𝕏

Task 55879970

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_215_2
Workunit 26356751
Created 3 Jul 2024, 5:51:02 UTC
Sent 3 Jul 2024, 10:43:54 UTC
Report deadline 6 Jul 2024, 10:43:54 UTC
Received 6 Jul 2024, 17:27:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232308
Run time 2 hours 33 min 19 sec
CPU time 2 hours 27 min 30 sec
Validate state Valid
Credit 46.61
Device peak FLOPS 4.92 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_215.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_215_2_r1553403358_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_215_2_r1553403358_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.020766
     * GNaL_b in INaL: 0.005785
     * Gto_b in Ito: 0.085281
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032249
     * GKs_b in IKs: 0.001939
     * GK1_b in IK1: 0.162074
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.773826
     * GKb_b in IKb: 0.003811
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029410
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9728955, states[0] = -19.830147, states[40]= 0.001184
Saving checkpoint... 
Iteration: 19592563, states[0] = -64.202429, states[40]= 0.000004
Saving checkpoint... 
Iteration: 29516489, states[0] = 18.755563, states[40]= 0.011768
Saving checkpoint... 
Iteration: 39443440, states[0] = -87.129507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49485189, states[0] = -87.799511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59636496, states[0] = -87.753304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69448456, states[0] = -87.629762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79412629, states[0] = -53.781353, states[40]= 0.000022
Saving checkpoint... 
Iteration: 89592051, states[0] = -75.927710, states[40]= 0.000001
Saving checkpoint... 
Iteration: 99915714, states[0] = -61.513148, states[40]= 0.000007
Saving checkpoint... 
Iteration: 110180016, states[0] = 16.284118, states[40]= 0.009032
Saving checkpoint... 
Iteration: 120368873, states[0] = -0.216294, states[40]= 0.005995
Saving checkpoint... 
Iteration: 130589833, states[0] = -79.123523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140534525, states[0] = -1.219660, states[40]= 0.005773
Saving checkpoint... 
Iteration: 150126817, states[0] = -87.757531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160212692, states[0] = -18.532290, states[40]= 0.001462
Saving checkpoint... 
Iteration: 170151267, states[0] = 40.281394, states[40]= 0.069552
Saving checkpoint... 
Iteration: 180052270, states[0] = -30.182800, states[40]= 0.000515
Saving checkpoint... 
Iteration: 189898873, states[0] = -50.036379, states[40]= 0.000039
Saving checkpoint... 
Iteration: 199793173, states[0] = -87.774844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209863760, states[0] = -4.282927, states[40]= 0.004985
Saving checkpoint... 
Iteration: 219923906, states[0] = -86.942378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229970238, states[0] = -87.818349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239580108, states[0] = -80.888059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249502162, states[0] = 14.771629, states[40]= 0.008419
Saving checkpoint... 
Iteration: 259452735, states[0] = -87.770686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268900678, states[0] = -64.532355, states[40]= 0.000004
Saving checkpoint... 
Iteration: 278812460, states[0] = 24.360868, states[40]= 0.087677
Saving checkpoint... 
Iteration: 288952095, states[0] = -87.778964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299046543, states[0] = -38.739899, states[40]= 0.000192
Saving checkpoint... 
Iteration: 308741816, states[0] = -83.291681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318838046, states[0] = 8.754485, states[40]= 0.007357
Saving checkpoint... 
Iteration: 328387296, states[0] = -53.298764, states[40]= 0.000024
Saving checkpoint... 
Iteration: 338170303, states[0] = 8.145028, states[40]= 0.007281
Saving checkpoint... 
Iteration: 348158201, states[0] = 15.199307, states[40]= 0.008560
Saving checkpoint... 
Iteration: 357853873, states[0] = -10.476531, states[40]= 0.003168
Saving checkpoint... 
Iteration: 367651028, states[0] = 17.895953, states[40]= 0.010333
Saving checkpoint... 
Iteration: 377188750, states[0] = -15.337463, states[40]= 0.001996
Saving checkpoint... 
Iteration: 386839930, states[0] = 1.907455, states[40]= 0.006406
Saving checkpoint... 
Iteration: 396843614, states[0] = -2.677075, states[40]= 0.005418
Saving checkpoint... 
Iteration: 406489928, states[0] = 12.718833, states[40]= 0.007933
Saving checkpoint... 
Iteration: 416246559, states[0] = -87.626729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426133128, states[0] = 22.880503, states[40]= 0.056715
Saving checkpoint... 
Iteration: 435884001, states[0] = -64.567143, states[40]= 0.000004
Saving checkpoint... 
Iteration: 445797999, states[0] = 22.789757, states[40]= 0.054664
Saving checkpoint... 
