𝕏

Task 55883314

Name HuVeMOp_20240703115557113738_ORdGradInc_k_26-Pueyo_APDR-conf_336_0
Workunit 26537658
Created 3 Jul 2024, 9:57:43 UTC
Sent 3 Jul 2024, 11:06:31 UTC
Report deadline 6 Jul 2024, 20:42:31 UTC
Received 4 Jul 2024, 7:18:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231066
Run time 1 hours 47 min 45 sec
CPU time 1 hours 30 min 48 sec
Validate state Valid
Credit 63.99
Device peak FLOPS 4.29 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 5.22 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Pueyo_APDR-conf_336.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Pueyo_APDR-conf_336_0_r2066112996_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Pueyo_APDR-conf_336_0_r2066112996_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.098548
     * GNaL_b in INaL: 0.005774
     * Gto_b in Ito: 0.081921
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031943
     * GKs_b in IKs: 0.001967
     * GK1_b in IK1: 0.162250
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.753973
     * GKb_b in IKb: 0.003831
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035002
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7988948, states[0] = -95.114095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20134877, states[0] = -60.522125, states[40]= 0.000004
Saving checkpoint... 
Iteration: 31202885, states[0] = -94.865156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43184206, states[0] = -94.809577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54931518, states[0] = -95.020386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66926177, states[0] = -95.012638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78893774, states[0] = -94.999541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91025960, states[0] = 19.721595, states[40]= 0.007021
Saving checkpoint... 
Iteration: 102985322, states[0] = -95.013073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114811980, states[0] = -94.954631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126644110, states[0] = -66.753861, states[40]= 0.000002
Saving checkpoint... 
Iteration: 138677612, states[0] = -94.746950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150461581, states[0] = -95.005732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162733304, states[0] = -94.870767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174572902, states[0] = 0.969899, states[40]= 0.004393
Saving checkpoint... 
Iteration: 186486677, states[0] = -95.008531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198044302, states[0] = 13.560990, states[40]= 0.005170
Saving checkpoint... 
Iteration: 208500243, states[0] = -65.127776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220465950, states[0] = -95.005291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232407115, states[0] = -94.992960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244237821, states[0] = -94.876511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256354621, states[0] = -94.974482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268356503, states[0] = -94.975289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280267203, states[0] = -94.912788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292338299, states[0] = -94.966557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304221242, states[0] = -94.850662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316112687, states[0] = -32.696469, states[40]= 0.000340
Saving checkpoint... 
Iteration: 327973527, states[0] = -95.006217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339993371, states[0] = -95.008841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351961047, states[0] = -95.004270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363891270, states[0] = -94.988138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376176958, states[0] = -94.737983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387163521, states[0] = -93.117098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399502730, states[0] = 39.548021, states[40]= 0.119388
Saving checkpoint... 
Iteration: 411726614, states[0] = -94.859377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420065621, states[0] = 4.665184, states[40]= 0.004727
Saving checkpoint... 
Iteration: 432113256, states[0] = -33.244748, states[40]= 0.000319
Saving checkpoint... 
Iteration: 444333165, states[0] = -94.963703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456566991, states[0] = 4.012525, states[40]= 0.004681
Saving checkpoint... 
Iteration: 467918546, states[0] = -94.995645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479898452, states[0] = -94.990250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491906157, states[0] = -94.992429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503567914, states[0] = 3.563814, states[40]= 0.004647
Saving checkpoint... 
Iteration: 515474308, states[0] = -95.006210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527129818, states[0] = -50.089544, states[40]= 0.000027
Saving checkpoint... 
Iteration: 539225340, states[0] = -94.857253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551339773, states[0] = -94.967143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562507933, states[0] = 24.541154, states[40]= 0.085168
Saving checkpoint... 
Iteration: 574351777, states[0] = -94.972950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586237096, states[0] = -94.875180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598478786, states[0] = -95.006793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610518963, states[0] = 21.495511, states[40]= 0.011038
Saving checkpoint... 
Iteration: 622515416, states[0] = 22.186079, states[40]= 0.017674
Saving checkpoint... 
Iteration: 634410990, states[0] = -94.993636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646632289, states[0] = -52.777406, states[40]= 0.000017
Saving checkpoint... 
Iteration: 658750030, states[0] = -94.892614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671050101, states[0] = 11.305781, states[40]= 0.005031
Saving checkpoint... 
