𝕏

Task 55881857

Name HuVeMOp_20240703115557113738_ORdGradInc_k_26-CLVPET_Block_K1_75-conf_14_1
Workunit 26536929
Created 3 Jul 2024, 9:56:41 UTC
Sent 3 Jul 2024, 10:57:03 UTC
Report deadline 6 Jul 2024, 13:49:51 UTC
Received 3 Jul 2024, 20:31:46 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 2 hours 5 min 28 sec
CPU time 1 hours 57 min 33 sec
Validate state Valid
Credit 51.60
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.84 MB
Peak swap size 4.13 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-CLVPET_Block_K1_75-conf_14.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-CLVPET_Block_K1_75-conf_14_1_r726303209_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703115557113738_ORdGradInc_k_26-CLVPET_Block_K1_75-conf_14_1_r726303209_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 105.356603
     * GNaL_b in INaL: 0.006036
     * Gto_b in Ito: 0.085940
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032326
     * GKs_b in IKs: 0.001914
     * GK1_b in IK1: 0.040701
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.243793
     * GKb_b in IKb: 0.003828
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034755
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10979941, states[0] = -91.879833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21820782, states[0] = -91.186819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33010130, states[0] = 27.629702, states[40]= 0.045103
Saving checkpoint... 
Iteration: 44240258, states[0] = -88.801497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55531424, states[0] = 24.317214, states[40]= 0.001436
Saving checkpoint... 
Iteration: 66564392, states[0] = 11.518011, states[40]= 0.003594
Saving checkpoint... 
Iteration: 77689684, states[0] = -78.188903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88451099, states[0] = -91.308086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99706611, states[0] = -83.040617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110840816, states[0] = -90.968143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121861252, states[0] = -91.061182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133166134, states[0] = -68.213835, states[40]= 0.000003
Saving checkpoint... 
Iteration: 143933839, states[0] = -91.250876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155290437, states[0] = -90.493592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166390510, states[0] = -91.151541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176165891, states[0] = -68.050279, states[40]= 0.000003
Saving checkpoint... 
Iteration: 186894825, states[0] = -91.161442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197660993, states[0] = -65.389022, states[40]= 0.000005
Saving checkpoint... 
Iteration: 208767397, states[0] = -89.974437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219173787, states[0] = -71.805711, states[40]= 0.000002
Saving checkpoint... 
Iteration: 230617823, states[0] = -29.735162, states[40]= 0.000904
Saving checkpoint... 
Iteration: 241449425, states[0] = -91.264882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252057119, states[0] = 14.814398, states[40]= 0.003056
Saving checkpoint... 
Iteration: 263126569, states[0] = -38.030800, states[40]= 0.000413
Saving checkpoint... 
Iteration: 274683765, states[0] = -75.851220, states[40]= 0.000001
Saving checkpoint... 
Iteration: 285078968, states[0] = 4.284017, states[40]= 0.004370
Saving checkpoint... 
Iteration: 296330507, states[0] = -90.882199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306411532, states[0] = -91.199101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317032257, states[0] = 24.176195, states[40]= 0.001491
Saving checkpoint... 
Iteration: 327519469, states[0] = 27.415814, states[40]= 0.002884
Saving checkpoint... 
Iteration: 338756507, states[0] = -89.540084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349779896, states[0] = -90.296501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366463456, states[0] = -91.280193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378908455, states[0] = -91.191790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390580352, states[0] = 3.473768, states[40]= 0.004389
Saving checkpoint... 
Iteration: 403377270, states[0] = -91.104092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419088258, states[0] = -1.748597, states[40]= 0.004119
Saving checkpoint... 
Iteration: 430748204, states[0] = -89.065843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442428965, states[0] = -91.232413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454003311, states[0] = 35.150880, states[40]= 0.414208
Saving checkpoint... 
Iteration: 464041828, states[0] = 20.812309, states[40]= 0.001957
Saving checkpoint... 
Iteration: 477605264, states[0] = -17.402992, states[40]= 0.001385
Saving checkpoint... 