Iteration: 455691193, states[0] = -29.936595, states[40]= 0.000527
Saving checkpoint... 
Iteration: 465226310, states[0] = -83.441873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474850672, states[0] = -22.507633, states[40]= 0.001019
Saving checkpoint... 
Iteration: 484583258, states[0] = -87.714361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494269927, states[0] = -87.795608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503899853, states[0] = -87.467932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513565161, states[0] = -87.442810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523428947, states[0] = -87.779602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533175729, states[0] = -19.019172, states[40]= 0.001396
Saving checkpoint... 
Iteration: 543103368, states[0] = -87.811340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552884096, states[0] = -83.326954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563125406, states[0] = 20.469679, states[40]= 0.018397
Saving checkpoint... 
Iteration: 573427122, states[0] = -87.790476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583460587, states[0] = 18.893496, states[40]= 0.011961
Saving checkpoint... 
Iteration: 593619226, states[0] = 21.634359, states[40]= 0.031379
Saving checkpoint... 
Iteration: 603255817, states[0] = -87.784821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612957207, states[0] = 19.079879, states[40]= 0.012397
Saving checkpoint... 
Iteration: 622993261, states[0] = -9.450890, states[40]= 0.003461
Saving checkpoint... 
Iteration: 633141107, states[0] = 7.927656, states[40]= 0.007254
Saving checkpoint... 
Iteration: 642447394, states[0] = 21.742236, states[40]= 0.033163
Saving checkpoint... 
Iteration: 652312617, states[0] = 2.582019, states[40]= 0.006520
Saving checkpoint... 
Iteration: 661690687, states[0] = -58.276885, states[40]= 0.000011
Saving checkpoint... 
Iteration: 671541291, states[0] = -85.322696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681738902, states[0] = -87.751605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691443619, states[0] = 21.319198, states[40]= 0.026766
Saving checkpoint... 
Iteration: 701291450, states[0] = 14.115397, states[40]= 0.008235
Saving checkpoint... 
Iteration: 711214585, states[0] = -87.564869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721290074, states[0] = 13.748259, states[40]= 0.008146
Saving checkpoint... 
Iteration: 731121809, states[0] = 14.110401, states[40]= 0.008234
Saving checkpoint... 
Iteration: 740890680, states[0] = -87.712630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750987943, states[0] = -19.970843, states[40]= 0.001278
Saving checkpoint... 
Iteration: 760571757, states[0] = -87.778780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770378324, states[0] = -87.634986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780446807, states[0] = 16.015254, states[40]= 0.008897
Saving checkpoint... 
Iteration: 790613685, states[0] = 15.347703, states[40]= 0.008614
Saving checkpoint... 
Iteration: 800195420, states[0] = -85.524338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810148878, states[0] = -20.234811, states[40]= 0.001247
Saving checkpoint... 
Iteration: 820105234, states[0] = 18.151711, states[40]= 0.010661
Saving checkpoint... 
Iteration: 830176533, states[0] = -62.394713, states[40]= 0.000006
Saving checkpoint... 
Iteration: 840092030, states[0] = 22.722344, states[40]= 0.053143
Saving checkpoint... 
Iteration: 849877431, states[0] = -87.699959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859555918, states[0] = -87.756930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869516200, states[0] = -79.558296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879306956, states[0] = -17.843748, states[40]= 0.001562
Saving checkpoint... 
Iteration: 888519706, states[0] = -85.394797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898480655, states[0] = -30.510584, states[40]= 0.000498
Saving checkpoint... 
Iteration: 908532637, states[0] = -87.655032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918832944, states[0] = -60.247687, states[40]= 0.000008
Saving checkpoint... 
Iteration: 929109213, states[0] = 9.543468, states[40]= 0.007456
Saving checkpoint... 
Iteration: 939184462, states[0] = -86.738076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948862670, states[0] = -87.663133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958409343, states[0] = 26.851186, states[40]= 0.119616
Saving checkpoint... 
Iteration: 968325241, states[0] = -56.127320, states[40]= 0.000015
Saving checkpoint... 
Iteration: 978568574, states[0] = -87.835701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988788802, states[0] = -7.863492, states[40]= 0.003931
Saving checkpoint... 
Iteration: 998812787, states[0] = -42.745139, states[40]= 0.000112
Saving checkpoint... 
Iteration: 1009044194, states[0] = -87.768742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018869094, states[0] = -87.739975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028889043, states[0] = -87.813366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038682824, states[0] = -87.593549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048222429, states[0] = -87.819218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058306144, states[0] = -41.784048, states[40]= 0.000128
Saving checkpoint... 
Iteration: 1068540022, states[0] = -87.775121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078125396, states[0] = -24.955163, states[40]= 0.000827
Saving checkpoint... 