Iteration: 682945994, states[0] = -95.001417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695136733, states[0] = -57.713737, states[40]= 0.000007
Saving checkpoint... 
Iteration: 706552020, states[0] = 10.537779, states[40]= 0.004998
Saving checkpoint... 
Iteration: 716499354, states[0] = -95.009309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726323769, states[0] = -94.958143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735591913, states[0] = -12.917981, states[40]= 0.001792
Saving checkpoint... 
Iteration: 742052477, states[0] = 10.353251, states[40]= 0.004990
Saving checkpoint... 
Iteration: 751991245, states[0] = -95.008328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761754090, states[0] = -94.897580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771612722, states[0] = -32.729365, states[40]= 0.000339
Saving checkpoint... 
Iteration: 782500308, states[0] = -57.059783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794723666, states[0] = -94.854372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806393512, states[0] = -94.988566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818274420, states[0] = -94.919812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830168834, states[0] = -94.419717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842070430, states[0] = 2.299125, states[40]= 0.004535
Saving checkpoint... 
Iteration: 854111197, states[0] = -31.261832, states[40]= 0.000402
Saving checkpoint... 
Iteration: 866802913, states[0] = -94.944153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879186539, states[0] = -94.782467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891613189, states[0] = -33.179786, states[40]= 0.000321
Saving checkpoint... 
Iteration: 903911037, states[0] = -94.993485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915308210, states[0] = -94.947932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927326686, states[0] = -94.959748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939254595, states[0] = -94.898084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951364104, states[0] = -94.978041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963558491, states[0] = 7.855543, states[40]= 0.004894
Saving checkpoint... 
Iteration: 975413915, states[0] = -94.994184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987272623, states[0] = -94.917922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999080642, states[0] = -3.737417, states[40]= 0.003659
Saving checkpoint... 
Iteration: 1011261508, states[0] = -94.906095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023281137, states[0] = -94.926082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035308304, states[0] = -94.947925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047072509, states[0] = 1.201109, states[40]= 0.004419
Saving checkpoint... 
Iteration: 1059254851, states[0] = -94.898319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070840316, states[0] = -94.967107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081216822, states[0] = -94.842607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091889282, states[0] = -94.987064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103514635, states[0] = 22.331791, states[40]= 0.020186
Saving checkpoint... 
Iteration: 1115262320, states[0] = -94.906941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127255626, states[0] = -94.899207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139056628, states[0] = 8.644499, states[40]= 0.004925
Saving checkpoint... 
Iteration: 1150736956, states[0] = -94.874635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162543177, states[0] = 13.994397, states[40]= 0.005207
Saving checkpoint... 
Iteration: 1173432244, states[0] = -94.998352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185604512, states[0] = -24.869026, states[40]= 0.000704
Saving checkpoint... 
Iteration: 1197605211, states[0] = -25.535556, states[40]= 0.000672
Saving checkpoint... 
Iteration: 1209413926, states[0] = -94.994045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221328199, states[0] = -94.960446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233561771, states[0] = 6.425844, states[40]= 0.004829
Saving checkpoint... 
Iteration: 1245715344, states[0] = -94.839909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257644479, states[0] = -66.994954, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1268520420, states[0] = 21.182682, states[40]= 0.009638
Saving checkpoint... 
Iteration: 1280281063, states[0] = -94.925858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292330318, states[0] = -94.961608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304378294, states[0] = -94.983225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316260213, states[0] = -94.904444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328385784, states[0] = -94.985781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340461983, states[0] = -95.003821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353030598, states[0] = 18.423413, states[40]= 0.006145
Saving checkpoint... 
Iteration: 1361318164, states[0] = -94.954298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373607242, states[0] = -27.473871, states[40]= 0.000580
Saving checkpoint... 
Iteration: 1385742787, states[0] = -94.882666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398036845, states[0] = 16.323527, states[40]= 0.005528
Saving checkpoint... 
Iteration: 1410163927, states[0] = -93.296396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422373255, states[0] = -94.981319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434383396, states[0] = -94.984917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445549893, states[0] = 11.388540, states[40]= 0.005035
Saving checkpoint... 
Iteration: 1457332458, states[0] = -94.962701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469308553, states[0] = -94.947836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481315687, states[0] = -94.952635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493440219, states[0] = -94.999807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504918054, states[0] = -56.573017, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1516703230, states[0] = -95.144015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1528444167, states[0] = -95.214351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540267013, states[0] = -3.348327, states[40]= 0.004185
Saving checkpoint... 
