𝕏

Task 55879154

Name HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_591_0
Workunit 26536211
Created 3 Jul 2024, 5:25:26 UTC
Sent 3 Jul 2024, 10:44:39 UTC
Report deadline 6 Jul 2024, 20:20:39 UTC
Received 4 Jul 2024, 22:44:48 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218836
Run time 1 hours 44 min 19 sec
CPU time 58 min 48 sec
Validate state Valid
Credit 62.67
Device peak FLOPS 5.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.70 MB
Peak swap size 5.30 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_591.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_591_0_r1103454830_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_591_0_r1103454830_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.910105
     * GNaL_b in INaL: 0.005781
     * Gto_b in Ito: 0.084142
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032312
     * GKs_b in IKs: 0.001901
     * GK1_b in IK1: 0.166385
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.455118
     * GKb_b in IKb: 0.003782
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032325
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15353718, states[0] = -95.078074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28560886, states[0] = 6.106793, states[40]= 0.004798
Saving checkpoint... 
Iteration: 41797295, states[0] = -94.996802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55086708, states[0] = -8.771801, states[40]= 0.002607
Saving checkpoint... 
Iteration: 68223095, states[0] = -94.892497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81481248, states[0] = -95.041194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94843770, states[0] = -95.000053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108162697, states[0] = -92.907527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121369065, states[0] = -95.007676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133503370, states[0] = 34.666549, states[40]= 0.148834
Saving checkpoint... 
Iteration: 146764532, states[0] = -94.935594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159977860, states[0] = -95.032171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173235109, states[0] = -94.897392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186619463, states[0] = -38.716547, states[40]= 0.000155
Saving checkpoint... 
Iteration: 199763412, states[0] = -94.933246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212868979, states[0] = -95.004902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226213374, states[0] = -94.861303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239516408, states[0] = 21.899575, states[40]= 0.014614
Saving checkpoint... 
Iteration: 252665741, states[0] = -93.948980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266074253, states[0] = 0.614350, states[40]= 0.004328
Saving checkpoint... 
Iteration: 279409493, states[0] = -95.017780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292700160, states[0] = -94.836035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305831367, states[0] = -94.987077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319210924, states[0] = -94.856656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332439702, states[0] = -95.024718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345624627, states[0] = -43.941710, states[40]= 0.000072
Saving checkpoint... 
Iteration: 358546638, states[0] = 12.876594, states[40]= 0.005026
Saving checkpoint... 
Iteration: 372032350, states[0] = 17.967228, states[40]= 0.005761
Saving checkpoint... 
Iteration: 385373892, states[0] = -95.006465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398772984, states[0] = -94.942890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408224901, states[0] = -94.880811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421572678, states[0] = 1.474812, states[40]= 0.004426
Saving checkpoint... 
Iteration: 434962413, states[0] = -95.028750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448124764, states[0] = -44.084032, states[40]= 0.000070
Saving checkpoint... 
Iteration: 461544257, states[0] = 13.779170, states[40]= 0.005082
Saving checkpoint... 
Iteration: 474760806, states[0] = -94.929867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484476228, states[0] = -95.030818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497776336, states[0] = -94.946121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510948692, states[0] = -95.026326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524097591, states[0] = -17.640427, states[40]= 0.001158
Saving checkpoint... 
Iteration: 536137977, states[0] = -58.548145, states[40]= 0.000007
Saving checkpoint... 
Iteration: 545903566, states[0] = -95.015962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558988034, states[0] = -95.032361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572354561, states[0] = -94.998474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585948145, states[0] = -95.026176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599215329, states[0] = -94.864423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612496004, states[0] = -95.033303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625648592, states[0] = -72.231313, states[40]= 0.000001
Saving checkpoint... 
Iteration: 635837242, states[0] = -94.990035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649078675, states[0] = -2.002486, states[40]= 0.003953
Saving checkpoint... 
Iteration: 662324722, states[0] = -94.983005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675693854, states[0] = -94.822907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689014118, states[0] = 22.274078, states[40]= 0.021494
Saving checkpoint... 
Iteration: 702394317, states[0] = -95.013149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715549318, states[0] = 11.843017, states[40]= 0.004978
Saving checkpoint... 
Iteration: 728704757, states[0] = -94.844751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742081001, states[0] = -3.527327, states[40]= 0.003684
Saving checkpoint... 
Iteration: 755350227, states[0] = -94.996383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768473346, states[0] = -95.030218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781975222, states[0] = -95.030482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795279595, states[0] = -94.949025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808716995, states[0] = -94.867219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822137520, states[0] = -58.022804, states[40]= 0.000007
Saving checkpoint... 
Iteration: 835361216, states[0] = -95.001177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848493796, states[0] = -95.032887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859390958, states[0] = -95.012003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872534669, states[0] = 17.208966, states[40]= 0.005551
Saving checkpoint... 
Iteration: 885812906, states[0] = -94.975404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898987279, states[0] = -95.032044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912268693, states[0] = -94.938168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925652135, states[0] = -77.960229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939009908, states[0] = 23.175478, states[40]= 0.053508
Saving checkpoint... 
Iteration: 952351218, states[0] = -94.996714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965630601, states[0] = -50.311485, states[40]= 0.000026
Saving checkpoint... 
Iteration: 979104402, states[0] = -24.137066, states[40]= 0.000741
Saving checkpoint... 
Iteration: 992407457, states[0] = -95.016745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005637302, states[0] = -57.773092, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1018936648, states[0] = -95.023646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032368755, states[0] = -95.004092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045908653, states[0] = -95.017032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059090551, states[0] = -11.084452, states[40]= 0.002120
Saving checkpoint... 
