𝕏

Task 55893372

Name HuVeMOp_20240703120444316973_ORdGradInc_k_26-Pueyo_APDR-conf_705_0
Workunit 26542674
Created 3 Jul 2024, 10:05:01 UTC
Sent 3 Jul 2024, 12:10:31 UTC
Report deadline 6 Jul 2024, 21:46:31 UTC
Received 4 Jul 2024, 8:39:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231066
Run time 1 hours 47 min 46 sec
CPU time 1 hours 30 min 59 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 4.29 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 5.23 MB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Pueyo_APDR-conf_705.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Pueyo_APDR-conf_705_0_r1558807297_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703120444316973_ORdGradInc_k_26-Pueyo_APDR-conf_705_0_r1558807297_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.727552
     * GNaL_b in INaL: 0.005909
     * Gto_b in Ito: 0.088289
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031393
     * GKs_b in IKs: 0.001891
     * GK1_b in IK1: 0.165819
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.437040
     * GKb_b in IKb: 0.003808
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030067
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8048834, states[0] = 10.795225, states[40]= 0.004872
Saving checkpoint... 
Iteration: 19819537, states[0] = -95.045375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31793760, states[0] = -95.002876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43664364, states[0] = -92.720997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55777711, states[0] = -94.964225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67947749, states[0] = -95.039445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79938150, states[0] = -95.033198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90911914, states[0] = -95.024142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102481690, states[0] = -95.035917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114462731, states[0] = -95.031479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126526291, states[0] = 19.743490, states[40]= 0.006479
Saving checkpoint... 
Iteration: 138549088, states[0] = 12.295612, states[40]= 0.004900
Saving checkpoint... 
Iteration: 150724507, states[0] = -94.874523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162749681, states[0] = -94.911958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174703793, states[0] = -94.835544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186240300, states[0] = -94.898507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198421128, states[0] = -95.019642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210688472, states[0] = -94.801241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223049092, states[0] = 12.320754, states[40]= 0.004900
Saving checkpoint... 
Iteration: 235370195, states[0] = -95.003254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247590189, states[0] = -8.944164, states[40]= 0.002533
Saving checkpoint... 
Iteration: 259634965, states[0] = -51.268890, states[40]= 0.000024
Saving checkpoint... 
Iteration: 270684623, states[0] = -94.787691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282789103, states[0] = -94.953922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294736011, states[0] = -94.891655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306680064, states[0] = -94.754068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318749731, states[0] = -94.911067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330389208, states[0] = -95.010048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342046699, states[0] = 13.207294, states[40]= 0.004933
Saving checkpoint... 
Iteration: 353855177, states[0] = -94.996628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365726957, states[0] = -94.877244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377721048, states[0] = -94.867190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389619781, states[0] = -35.982413, states[40]= 0.000236
Saving checkpoint... 
Iteration: 401384051, states[0] = -95.008229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413365096, states[0] = -95.000946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425197645, states[0] = -94.822165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437166317, states[0] = -92.498670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447794956, states[0] = -94.958804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459684611, states[0] = -94.787464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471574576, states[0] = 1.378945, states[40]= 0.004375
Saving checkpoint... 
Iteration: 483260726, states[0] = -94.924683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495089558, states[0] = -8.425660, states[40]= 0.002643
Saving checkpoint... 
Iteration: 507093958, states[0] = -12.164515, states[40]= 0.001901
Saving checkpoint... 
Iteration: 519217999, states[0] = -94.861694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531347604, states[0] = -94.992882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543545030, states[0] = 13.815597, states[40]= 0.004964
Saving checkpoint... 
Iteration: 555702282, states[0] = -94.831633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567593861, states[0] = -12.078843, states[40]= 0.001917
Saving checkpoint... 
Iteration: 579369356, states[0] = -95.002581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591277278, states[0] = -94.942583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603337821, states[0] = -94.987746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615445681, states[0] = -95.024504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626150993, states[0] = -70.121941, states[40]= 0.000001
Saving checkpoint... 
Iteration: 638010906, states[0] = 22.495762, states[40]= 0.042213
Saving checkpoint... 
Iteration: 649879480, states[0] = -95.006420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661851534, states[0] = -94.994703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673581371, states[0] = -2.527537, states[40]= 0.003831
