𝕏

Task 55899187

Name HuVeMOp_20240703120444316973_ORdGradInc_k_26-Drouin_EPI_5000-conf_172_1
Workunit 26545576
Created 3 Jul 2024, 10:08:13 UTC
Sent 3 Jul 2024, 12:53:05 UTC
Report deadline 6 Jul 2024, 12:53:05 UTC
Received 4 Jul 2024, 8:43:17 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239403
Run time 3 hours 54 min 40 sec
CPU time 43 min 15 sec
Validate state Valid
Credit 43.22
Device peak FLOPS 5.89 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.21 MB
Peak swap size 5.20 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Drouin_EPI_5000-conf_172.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Drouin_EPI_5000-conf_172_1_r1570793037_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Drouin_EPI_5000-conf_172_1_r1570793037_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.115536
     * GNaL_b in INaL: 0.005663
     * Gto_b in Ito: 0.087607
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031364
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.160979
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.468839
     * GKb_b in IKb: 0.003836
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030283
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10445046, states[0] = -94.316061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17443073, states[0] = -94.274389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24085267, states[0] = -94.253647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30883823, states[0] = -94.256064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37759905, states[0] = -93.868075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44451014, states[0] = -94.211348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50939893, states[0] = -94.235730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57920332, states[0] = -94.186550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64868343, states[0] = -94.203406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71815093, states[0] = -94.211344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78761916, states[0] = -94.225895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85634644, states[0] = -94.247250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92513540, states[0] = 22.290381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99387338, states[0] = -94.215515, states[40]= 0.000000
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Iteration: 106317743, states[0] = -94.229272, states[40]= 0.000000
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Iteration: 113369756, states[0] = -94.247538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120390680, states[0] = -94.171380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127090485, states[0] = -94.216258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133861661, states[0] = -94.230992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140591576, states[0] = -94.251956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147555953, states[0] = 23.856259, states[40]= 0.000000
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Iteration: 154502874, states[0] = -94.219131, states[40]= 0.000000
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Iteration: 161429007, states[0] = -94.230531, states[40]= 0.000000
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Iteration: 168390181, states[0] = -94.250322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175110011, states[0] = -1.438431, states[40]= 0.000229
Saving checkpoint... 
Iteration: 181776936, states[0] = -94.223366, states[40]= 0.000000
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Iteration: 188714606, states[0] = -94.237626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195557710, states[0] = -94.249764, states[40]= 0.000000
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Iteration: 202274749, states[0] = -94.216812, states[40]= 0.000000
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Iteration: 208988174, states[0] = -94.229659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215634585, states[0] = -94.256032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222542927, states[0] = 26.087286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229613216, states[0] = -94.218601, states[40]= 0.000000
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Iteration: 236655008, states[0] = -94.225842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243579598, states[0] = -94.242693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250644484, states[0] = -94.256212, states[40]= 0.000000
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Iteration: 257892956, states[0] = -94.176743, states[40]= 0.000000
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Iteration: 264749478, states[0] = -94.216875, states[40]= 0.000000
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Iteration: 272018898, states[0] = -94.219553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279170749, states[0] = -94.225242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285876807, states[0] = -94.250960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292695278, states[0] = -93.099423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299607095, states[0] = -94.218193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306280834, states[0] = -94.234974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313118279, states[0] = -94.254697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319988241, states[0] = -94.214217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326908412, states[0] = -94.220654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333802480, states[0] = -94.234035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340915201, states[0] = -94.248819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347979548, states[0] = -94.230192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354682063, states[0] = -94.216803, states[40]= 0.000000
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Iteration: 361632439, states[0] = -94.225273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368427751, states[0] = -94.248013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375165788, states[0] = -59.806942, states[40]= 0.000031
Saving checkpoint... 
