𝕏

Task 55878032

Name HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_5000-conf_583_0
Workunit 26535650
Created 3 Jul 2024, 5:24:54 UTC
Sent 3 Jul 2024, 10:31:39 UTC
Report deadline 6 Jul 2024, 10:31:39 UTC
Received 5 Jul 2024, 22:45:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224115
Run time 1 hours 17 min 45 sec
CPU time 1 hours 3 min 56 sec
Validate state Valid
Credit 46.21
Device peak FLOPS 4.81 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.58 MB
Peak swap size 391.75 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_5000-conf_583.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_5000-conf_583_0_r1126267641_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_5000-conf_583_0_r1126267641_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.232646
     * GNaL_b in INaL: 0.005581
     * Gto_b in Ito: 0.088435
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031872
     * GKs_b in IKs: 0.001977
     * GK1_b in IK1: 0.161999
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.590129
     * GKb_b in IKb: 0.003776
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037067
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 23466938, states[0] = -94.168855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 40802919, states[0] = -94.178121, states[40]= 0.000001
Saving checkpoint... 
Iteration: 47370179, states[0] = -94.153533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 54303884, states[0] = -94.165321, states[40]= 0.000001
Saving checkpoint... 
Iteration: 61129356, states[0] = -94.187275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 68074585, states[0] = -94.164329, states[40]= 0.000001
Saving checkpoint... 
Iteration: 74652557, states[0] = -94.174180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 86401423, states[0] = -94.192752, states[40]= 0.000001
Saving checkpoint... 
Iteration: 96855752, states[0] = -94.187394, states[40]= 0.000001
Saving checkpoint... 
Iteration: 107475954, states[0] = -94.184641, states[40]= 0.000001
Saving checkpoint... 
Iteration: 116834850, states[0] = -94.192995, states[40]= 0.000001
Saving checkpoint... 
Iteration: 126580443, states[0] = -94.199360, states[40]= 0.000001
Saving checkpoint... 
Iteration: 137287523, states[0] = -94.191310, states[40]= 0.000001
Saving checkpoint... 
Iteration: 147560003, states[0] = 29.540350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160336971, states[0] = -93.846036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172079166, states[0] = -94.195871, states[40]= 0.000001
Saving checkpoint... 
Iteration: 183792621, states[0] = -94.211256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 195215145, states[0] = -32.706648, states[40]= 0.004151
Saving checkpoint... 
Iteration: 205165100, states[0] = -11.678927, states[40]= 0.000613
Saving checkpoint... 
Iteration: 218657026, states[0] = -94.216062, states[40]= 0.000001
Saving checkpoint... 
Iteration: 231277234, states[0] = -94.212375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 242475452, states[0] = -94.193999, states[40]= 0.000001
Saving checkpoint... 
Iteration: 255430107, states[0] = -94.077931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265619365, states[0] = -94.205305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 278244636, states[0] = -94.221453, states[40]= 0.000001
Saving checkpoint... 
Iteration: 290879012, states[0] = -94.223469, states[40]= 0.000001
Saving checkpoint... 
Iteration: 301508210, states[0] = -94.205985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 311404787, states[0] = -94.208469, states[40]= 0.000001
Saving checkpoint... 
Iteration: 324745550, states[0] = -94.195058, states[40]= 0.000001
Saving checkpoint... 
Iteration: 336674860, states[0] = -94.202231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 348141057, states[0] = -94.209333, states[40]= 0.000001
Saving checkpoint... 
Iteration: 360561073, states[0] = -94.186052, states[40]= 0.000001
Saving checkpoint... 
Iteration: 374510354, states[0] = -94.196910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 388767872, states[0] = -94.211688, states[40]= 0.000001
Saving checkpoint... 
Iteration: 401484984, states[0] = -94.205701, states[40]= 0.000001
Saving checkpoint... 
Iteration: 413360935, states[0] = -94.222613, states[40]= 0.000001
Saving checkpoint... 
Iteration: 425299876, states[0] = -93.678181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436782985, states[0] = -94.199481, states[40]= 0.000001
Saving checkpoint... 
Iteration: 447356286, states[0] = -94.193197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 460006496, states[0] = 25.190190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471649443, states[0] = -94.201530, states[40]= 0.000001
Saving checkpoint... 
Iteration: 481615249, states[0] = -94.202117, states[40]= 0.000001
Saving checkpoint... 
Iteration: 494666346, states[0] = -94.194241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 507135868, states[0] = -94.194411, states[40]= 0.000001
Saving checkpoint... 
Iteration: 518024984, states[0] = -94.166703, states[40]= 0.000001
Saving checkpoint... 
Iteration: 530502719, states[0] = -94.152027, states[40]= 0.000001
Saving checkpoint... 
Iteration: 542245404, states[0] = -94.193143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 557773691, states[0] = -86.308195, states[40]= 0.000002
Saving checkpoint... 
Iteration: 584545901, states[0] = -94.194632, states[40]= 0.000001
Saving checkpoint... 
Iteration: 610738213, states[0] = -94.218238, states[40]= 0.000001
Saving checkpoint... 
Iteration: 637027742, states[0] = -94.194362, states[40]= 0.000001
Saving checkpoint... 
Iteration: 665285794, states[0] = -93.434378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696842384, states[0] = -94.196228, states[40]= 0.000001
Saving checkpoint... 
Iteration: 721270641, states[0] = -94.208625, states[40]= 0.000001
Saving checkpoint... 
Iteration: 750035732, states[0] = 33.708749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780472046, states[0] = -94.123902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809416753, states[0] = -94.194172, states[40]= 0.000001
Saving checkpoint... 
Iteration: 831770955, states[0] = -94.196127, states[40]= 0.000001
Saving checkpoint... 
Iteration: 858227133, states[0] = -94.215300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 885013927, states[0] = 30.673185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912023185, states[0] = -94.191941, states[40]= 0.000001
Saving checkpoint... 
Iteration: 936003319, states[0] = -94.215078, states[40]= 0.000001
Saving checkpoint... 