Iteration: 489312338, states[0] = -90.741095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499617433, states[0] = -29.355459, states[40]= 0.000924
Saving checkpoint... 
Iteration: 510844590, states[0] = -90.964018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521857084, states[0] = -91.024674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532497739, states[0] = -91.307013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543366625, states[0] = -91.064447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554014685, states[0] = 27.847925, states[40]= 0.010303
Saving checkpoint... 
Iteration: 564452912, states[0] = -91.267150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574792699, states[0] = -90.517111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585478119, states[0] = -91.292930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596407374, states[0] = -91.188242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607072420, states[0] = 7.827553, states[40]= 0.004126
Saving checkpoint... 
Iteration: 617912108, states[0] = -91.198749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629483046, states[0] = -91.296658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640109449, states[0] = -21.592900, states[40]= 0.001152
Saving checkpoint... 
Iteration: 651002805, states[0] = 37.668007, states[40]= 0.460785
Saving checkpoint... 
Iteration: 661753113, states[0] = -89.362569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673163047, states[0] = -66.522932, states[40]= 0.000004
Saving checkpoint... 
Iteration: 684264268, states[0] = -89.862919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694803671, states[0] = -90.653758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705415799, states[0] = -91.206153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715796782, states[0] = -90.571894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726718850, states[0] = -85.571169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737659484, states[0] = -64.502510, states[40]= 0.000006
Saving checkpoint... 
Iteration: 748633378, states[0] = -44.376734, states[40]= 0.000179
Saving checkpoint... 
Iteration: 759462340, states[0] = -91.277094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770113846, states[0] = -25.896336, states[40]= 0.001060
Saving checkpoint... 
Iteration: 781253293, states[0] = -89.371709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792146753, states[0] = -55.876196, states[40]= 0.000029
Saving checkpoint... 
Iteration: 802481323, states[0] = -91.294486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812810393, states[0] = -90.721435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823758241, states[0] = -89.618190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834623788, states[0] = -35.405116, states[40]= 0.000557
Saving checkpoint... 
Iteration: 845147857, states[0] = -56.719508, states[40]= 0.000025
Saving checkpoint... 
Iteration: 856563451, states[0] = 12.090433, states[40]= 0.003544
Saving checkpoint... 
Iteration: 866954285, states[0] = -91.267375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877784194, states[0] = -90.377694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889022837, states[0] = 26.795475, states[40]= 0.001722
Saving checkpoint... 
Iteration: 900187882, states[0] = -77.329907, states[40]= 0.000001
Saving checkpoint... 
Iteration: 910267399, states[0] = -89.968217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921374978, states[0] = -91.093621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931965668, states[0] = -91.279747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940842590, states[0] = -90.951139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951671773, states[0] = -70.889371, states[40]= 0.000002
Saving checkpoint... 
Iteration: 962795964, states[0] = -90.559943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974385311, states[0] = -91.127363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985003385, states[0] = 34.827033, states[40]= 0.406462
Saving checkpoint... 
Iteration: 995823467, states[0] = -90.829582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007978569, states[0] = -91.291271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019355140, states[0] = -91.013459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031695231, states[0] = -79.741252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043580181, states[0] = 3.576762, states[40]= 0.004387
Saving checkpoint... 
Iteration: 1056077239, states[0] = 5.265712, states[40]= 0.004328
Saving checkpoint... 
Iteration: 1068929618, states[0] = -91.230514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081780710, states[0] = -90.309265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094445557, states[0] = -91.254990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106314582, states[0] = -90.757895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118306879, states[0] = -90.685415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130819841, states[0] = -90.801263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142611650, states[0] = -23.756773, states[40]= 0.001106
Saving checkpoint... 
Iteration: 1155132317, states[0] = -43.394518, states[40]= 0.000205
Saving checkpoint... 
Iteration: 1165905514, states[0] = -91.181132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177359547, states[0] = -91.032246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189021361, states[0] = 27.095250, states[40]= 0.002062
Saving checkpoint... 
Iteration: 1198778608, states[0] = -90.264270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209075495, states[0] = 6.220091, states[40]= 0.004268
Saving checkpoint... 
