𝕏

Task 55904120

Name HuVeMOp_20240703120444316973_ORdGradInc_k_26-Schmidt_333-conf_982_1
Workunit 26548036
Created 3 Jul 2024, 10:11:03 UTC
Sent 3 Jul 2024, 13:26:46 UTC
Report deadline 6 Jul 2024, 13:26:46 UTC
Received 3 Jul 2024, 22:46:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 49 min 52 sec
CPU time 1 hours 42 min 36 sec
Validate state Valid
Credit 47.19
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.79 MB
Peak swap size 4.13 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Schmidt_333-conf_982.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Schmidt_333-conf_982_1_r861975543_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Schmidt_333-conf_982_1_r861975543_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.864285
     * GNaL_b in INaL: 0.005757
     * Gto_b in Ito: 0.083703
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031997
     * GKs_b in IKs: 0.001973
     * GK1_b in IK1: 0.159420
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.154589
     * GKb_b in IKb: 0.003817
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029337
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12823172, states[0] = -84.928009, states[40]= 0.000001
Saving checkpoint... 
Iteration: 24436283, states[0] = -50.926439, states[40]= 0.000122
Saving checkpoint... 
Iteration: 35838066, states[0] = 28.806234, states[40]= 0.121050
Saving checkpoint... 
Iteration: 48872221, states[0] = 17.000290, states[40]= 0.000013
Saving checkpoint... 
Iteration: 60865618, states[0] = 20.155816, states[40]= 0.000006
Saving checkpoint... 
Iteration: 73460033, states[0] = -84.219411, states[40]= 0.000001
Saving checkpoint... 
Iteration: 86747257, states[0] = -32.780125, states[40]= 0.000297
Saving checkpoint... 
Iteration: 98132737, states[0] = -84.706504, states[40]= 0.000001
Saving checkpoint... 
Iteration: 111162992, states[0] = 28.332696, states[40]= 0.172735
Saving checkpoint... 
Iteration: 123278092, states[0] = -79.922629, states[40]= 0.000002
Saving checkpoint... 
Iteration: 135477989, states[0] = -84.944526, states[40]= 0.000001
Saving checkpoint... 
Iteration: 148571153, states[0] = -28.680106, states[40]= 0.000292
Saving checkpoint... 
Iteration: 159341338, states[0] = 27.329216, states[40]= 0.000410
Saving checkpoint... 
Iteration: 171790171, states[0] = -84.664790, states[40]= 0.000001
Saving checkpoint... 
Iteration: 183535294, states[0] = 9.803522, states[40]= 0.000052
Saving checkpoint... 
Iteration: 196601070, states[0] = -76.527508, states[40]= 0.000004
Saving checkpoint... 
Iteration: 208147237, states[0] = 35.311734, states[40]= 1.081088
Saving checkpoint... 
Iteration: 220085383, states[0] = -57.281746, states[40]= 0.000044
Saving checkpoint... 
Iteration: 232664279, states[0] = 28.419883, states[40]= 0.001235
Saving checkpoint... 
Iteration: 245885367, states[0] = -15.248190, states[40]= 0.000300
Saving checkpoint... 
Iteration: 258664358, states[0] = 27.475514, states[40]= 0.000470
Saving checkpoint... 
Iteration: 271539436, states[0] = -1.784948, states[40]= 0.000277
Saving checkpoint... 
Iteration: 283899320, states[0] = -40.045686, states[40]= 0.000205
Saving checkpoint... 
Iteration: 296637808, states[0] = 32.037044, states[40]= 0.328675
Saving checkpoint... 
Iteration: 308477278, states[0] = 28.457864, states[40]= 0.134693
Saving checkpoint... 
Iteration: 321577256, states[0] = -60.054191, states[40]= 0.000033
Saving checkpoint... 
Iteration: 333894942, states[0] = -40.865837, states[40]= 0.000195
Saving checkpoint... 
