𝕏

Task 55904131

Name HuVeMOp_20240703120444316973_ORdGradInc_k_26-Schmidt_500-conf_282_0
Workunit 26548042
Created 3 Jul 2024, 10:11:03 UTC
Sent 3 Jul 2024, 13:26:46 UTC
Report deadline 6 Jul 2024, 13:26:46 UTC
Received 3 Jul 2024, 22:46:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 47 min 36 sec
CPU time 1 hours 40 min 20 sec
Validate state Valid
Credit 45.30
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.82 MB
Peak swap size 4.13 GB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Schmidt_500-conf_282.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Schmidt_500-conf_282_0_r1496237109_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Schmidt_500-conf_282_0_r1496237109_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.562231
     * GNaL_b in INaL: 0.005530
     * Gto_b in Ito: 0.082039
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031831
     * GKs_b in IKs: 0.001884
     * GK1_b in IK1: 0.165122
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 71.112616
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032960
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11983576, states[0] = -84.811265, states[40]= 0.000001
Saving checkpoint... 
Iteration: 23715631, states[0] = -84.705767, states[40]= 0.000001
Saving checkpoint... 
Iteration: 36348406, states[0] = -25.940073, states[40]= 0.000227
Saving checkpoint... 
Iteration: 48503545, states[0] = 32.659335, states[40]= 0.646578
Saving checkpoint... 
Iteration: 60781538, states[0] = 26.544938, states[40]= 0.000031
Saving checkpoint... 
Iteration: 72722223, states[0] = -84.771232, states[40]= 0.000001
Saving checkpoint... 
Iteration: 85153308, states[0] = -84.002245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97965030, states[0] = -84.739535, states[40]= 0.000001
Saving checkpoint... 
Iteration: 110787990, states[0] = 23.343308, states[40]= 0.000006
Saving checkpoint... 
Iteration: 122000034, states[0] = -80.682692, states[40]= 0.000001
Saving checkpoint... 
Iteration: 134734142, states[0] = -84.832254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 146330749, states[0] = -5.605896, states[40]= 0.000268
Saving checkpoint... 
Iteration: 158459670, states[0] = -84.711046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 171368718, states[0] = -51.195254, states[40]= 0.000034
Saving checkpoint... 
Iteration: 182718835, states[0] = -84.761015, states[40]= 0.000001
Saving checkpoint... 
Iteration: 194266825, states[0] = 31.337034, states[40]= 0.005605
Saving checkpoint... 
Iteration: 205720613, states[0] = -84.769367, states[40]= 0.000001
Saving checkpoint... 
Iteration: 218328566, states[0] = -3.366457, states[40]= 0.000252
Saving checkpoint... 
Iteration: 230124978, states[0] = -58.838428, states[40]= 0.000014
Saving checkpoint... 
Iteration: 241044808, states[0] = 19.755532, states[40]= 0.000008
Saving checkpoint... 
Iteration: 252699455, states[0] = -84.643347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 264239662, states[0] = -84.850733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 276067350, states[0] = 5.916961, states[40]= 0.000109
Saving checkpoint... 
Iteration: 287745359, states[0] = -84.870641, states[40]= 0.000001
Saving checkpoint... 
Iteration: 299560764, states[0] = 10.369795, states[40]= 0.000055
Saving checkpoint... 
Iteration: 311448202, states[0] = -84.632621, states[40]= 0.000001
Saving checkpoint... 
Iteration: 322745893, states[0] = -84.871265, states[40]= 0.000001
Saving checkpoint... 
Iteration: 334467376, states[0] = -84.748257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 347027489, states[0] = 28.208307, states[40]= 0.000124
Saving checkpoint... 
Iteration: 358601666, states[0] = -31.138119, states[40]= 0.000175
Saving checkpoint... 
Iteration: 371273947, states[0] = 29.565475, states[40]= 0.000437
Saving checkpoint... 
Iteration: 383314780, states[0] = 7.712319, states[40]= 0.000084
Saving checkpoint... 
Iteration: 394802775, states[0] = 15.270359, states[40]= 0.000022
Saving checkpoint... 
Iteration: 406843168, states[0] = -20.794733, states[40]= 0.000182
Saving checkpoint... 
Iteration: 419068452, states[0] = 5.124514, states[40]= 0.000121
Saving checkpoint... 
