𝕏

Task 55895109

Name HuVeMOp_20240703120444316973_ORdGradInc_k_26-Pueyo_APDR-conf_233_0
Workunit 26543538
Created 3 Jul 2024, 10:06:03 UTC
Sent 3 Jul 2024, 12:25:15 UTC
Report deadline 6 Jul 2024, 22:01:15 UTC
Received 3 Jul 2024, 17:45:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239811
Run time 1 hours 51 min 41 sec
CPU time 1 hours 38 min 10 sec
Validate state Valid
Credit 56.81
Device peak FLOPS 3.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.73 MB
Peak swap size 5.29 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Pueyo_APDR-conf_233.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Pueyo_APDR-conf_233_0_r1925027982_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Pueyo_APDR-conf_233_0_r1925027982_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.455425
     * GNaL_b in INaL: 0.005616
     * Gto_b in Ito: 0.087703
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032200
     * GKs_b in IKs: 0.001972
     * GK1_b in IK1: 0.162242
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.069133
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030393
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 22062020, states[0] = 5.061924, states[40]= 0.004726
Saving checkpoint... 
Iteration: 45301952, states[0] = -95.004883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66276393, states[0] = -94.968277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87095668, states[0] = -16.779712, states[40]= 0.001249
Saving checkpoint... 
Iteration: 109046379, states[0] = 12.613205, states[40]= 0.005007


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Pueyo_APDR-conf_233.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Pueyo_APDR-conf_233_0_r1925027982_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Pueyo_APDR-conf_233_0_r1925027982_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.455425
     * GNaL_b in INaL: 0.005616
     * Gto_b in Ito: 0.087703
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032200
     * GKs_b in IKs: 0.001972
     * GK1_b in IK1: 0.162242
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.069133
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030393
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 109046379
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 12.613205 (After loading)
 - states[40]: 0.005007 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 128053225, states[0] = 9.973767, states[40]= 0.004902
Saving checkpoint... 
Iteration: 146931346, states[0] = -95.033289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169820081, states[0] = -94.988493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188059827, states[0] = 7.279170, states[40]= 0.004814
Saving checkpoint... 
Iteration: 205449844, states[0] = -95.035908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222523053, states[0] = 20.194675, states[40]= 0.007704
Saving checkpoint... 
Iteration: 245741353, states[0] = -94.910381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261071169, states[0] = 1.968008, states[40]= 0.004471
Saving checkpoint... 
Iteration: 278931331, states[0] = -95.031816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301934246, states[0] = -95.032432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315502414, states[0] = 41.286360, states[40]= 0.111996
Saving checkpoint... 
Iteration: 337714234, states[0] = -94.865825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360199217, states[0] = -94.836217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378084695, states[0] = -6.618356, states[40]= 0.003055
Saving checkpoint... 
Iteration: 399276888, states[0] = -94.952817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418752148, states[0] = -94.924810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440681184, states[0] = -94.790099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458792299, states[0] = -94.966958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479560937, states[0] = 6.808239, states[40]= 0.004795
Saving checkpoint... 
Iteration: 494489563, states[0] = -95.041738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513859140, states[0] = -95.008488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533792057, states[0] = -94.966703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551828437, states[0] = -94.992689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574780238, states[0] = -94.955975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597926703, states[0] = -95.030515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620873098, states[0] = -95.014192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643068741, states[0] = 3.201612, states[40]= 0.004581
Saving checkpoint... 
Iteration: 664506433, states[0] = 25.156397, states[40]= 0.120085