Iteration: 345890805, states[0] = -36.951031, states[40]= 0.000243
Saving checkpoint... 
Iteration: 358690054, states[0] = 5.322153, states[40]= 0.000120
Saving checkpoint... 
Iteration: 370859489, states[0] = 1.695686, states[40]= 0.000200
Saving checkpoint... 
Iteration: 384313777, states[0] = 28.972348, states[40]= 0.002555
Saving checkpoint... 
Iteration: 397881243, states[0] = -31.036084, states[40]= 0.000289
Saving checkpoint... 
Iteration: 409898442, states[0] = -55.518891, states[40]= 0.000053
Saving checkpoint... 
Iteration: 421399023, states[0] = -57.861897, states[40]= 0.000042
Saving checkpoint... 
Iteration: 435359602, states[0] = -5.632196, states[40]= 0.000339
Saving checkpoint... 
Iteration: 447410837, states[0] = -78.375505, states[40]= 0.000003
Saving checkpoint... 
Iteration: 459840229, states[0] = 10.378380, states[40]= 0.000046
Saving checkpoint... 
Iteration: 472264653, states[0] = -84.747298, states[40]= 0.000001
Saving checkpoint... 
Iteration: 484528145, states[0] = -15.198059, states[40]= 0.000300
Saving checkpoint... 
Iteration: 497263475, states[0] = -84.768387, states[40]= 0.000001
Saving checkpoint... 
Iteration: 510539419, states[0] = -34.803362, states[40]= 0.000265
Saving checkpoint... 
Iteration: 522199097, states[0] = -26.805293, states[40]= 0.000287
Saving checkpoint... 
Iteration: 535356242, states[0] = -14.971150, states[40]= 0.000302
Saving checkpoint... 
Iteration: 547980637, states[0] = 21.628846, states[40]= 0.000008
Saving checkpoint... 
Iteration: 560868075, states[0] = -35.287423, states[40]= 0.000261
Saving checkpoint... 
Iteration: 572955849, states[0] = 29.490819, states[40]= 0.020957
Saving checkpoint... 
Iteration: 583382389, states[0] = -57.261938, states[40]= 0.000044
Saving checkpoint... 
Iteration: 595342887, states[0] = -4.723042, states[40]= 0.000330
Saving checkpoint... 
Iteration: 606972175, states[0] = 23.042967, states[40]= 0.000018
Saving checkpoint... 
Iteration: 618268195, states[0] = -84.974052, states[40]= 0.000001
Saving checkpoint... 
Iteration: 630472076, states[0] = 21.804094, states[40]= 0.000009
Saving checkpoint... 
Iteration: 642582855, states[0] = -84.769093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 654011640, states[0] = -15.837454, states[40]= 0.000293
Saving checkpoint... 
Iteration: 665431068, states[0] = -84.981063, states[40]= 0.000001
Saving checkpoint... 
Iteration: 677536587, states[0] = -53.155207, states[40]= 0.000068
Saving checkpoint... 
Iteration: 688219730, states[0] = -77.916301, states[40]= 0.000003
Saving checkpoint... 
Iteration: 697573333, states[0] = -84.691740, states[40]= 0.000001
Saving checkpoint... 
Iteration: 708399072, states[0] = -84.460161, states[40]= 0.000001
Saving checkpoint... 
Iteration: 718291656, states[0] = 24.474853, states[40]= 0.000045
Saving checkpoint... 
Iteration: 728021146, states[0] = -39.438271, states[40]= 0.000212
Saving checkpoint... 
Iteration: 738381824, states[0] = -78.426999, states[40]= 0.000003
Saving checkpoint... 
Iteration: 749171015, states[0] = -19.096763, states[40]= 0.000273
Saving checkpoint... 
Iteration: 759355617, states[0] = -45.074100, states[40]= 0.000142
Saving checkpoint... 