Iteration: 963282063, states[0] = -94.216954, states[40]= 0.000001
Saving checkpoint... 
Iteration: 988789878, states[0] = -94.205647, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1015269632, states[0] = -79.396571, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1039921174, states[0] = -94.187468, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1069684575, states[0] = -94.188904, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1095320952, states[0] = -93.776330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121091683, states[0] = -94.210687, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1145253706, states[0] = -60.526818, states[40]= 0.000109
Saving checkpoint... 
Iteration: 1168532193, states[0] = -94.212131, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1174734683, states[0] = -94.187538, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1180626214, states[0] = -94.198836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1187012553, states[0] = -94.189586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1193322283, states[0] = -94.215589, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1199769783, states[0] = -94.187036, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1205140698, states[0] = 0.414650, states[40]= 0.000265
Saving checkpoint... 
Iteration: 1211161959, states[0] = -94.207614, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1217625591, states[0] = 6.283262, states[40]= 0.000093
Saving checkpoint... 
Iteration: 1224459756, states[0] = -94.189882, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1230755292, states[0] = -94.213568, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1236325863, states[0] = -94.202376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1242912822, states[0] = -94.041596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249146442, states[0] = -94.194596, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1255345619, states[0] = -93.872640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262253583, states[0] = -94.186599, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1268361409, states[0] = -94.214937, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1274431340, states[0] = -94.189795, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1281287926, states[0] = -94.203076, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1287606762, states[0] = 13.305346, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1294302375, states[0] = -94.191462, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1300852609, states[0] = -94.214687, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1307410338, states[0] = -94.185123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1313997744, states[0] = -94.197201, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1320484733, states[0] = -94.130650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327643152, states[0] = -0.608138, states[40]= 0.000305
Saving checkpoint... 
Iteration: 1334147355, states[0] = -94.193815, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1339947538, states[0] = -94.184619, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1345467717, states[0] = -94.114487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351913305, states[0] = -94.189337, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1358347542, states[0] = -94.214185, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1364616271, states[0] = -94.186886, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1370874588, states[0] = -94.213916, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1377604503, states[0] = 14.146771, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1383144949, states[0] = -94.200778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1389570276, states[0] = -94.187129, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1395851715, states[0] = -94.213838, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1402083095, states[0] = -94.186882, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1407999872, states[0] = -94.142012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1414633566, states[0] = -94.186268, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1420600648, states[0] = -94.190254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1427170950, states[0] = -94.185809, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1433322897, states[0] = -94.213440, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1439368704, states[0] = -94.189166, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1445785376, states[0] = -94.212712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1451710526, states[0] = -94.191583, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1458246715, states[0] = -94.211105, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1464496239, states[0] = -94.187281, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1470566794, states[0] = -94.178400, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1490588536, states[0] = -94.185967, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.058880
 - CaMKt in component CaMK (millimolar): 0.001796
 - cass in component intracellular_ions (millimolar): 0.000096
 - nai in component intracellular_ions (millimolar): 7.818112
 - nass in component intracellular_ions (millimolar): 7.818265
 - ki in component intracellular_ions (millimolar): 143.994694
 - kss in component intracellular_ions (millimolar): 143.994680
 - cansr in component intracellular_ions (millimolar): 1.804737
 - cajsr in component intracellular_ions (millimolar): 1.806296
 - cai in component intracellular_ions (millimolar): 0.000101
 - m in component INa (dimensionless): 0.003940
 - hf in component INa (dimensionless): 0.864586
 - hs in component INa (dimensionless): 0.864586
 - j in component INa (dimensionless): 0.864587
 - hsp in component INa (dimensionless): 0.697450
 - jp in component INa (dimensionless): 0.864588
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706381
 - hLp in component INaL (dimensionless): 0.512349
 - a in component Ito (dimensionless): 0.000660
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.997221
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999039
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998071
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004447
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002428
 - xs1 in component IKs (dimensionless): 0.032225
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997550
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
00:00:46 (17535): called boinc_finish(0)

</stderr_txt>
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