𝕏

Task 55899200

Name HuVeMOp_20240703120444316973_ORdGradInc_k_26-Drouin_MID_10000-conf_472_0
Workunit 26545583
Created 3 Jul 2024, 10:08:13 UTC
Sent 3 Jul 2024, 12:53:05 UTC
Report deadline 6 Jul 2024, 12:53:05 UTC
Received 3 Jul 2024, 18:41:16 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239403
Run time 4 hours 19 min 9 sec
CPU time 42 min 58 sec
Validate state Valid
Credit 44.39
Device peak FLOPS 5.89 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.21 MB
Peak swap size 5.20 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Drouin_MID_10000-conf_472.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Drouin_MID_10000-conf_472_0_r1546311322_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Drouin_MID_10000-conf_472_0_r1546311322_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.443021
     * GNaL_b in INaL: 0.005534
     * Gto_b in Ito: 0.080860
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031617
     * GKs_b in IKs: 0.001977
     * GK1_b in IK1: 0.165813
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.112908
     * GKb_b in IKb: 0.003824
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032612
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9836774, states[0] = -94.170546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16074834, states[0] = -94.186549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22414072, states[0] = -94.140529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28700022, states[0] = -94.132176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35072538, states[0] = 27.498979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40998995, states[0] = -94.184203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 47296419, states[0] = -94.147852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 53631530, states[0] = -94.151775, states[40]= 0.000001
Saving checkpoint... 
Iteration: 59634750, states[0] = -94.158488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65843933, states[0] = -94.195814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72100219, states[0] = -94.173780, states[40]= 0.000001
Saving checkpoint... 
Iteration: 78281244, states[0] = -94.170413, states[40]= 0.000001
Saving checkpoint... 
Iteration: 84646509, states[0] = -94.172954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90804427, states[0] = -94.205211, states[40]= 0.000000
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Iteration: 96783325, states[0] = -94.186757, states[40]= 0.000001
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Iteration: 103209087, states[0] = -94.178231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 109536884, states[0] = -94.179482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115739844, states[0] = -94.207394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122017661, states[0] = -94.188222, states[40]= 0.000001
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Iteration: 128058439, states[0] = -94.182639, states[40]= 0.000001
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Iteration: 134252184, states[0] = -94.182804, states[40]= 0.000001
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Iteration: 140414756, states[0] = -94.028888, states[40]= 0.000000
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Iteration: 146668811, states[0] = -94.195876, states[40]= 0.000001
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Iteration: 152709390, states[0] = -94.185983, states[40]= 0.000001
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Iteration: 158933933, states[0] = -94.184566, states[40]= 0.000001
Saving checkpoint... 
Iteration: 165150449, states[0] = -1.100374, states[40]= 0.000225
Saving checkpoint... 
Iteration: 171326861, states[0] = -94.204847, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177670323, states[0] = -94.187348, states[40]= 0.000001
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Iteration: 183737599, states[0] = -94.185566, states[40]= 0.000001
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Iteration: 189835612, states[0] = -94.186533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195955572, states[0] = -94.215590, states[40]= 0.000001
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Iteration: 202215076, states[0] = -94.190917, states[40]= 0.000001
Saving checkpoint... 
Iteration: 208777432, states[0] = -94.186090, states[40]= 0.000001
Saving checkpoint... 
Iteration: 215072047, states[0] = 26.423726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221130946, states[0] = -94.211406, states[40]= 0.000001
Saving checkpoint... 
Iteration: 227530093, states[0] = -94.188960, states[40]= 0.000001
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Iteration: 233596172, states[0] = -94.186361, states[40]= 0.000001
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Iteration: 239885696, states[0] = -94.187241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246191969, states[0] = -94.209780, states[40]= 0.000001
Saving checkpoint... 
Iteration: 252624917, states[0] = -94.188582, states[40]= 0.000001
Saving checkpoint... 
Iteration: 258821600, states[0] = -94.186431, states[40]= 0.000001
Saving checkpoint... 
Iteration: 264802349, states[0] = -94.187207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271048805, states[0] = -94.213904, states[40]= 0.000001
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Iteration: 277162906, states[0] = -94.191831, states[40]= 0.000001
Saving checkpoint... 
Iteration: 283456095, states[0] = -94.186542, states[40]= 0.000001
Saving checkpoint... 