Iteration: 769332658, states[0] = -14.679724, states[40]= 0.000305
Saving checkpoint... 
Iteration: 780324985, states[0] = -5.461262, states[40]= 0.000337
Saving checkpoint... 
Iteration: 791299133, states[0] = 15.876038, states[40]= 0.000012
Saving checkpoint... 
Iteration: 801034506, states[0] = -67.493077, states[40]= 0.000014
Saving checkpoint... 
Iteration: 811389614, states[0] = -84.499582, states[40]= 0.000001
Saving checkpoint... 
Iteration: 821473153, states[0] = 8.553904, states[40]= 0.000067
Saving checkpoint... 
Iteration: 832100852, states[0] = 29.279541, states[40]= 0.004373
Saving checkpoint... 
Iteration: 843030335, states[0] = -67.529931, states[40]= 0.000013
Saving checkpoint... 
Iteration: 853406299, states[0] = -84.904036, states[40]= 0.000001
Saving checkpoint... 
Iteration: 863579096, states[0] = -84.980872, states[40]= 0.000001
Saving checkpoint... 
Iteration: 874931679, states[0] = 28.909549, states[40]= 0.002287
Saving checkpoint... 
Iteration: 885835391, states[0] = -35.004302, states[40]= 0.000263
Saving checkpoint... 
Iteration: 896953738, states[0] = 16.837559, states[40]= 0.000009
Saving checkpoint... 
Iteration: 908496731, states[0] = -30.840418, states[40]= 0.000289
Saving checkpoint... 
Iteration: 919166128, states[0] = -35.993230, states[40]= 0.000253
Saving checkpoint... 
Iteration: 929310519, states[0] = -6.009892, states[40]= 0.000341
Saving checkpoint... 
Iteration: 939300095, states[0] = 4.085536, states[40]= 0.000145
Saving checkpoint... 
Iteration: 949119258, states[0] = 14.178005, states[40]= 0.000018
Saving checkpoint... 
Iteration: 959114645, states[0] = 16.548284, states[40]= 0.000010
Saving checkpoint... 
Iteration: 969316316, states[0] = -20.026305, states[40]= 0.000270
Saving checkpoint... 
Iteration: 978593892, states[0] = 26.865260, states[40]= 0.000271
Saving checkpoint... 
Iteration: 989617531, states[0] = 12.584166, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1000478195, states[0] = -17.584371, states[40]= 0.000280
Saving checkpoint... 
Iteration: 1010565535, states[0] = -84.983379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1022087713, states[0] = 27.606293, states[40]= 0.000522
Saving checkpoint... 
Iteration: 1032910530, states[0] = 29.536279, states[40]= 0.016273
Saving checkpoint... 
Iteration: 1044477387, states[0] = -22.788398, states[40]= 0.000271
Saving checkpoint... 
Iteration: 1056018385, states[0] = -80.103988, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1067666266, states[0] = -55.816775, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1080413442, states[0] = 28.242547, states[40]= 0.000988
Saving checkpoint... 
Iteration: 1090549758, states[0] = -84.895253, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1102140512, states[0] = -25.934020, states[40]= 0.000281
Saving checkpoint... 
Iteration: 1112569604, states[0] = 29.545665, states[40]= 0.014169
Saving checkpoint... 
Iteration: 1123452451, states[0] = 0.161969, states[40]= 0.000236
Saving checkpoint... 
Iteration: 1132988012, states[0] = -49.105472, states[40]= 0.000099
Saving checkpoint... 
Iteration: 1143289054, states[0] = -5.912688, states[40]= 0.000339
Saving checkpoint... 
Iteration: 1154228525, states[0] = 29.106266, states[40]= 0.053433
Saving checkpoint... 
Iteration: 1165917917, states[0] = 22.155868, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1176543288, states[0] = -84.914333, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1187167597, states[0] = -74.892291, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1197714223, states[0] = 30.296482, states[40]= 0.146024
Saving checkpoint... 