Iteration: 382404515, states[0] = -94.214322, states[40]= 0.000000
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Iteration: 389203821, states[0] = -94.223569, states[40]= 0.000000
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Iteration: 395847921, states[0] = -94.251125, states[40]= 0.000000
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Iteration: 402826698, states[0] = -94.078548, states[40]= 0.000000
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Iteration: 409827690, states[0] = -94.214758, states[40]= 0.000000
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Iteration: 416772133, states[0] = -94.222032, states[40]= 0.000000
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Iteration: 423454445, states[0] = -94.246323, states[40]= 0.000000
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Iteration: 430416688, states[0] = -94.195561, states[40]= 0.000000
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Iteration: 437389003, states[0] = -94.213920, states[40]= 0.000000
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Iteration: 444342570, states[0] = -94.220556, states[40]= 0.000000
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Iteration: 451344815, states[0] = -94.231603, states[40]= 0.000000
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Iteration: 457811368, states[0] = -94.042850, states[40]= 0.000000
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Iteration: 464733237, states[0] = -94.215168, states[40]= 0.000000
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Iteration: 471532529, states[0] = -94.226424, states[40]= 0.000000
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Iteration: 478481632, states[0] = -94.244614, states[40]= 0.000000
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Iteration: 485405798, states[0] = -94.186324, states[40]= 0.000000
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Iteration: 492343380, states[0] = -94.213796, states[40]= 0.000000
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Iteration: 499315846, states[0] = -94.220459, states[40]= 0.000000
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Iteration: 505867392, states[0] = -94.249244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512608533, states[0] = -0.416777, states[40]= 0.000207
Saving checkpoint... 
Iteration: 519529325, states[0] = -94.217051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526376937, states[0] = -94.229929, states[40]= 0.000000
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Iteration: 533169310, states[0] = -94.254011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540184444, states[0] = -85.930882, states[40]= 0.000001
Saving checkpoint... 
Iteration: 546919065, states[0] = -94.218341, states[40]= 0.000000
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Iteration: 553879505, states[0] = -94.229585, states[40]= 0.000000
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Iteration: 560879810, states[0] = -94.248181, states[40]= 0.000000
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Iteration: 567932983, states[0] = -94.205388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575044123, states[0] = 25.964778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581752358, states[0] = -94.220763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588544904, states[0] = -94.240872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595448979, states[0] = -94.214274, states[40]= 0.000000
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Iteration: 602204978, states[0] = -94.214117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608912656, states[0] = -94.228120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615677723, states[0] = -94.253256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622535277, states[0] = 26.385297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629570327, states[0] = -94.215435, states[40]= 0.000000
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Iteration: 636340013, states[0] = -94.229926, states[40]= 0.000000
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Iteration: 643193622, states[0] = -94.252981, states[40]= 0.000000
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Iteration: 650197981, states[0] = -93.321520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656918006, states[0] = -94.217276, states[40]= 0.000000
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Iteration: 663811746, states[0] = -94.230515, states[40]= 0.000000
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Iteration: 670689820, states[0] = -94.252726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677453883, states[0] = -94.210996, states[40]= 0.000000
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Iteration: 684124415, states[0] = -94.222275, states[40]= 0.000000
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Iteration: 690950598, states[0] = -94.243863, states[40]= 0.000000
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Iteration: 697713882, states[0] = -93.585236, states[40]= 0.000000
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Iteration: 704494623, states[0] = -94.215701, states[40]= 0.000000
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Iteration: 711479133, states[0] = -94.225367, states[40]= 0.000000
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Iteration: 718462087, states[0] = -94.243095, states[40]= 0.000000
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Iteration: 725541335, states[0] = -94.242611, states[40]= 0.000000
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Iteration: 732416385, states[0] = -94.210772, states[40]= 0.000000
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Iteration: 739039509, states[0] = -94.223625, states[40]= 0.000000
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Iteration: 745777356, states[0] = -94.250286, states[40]= 0.000000
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Iteration: 752407600, states[0] = -94.210651, states[40]= 0.000000
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Iteration: 759352691, states[0] = -94.217287, states[40]= 0.000000
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Iteration: 766253876, states[0] = -94.231354, states[40]= 0.000000
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Iteration: 773022708, states[0] = -94.238492, states[40]= 0.000000
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Iteration: 779984308, states[0] = -94.209735, states[40]= 0.000000
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Iteration: 786974820, states[0] = -94.215163, states[40]= 0.000000
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Iteration: 793965792, states[0] = -94.224892, states[40]= 0.000000