Iteration: 289634180, states[0] = -94.187009, states[40]= 0.000001
Saving checkpoint... 
Iteration: 295540294, states[0] = -94.165456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301731374, states[0] = -94.197343, states[40]= 0.000001
Saving checkpoint... 
Iteration: 307738250, states[0] = -94.188068, states[40]= 0.000001
Saving checkpoint... 
Iteration: 313873076, states[0] = -94.186407, states[40]= 0.000001
Saving checkpoint... 
Iteration: 319982303, states[0] = -94.187380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326239324, states[0] = -94.208385, states[40]= 0.000001
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Iteration: 332611342, states[0] = -94.188582, states[40]= 0.000001
Saving checkpoint... 
Iteration: 338896664, states[0] = -94.186352, states[40]= 0.000001
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Iteration: 345074887, states[0] = 25.473787, states[40]= 0.000000
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Iteration: 351228738, states[0] = -94.208617, states[40]= 0.000001
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Iteration: 357538520, states[0] = -94.188895, states[40]= 0.000001
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Iteration: 363972854, states[0] = -94.186306, states[40]= 0.000001
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Iteration: 370230662, states[0] = -31.437791, states[40]= 0.004399
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Iteration: 376545851, states[0] = -94.200636, states[40]= 0.000001
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Iteration: 383024852, states[0] = -94.186955, states[40]= 0.000001
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Iteration: 389125422, states[0] = -94.186306, states[40]= 0.000001
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Iteration: 395561870, states[0] = -94.175751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401659161, states[0] = -94.198332, states[40]= 0.000001
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Iteration: 408142093, states[0] = -94.186625, states[40]= 0.000001
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Iteration: 414510961, states[0] = -94.186546, states[40]= 0.000001
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Iteration: 420800339, states[0] = -94.215887, states[40]= 0.000000
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Iteration: 427251604, states[0] = -94.190654, states[40]= 0.000001
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Iteration: 433740574, states[0] = -94.186037, states[40]= 0.000001
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Iteration: 440060598, states[0] = 29.910538, states[40]= 0.000000
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Iteration: 446532183, states[0] = -94.200697, states[40]= 0.000001
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Iteration: 452704811, states[0] = -94.187775, states[40]= 0.000001
Saving checkpoint... 
Iteration: 459050853, states[0] = -94.186033, states[40]= 0.000001
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Iteration: 465279184, states[0] = -66.134425, states[40]= 0.000036
Saving checkpoint... 
Iteration: 471551418, states[0] = -94.200208, states[40]= 0.000001
Saving checkpoint... 
Iteration: 477766641, states[0] = -94.187440, states[40]= 0.000001
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Iteration: 483954088, states[0] = -94.185906, states[40]= 0.000001
Saving checkpoint... 
Iteration: 490432804, states[0] = -94.064236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496758989, states[0] = -94.196296, states[40]= 0.000001
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Iteration: 502989057, states[0] = -94.186646, states[40]= 0.000001
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Iteration: 509265500, states[0] = -94.186005, states[40]= 0.000001
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Iteration: 515667311, states[0] = -94.204747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521913560, states[0] = -94.193945, states[40]= 0.000001
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Iteration: 528145122, states[0] = -94.186217, states[40]= 0.000001
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Iteration: 534482055, states[0] = -94.186115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 540903869, states[0] = -94.216104, states[40]= 0.000001
Saving checkpoint... 
Iteration: 547234793, states[0] = -94.190393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 553660188, states[0] = -94.185642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 559691855, states[0] = -94.186255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 566244168, states[0] = -94.207473, states[40]= 0.000001
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Iteration: 572413526, states[0] = -94.188947, states[40]= 0.000001
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Iteration: 578690624, states[0] = -94.185552, states[40]= 0.000001
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Iteration: 584865259, states[0] = -94.186378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591000075, states[0] = -94.214209, states[40]= 0.000001
Saving checkpoint... 
