𝕏

Task 55882481

Name HuVeMOp_20240703115557113738_ORdGradInc_k_26-Pueyo_APDR-conf_125_1
Workunit 26537241
Created 3 Jul 2024, 9:57:07 UTC
Sent 3 Jul 2024, 11:00:29 UTC
Report deadline 6 Jul 2024, 20:36:29 UTC
Received 3 Jul 2024, 23:06:14 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231681
Run time 1 hours 34 min 19 sec
CPU time 1 hours 17 min 48 sec
Validate state Valid
Credit 71.19
Device peak FLOPS 5.60 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.99 MB
Peak swap size 32.57 GB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Pueyo_APDR-conf_125.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Pueyo_APDR-conf_125_1_r1026984871_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Pueyo_APDR-conf_125_1_r1026984871_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.909344
     * GNaL_b in INaL: 0.005495
     * Gto_b in Ito: 0.081656
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032229
     * GKs_b in IKs: 0.001881
     * GK1_b in IK1: 0.166450
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.936193
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030144
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 2680163, states[0] = -94.976245, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Pueyo_APDR-conf_125.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Pueyo_APDR-conf_125_1_r1026984871_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Pueyo_APDR-conf_125_1_r1026984871_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.909344
     * GNaL_b in INaL: 0.005495
     * Gto_b in Ito: 0.081656
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032229
     * GKs_b in IKs: 0.001881
     * GK1_b in IK1: 0.166450
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.936193
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030144
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 2680163
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.976245 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 24226682, states[0] = -94.966941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45847988, states[0] = -95.045188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68144803, states[0] = -71.270737, states[40]= 0.000001
Saving checkpoint... 
Iteration: 90698008, states[0] = -94.863242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113150522, states[0] = -79.297499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134562987, states[0] = 5.552381, states[40]= 0.004800
Saving checkpoint... 
Iteration: 157034695, states[0] = 16.916567, states[40]= 0.005722
Saving checkpoint... 
Iteration: 179397936, states[0] = -95.036099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201738360, states[0] = -94.924625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224069359, states[0] = 2.502550, states[40]= 0.004570
Saving checkpoint... 
Iteration: 246548255, states[0] = 11.834885, states[40]= 0.005084
Saving checkpoint... 
Iteration: 268968920, states[0] = -95.050752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291516583, states[0] = 21.906371, states[40]= 0.014863
Saving checkpoint... 
Iteration: 313937272, states[0] = -95.045130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336646031, states[0] = -71.506316, states[40]= 0.000001
Saving checkpoint... 
Iteration: 358884907, states[0] = -95.031413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381341303, states[0] = -95.013599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403643895, states[0] = -68.449387, states[40]= 0.000001
Saving checkpoint... 
Iteration: 426027144, states[0] = 19.354113, states[40]= 0.006784
Saving checkpoint... 
Iteration: 448508749, states[0] = 24.021367, states[40]= 0.070988
Saving checkpoint... 
Iteration: 471023678, states[0] = 20.309329, states[40]= 0.007821
Saving checkpoint... 
Iteration: 493571322, states[0] = 1.472705, states[40]= 0.004465
Saving checkpoint... 
Iteration: 516163439, states[0] = -93.919679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538873013, states[0] = -95.027150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561175855, states[0] = -94.792878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583265970, states[0] = -94.957769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605008046, states[0] = 24.477825, states[40]= 0.083225
Saving checkpoint... 
Iteration: 627308982, states[0] = -94.994513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649968521, states[0] = -95.050424, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Pueyo_APDR-conf_125.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Pueyo_APDR-conf_125_1_r1026984871_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Pueyo_APDR-conf_125_1_r1026984871_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.909344
     * GNaL_b in INaL: 0.005495
     * Gto_b in Ito: 0.081656
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032229
     * GKs_b in IKs: 0.001881
     * GK1_b in IK1: 0.166450
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.936193
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030144
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 649968521
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.050424 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 671234466, states[0] = -94.918507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692113824, states[0] = -34.965027, states[40]= 0.000253
Saving checkpoint... 
Iteration: 713897207, states[0] = -95.035032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734601420, states[0] = -22.889307, states[40]= 0.000794
Saving checkpoint... 
Iteration: 756633000, states[0] = -55.186119, states[40]= 0.000011
Saving checkpoint... 
Iteration: 778782726, states[0] = -94.973899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800872795, states[0] = -95.026912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822981520, states[0] = -95.052178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845218408, states[0] = -94.893128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867602295, states[0] = -23.736141, states[40]= 0.000751
Saving checkpoint... 
Iteration: 889839502, states[0] = -95.012386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911788913, states[0] = -94.979153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933787533, states[0] = -94.977978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955792375, states[0] = -94.981969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977503112, states[0] = 37.117711, states[40]= 0.131967
