𝕏

Task 55889226

Name HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377_0
Workunit 26540606
Created 3 Jul 2024, 10:02:26 UTC
Sent 3 Jul 2024, 11:45:23 UTC
Report deadline 6 Jul 2024, 11:45:23 UTC
Received 5 Jul 2024, 11:53:14 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241775
Run time 1 hours 9 min 22 sec
CPU time 1 hours 7 min 39 sec
Validate state Valid
Credit 43.44
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.74 MB
Peak swap size 6.27 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377_0_r781728554_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377_0_r781728554_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.999785
     * GNaL_b in INaL: 0.005568
     * Gto_b in Ito: 0.083066
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031801
     * GKs_b in IKs: 0.001894
     * GK1_b in IK1: 0.162768
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.821232
     * GKb_b in IKb: 0.003832
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030344
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 23913960, states[0] = -94.176785, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377_0_r781728554_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377_0_r781728554_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.999785
     * GNaL_b in INaL: 0.005568
     * Gto_b in Ito: 0.083066
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031801
     * GKs_b in IKs: 0.001894
     * GK1_b in IK1: 0.162768
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.821232
     * GKb_b in IKb: 0.003832
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030344
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 23913960
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.176785 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 38710819, states[0] = -94.206765, states[40]= 0.000001
Saving checkpoint... 
Iteration: 62771300, states[0] = -94.229698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 87702766, states[0] = -94.219935, states[40]= 0.000001
Saving checkpoint... 
Iteration: 111650490, states[0] = -94.228424, states[40]= 0.000001
Saving checkpoint... 
Iteration: 133745935, states[0] = -94.230359, states[40]= 0.000001
Saving checkpoint... 
Iteration: 157807394, states[0] = -94.231492, states[40]= 0.000001
Saving checkpoint... 
Iteration: 183015747, states[0] = -94.254439, states[40]= 0.000001
Saving checkpoint... 
Iteration: 207966344, states[0] = -94.230629, states[40]= 0.000001
Saving checkpoint... 
Iteration: 232025973, states[0] = 33.836123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256884403, states[0] = -94.258306, states[40]= 0.000001
Saving checkpoint... 
Iteration: 281469093, states[0] = -94.240045, states[40]= 0.000001
Saving checkpoint... 
Iteration: 305484713, states[0] = -94.239401, states[40]= 0.000001
Saving checkpoint... 
Iteration: 329404986, states[0] = -94.241303, states[40]= 0.000001
Saving checkpoint... 
Iteration: 354487741, states[0] = -94.178100, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377_0_r781728554_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377_0_r781728554_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.999785
     * GNaL_b in INaL: 0.005568
     * Gto_b in Ito: 0.083066
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031801
     * GKs_b in IKs: 0.001894
     * GK1_b in IK1: 0.162768
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.821232
     * GKb_b in IKb: 0.003832
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030344
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 354487741
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.178100 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 377001736, states[0] = -94.254053, states[40]= 0.000001
Saving checkpoint... 
Iteration: 402086781, states[0] = 20.295330, states[40]= 0.000003
Saving checkpoint... 
Iteration: 425855890, states[0] = -94.230405, states[40]= 0.000001
Saving checkpoint... 
Iteration: 448298102, states[0] = -93.700823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470632153, states[0] = -94.241704, states[40]= 0.000001
Saving checkpoint... 
Iteration: 496231102, states[0] = -44.305597, states[40]= 0.001300
Saving checkpoint... 
Iteration: 521607657, states[0] = -94.233917, states[40]= 0.000001
Saving checkpoint... 
Iteration: 546484130, states[0] = -94.172729, states[40]= 0.000001
Saving checkpoint... 
Iteration: 571892472, states[0] = -94.228087, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377_0_r781728554_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377_0_r781728554_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.999785
     * GNaL_b in INaL: 0.005568
     * Gto_b in Ito: 0.083066
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031801
     * GKs_b in IKs: 0.001894
     * GK1_b in IK1: 0.162768
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.821232
     * GKb_b in IKb: 0.003832
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030344
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 571892472
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.228087 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 585984264, states[0] = -94.226636, states[40]= 0.000001
Saving checkpoint... 
Iteration: 601675687, states[0] = -94.231513, states[40]= 0.000001
Saving checkpoint... 
Iteration: 624272154, states[0] = -86.399325, states[40]= 0.000003
Saving checkpoint... 
Iteration: 638677961, states[0] = -94.247003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 662362479, states[0] = -93.966916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686967057, states[0] = -94.251402, states[40]= 0.000001
Saving checkpoint... 
Iteration: 712563260, states[0] = -94.218612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 737946227, states[0] = -94.225318, states[40]= 0.000001