Iteration: 597011207, states[0] = -94.192476, states[40]= 0.000001
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Iteration: 603250610, states[0] = -94.185790, states[40]= 0.000001
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Iteration: 609423972, states[0] = -94.185804, states[40]= 0.000001
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Iteration: 615370857, states[0] = -93.934372, states[40]= 0.000000
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Iteration: 621377432, states[0] = -94.203713, states[40]= 0.000001
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Iteration: 627556670, states[0] = -94.187898, states[40]= 0.000001
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Iteration: 633871091, states[0] = -94.185374, states[40]= 0.000001
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Iteration: 640186385, states[0] = -18.461742, states[40]= 0.001390
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Iteration: 646394907, states[0] = -94.203191, states[40]= 0.000001
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Iteration: 652764525, states[0] = -94.186856, states[40]= 0.000001
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Iteration: 658891507, states[0] = -94.185294, states[40]= 0.000001
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Iteration: 665180023, states[0] = -15.764300, states[40]= 0.000710
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Iteration: 671648821, states[0] = -94.197614, states[40]= 0.000001
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Iteration: 678249177, states[0] = -94.185538, states[40]= 0.000001
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Iteration: 684566840, states[0] = -94.185693, states[40]= 0.000001
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Iteration: 690909107, states[0] = -94.215543, states[40]= 0.000001
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Iteration: 697211017, states[0] = -94.190093, states[40]= 0.000001
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Iteration: 703437839, states[0] = -94.185244, states[40]= 0.000001
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Iteration: 709706013, states[0] = -94.185763, states[40]= 0.000001
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Iteration: 715760771, states[0] = -94.213335, states[40]= 0.000000
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Iteration: 721947230, states[0] = -94.192831, states[40]= 0.000001
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Iteration: 728157182, states[0] = -94.185518, states[40]= 0.000001
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Iteration: 734428286, states[0] = -94.185384, states[40]= 0.000001
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Iteration: 740771816, states[0] = -94.213789, states[40]= 0.000000
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Iteration: 747099525, states[0] = -94.190996, states[40]= 0.000001
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Iteration: 753421493, states[0] = -94.185088, states[40]= 0.000001
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Iteration: 759711759, states[0] = -94.185600, states[40]= 0.000001
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Iteration: 765707004, states[0] = -94.209059, states[40]= 0.000000
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Iteration: 771812088, states[0] = -94.194536, states[40]= 0.000001
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Iteration: 778243088, states[0] = -94.185208, states[40]= 0.000001
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Iteration: 784467220, states[0] = -94.185252, states[40]= 0.000001
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Iteration: 790593480, states[0] = -94.186492, states[40]= 0.000000
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Iteration: 796900154, states[0] = -94.193193, states[40]= 0.000001
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Iteration: 803124598, states[0] = -94.185324, states[40]= 0.000001
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Iteration: 809396536, states[0] = -94.185100, states[40]= 0.000001
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Iteration: 815523050, states[0] = -94.153686, states[40]= 0.000000
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Iteration: 821678906, states[0] = -94.196558, states[40]= 0.000001
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Iteration: 827939011, states[0] = -94.185680, states[40]= 0.000001
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Iteration: 834144898, states[0] = -94.184817, states[40]= 0.000001
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Iteration: 840233415, states[0] = -32.790196, states[40]= 0.003909
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Iteration: 846591423, states[0] = -94.198124, states[40]= 0.000001
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Iteration: 852841870, states[0] = -94.185897, states[40]= 0.000001
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Iteration: 859016208, states[0] = -94.184661, states[40]= 0.000001
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Iteration: 871648794, states[0] = -94.196937, states[40]= 0.000001
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Iteration: 877749845, states[0] = -94.186151, states[40]= 0.000001
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Iteration: 883850800, states[0] = -94.184522, states[40]= 0.000001
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Iteration: 890259595, states[0] = -49.841938, states[40]= 0.000457
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Iteration: 896255946, states[0] = -94.206026, states[40]= 0.000001
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Iteration: 902593152, states[0] = -94.186774, states[40]= 0.000001
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Iteration: 908821798, states[0] = -94.184433, states[40]= 0.000001
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Iteration: 970835630, states[0] = -94.214690, states[40]= 0.000000
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Iteration: 976978004, states[0] = -94.191585, states[40]= 0.000001
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Iteration: 1014008634, states[0] = -94.184132, states[40]= 0.000001
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Iteration: 1020247589, states[0] = -41.249696, states[40]= 0.001500
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Iteration: 1094801479, states[0] = -94.184571, states[40]= 0.000001
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Iteration: 1100854145, states[0] = -94.214386, states[40]= 0.000000
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Iteration: 1106983412, states[0] = -94.191079, states[40]= 0.000001
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Iteration: 1113190098, states[0] = -94.184155, states[40]= 0.000001
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Iteration: 1119432770, states[0] = -94.184083, states[40]= 0.000001