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Pueyo_APDR-conf_233.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Pueyo_APDR-conf_233_0_r1925027982_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Pueyo_APDR-conf_233_0_r1925027982_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.455425
     * GNaL_b in INaL: 0.005616
     * Gto_b in Ito: 0.087703
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032200
     * GKs_b in IKs: 0.001972
     * GK1_b in IK1: 0.162242
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.069133
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030393
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 664506433
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 25.156397 (After loading)
 - states[40]: 0.120085 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 682252959, states[0] = -94.925670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703483772, states[0] = -95.040826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725716586, states[0] = -94.869878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747655606, states[0] = -84.151101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769509773, states[0] = 22.760289, states[40]= 0.056178
Saving checkpoint... 
Iteration: 791635199, states[0] = -55.868158, states[40]= 0.000010
Saving checkpoint... 
Iteration: 814046376, states[0] = 12.683210, states[40]= 0.005006
Saving checkpoint... 
Iteration: 836289521, states[0] = -94.964314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858022475, states[0] = 20.327403, states[40]= 0.007969
Saving checkpoint... 
Iteration: 879846992, states[0] = -95.002557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901718720, states[0] = -94.873600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923974291, states[0] = -95.039317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945597399, states[0] = -17.969924, states[40]= 0.001127
Saving checkpoint... 
Iteration: 967923179, states[0] = -95.029431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990258696, states[0] = -94.932545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012954347, states[0] = -95.035959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034457481, states[0] = -95.036505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054683180, states[0] = -94.797409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075396335, states[0] = -95.021971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097505874, states[0] = 26.026454, states[40]= 0.133155
Saving checkpoint... 
Iteration: 1114820321, states[0] = -94.987301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130583725, states[0] = -5.872604, states[40]= 0.003214
Saving checkpoint... 
Iteration: 1151673456, states[0] = -94.699551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174322834, states[0] = -94.988858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189251732, states[0] = -94.923766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209520059, states[0] = 20.834936, states[40]= 0.009534
Saving checkpoint... 
Iteration: 1232503678, states[0] = 32.896985, states[40]= 0.154371
Saving checkpoint... 
Iteration: 1255813840, states[0] = -94.982904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279288118, states[0] = -94.962786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298447610, states[0] = -95.034511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316701036, states[0] = -94.839345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336799032, states[0] = -94.971914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355987568, states[0] = -95.040910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378075342, states[0] = -0.321019, states[40]= 0.004203
Saving checkpoint... 
Iteration: 1401380753, states[0] = -95.016537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422628575, states[0] = -48.637872, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1444398166, states[0] = -95.022293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466761536, states[0] = -94.935584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486422672, states[0] = -95.028967, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Pueyo_APDR-conf_233.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Pueyo_APDR-conf_233_0_r1925027982_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Pueyo_APDR-conf_233_0_r1925027982_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.455425
     * GNaL_b in INaL: 0.005616
     * Gto_b in Ito: 0.087703
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032200
     * GKs_b in IKs: 0.001972
     * GK1_b in IK1: 0.162242
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.069133
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030393
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1486422672
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.028967 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1509510672, states[0] = -95.178872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531232255, states[0] = 16.201625, states[40]= 0.006719
Saving checkpoint... 
Iteration: 1551936926, states[0] = 13.929484, states[40]= 0.006245
Saving checkpoint... 
Iteration: 1571268805, states[0] = -95.131679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1593734090, states[0] = -86.647292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616094645, states[0] = -95.319985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637223488, states[0] = -68.701758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1657231157, states[0] = 16.328414, states[40]= 0.006844
Saving checkpoint... 
Iteration: 1678421781, states[0] = -95.246614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1701191200, states[0] = -95.192271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1721891183, states[0] = -95.192274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742490368, states[0] = -28.597701, states[40]= 0.000520
Saving checkpoint... 
Iteration: 1761801014, states[0] = -95.211824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1782433968, states[0] = -86.808620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803614922, states[0] = -38.824789, states[40]= 0.000165
Saving checkpoint... 
Iteration: 1824933692, states[0] = -95.065697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846640526, states[0] = -63.477831, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1866813373, states[0] = -94.992200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1888523991, states[0] = 19.922759, states[40]= 0.007325
Saving checkpoint... 
Iteration: 1908361765, states[0] = -95.011584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1930996127, states[0] = -95.043061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953301163, states[0] = -94.973907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972051798, states[0] = 10.577858, states[40]= 0.004919
Saving checkpoint... 
Iteration: 1987901200, states[0] = -95.023073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008840923, states[0] = -94.998807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029201827, states[0] = -94.840522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048395689, states[0] = -95.021120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067924824, states[0] = -95.029073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088141415, states[0] = -63.019835, states[40]= 0.000003
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.917805
 - CaMKt in component CaMK (millimolar): 0.007013
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.559002
 - nass in component intracellular_ions (millimolar): 6.559063
 - ki in component intracellular_ions (millimolar): 145.417622
 - kss in component intracellular_ions (millimolar): 145.417602
 - cansr in component intracellular_ions (millimolar): 1.315351
 - cajsr in component intracellular_ions (millimolar): 1.277424
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003613
 - hf in component INa (dimensionless): 0.880277
 - hs in component INa (dimensionless): 0.880273
 - j in component INa (dimensionless): 0.880243
 - hsp in component INa (dimensionless): 0.726351
 - jp in component INa (dimensionless): 0.880224
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710594
 - hLp in component INaL (dimensionless): 0.453246
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622645
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697909
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936784
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001616
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.328172
 - xs1 in component IKs (dimensionless): 0.238968
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997333
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:45:45 (17748): called boinc_finish(0)

</stderr_txt>
]]>