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Iteration: 800877358, states[0] = -94.245927, states[40]= 0.000000
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Iteration: 807066048, states[0] = -94.213740, states[40]= 0.000000
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Iteration: 814243146, states[0] = -94.218643, states[40]= 0.000000
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Iteration: 821488036, states[0] = -94.224058, states[40]= 0.000000
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Iteration: 828220715, states[0] = -94.250875, states[40]= 0.000000
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Iteration: 835400404, states[0] = -94.178158, states[40]= 0.000000
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Iteration: 842288794, states[0] = -94.210876, states[40]= 0.000000
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Iteration: 848936104, states[0] = -94.225126, states[40]= 0.000000
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Iteration: 855827001, states[0] = -94.247439, states[40]= 0.000000
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Iteration: 862746592, states[0] = -93.793424, states[40]= 0.000000
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Iteration: 869317351, states[0] = -94.216791, states[40]= 0.000000
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Iteration: 876086210, states[0] = -94.236378, states[40]= 0.000000
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Iteration: 883170584, states[0] = -94.250588, states[40]= 0.000000
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Iteration: 890134594, states[0] = -25.022946, states[40]= 0.000438
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Iteration: 896949711, states[0] = -94.214442, states[40]= 0.000000
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Iteration: 903907843, states[0] = -94.225350, states[40]= 0.000000
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Iteration: 910798091, states[0] = -94.247973, states[40]= 0.000000
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Iteration: 917629833, states[0] = -20.112884, states[40]= 0.000319
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Iteration: 924601400, states[0] = -94.212142, states[40]= 0.000000
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Iteration: 931392889, states[0] = -94.225495, states[40]= 0.000000
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Iteration: 938169716, states[0] = -94.250041, states[40]= 0.000000
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Iteration: 944955515, states[0] = -94.208346, states[40]= 0.000000
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Iteration: 950922795, states[0] = -94.242509, states[40]= 0.000000
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Iteration: 957809468, states[0] = -94.033060, states[40]= 0.000000
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Iteration: 964887111, states[0] = -94.208739, states[40]= 0.000000
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Iteration: 971794771, states[0] = -94.216168, states[40]= 0.000000
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Iteration: 978766320, states[0] = -94.228855, states[40]= 0.000000
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Iteration: 985737110, states[0] = -94.249018, states[40]= 0.000000
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Iteration: 992640961, states[0] = -31.690307, states[40]= 0.000497
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Iteration: 999834250, states[0] = -94.208881, states[40]= 0.000000
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Iteration: 1006452226, states[0] = -94.223151, states[40]= 0.000000
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Iteration: 1013306635, states[0] = -94.246658, states[40]= 0.000000
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Iteration: 1020257723, states[0] = -93.848471, states[40]= 0.000000
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Iteration: 1027050210, states[0] = -94.211776, states[40]= 0.000000
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Iteration: 1034088374, states[0] = -94.219607, states[40]= 0.000000
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Iteration: 1040691581, states[0] = -94.249085, states[40]= 0.000000
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Iteration: 1047727608, states[0] = -93.677644, states[40]= 0.000000
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Iteration: 1054669532, states[0] = -94.210053, states[40]= 0.000000
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Iteration: 1061687175, states[0] = -94.217272, states[40]= 0.000000
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Iteration: 1068981575, states[0] = -94.221784, states[40]= 0.000000
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Iteration: 1075862884, states[0] = -94.243831, states[40]= 0.000000
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Iteration: 1083230559, states[0] = -94.248196, states[40]= 0.000000
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Iteration: 1090215814, states[0] = -93.595524, states[40]= 0.000000
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Iteration: 1096745169, states[0] = -94.215824, states[40]= 0.000000
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Iteration: 1103439353, states[0] = -94.240293, states[40]= 0.000000
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Iteration: 1110202320, states[0] = -93.460672, states[40]= 0.000000
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Iteration: 1117017497, states[0] = -94.211325, states[40]= 0.000000
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Iteration: 1123695438, states[0] = -94.229840, states[40]= 0.000000
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Iteration: 1130991239, states[0] = -94.237792, states[40]= 0.000000
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Iteration: 1137979624, states[0] = -94.222466, states[40]= 0.000000
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Iteration: 1144699064, states[0] = -94.208839, states[40]= 0.000000
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Iteration: 1151643377, states[0] = -94.217274, states[40]= 0.000000
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Iteration: 1158398730, states[0] = -94.241508, states[40]= 0.000000
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Iteration: 1165313227, states[0] = -94.040429, states[40]= 0.000000
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Iteration: 1172587152, states[0] = 11.953845, states[40]= 0.000024
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Iteration: 1179440832, states[0] = -94.211789, states[40]= 0.000000