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Iteration: 1125574732, states[0] = -94.178630, states[40]= 0.000000
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Iteration: 1131681099, states[0] = -94.195470, states[40]= 0.000001
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Iteration: 1144029316, states[0] = -94.183701, states[40]= 0.000001
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Iteration: 1150264752, states[0] = -53.729747, states[40]= 0.000254
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Iteration: 1156394937, states[0] = -94.201464, states[40]= 0.000001
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Iteration: 1162844388, states[0] = -94.184838, states[40]= 0.000001
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Iteration: 1169314344, states[0] = -94.183807, states[40]= 0.000001
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Iteration: 1175497072, states[0] = -94.133804, states[40]= 0.000000
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Iteration: 1181660383, states[0] = -94.195674, states[40]= 0.000001
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Iteration: 1194311918, states[0] = -94.183721, states[40]= 0.000001
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Iteration: 1200459488, states[0] = -94.097136, states[40]= 0.000000
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Iteration: 1206592682, states[0] = -94.196881, states[40]= 0.000001
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Iteration: 1212635398, states[0] = -94.185515, states[40]= 0.000001
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Iteration: 1224885027, states[0] = -94.184233, states[40]= 0.000000
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Iteration: 1236974634, states[0] = -94.190745, states[40]= 0.000001
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Iteration: 1243058541, states[0] = -94.183971, states[40]= 0.000001
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Iteration: 1249361627, states[0] = -94.183577, states[40]= 0.000001
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Iteration: 1255533669, states[0] = -94.158600, states[40]= 0.000000
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Iteration: 1286869072, states[0] = -94.191961, states[40]= 0.000001
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Iteration: 1292527679, states[0] = -94.185804, states[40]= 0.000001
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Iteration: 1298814873, states[0] = -94.183110, states[40]= 0.000001
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Iteration: 1305263911, states[0] = -53.084213, states[40]= 0.000280
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Iteration: 1311456540, states[0] = -94.199458, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1317678357, states[0] = -94.184960, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1324018514, states[0] = -94.183086, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1330408729, states[0] = -94.020385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336634125, states[0] = -94.195638, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1342826618, states[0] = -94.184289, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1348744208, states[0] = -94.182937, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1354653218, states[0] = -94.183516, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1361065669, states[0] = -94.209901, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1367260705, states[0] = -94.187396, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1373466546, states[0] = -94.182951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1379719375, states[0] = -94.183507, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1385855755, states[0] = -94.213428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392019214, states[0] = -94.189690, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1398378308, states[0] = -94.182941, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1404951020, states[0] = -94.183706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411150519, states[0] = -94.207307, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1417253444, states[0] = -94.187287, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1423446083, states[0] = -94.182797, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1429695906, states[0] = -94.183310, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1436098780, states[0] = -94.208716, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1442270765, states[0] = -94.187059, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1448747426, states[0] = -94.182598, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1454895510, states[0] = -94.183466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461056946, states[0] = -94.209803, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1467367306, states[0] = -94.186234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1473571732, states[0] = -94.182552, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1479724702, states[0] = -94.183174, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1485827415, states[0] = -94.212847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492078288, states[0] = -94.188696, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1498160907, states[0] = -94.182901, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.059435
 - CaMKt in component CaMK (millimolar): 0.000847
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 7.650435
 - nass in component intracellular_ions (millimolar): 7.650575
 - ki in component intracellular_ions (millimolar): 144.227740
 - kss in component intracellular_ions (millimolar): 144.227729
 - cansr in component intracellular_ions (millimolar): 1.694979
 - cajsr in component intracellular_ions (millimolar): 1.695635
 - cai in component intracellular_ions (millimolar): 0.000097
 - m in component INa (dimensionless): 0.003940
 - hf in component INa (dimensionless): 0.864596
 - hs in component INa (dimensionless): 0.864596
 - j in component INa (dimensionless): 0.864596
 - hsp in component INa (dimensionless): 0.697468
 - jp in component INa (dimensionless): 0.864596
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706376
 - hLp in component INaL (dimensionless): 0.512455
 - a in component Ito (dimensionless): 0.000660
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.999845
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999849
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999986
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003818
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000006
 - xs1 in component IKs (dimensionless): 0.002903
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997550
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:50:30 (56520): called boinc_finish(0)

</stderr_txt>
]]>