Iteration: 432402644, states[0] = -83.962243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445095845, states[0] = -24.104692, states[40]= 0.000183
Saving checkpoint... 
Iteration: 458404476, states[0] = -84.075786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470797016, states[0] = 18.550146, states[40]= 0.000010
Saving checkpoint... 
Iteration: 482787779, states[0] = 23.434186, states[40]= 0.000006
Saving checkpoint... 
Iteration: 495482398, states[0] = -84.813479, states[40]= 0.000001
Saving checkpoint... 
Iteration: 508360959, states[0] = -42.060238, states[40]= 0.000087
Saving checkpoint... 
Iteration: 520758922, states[0] = 30.454323, states[40]= 0.097580
Saving checkpoint... 
Iteration: 532845203, states[0] = -23.311283, states[40]= 0.000182
Saving checkpoint... 
Iteration: 545968869, states[0] = -84.748500, states[40]= 0.000001
Saving checkpoint... 
Iteration: 558146880, states[0] = -83.019865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570185544, states[0] = -84.526891, states[40]= 0.000001
Saving checkpoint... 
Iteration: 582167721, states[0] = -84.356629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593010096, states[0] = 30.807645, states[40]= 0.063853
Saving checkpoint... 
Iteration: 605412219, states[0] = -84.283983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617708304, states[0] = -84.687073, states[40]= 0.000001
Saving checkpoint... 
Iteration: 630743696, states[0] = -84.852644, states[40]= 0.000001
Saving checkpoint... 
Iteration: 643590551, states[0] = -17.490321, states[40]= 0.000195
Saving checkpoint... 
Iteration: 656453097, states[0] = -84.653151, states[40]= 0.000001
Saving checkpoint... 
Iteration: 669597455, states[0] = -26.057929, states[40]= 0.000185
Saving checkpoint... 
Iteration: 681401365, states[0] = -83.837437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693580050, states[0] = -4.863686, states[40]= 0.000263
Saving checkpoint... 
Iteration: 706348571, states[0] = -27.407760, states[40]= 0.000185
Saving checkpoint... 
Iteration: 718162070, states[0] = -84.277460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730226675, states[0] = -84.779940, states[40]= 0.000001
Saving checkpoint... 
Iteration: 742318254, states[0] = 5.275782, states[40]= 0.000118
Saving checkpoint... 
Iteration: 754263802, states[0] = 31.446276, states[40]= 0.016687
Saving checkpoint... 
Iteration: 766620789, states[0] = -53.651052, states[40]= 0.000026
Saving checkpoint... 
Iteration: 777681370, states[0] = -84.483692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790729266, states[0] = -84.789471, states[40]= 0.000001
Saving checkpoint... 
Iteration: 803561167, states[0] = 10.118826, states[40]= 0.000057
Saving checkpoint... 
Iteration: 816641702, states[0] = -80.228467, states[40]= 0.000001
Saving checkpoint... 
Iteration: 829433660, states[0] = -84.501669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842417166, states[0] = -84.340747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854337060, states[0] = -13.061502, states[40]= 0.000231
Saving checkpoint... 
Iteration: 868508262, states[0] = 30.252713, states[40]= 0.123707
Saving checkpoint... 
Iteration: 881655244, states[0] = -84.094979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893860060, states[0] = -40.988290, states[40]= 0.000096
Saving checkpoint... 
Iteration: 906931998, states[0] = -84.484525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919212216, states[0] = -84.699182, states[40]= 0.000001
Saving checkpoint... 
Iteration: 931008846, states[0] = 30.433511, states[40]= 0.100248
Saving checkpoint... 
Iteration: 942854552, states[0] = -34.528469, states[40]= 0.000152
Saving checkpoint... 
Iteration: 953710312, states[0] = -84.686976, states[40]= 0.000001
Saving checkpoint... 
Iteration: 965289208, states[0] = 22.715745, states[40]= 0.000005
Saving checkpoint... 
Iteration: 977117231, states[0] = -49.394184, states[40]= 0.000041
Saving checkpoint... 
Iteration: 988978378, states[0] = -84.778480, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1001040277, states[0] = 22.166087, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1013431667, states[0] = -84.477779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025743368, states[0] = -84.837498, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1037016038, states[0] = 31.421740, states[40]= 0.007438
Saving checkpoint... 