Saving checkpoint... 
Iteration: 999576883, states[0] = -1.754308, states[40]= 0.004025
Saving checkpoint... 
Iteration: 1019736970, states[0] = -94.921891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041752531, states[0] = -94.942292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063081254, states[0] = -4.704794, states[40]= 0.003481
Saving checkpoint... 
Iteration: 1084410767, states[0] = -95.038558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106489373, states[0] = -95.053025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128361355, states[0] = -95.022249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149980913, states[0] = -95.051900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171906559, states[0] = -95.037392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193518863, states[0] = 21.442823, states[40]= 0.011218
Saving checkpoint... 
Iteration: 1215120185, states[0] = -41.352544, states[40]= 0.000103
Saving checkpoint... 
Iteration: 1236952311, states[0] = -95.047414, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Pueyo_APDR-conf_125.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Pueyo_APDR-conf_125_1_r1026984871_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-Pueyo_APDR-conf_125_1_r1026984871_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.909344
     * GNaL_b in INaL: 0.005495
     * Gto_b in Ito: 0.081656
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032229
     * GKs_b in IKs: 0.001881
     * GK1_b in IK1: 0.166450
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.936193
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030144
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1236952311
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.047414 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1263805602, states[0] = -94.991779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290595639, states[0] = -17.294717, states[40]= 0.001198
Saving checkpoint... 
Iteration: 1314531782, states[0] = 17.914308, states[40]= 0.006024
Saving checkpoint... 
Iteration: 1336885525, states[0] = -95.031026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358758381, states[0] = -94.948975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380580155, states[0] = -3.922085, states[40]= 0.003637
Saving checkpoint... 
Iteration: 1402293099, states[0] = -94.982282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423948882, states[0] = -95.046687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445760280, states[0] = -94.951067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468147426, states[0] = -73.637366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492308240, states[0] = -94.993482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1518926518, states[0] = 18.838510, states[40]= 0.008090
Saving checkpoint... 
Iteration: 1544268515, states[0] = -95.131976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565344544, states[0] = -95.272206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589523552, states[0] = -70.135082, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1616410082, states[0] = 24.160697, states[40]= 0.052443
Saving checkpoint... 
Iteration: 1643307119, states[0] = -95.229080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1670044402, states[0] = -95.280658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1696839771, states[0] = 12.370679, states[40]= 0.006175
Saving checkpoint... 
Iteration: 1723792865, states[0] = -95.322668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750669966, states[0] = -95.153253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777455932, states[0] = -95.292871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1804341189, states[0] = -95.065748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831209733, states[0] = -94.904450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858108621, states[0] = -30.644021, states[40]= 0.000424
Saving checkpoint... 
Iteration: 1884207248, states[0] = -94.878329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910887070, states[0] = -95.033693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1937633068, states[0] = -55.356279, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1964448853, states[0] = -95.046835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991308053, states[0] = -94.993244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2018083498, states[0] = -6.399000, states[40]= 0.003126
Saving checkpoint... 
Iteration: 2044948682, states[0] = -95.046276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071822780, states[0] = -95.002434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098583432, states[0] = -6.343017, states[40]= 0.003138
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.929523
 - CaMKt in component CaMK (millimolar): 0.006831
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.559607
 - nass in component intracellular_ions (millimolar): 6.559667
 - ki in component intracellular_ions (millimolar): 145.419682
 - kss in component intracellular_ions (millimolar): 145.419662
 - cansr in component intracellular_ions (millimolar): 1.305700
 - cajsr in component intracellular_ions (millimolar): 1.268137
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003608
 - hf in component INa (dimensionless): 0.880480
 - hs in component INa (dimensionless): 0.880476
 - j in component INa (dimensionless): 0.880448
 - hsp in component INa (dimensionless): 0.726735
 - jp in component INa (dimensionless): 0.880429
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711393
 - hLp in component INaL (dimensionless): 0.455091
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.624471
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.699964
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936952
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999892
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001582
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330306
 - xs1 in component IKs (dimensionless): 0.237065
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997330
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:32:11 (69589): called boinc_finish(0)

</stderr_txt>
]]>