𝕏

Task 55887728

Name HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_EPI_6000-conf_274_0
Workunit 26539858
Created 3 Jul 2024, 10:01:24 UTC
Sent 3 Jul 2024, 11:39:01 UTC
Report deadline 6 Jul 2024, 11:39:01 UTC
Received 4 Jul 2024, 3:11:43 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241612
Run time 2 hours 59 min 42 sec
CPU time 2 hours 55 min 52 sec
Validate state Valid
Credit 43.61
Device peak FLOPS 3.27 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_EPI_6000-conf_274.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_EPI_6000-conf_274_0_r424807614_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Drouin_EPI_6000-conf_274_0_r424807614_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.761355
     * GNaL_b in INaL: 0.005976
     * Gto_b in Ito: 0.083290
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031496
     * GKs_b in IKs: 0.001932
     * GK1_b in IK1: 0.167794
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.328552
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035194
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8331863, states[0] = -94.391900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16714969, states[0] = -94.329296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25620973, states[0] = -94.293616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34336542, states[0] = -94.280265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43037259, states[0] = -94.280112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51850403, states[0] = -94.283460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60706997, states[0] = -94.286552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69434877, states[0] = -94.242024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78168802, states[0] = -61.898778, states[40]= 0.000020
Saving checkpoint... 
Iteration: 86846258, states[0] = -94.250517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95625310, states[0] = -94.253217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104003912, states[0] = -94.260025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112653709, states[0] = -94.266478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121299165, states[0] = -94.275623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129596890, states[0] = -94.293095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138228506, states[0] = -93.759708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147256088, states[0] = -93.908741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156205727, states[0] = -93.600763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164872829, states[0] = -94.257717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173714405, states[0] = -94.258763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182729360, states[0] = -94.258840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191456068, states[0] = -94.260724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200068670, states[0] = -94.264412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208769323, states[0] = -94.268549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217408297, states[0] = -94.275862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226090131, states[0] = -94.285505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234725583, states[0] = -94.298164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243275964, states[0] = -93.991607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252408312, states[0] = -94.234819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261164518, states[0] = -58.190425, states[40]= 0.000034
Saving checkpoint... 
Iteration: 269906101, states[0] = -94.258032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278431506, states[0] = -94.260845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287304762, states[0] = -94.261836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296053064, states[0] = -94.264344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304795424, states[0] = -94.267782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313609589, states[0] = -94.270979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322447476, states[0] = -94.274413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331199840, states[0] = -94.281214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339989822, states[0] = -94.288638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348665505, states[0] = -94.297599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357392435, states[0] = -94.220495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366209298, states[0] = -93.631182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375233226, states[0] = -93.789387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384019445, states[0] = 24.685289, states[40]= -0.000000
Saving checkpoint... 
Iteration: 392644145, states[0] = -94.258566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401225684, states[0] = -94.261739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409863749, states[0] = -94.265974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418862593, states[0] = -94.265922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427375198, states[0] = -94.275421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436185456, states[0] = -94.280887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445245449, states[0] = -94.278931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453890205, states[0] = -94.291660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462453391, states[0] = -94.261148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470934592, states[0] = -94.256435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479552275, states[0] = -94.258490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488214396, states[0] = -94.261181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497134204, states[0] = -94.261931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505813934, states[0] = -94.265980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514510394, states[0] = -94.271516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523149496, states[0] = -94.281412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531694883, states[0] = -94.296359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540589561, states[0] = -94.292725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549708863, states[0] = -94.296146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558686182, states[0] = -94.296154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567266449, states[0] = -93.952646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575744237, states[0] = -94.256578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584247684, states[0] = -94.260123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592972792, states[0] = -94.263081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601538414, states[0] = -94.270240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610116983, states[0] = -94.281864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618840759, states[0] = -94.292242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627376529, states[0] = -94.202098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635944642, states[0] = -94.255120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644489851, states[0] = -94.257657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653287901, states[0] = -94.259221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661861230, states[0] = -94.264073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670790746, states[0] = -94.265072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679380999, states[0] = -94.273334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687962604, states[0] = -94.287038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696512422, states[0] = -94.279746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705278235, states[0] = -93.996307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713766358, states[0] = -94.255396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722394562, states[0] = -94.257784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731081203, states[0] = -94.260714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739824769, states[0] = -94.264016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748178131, states[0] = -94.278731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756099228, states[0] = 5.652254, states[40]= 0.000077
Saving checkpoint... 