Iteration: 1072380343, states[0] = -95.008339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085640902, states[0] = -61.985791, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1098778096, states[0] = -94.947416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108758315, states[0] = -94.926595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122109922, states[0] = -29.411389, states[40]= 0.000492
Saving checkpoint... 
Iteration: 1135286499, states[0] = -94.955036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148567468, states[0] = 4.110143, states[40]= 0.004658
Saving checkpoint... 
Iteration: 1161885366, states[0] = -95.009993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175387158, states[0] = -95.010576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188788656, states[0] = -94.956861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202208214, states[0] = -94.851029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215638528, states[0] = -59.184317, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1228986874, states[0] = -95.031778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242334979, states[0] = -94.988436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255890826, states[0] = -95.011704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269328017, states[0] = -94.984540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282706295, states[0] = -94.847341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295812745, states[0] = -94.975029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309123973, states[0] = -43.262264, states[40]= 0.000080
Saving checkpoint... 
Iteration: 1322496474, states[0] = -95.032898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335607930, states[0] = -27.504342, states[40]= 0.000584
Saving checkpoint... 
Iteration: 1348874640, states[0] = -95.006116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362356092, states[0] = -94.998639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375818989, states[0] = -94.979032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388964147, states[0] = -95.028410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402079706, states[0] = -2.664069, states[40]= 0.003841
Saving checkpoint... 
Iteration: 1415567808, states[0] = 3.946496, states[40]= 0.004646
Saving checkpoint... 
Iteration: 1428888372, states[0] = -95.010807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442102896, states[0] = -22.700822, states[40]= 0.000810
Saving checkpoint... 
Iteration: 1455326420, states[0] = -94.983492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468759086, states[0] = -94.927253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482142972, states[0] = -64.529231, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1495504053, states[0] = 31.415010, states[40]= 0.156370
Saving checkpoint... 
Iteration: 1508994419, states[0] = -95.254736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1522311175, states[0] = -49.437660, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1535532799, states[0] = -81.635328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548918082, states[0] = 21.546374, states[40]= 0.013230
Saving checkpoint... 
Iteration: 1562246632, states[0] = -94.794635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1571614734, states[0] = -95.213071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584980713, states[0] = -17.042157, states[40]= 0.001361
Saving checkpoint... 
Iteration: 1594651499, states[0] = -95.031081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1607968776, states[0] = -95.281997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621245731, states[0] = 9.698742, states[40]= 0.005753
Saving checkpoint... 
Iteration: 1633658912, states[0] = -95.096362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647001023, states[0] = 47.598845, states[40]= 0.023716
Saving checkpoint... 
Iteration: 1660416552, states[0] = -95.222769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673615248, states[0] = -95.220875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686770149, states[0] = -95.130158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700087405, states[0] = -95.298614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1713361976, states[0] = 0.131851, states[40]= 0.004815
Saving checkpoint... 
Iteration: 1726580433, states[0] = -16.967830, states[40]= 0.001372
Saving checkpoint... 
Iteration: 1739897412, states[0] = -95.190240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753267741, states[0] = -4.250030, states[40]= 0.003998
Saving checkpoint... 
Iteration: 1766435290, states[0] = 14.798581, states[40]= 0.006408
Saving checkpoint... 
Iteration: 1779477550, states[0] = -95.148211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1792608007, states[0] = -47.948910, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1805968000, states[0] = -95.081050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1819115675, states[0] = -37.466894, states[40]= 0.000188
Saving checkpoint... 
Iteration: 1832290257, states[0] = -94.984049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845681686, states[0] = -94.810861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859049158, states[0] = 11.703110, states[40]= 0.004984
Saving checkpoint... 
Iteration: 1872138776, states[0] = -60.137995, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1885376453, states[0] = -95.011766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1898538621, states[0] = 15.792329, states[40]= 0.005296
Saving checkpoint... 
Iteration: 1911829965, states[0] = -94.987642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1924930337, states[0] = -95.023324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938315777, states[0] = -94.977680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951614691, states[0] = -34.053492, states[40]= 0.000292
Saving checkpoint... 
Iteration: 1965116296, states[0] = -35.599975, states[40]= 0.000239
Saving checkpoint... 
Iteration: 1978403665, states[0] = -95.015344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991706625, states[0] = -94.847684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005119012, states[0] = -38.249973, states[40]= 0.000166
Saving checkpoint... 
Iteration: 2018318145, states[0] = -94.978129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2031424053, states[0] = -95.020247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044845049, states[0] = -94.993070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058012590, states[0] = 22.534394, states[40]= 0.029201
Saving checkpoint... 
Iteration: 2071311210, states[0] = -94.973454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084381614, states[0] = -95.008081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2097701544, states[0] = -94.837534, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.908629
 - CaMKt in component CaMK (millimolar): 0.006987
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.559449
 - nass in component intracellular_ions (millimolar): 6.559509
 - ki in component intracellular_ions (millimolar): 145.417787
 - kss in component intracellular_ions (millimolar): 145.417768
 - cansr in component intracellular_ions (millimolar): 1.312936
 - cajsr in component intracellular_ions (millimolar): 1.274996
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880118
 - hs in component INa (dimensionless): 0.880114
 - j in component INa (dimensionless): 0.880085
 - hsp in component INa (dimensionless): 0.726052
 - jp in component INa (dimensionless): 0.880067
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710370
 - hLp in component INaL (dimensionless): 0.453033
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622215
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697283
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935627
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001605
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.328577
 - xs1 in component IKs (dimensionless): 0.240578
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:43:54 (6116): called boinc_finish(0)

</stderr_txt>
]]>


CoMBA Research Group Logo
University San Jorge Logo

©2024 Universidad San Jorge