Iteration: 1087792236, states[0] = -26.564414, states[40]= 0.000719
Saving checkpoint... 
Iteration: 1097710043, states[0] = -87.796397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107377032, states[0] = -87.800543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117250911, states[0] = 13.486949, states[40]= 0.008087
Saving checkpoint... 
Iteration: 1127171917, states[0] = -87.522737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137366574, states[0] = -87.775431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147622062, states[0] = -30.035242, states[40]= 0.000522
Saving checkpoint... 
Iteration: 1157441304, states[0] = -11.478076, states[40]= 0.002895
Saving checkpoint... 
Iteration: 1167585677, states[0] = 9.326354, states[40]= 0.007429
Saving checkpoint... 
Iteration: 1177706007, states[0] = -87.808741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187752842, states[0] = 7.536863, states[40]= 0.007206
Saving checkpoint... 
Iteration: 1197947835, states[0] = -26.486600, states[40]= 0.000724
Saving checkpoint... 
Iteration: 1208143234, states[0] = -69.779870, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1217898760, states[0] = 18.163191, states[40]= 0.010675
Saving checkpoint... 
Iteration: 1227469383, states[0] = -61.231507, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1237531207, states[0] = -87.801956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247483459, states[0] = -85.171443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257700638, states[0] = -87.816536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267475934, states[0] = -78.837248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277113788, states[0] = -36.516398, states[40]= 0.000254
Saving checkpoint... 
Iteration: 1286806154, states[0] = -76.907993, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1296783571, states[0] = -43.560636, states[40]= 0.000100
Saving checkpoint... 
Iteration: 1306844999, states[0] = -87.758207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316841885, states[0] = -87.750039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326908081, states[0] = 5.655760, states[40]= 0.006969
Saving checkpoint... 
Iteration: 1337092518, states[0] = -15.003407, states[40]= 0.002063
Saving checkpoint... 
Iteration: 1347302718, states[0] = -80.970337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357305248, states[0] = -84.768991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367360423, states[0] = -87.828102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377502931, states[0] = -87.751665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386883470, states[0] = 17.393511, states[40]= 0.009810
Saving checkpoint... 
Iteration: 1396378648, states[0] = 19.170017, states[40]= 0.012628
Saving checkpoint... 
Iteration: 1405524766, states[0] = -87.832110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415512861, states[0] = -87.799897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425446698, states[0] = -56.874145, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1435220814, states[0] = 12.449827, states[40]= 0.007883
Saving checkpoint... 
Iteration: 1445397529, states[0] = 4.626237, states[40]= 0.006830
Saving checkpoint... 
Iteration: 1455277465, states[0] = -57.492133, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1465482818, states[0] = -87.700707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475492222, states[0] = -87.747903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485389997, states[0] = 7.350704, states[40]= 0.007183
Saving checkpoint... 
Iteration: 1494940021, states[0] = -57.278024, states[40]= 0.000013
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.711196
 - CaMKt in component CaMK (millimolar): 0.043533
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 7.024789
 - nass in component intracellular_ions (millimolar): 7.024938
 - ki in component intracellular_ions (millimolar): 144.892247
 - kss in component intracellular_ions (millimolar): 144.892215
 - cansr in component intracellular_ions (millimolar): 1.633323
 - cajsr in component intracellular_ions (millimolar): 1.195535
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007468
 - hf in component INa (dimensionless): 0.692313
 - hs in component INa (dimensionless): 0.692069
 - j in component INa (dimensionless): 0.681538
 - hsp in component INa (dimensionless): 0.447146
 - jp in component INa (dimensionless): 0.655092
 - mL in component INaL (dimensionless): 0.000194
 - hL in component INaL (dimensionless): 0.293378
 - hLp in component INaL (dimensionless): 0.136383
 - a in component Ito (dimensionless): 0.001012
 - iF in component Ito (dimensionless): 0.999540
 - iS in component Ito (dimensionless): 0.176033
 - ap in component Ito (dimensionless): 0.000516
 - iFp in component Ito (dimensionless): 0.999540
 - iSp in component Ito (dimensionless): 0.213154
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.804876
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.967207
 - jca in component ICaL (dimensionless): 0.948160
 - ffp in component ICaL (dimensionless): 0.999866
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009587
 - xrf in component IKr (dimensionless): 0.028299
 - xrs in component IKr (dimensionless): 0.783594
 - xs1 in component IKs (dimensionless): 0.458320
 - xs2 in component IKs (dimensionless): 0.001173
 - xk1 in component IK1 (dimensionless): 0.996809
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:33:17 (7830): called boinc_finish(0)

</stderr_txt>
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