Iteration: 1207863437, states[0] = -84.789438, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1218313023, states[0] = -49.375876, states[40]= 0.000097
Saving checkpoint... 
Iteration: 1229362774, states[0] = -84.808323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1240133209, states[0] = -34.869872, states[40]= 0.000264
Saving checkpoint... 
Iteration: 1251784368, states[0] = -14.587885, states[40]= 0.000306
Saving checkpoint... 
Iteration: 1263575603, states[0] = 21.719821, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1274496246, states[0] = -79.795720, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1286030902, states[0] = -84.891521, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1296796147, states[0] = -37.465828, states[40]= 0.000236
Saving checkpoint... 
Iteration: 1307907619, states[0] = 19.923117, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1318167942, states[0] = -84.098703, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1329518751, states[0] = -84.792985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1340747438, states[0] = 13.728408, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1351450986, states[0] = -28.818561, states[40]= 0.000291
Saving checkpoint... 
Iteration: 1362896476, states[0] = 23.117527, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1374011221, states[0] = -84.746842, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1385094988, states[0] = -2.014721, states[40]= 0.000283
Saving checkpoint... 
Iteration: 1396323701, states[0] = -83.476454, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1407416506, states[0] = 7.023102, states[40]= 0.000089
Saving checkpoint... 
Iteration: 1418706139, states[0] = 29.549574, states[40]= 0.011840
Saving checkpoint... 
Iteration: 1429890603, states[0] = 22.668258, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1440820663, states[0] = -83.809686, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1450711544, states[0] = 27.603917, states[40]= 0.000516
Saving checkpoint... 
Iteration: 1460666189, states[0] = -84.692485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1471824552, states[0] = -84.501488, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1482049882, states[0] = 23.833599, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1492480097, states[0] = -83.268025, states[40]= 0.000001
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.829835
 - CaMKt in component CaMK (millimolar): 0.216428
 - cass in component intracellular_ions (millimolar): 0.000172
 - nai in component intracellular_ions (millimolar): 7.263215
 - nass in component intracellular_ions (millimolar): 7.263568
 - ki in component intracellular_ions (millimolar): 143.859427
 - kss in component intracellular_ions (millimolar): 143.859392
 - cansr in component intracellular_ions (millimolar): 3.334326
 - cajsr in component intracellular_ions (millimolar): 1.930000
 - cai in component intracellular_ions (millimolar): 0.000161
 - m in component INa (dimensionless): 0.009974
 - hf in component INa (dimensionless): 0.583568
 - hs in component INa (dimensionless): 0.582485
 - j in component INa (dimensionless): 0.552398
 - hsp in component INa (dimensionless): 0.330911
 - jp in component INa (dimensionless): 0.510456
 - mL in component INaL (dimensionless): 0.000336
 - hL in component INaL (dimensionless): 0.182158
 - hLp in component INaL (dimensionless): 0.074194
 - a in component Ito (dimensionless): 0.001230
 - iF in component Ito (dimensionless): 0.999235
 - iS in component Ito (dimensionless): 0.131234
 - ap in component Ito (dimensionless): 0.000627
 - iFp in component Ito (dimensionless): 0.999235
 - iSp in component Ito (dimensionless): 0.146638
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.678014
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.928956
 - jca in component ICaL (dimensionless): 0.911755
 - ffp in component ICaL (dimensionless): 0.998935
 - fcafp in component ICaL (dimensionless): 0.999941
 - nca in component ICaL (dimensionless): 0.041880
 - xrf in component IKr (dimensionless): 0.101234
 - xrs in component IKr (dimensionless): 0.873140
 - xs1 in component IKs (dimensionless): 0.570082
 - xs2 in component IKs (dimensionless): 0.007224
 - xk1 in component IK1 (dimensionless): 0.996741
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
18:27:29 (33558): called boinc_finish(0)

</stderr_txt>
]]>