𝕏

Task 55893463

Name HuVeMOp_20240703120444316973_ORdGradInc_k_26-Drouin_EPI_3000-conf_807_1
Workunit 26542718
Created 3 Jul 2024, 10:05:01 UTC
Sent 3 Jul 2024, 12:08:02 UTC
Report deadline 6 Jul 2024, 12:08:02 UTC
Received 3 Jul 2024, 20:31:46 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 50 min 59 sec
CPU time 1 hours 42 min 55 sec
Validate state Valid
Credit 45.18
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.76 MB
Peak swap size 4.13 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Drouin_EPI_3000-conf_807.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Drouin_EPI_3000-conf_807_1_r2044267096_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Drouin_EPI_3000-conf_807_1_r2044267096_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.082995
     * GNaL_b in INaL: 0.005646
     * Gto_b in Ito: 0.081063
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032125
     * GKs_b in IKs: 0.001971
     * GK1_b in IK1: 0.160451
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 71.608498
     * GKb_b in IKb: 0.003817
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033817
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10510745, states[0] = 20.800221, states[40]= 0.056121
Saving checkpoint... 
Iteration: 21405538, states[0] = -94.275273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32087740, states[0] = -94.312317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43269009, states[0] = -94.284969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53807057, states[0] = -94.283803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64685152, states[0] = -92.146451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75429745, states[0] = -94.272270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85969422, states[0] = -94.294525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96082542, states[0] = 12.634017, states[40]= 0.000017
Saving checkpoint... 
Iteration: 106863016, states[0] = -94.220162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117217659, states[0] = -93.717917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128412112, states[0] = -94.318225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139391874, states[0] = -94.298744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150262707, states[0] = -93.975717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161647760, states[0] = -94.308938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172146755, states[0] = -94.309211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182642635, states[0] = -94.309513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193932351, states[0] = -94.286782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204977041, states[0] = -94.317240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215787144, states[0] = -94.303717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227208680, states[0] = -94.328889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237878701, states[0] = -94.321867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247610658, states[0] = -6.093910, states[40]= 0.000245
Saving checkpoint... 
Iteration: 257816845, states[0] = -94.302180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269289284, states[0] = -94.325638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281645748, states[0] = -94.308554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292777968, states[0] = -94.035264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303223932, states[0] = -93.763966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315110479, states[0] = -5.932908, states[40]= 0.000243
Saving checkpoint... 
Iteration: 327215139, states[0] = -93.701914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339192471, states[0] = -93.452317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351005006, states[0] = 14.947467, states[40]= 0.697094
Saving checkpoint... 
Iteration: 363182403, states[0] = -91.626019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375610241, states[0] = -94.326143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387306805, states[0] = -94.120156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399693768, states[0] = -94.326573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411594935, states[0] = -94.324746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423619453, states[0] = -94.325720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436917937, states[0] = -94.274288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449085328, states[0] = -94.323480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460712342, states[0] = -93.678976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472345783, states[0] = -94.297730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483808516, states[0] = -94.321342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493904027, states[0] = -94.263009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504612178, states[0] = -94.324109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514070451, states[0] = -94.308134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524595062, states[0] = -94.306836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534831401, states[0] = -94.319448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545474295, states[0] = -94.312223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555029728, states[0] = 26.147374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565310515, states[0] = -94.297441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575807906, states[0] = -94.297363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585739039, states[0] = -94.322403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595243201, states[0] = -94.299460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605521247, states[0] = -94.308946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616178038, states[0] = -94.301730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627644043, states[0] = -94.322948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639285245, states[0] = -94.054278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650498776, states[0] = -94.309291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661927755, states[0] = -94.276943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672677957, states[0] = -94.322279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683389389, states[0] = -94.314186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694381625, states[0] = -94.292859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705765799, states[0] = -94.319484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716598060, states[0] = -94.303544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728056471, states[0] = -94.316117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739758983, states[0] = -93.951718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751655732, states[0] = -56.443318, states[40]= 0.000040