Iteration: 764808678, states[0] = -94.254781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773329942, states[0] = -94.257929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782024770, states[0] = -94.260982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790565778, states[0] = -94.268216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799377529, states[0] = -94.272503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807994638, states[0] = -94.284872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816579198, states[0] = -94.289654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825180573, states[0] = -80.354702, states[40]= 0.000002
Saving checkpoint... 
Iteration: 833939677, states[0] = -94.253619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842740633, states[0] = -94.254544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851248738, states[0] = -94.258060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859843927, states[0] = -94.262806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868622010, states[0] = -94.266496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877434089, states[0] = -94.270488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885931189, states[0] = -94.286750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894525654, states[0] = -94.281164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903241130, states[0] = -93.830099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911881279, states[0] = -94.253290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920643010, states[0] = -94.254513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929485945, states[0] = -94.255494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938188844, states[0] = -94.257973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946984086, states[0] = -94.260216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955513767, states[0] = -94.268053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964238455, states[0] = -94.275158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973056126, states[0] = -94.281274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981351529, states[0] = -94.166971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990212085, states[0] = -93.646878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998916631, states[0] = -94.252454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007574908, states[0] = -94.254277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016243155, states[0] = -94.256842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024800582, states[0] = -94.262196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033528295, states[0] = -94.267137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042167395, states[0] = -94.276827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051116705, states[0] = -94.278488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059816198, states[0] = -94.289715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068608112, states[0] = -94.290039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077711556, states[0] = -94.292074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086557171, states[0] = -94.285001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095221030, states[0] = -93.707363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103800167, states[0] = -94.252216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112462892, states[0] = -94.254255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121327061, states[0] = -94.255276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130267253, states[0] = -94.255740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138976571, states[0] = -94.258834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147652850, states[0] = -94.263768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156441233, states[0] = -94.268172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165213681, states[0] = -94.274384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174199051, states[0] = -94.274780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182867483, states[0] = -94.286933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191486651, states[0] = -94.268711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200133512, states[0] = -23.639575, states[40]= 0.000354
Saving checkpoint... 
Iteration: 1208960886, states[0] = -94.250639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217671079, states[0] = -94.252057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226307670, states[0] = -94.254637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235027714, states[0] = -94.257462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243577634, states[0] = -94.264491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252349550, states[0] = -94.269759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261336619, states[0] = -94.270039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270157632, states[0] = -94.275403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279022802, states[0] = -94.280177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287855788, states[0] = -94.286564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297074386, states[0] = -94.278115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306011179, states[0] = -94.280413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314741241, states[0] = -94.289821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323450619, states[0] = -94.253199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332222533, states[0] = -93.715327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340817152, states[0] = -94.250305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349047839, states[0] = -94.256346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357763273, states[0] = -94.260232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366455295, states[0] = -94.266224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375112274, states[0] = -94.276157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383618737, states[0] = -94.288226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392204681, states[0] = -93.582584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401025280, states[0] = 25.948726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409740340, states[0] = -94.250182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418152005, states[0] = -94.254659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426638925, states[0] = -94.261884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435201561, states[0] = -94.272696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443834055, states[0] = -94.286154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452347111, states[0] = -94.156582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460861551, states[0] = -94.249159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469340492, states[0] = -94.252484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478040343, states[0] = -94.255442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486587877, states[0] = -94.262416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495108264, states[0] = -94.275376, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.124210
 - CaMKt in component CaMK (millimolar): 0.001356
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 7.049494
 - nass in component intracellular_ions (millimolar): 7.049628
 - ki in component intracellular_ions (millimolar): 144.668670
 - kss in component intracellular_ions (millimolar): 144.668657
 - cansr in component intracellular_ions (millimolar): 2.369139
 - cajsr in component intracellular_ions (millimolar): 2.369405
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003914
 - hf in component INa (dimensionless): 0.865837
 - hs in component INa (dimensionless): 0.865838
 - j in component INa (dimensionless): 0.865839
 - hsp in component INa (dimensionless): 0.699710
 - jp in component INa (dimensionless): 0.865839
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708184
 - hLp in component INaL (dimensionless): 0.514668
 - a in component Ito (dimensionless): 0.000657
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.999851
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.999851
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999554
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005197
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000469
 - xs1 in component IKs (dimensionless): 0.014239
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997534
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:50:57 (16903): called boinc_finish(0)

</stderr_txt>
]]>


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