Saving checkpoint... 
Iteration: 763016556, states[0] = -94.248939, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377_0_r781728554_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377_0_r781728554_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.999785
     * GNaL_b in INaL: 0.005568
     * Gto_b in Ito: 0.083066
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031801
     * GKs_b in IKs: 0.001894
     * GK1_b in IK1: 0.162768
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.821232
     * GKb_b in IKb: 0.003832
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030344
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 763016556
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.248939 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 777264434, states[0] = -94.240246, states[40]= 0.000001
Saving checkpoint... 
Iteration: 802209059, states[0] = -30.956246, states[40]= 0.005169
Saving checkpoint... 
Iteration: 817832119, states[0] = -94.226067, states[40]= 0.000001
Saving checkpoint... 
Iteration: 842646823, states[0] = -94.239982, states[40]= 0.000001
Saving checkpoint... 
Iteration: 865965705, states[0] = -94.223511, states[40]= 0.000001
Saving checkpoint... 
Iteration: 890690082, states[0] = -94.245356, states[40]= 0.000001
Saving checkpoint... 
Iteration: 915561916, states[0] = -94.230216, states[40]= 0.000001
Saving checkpoint... 
Iteration: 940560684, states[0] = -94.214812, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377_0_r781728554_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_MID_4000-conf_377_0_r781728554_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.999785
     * GNaL_b in INaL: 0.005568
     * Gto_b in Ito: 0.083066
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031801
     * GKs_b in IKs: 0.001894
     * GK1_b in IK1: 0.162768
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.821232
     * GKb_b in IKb: 0.003832
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030344
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 940560684
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.214812 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 954024782, states[0] = 33.726987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976798441, states[0] = -94.250099, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1000011700, states[0] = 30.240676, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1022587722, states[0] = -94.223663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1038108177, states[0] = 12.317363, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1053211387, states[0] = -94.238694, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1078205882, states[0] = -29.482477, states[40]= 0.005602
Saving checkpoint... 
Iteration: 1102857958, states[0] = -94.248688, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1118958268, states[0] = -94.246460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1143164786, states[0] = -94.239218, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1167163361, states[0] = -94.238980, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1189986770, states[0] = -94.219326, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1213809852, states[0] = -94.221661, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1237780218, states[0] = -94.221882, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1262377107, states[0] = -93.999459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287186214, states[0] = -94.236745, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1312072965, states[0] = 25.197115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1332837417, states[0] = -94.246042, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1356801206, states[0] = -94.245570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1381114465, states[0] = -94.238124, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1405583703, states[0] = -94.223811, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1429937297, states[0] = -94.217104, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1454121415, states[0] = 7.328870, states[40]= 0.000087
Saving checkpoint... 
Iteration: 1478585717, states[0] = -94.217525, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1487749057, states[0] = -94.219430, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.091393
 - CaMKt in component CaMK (millimolar): 0.002634
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 7.861820
 - nass in component intracellular_ions (millimolar): 7.861978
 - ki in component intracellular_ions (millimolar): 143.918783
 - kss in component intracellular_ions (millimolar): 143.918767
 - cansr in component intracellular_ions (millimolar): 1.847173
 - cajsr in component intracellular_ions (millimolar): 1.848983
 - cai in component intracellular_ions (millimolar): 0.000102
 - m in component INa (dimensionless): 0.003927
 - hf in component INa (dimensionless): 0.865210
 - hs in component INa (dimensionless): 0.865211
 - j in component INa (dimensionless): 0.865214
 - hsp in component INa (dimensionless): 0.698578
 - jp in component INa (dimensionless): 0.865215
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707306
 - hLp in component INaL (dimensionless): 0.512723
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.990088
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.995935
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.994754
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004605
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.009149
 - xs1 in component IKs (dimensionless): 0.054241
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997542
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
13:52:56 (15004): called boinc_finish(0)

</stderr_txt>
]]>