176216463, states[0] = -94.572740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183569749, states[0] = 8.588780, states[40]= 0.003675
Saving checkpoint... 
Iteration: 1190725082, states[0] = -94.604230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198472647, states[0] = -94.907327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206192143, states[0] = -94.468553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214724123, states[0] = -94.600740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222032275, states[0] = 23.363236, states[40]= 0.001180
Saving checkpoint... 
Iteration: 1229300717, states[0] = -94.784714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237382112, states[0] = -94.868393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245672324, states[0] = -93.767831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252041594, states[0] = 20.198055, states[40]= 0.001598
Saving checkpoint... 
Iteration: 1260008386, states[0] = 26.752661, states[40]= 0.085852
Saving checkpoint... 
Iteration: 1268640560, states[0] = -55.416839, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1275234878, states[0] = -94.636455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282887740, states[0] = -94.871765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288143755, states[0] = -59.026813, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1295764129, states[0] = -94.715438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302169446, states[0] = -92.905731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309083574, states[0] = 0.852601, states[40]= 0.004172
Saving checkpoint... 
Iteration: 1315999502, states[0] = -94.912839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323233259, states[0] = -94.631070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331279256, states[0] = -94.747171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338325519, states[0] = -94.817607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346098947, states[0] = -12.061389, states[40]= 0.002123
Saving checkpoint... 
Iteration: 1353369029, states[0] = -94.858684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360614354, states[0] = -27.787591, states[40]= 0.000984
Saving checkpoint... 
Iteration: 1368060416, states[0] = 12.823968, states[40]= 0.002954
Saving checkpoint... 
Iteration: 1376186848, states[0] = -94.438325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390511758, states[0] = 26.744532, states[40]= 0.027562
Saving checkpoint... 
Iteration: 1420530875, states[0] = 23.792147, states[40]= 0.001142
Saving checkpoint... 
Iteration: 1454565293, states[0] = 10.680281, states[40]= 0.003344
Saving checkpoint... 
Iteration: 1483213002, states[0] = -94.557856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513740761, states[0] = -95.179804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543182560, states[0] = -93.979427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1574552996, states[0] = -94.683576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602465704, states[0] = -94.579661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631826175, states[0] = -94.496476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661938466, states[0] = -94.479870, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.347163
 - CaMKt in component CaMK (millimolar): 0.001169
 - cass in component intracellular_ions (millimolar): 0.000089
 - nai in component intracellular_ions (millimolar): 6.398245
 - nass in component intracellular_ions (millimolar): 6.398335
 - ki in component intracellular_ions (millimolar): 145.485752
 - kss in component intracellular_ions (millimolar): 145.485741
 - cansr in component intracellular_ions (millimolar): 1.598384
 - cajsr in component intracellular_ions (millimolar): 1.598394
 - cai in component intracellular_ions (millimolar): 0.000092
 - m in component INa (dimensionless): 0.003827
 - hf in component INa (dimensionless): 0.870036
 - hs in component INa (dimensionless): 0.870037
 - j in component INa (dimensionless): 0.870038
 - hsp in component INa (dimensionless): 0.707351
 - jp in component INa (dimensionless): 0.870038
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.714301
 - hLp in component INaL (dimensionless): 0.522017
 - a in component Ito (dimensionless): 0.000647
 - iF in component Ito (dimensionless): 0.999856
 - iS in component Ito (dimensionless): 0.997795
 - ap in component Ito (dimensionless): 0.000330
 - iFp in component Ito (dimensionless): 0.999856
 - iSp in component Ito (dimensionless): 0.999273
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998930
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003240
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001699
 - xs1 in component IKs (dimensionless): 0.022026
 - xs2 in component IKs (dimensionless): 0.000093
 - xk1 in component IK1 (dimensionless): 0.997479
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:08:45 (872): called boinc_finish(0)

</stderr_txt>
]]>