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Iteration: 1186401858, states[0] = -94.222736, states[40]= 0.000000
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Iteration: 1193031326, states[0] = -94.236166, states[40]= 0.000000
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Iteration: 1200008484, states[0] = 19.456964, states[40]= 0.000000
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Iteration: 1206675889, states[0] = -94.216071, states[40]= 0.000000
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Iteration: 1213384279, states[0] = -94.241584, states[40]= 0.000000
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Iteration: 1220287215, states[0] = -93.965029, states[40]= 0.000000
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Iteration: 1227122262, states[0] = -94.208908, states[40]= 0.000000
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Iteration: 1234186211, states[0] = -94.215595, states[40]= 0.000000
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Iteration: 1241247084, states[0] = -94.226909, states[40]= 0.000000
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Iteration: 1247842605, states[0] = -94.100553, states[40]= 0.000000
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Iteration: 1254860357, states[0] = -94.206126, states[40]= 0.000000
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Iteration: 1261674964, states[0] = -94.215547, states[40]= 0.000000
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Iteration: 1268680140, states[0] = -94.228960, states[40]= 0.000000
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Iteration: 1275614880, states[0] = -94.245091, states[40]= 0.000000
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Iteration: 1282593130, states[0] = 8.899773, states[40]= 0.000048
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Iteration: 1289587730, states[0] = -94.208715, states[40]= 0.000000
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Iteration: 1296360420, states[0] = -94.222832, states[40]= 0.000000
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Iteration: 1302948135, states[0] = -94.206875, states[40]= 0.000000
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Iteration: 1309745459, states[0] = -94.206716, states[40]= 0.000000
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Iteration: 1316580555, states[0] = -94.217004, states[40]= 0.000000
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Iteration: 1323540065, states[0] = -94.233851, states[40]= 0.000000
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Iteration: 1330548740, states[0] = -94.237897, states[40]= 0.000000
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Iteration: 1337515654, states[0] = 23.044579, states[40]= 0.000000
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Iteration: 1344214836, states[0] = -94.213959, states[40]= 0.000000
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Iteration: 1350931393, states[0] = -94.238210, states[40]= 0.000000
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Iteration: 1357788970, states[0] = -93.969474, states[40]= 0.000000
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Iteration: 1364974959, states[0] = -94.204049, states[40]= 0.000000
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Iteration: 1372116118, states[0] = -94.207556, states[40]= 0.000000
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Iteration: 1379247725, states[0] = -94.212999, states[40]= 0.000000
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Iteration: 1386196515, states[0] = -94.227222, states[40]= 0.000000
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Iteration: 1392633666, states[0] = -24.059660, states[40]= 0.000412
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Iteration: 1399555851, states[0] = -94.208038, states[40]= 0.000000
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Iteration: 1406651313, states[0] = -94.214601, states[40]= 0.000000
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Iteration: 1413537229, states[0] = -94.233082, states[40]= 0.000000
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Iteration: 1420197453, states[0] = -93.280606, states[40]= 0.000000
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Iteration: 1427136480, states[0] = -94.206769, states[40]= 0.000000
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Iteration: 1434101970, states[0] = -94.215373, states[40]= 0.000000
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Iteration: 1440957648, states[0] = -94.236188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447718257, states[0] = -93.609500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454792417, states[0] = -94.204807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461470543, states[0] = -94.218203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468363186, states[0] = -94.239966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475199105, states[0] = -93.365732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482008078, states[0] = -94.207857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489120407, states[0] = -94.214434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496124775, states[0] = -94.228779, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.078490
 - CaMKt in component CaMK (millimolar): 0.001696
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.050467
 - nass in component intracellular_ions (millimolar): 7.050603
 - ki in component intracellular_ions (millimolar): 144.646549
 - kss in component intracellular_ions (millimolar): 144.646536
 - cansr in component intracellular_ions (millimolar): 2.393306
 - cajsr in component intracellular_ions (millimolar): 2.393673
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003932
 - hf in component INa (dimensionless): 0.864962
 - hs in component INa (dimensionless): 0.864963
 - j in component INa (dimensionless): 0.864965
 - hsp in component INa (dimensionless): 0.698130
 - jp in component INa (dimensionless): 0.864966
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706932
 - hLp in component INaL (dimensionless): 0.513109
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.999849
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999849
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998796
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005287
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001785
 - xs1 in component IKs (dimensionless): 0.023677
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997545
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:43:05 (54452): called boinc_finish(0)

</stderr_txt>
]]>


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