Saving checkpoint... 
Iteration: 763383784, states[0] = -94.291651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776003537, states[0] = -94.305870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788260447, states[0] = -94.318333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799987253, states[0] = -94.300986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811338733, states[0] = -94.292393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823157549, states[0] = -94.299187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834287135, states[0] = -94.057105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846607287, states[0] = -94.318272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858240376, states[0] = -93.855959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869870352, states[0] = -94.290343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880577816, states[0] = 14.705154, states[40]= 0.000010
Saving checkpoint... 
Iteration: 891713251, states[0] = -94.318100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903494111, states[0] = -94.301284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914030160, states[0] = -94.309203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925599017, states[0] = 2.979261, states[40]= 0.000113
Saving checkpoint... 
Iteration: 937141259, states[0] = -94.298009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948879917, states[0] = -94.310291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959539569, states[0] = -94.302249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970606967, states[0] = -2.856193, states[40]= 0.000210
Saving checkpoint... 
Iteration: 982518413, states[0] = 24.284322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994934352, states[0] = -94.275354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006336711, states[0] = -94.289246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017857814, states[0] = -94.310243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029682174, states[0] = -94.316377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042294810, states[0] = -94.290156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053184353, states[0] = -92.433290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065184349, states[0] = -92.431617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076781908, states[0] = -94.290060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088619398, states[0] = -94.296466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100440373, states[0] = -94.304777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113212209, states[0] = -93.666828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123886035, states[0] = -94.236547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136375806, states[0] = -94.307408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147872721, states[0] = -94.221932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159634367, states[0] = -31.468922, states[40]= 0.000371
Saving checkpoint... 
Iteration: 1171839417, states[0] = -94.174707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184097520, states[0] = -94.312210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196431610, states[0] = -94.303639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208112335, states[0] = -94.312557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219400718, states[0] = -94.283582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231797378, states[0] = -94.081100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242819056, states[0] = -94.308388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255508253, states[0] = 19.623665, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1267023693, states[0] = -94.297950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278263382, states[0] = -93.961923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289660053, states[0] = -94.291401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301618556, states[0] = -94.293000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313454140, states[0] = -94.300590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324822898, states[0] = -94.141204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336651970, states[0] = -52.012772, states[40]= 0.000069
Saving checkpoint... 
Iteration: 1348265442, states[0] = -94.286208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359401615, states[0] = -94.246771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371613613, states[0] = -94.309924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384368014, states[0] = -94.281950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396978335, states[0] = -94.288300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409070756, states[0] = -94.306467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421067861, states[0] = -94.305983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433334476, states[0] = -94.304533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445912765, states[0] = -94.279460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458153637, states[0] = -53.969969, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1470910279, states[0] = -94.300190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482804046, states[0] = -94.305118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494713168, states[0] = -94.308193, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.151866
 - CaMKt in component CaMK (millimolar): 0.003641
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 7.182554
 - nass in component intracellular_ions (millimolar): 7.182693
 - ki in component intracellular_ions (millimolar): 144.451981
 - kss in component intracellular_ions (millimolar): 144.451964
 - cansr in component intracellular_ions (millimolar): 2.449401
 - cajsr in component intracellular_ions (millimolar): 2.449979
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003903
 - hf in component INa (dimensionless): 0.866365
 - hs in component INa (dimensionless): 0.866366
 - j in component INa (dimensionless): 0.866373
 - hsp in component INa (dimensionless): 0.700671
 - jp in component INa (dimensionless): 0.866377
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709023
 - hLp in component INaL (dimensionless): 0.512951
 - a in component Ito (dimensionless): 0.000656
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.999851
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.999851
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.991130
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005194
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.025016
 - xs1 in component IKs (dimensionless): 0.068780
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997527
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:17:26 (32553): called boinc_finish(0)

</stderr_txt>
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