Iteration: 1552114833, states[0] = -95.190666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564119097, states[0] = -95.201802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1575938456, states[0] = 13.252472, states[40]= 0.006258
Saving checkpoint... 
Iteration: 1587661254, states[0] = 0.429169, states[40]= 0.004872
Saving checkpoint... 
Iteration: 1599344512, states[0] = 10.162999, states[40]= 0.005872
Saving checkpoint... 
Iteration: 1611298093, states[0] = -95.288344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621974630, states[0] = -95.124607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633700613, states[0] = -95.179823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645511210, states[0] = 23.666795, states[40]= 0.041362
Saving checkpoint... 
Iteration: 1657229496, states[0] = 17.266738, states[40]= 0.007314
Saving checkpoint... 
Iteration: 1669089995, states[0] = -95.159874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1680912751, states[0] = 23.119076, states[40]= 0.030481
Saving checkpoint... 
Iteration: 1692951706, states[0] = 6.220157, states[40]= 0.005517
Saving checkpoint... 
Iteration: 1704889830, states[0] = -95.284772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717015188, states[0] = -57.255099, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1728766499, states[0] = -95.105478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1740569405, states[0] = -95.269047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752473451, states[0] = -95.123128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1764371163, states[0] = -7.727422, states[40]= 0.003188
Saving checkpoint... 
Iteration: 1776055109, states[0] = 4.238290, states[40]= 0.005334
Saving checkpoint... 
Iteration: 1788032982, states[0] = 15.733639, states[40]= 0.006793
Saving checkpoint... 
Iteration: 1798959431, states[0] = -95.083452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1811060320, states[0] = 6.004249, states[40]= 0.004885
Saving checkpoint... 
Iteration: 1822918208, states[0] = -95.030231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834886985, states[0] = -95.011046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846794250, states[0] = -94.954717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858816534, states[0] = -94.965392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870791850, states[0] = -94.943637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882886933, states[0] = -94.991853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894992803, states[0] = -95.012020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907206601, states[0] = -94.826457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919321706, states[0] = -94.958198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927604965, states[0] = -25.394912, states[40]= 0.000679
Saving checkpoint... 
Iteration: 1939600323, states[0] = -20.939150, states[40]= 0.000905
Saving checkpoint... 
Iteration: 1951651635, states[0] = -77.634905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963612802, states[0] = -32.839909, states[40]= 0.000335
Saving checkpoint... 
Iteration: 1974258774, states[0] = -94.902757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1986081505, states[0] = -4.349022, states[40]= 0.003540
Saving checkpoint... 
Iteration: 1998048158, states[0] = 12.069733, states[40]= 0.005069
Saving checkpoint... 
Iteration: 2010071411, states[0] = 1.784043, states[40]= 0.004483
Saving checkpoint... 
Iteration: 2022134316, states[0] = -55.016845, states[40]= 0.000012
Saving checkpoint... 
Iteration: 2034042403, states[0] = 14.286241, states[40]= 0.005236
Saving checkpoint... 
Iteration: 2046027261, states[0] = 19.431849, states[40]= 0.006721
Saving checkpoint... 
Iteration: 2058138576, states[0] = -59.817984, states[40]= 0.000005
Saving checkpoint... 
Iteration: 2070127495, states[0] = -47.598307, states[40]= 0.000040
Saving checkpoint... 
Iteration: 2081914155, states[0] = -94.993540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093625348, states[0] = -45.329973, states[40]= 0.000057
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.884380
 - CaMKt in component CaMK (millimolar): 0.006858
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.573340
 - nass in component intracellular_ions (millimolar): 6.573399
 - ki in component intracellular_ions (millimolar): 145.405872
 - kss in component intracellular_ions (millimolar): 145.405853
 - cansr in component intracellular_ions (millimolar): 1.305948
 - cajsr in component intracellular_ions (millimolar): 1.268258
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003625
 - hf in component INa (dimensionless): 0.879697
 - hs in component INa (dimensionless): 0.879693
 - j in component INa (dimensionless): 0.879664
 - hsp in component INa (dimensionless): 0.725259
 - jp in component INa (dimensionless): 0.879645
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709786
 - hLp in component INaL (dimensionless): 0.452454
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.622567
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.697633
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936121
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001581
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332282
 - xs1 in component IKs (dimensionless): 0.239065
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997342
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:33:43 (17372): called boinc_finish(0)

</stderr_txt>
]]>


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