Saving checkpoint... 
Iteration: 685109918, states[0] = -26.789718, states[40]= 0.000641
Saving checkpoint... 
Iteration: 697288625, states[0] = -94.953187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709358229, states[0] = -94.997765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721539643, states[0] = 15.720887, states[40]= 0.005124
Saving checkpoint... 
Iteration: 733713112, states[0] = -94.852596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745685781, states[0] = -94.792030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754681697, states[0] = -94.769851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766727318, states[0] = -94.877559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778753024, states[0] = -94.915017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790757823, states[0] = -94.920991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801584292, states[0] = -4.462977, states[40]= 0.003473
Saving checkpoint... 
Iteration: 813443774, states[0] = -95.023988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825340974, states[0] = -94.989285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837364906, states[0] = -95.000573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849598576, states[0] = -16.340517, states[40]= 0.001292
Saving checkpoint... 
Iteration: 861753992, states[0] = -94.916190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873525030, states[0] = 20.077792, states[40]= 0.006798
Saving checkpoint... 
Iteration: 885609631, states[0] = -26.524892, states[40]= 0.000654
Saving checkpoint... 
Iteration: 897556514, states[0] = 9.476527, states[40]= 0.004830
Saving checkpoint... 
Iteration: 909625775, states[0] = -41.782090, states[40]= 0.000103
Saving checkpoint... 
Iteration: 921326501, states[0] = -94.981006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929956573, states[0] = -95.026331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941817519, states[0] = -94.975278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953746561, states[0] = -94.906362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965662195, states[0] = -88.298699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976393563, states[0] = -95.011021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988370959, states[0] = -95.002939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000416716, states[0] = -95.017679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012063110, states[0] = 6.768281, states[40]= 0.004751
Saving checkpoint... 
Iteration: 1023941349, states[0] = -95.023350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035214968, states[0] = -94.855828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047368578, states[0] = -95.001943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059117879, states[0] = -34.187573, states[40]= 0.000299
Saving checkpoint... 
Iteration: 1070999189, states[0] = -95.032493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082768859, states[0] = -94.933480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094776203, states[0] = -94.941156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106671373, states[0] = -94.274853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118708599, states[0] = -94.843746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130744363, states[0] = -94.903207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142750365, states[0] = -94.911321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153327795, states[0] = -94.981628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165465648, states[0] = -95.027719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177521107, states[0] = 20.920847, states[40]= 0.008471
Saving checkpoint... 
Iteration: 1189720129, states[0] = -94.865012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201894175, states[0] = -95.011061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213903870, states[0] = -95.014007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225957164, states[0] = -95.026232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237800225, states[0] = -94.962530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249947980, states[0] = -95.024515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262000756, states[0] = 43.328978, states[40]= 0.010904
Saving checkpoint... 
Iteration: 1274135477, states[0] = -51.811736, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1285975886, states[0] = -95.029235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297751044, states[0] = -94.912101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309637366, states[0] = -53.846128, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1321407831, states[0] = -95.015065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332354289, states[0] = -94.995537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344105915, states[0] = -23.102257, states[40]= 0.000810
Saving checkpoint... 
Iteration: 1355949682, states[0] = -95.024768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367885124, states[0] = -95.007935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378407819, states[0] = -95.015022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389221319, states[0] = -94.866957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400633942, states[0] = -50.176093, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1412693007, states[0] = -94.811411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424740940, states[0] = -94.898145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436563956, states[0] = 6.404854, states[40]= 0.004736
Saving checkpoint... 
Iteration: 1448665488, states[0] = -91.907167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460578433, states[0] = -0.747742, states[40]= 0.004111
Saving checkpoint... 
Iteration: 1472566198, states[0] = 5.419846, states[40]= 0.004690
Saving checkpoint... 