Iteration: 1048057740, states[0] = 12.290450, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1059695988, states[0] = -84.590107, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1069884481, states[0] = -71.590251, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1080276755, states[0] = 28.516864, states[40]= 0.000161
Saving checkpoint... 
Iteration: 1090038147, states[0] = 23.257223, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1099475562, states[0] = -84.761664, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1109637207, states[0] = -75.306878, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1120736404, states[0] = -84.807750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1131494517, states[0] = -84.837859, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1141860399, states[0] = -41.370590, states[40]= 0.000092
Saving checkpoint... 
Iteration: 1153074442, states[0] = 0.443938, states[40]= 0.000199
Saving checkpoint... 
Iteration: 1163641377, states[0] = -79.918364, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1175053779, states[0] = 14.690870, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1186005204, states[0] = 30.203456, states[40]= 0.366816
Saving checkpoint... 
Iteration: 1195889239, states[0] = -77.775299, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1206678459, states[0] = -84.442009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217198007, states[0] = -84.598766, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1227153509, states[0] = -83.988792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238817016, states[0] = 6.174822, states[40]= 0.000105
Saving checkpoint... 
Iteration: 1249708152, states[0] = -84.663570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1261172302, states[0] = -84.380798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272557562, states[0] = 12.404288, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1283321976, states[0] = 2.470395, states[40]= 0.000164
Saving checkpoint... 
Iteration: 1293703220, states[0] = -84.631130, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1304900840, states[0] = -83.750521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315471591, states[0] = -84.734867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1326411111, states[0] = -84.238858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336658182, states[0] = -84.176327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346333818, states[0] = -9.060184, states[40]= 0.000263
Saving checkpoint... 
Iteration: 1356658813, states[0] = -84.191158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366742062, states[0] = -84.820688, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1376910163, states[0] = -84.219382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387111850, states[0] = -43.052101, states[40]= 0.000079
Saving checkpoint... 
Iteration: 1398730778, states[0] = -84.774511, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1408685862, states[0] = -84.499276, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1419912595, states[0] = -84.259624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431936648, states[0] = -84.504917, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1443703110, states[0] = -84.625043, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1455931592, states[0] = -84.461122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466865711, states[0] = -47.571759, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1478328081, states[0] = -2.848960, states[40]= 0.000246
Saving checkpoint... 
Iteration: 1489983320, states[0] = -84.782083, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.719253
 - CaMKt in component CaMK (millimolar): 0.081242
 - cass in component intracellular_ions (millimolar): 0.000121
 - nai in component intracellular_ions (millimolar): 6.968340
 - nass in component intracellular_ions (millimolar): 6.968543
 - ki in component intracellular_ions (millimolar): 144.518020
 - kss in component intracellular_ions (millimolar): 144.517988
 - cansr in component intracellular_ions (millimolar): 2.458751
 - cajsr in component intracellular_ions (millimolar): 1.895942
 - cai in component intracellular_ions (millimolar): 0.000119
 - m in component INa (dimensionless): 0.010086
 - hf in component INa (dimensionless): 0.579156
 - hs in component INa (dimensionless): 0.578803
 - j in component INa (dimensionless): 0.576574
 - hsp in component INa (dimensionless): 0.330879
 - jp in component INa (dimensionless): 0.572779
 - mL in component INaL (dimensionless): 0.000343
 - hL in component INaL (dimensionless): 0.293663
 - hLp in component INaL (dimensionless): 0.123036
 - a in component Ito (dimensionless): 0.001239
 - iF in component Ito (dimensionless): 0.999224
 - iS in component Ito (dimensionless): 0.253434
 - ap in component Ito (dimensionless): 0.000631
 - iFp in component Ito (dimensionless): 0.999224
 - iSp in component Ito (dimensionless): 0.280377
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.781249
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.981477
 - jca in component ICaL (dimensionless): 0.986210
 - ffp in component ICaL (dimensionless): 0.999999
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.010545
 - xrf in component IKr (dimensionless): 0.006986
 - xrs in component IKr (dimensionless): 0.772087
 - xs1 in component IKs (dimensionless): 0.464521
 - xs2 in component IKs (dimensionless): 0.000351
 - xk1 in component IK1 (dimensionless): 0.996751
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
17:51:25 (33305): called boinc_finish(0)

</stderr_txt>
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