Iteration: 1219434383, states[0] = -91.237721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229736613, states[0] = -88.087908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240445204, states[0] = -91.253799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250791314, states[0] = -90.493291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260531202, states[0] = 24.516225, states[40]= 0.001458
Saving checkpoint... 
Iteration: 1271201168, states[0] = -81.479826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281839330, states[0] = -90.931231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292807695, states[0] = -90.692756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303571116, states[0] = 8.485403, states[40]= 0.004055
Saving checkpoint... 
Iteration: 1314268047, states[0] = -89.986466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325145619, states[0] = -54.987988, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1337106253, states[0] = -18.397472, states[40]= 0.001304
Saving checkpoint... 
Iteration: 1348575048, states[0] = 6.459794, states[40]= 0.004250
Saving checkpoint... 
Iteration: 1359665248, states[0] = -67.694396, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1371463313, states[0] = -91.275185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382515911, states[0] = 27.796100, states[40]= 0.007131
Saving checkpoint... 
Iteration: 1393515078, states[0] = 27.836504, states[40]= 0.009137
Saving checkpoint... 
Iteration: 1404682771, states[0] = -75.470482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1415506461, states[0] = 28.484087, states[40]= 0.153985
Saving checkpoint... 
Iteration: 1426994615, states[0] = -91.300831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438493062, states[0] = -91.299797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449315338, states[0] = -90.762680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461134735, states[0] = -45.619957, states[40]= 0.000150
Saving checkpoint... 
Iteration: 1473095882, states[0] = -8.107897, states[40]= 0.002962
Saving checkpoint... 
Iteration: 1485300526, states[0] = -90.614009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497333236, states[0] = -90.893602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509668869, states[0] = -84.810945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1520941087, states[0] = -92.223322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1532920347, states[0] = -71.013671, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1543715526, states[0] = -90.683788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1554877210, states[0] = -90.578189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565019934, states[0] = 26.586951, states[40]= 0.002332
Saving checkpoint... 
Iteration: 1577247890, states[0] = -83.716260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588838468, states[0] = -88.590187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600000733, states[0] = -88.864963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1612150639, states[0] = -88.745064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622492574, states[0] = -87.113404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633839139, states[0] = -87.291024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644770443, states[0] = -86.723248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1656092207, states[0] = -87.235727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666731990, states[0] = -86.616276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678141711, states[0] = -87.626117, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -86.130722
 - CaMKt in component CaMK (millimolar): 0.001065
 - cass in component intracellular_ions (millimolar): 0.000084
 - nai in component intracellular_ions (millimolar): 6.176161
 - nass in component intracellular_ions (millimolar): 6.176242
 - ki in component intracellular_ions (millimolar): 145.729955
 - kss in component intracellular_ions (millimolar): 145.729943
 - cansr in component intracellular_ions (millimolar): 1.519805
 - cajsr in component intracellular_ions (millimolar): 1.519947
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.008754
 - hf in component INa (dimensionless): 0.634420
 - hs in component INa (dimensionless): 0.634437
 - j in component INa (dimensionless): 0.634520
 - hsp in component INa (dimensionless): 0.385261
 - jp in component INa (dimensionless): 0.634567
 - mL in component INaL (dimensionless): 0.000262
 - hL in component INaL (dimensionless): 0.455560
 - hLp in component INaL (dimensionless): 0.269414
 - a in component Ito (dimensionless): 0.001126
 - iF in component Ito (dimensionless): 0.999395
 - iS in component Ito (dimensionless): 0.994881
 - ap in component Ito (dimensionless): 0.000574
 - iFp in component Ito (dimensionless): 0.999395
 - iSp in component Ito (dimensionless): 0.997183
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998855
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002658
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.009138
 - xs1 in component IKs (dimensionless): 0.023904
 - xs2 in component IKs (dimensionless): 0.000234
 - xk1 in component IK1 (dimensionless): 0.998882
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:30:41 (32046): called boinc_finish(0)

</stderr_txt>
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