Iteration: 1484358067, states[0] = -94.997157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496043343, states[0] = 14.423103, states[40]= 0.005003
Saving checkpoint... 
Iteration: 1506698842, states[0] = -31.626756, states[40]= 0.000382
Saving checkpoint... 
Iteration: 1518362095, states[0] = 1.855482, states[40]= 0.004967
Saving checkpoint... 
Iteration: 1530062887, states[0] = 1.039554, states[40]= 0.004889
Saving checkpoint... 
Iteration: 1541870981, states[0] = -95.106074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553668003, states[0] = -95.268909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565194997, states[0] = -30.272058, states[40]= 0.000458
Saving checkpoint... 
Iteration: 1576903829, states[0] = -39.964931, states[40]= 0.000137
Saving checkpoint... 
Iteration: 1588745555, states[0] = -95.254856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600554220, states[0] = 5.622842, states[40]= 0.005372
Saving checkpoint... 
Iteration: 1612116818, states[0] = -95.217965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1623801339, states[0] = -95.191699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635684464, states[0] = -19.454630, states[40]= 0.001099
Saving checkpoint... 
Iteration: 1647544763, states[0] = -95.257483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659274590, states[0] = -95.287287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671115072, states[0] = -53.423646, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1678639040, states[0] = -89.654765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690661550, states[0] = -95.096079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1702801903, states[0] = 45.274856, states[40]= 0.073220
Saving checkpoint... 
Iteration: 1714880447, states[0] = -15.200856, states[40]= 0.001616
Saving checkpoint... 
Iteration: 1726853079, states[0] = 6.198579, states[40]= 0.005417
Saving checkpoint... 
Iteration: 1738762697, states[0] = -95.276931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750445638, states[0] = -95.258993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762349554, states[0] = -94.846848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774340618, states[0] = -91.482772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786419463, states[0] = -95.223916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1798225316, states[0] = 19.015988, states[40]= 0.007842
Saving checkpoint... 
Iteration: 1810182078, states[0] = -94.823797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821758696, states[0] = -94.956803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833461516, states[0] = -95.052053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845011381, states[0] = 22.282469, states[40]= 0.037678
Saving checkpoint... 
Iteration: 1855980726, states[0] = -95.042560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867040970, states[0] = 15.122917, states[40]= 0.005074
Saving checkpoint... 
Iteration: 1878420588, states[0] = -95.024684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890279524, states[0] = -94.948593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902146041, states[0] = -63.977091, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1914094282, states[0] = -12.573203, states[40]= 0.001831
Saving checkpoint... 
Iteration: 1925664787, states[0] = -91.428790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1937543142, states[0] = 14.477243, states[40]= 0.005008
Saving checkpoint... 
Iteration: 1949535033, states[0] = 17.242697, states[40]= 0.005374
Saving checkpoint... 
Iteration: 1961352531, states[0] = -94.994788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1973091175, states[0] = -9.780189, states[40]= 0.002360
Saving checkpoint... 
Iteration: 1984694852, states[0] = -94.815334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1996596155, states[0] = -14.141373, states[40]= 0.001579
Saving checkpoint... 
Iteration: 2008754904, states[0] = -94.916622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020648662, states[0] = -66.977484, states[40]= 0.000002
Saving checkpoint... 
Iteration: 2031352557, states[0] = -94.994252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2043077953, states[0] = -0.472454, states[40]= 0.004149
Saving checkpoint... 
Iteration: 2054879344, states[0] = -95.005373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066297345, states[0] = -94.959612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2078095444, states[0] = -13.489736, states[40]= 0.001678
Saving checkpoint... 
Iteration: 2089277365, states[0] = -94.941581, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.907702
 - CaMKt in component CaMK (millimolar): 0.007163
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.557802
 - nass in component intracellular_ions (millimolar): 6.557862
 - ki in component intracellular_ions (millimolar): 145.417216
 - kss in component intracellular_ions (millimolar): 145.417197
 - cansr in component intracellular_ions (millimolar): 1.321267
 - cajsr in component intracellular_ions (millimolar): 1.282830
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880102
 - hs in component INa (dimensionless): 0.880098
 - j in component INa (dimensionless): 0.880068
 - hsp in component INa (dimensionless): 0.726021
 - jp in component INa (dimensionless): 0.880048
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709402
 - hLp in component INaL (dimensionless): 0.450203
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.618468
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.692923
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934050
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001635
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330206
 - xs1 in component IKs (dimensionless): 0.245326
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997336
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:15:12 (23204): called boinc_finish(0)

</stderr_txt>
]]>


CoMBA Research Group Logo
University San Jorge Logo

©2024 Universidad San Jorge