𝕏

Task 55876632

Name HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_1000-conf_581_0
Workunit 26534950
Created 3 Jul 2024, 5:24:18 UTC
Sent 3 Jul 2024, 10:22:14 UTC
Report deadline 6 Jul 2024, 10:22:14 UTC
Received 8 Jul 2024, 13:01:21 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233458
Run time 1 hours 54 min 32 sec
CPU time 1 hours 53 min 54 sec
Validate state Task was reported too late to validate
Credit 0.00
Device peak FLOPS 3.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 6.21 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_1000-conf_581.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_1000-conf_581_0_r1545294961_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_1000-conf_581_0_r1545294961_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 105.806211
     * GNaL_b in INaL: 0.005564
     * Gto_b in Ito: 0.083832
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032120
     * GKs_b in IKs: 0.001893
     * GK1_b in IK1: 0.162418
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.376606
     * GKb_b in IKb: 0.003787
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036660
     * celltype in environment: 2.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5826748, states[0] = -94.280776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14419407, states[0] = -94.395681, states[40]= 0.000001
Saving checkpoint... 
Iteration: 22999763, states[0] = -94.462433, states[40]= 0.000001
Saving checkpoint... 
Iteration: 31545866, states[0] = 32.571649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39969419, states[0] = -94.492335, states[40]= 0.000001
Saving checkpoint... 
Iteration: 48597926, states[0] = 11.298093, states[40]= 0.000585
Saving checkpoint... 
Iteration: 53896699, states[0] = -94.459087, states[40]= 0.000001
Saving checkpoint... 
Iteration: 62481946, states[0] = -94.541981, states[40]= 0.000001
Saving checkpoint... 
Iteration: 71052974, states[0] = 28.949747, states[40]= 0.000002
Saving checkpoint... 
Iteration: 79570097, states[0] = 22.290747, states[40]= 0.000037
Saving checkpoint... 
Iteration: 88052544, states[0] = 28.831855, states[40]= 0.000002
Saving checkpoint... 
Iteration: 96641062, states[0] = -18.680258, states[40]= 0.007663
Saving checkpoint... 
Iteration: 105182860, states[0] = -42.425105, states[40]= 0.006137
Saving checkpoint... 
Iteration: 113799823, states[0] = -94.256281, states[40]= 0.000001
Saving checkpoint... 
Iteration: 122383180, states[0] = -94.498769, states[40]= 0.000001
Saving checkpoint... 
Iteration: 130839382, states[0] = -94.407995, states[40]= 0.000001
Saving checkpoint... 
Iteration: 139432413, states[0] = -94.556841, states[40]= 0.000001
Saving checkpoint... 
Iteration: 144894028, states[0] = -94.517155, states[40]= 0.000001
Saving checkpoint... 
Iteration: 146865764, states[0] = -94.471443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 152428761, states[0] = -94.554434, states[40]= 0.000001
Saving checkpoint... 
Iteration: 160833107, states[0] = -94.391514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 169315187, states[0] = -94.329445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177930645, states[0] = -94.555411, states[40]= 0.000001
Saving checkpoint... 
Iteration: 186427229, states[0] = -94.552060, states[40]= 0.000001
Saving checkpoint... 
Iteration: 194872630, states[0] = -94.482747, states[40]= 0.000001
Saving checkpoint... 
Iteration: 203445774, states[0] = -94.564663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 212158275, states[0] = -29.585643, states[40]= 0.018497
Saving checkpoint... 
Iteration: 220895759, states[0] = -94.515817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 229474890, states[0] = -94.577856, states[40]= 0.000001
Saving checkpoint... 
Iteration: 237613121, states[0] = 0.559387, states[40]= 0.005699
Saving checkpoint... 
Iteration: 243670127, states[0] = -35.777394, states[40]= 0.011980
Saving checkpoint... 
Iteration: 252398424, states[0] = -94.516066, states[40]= 0.000001
Saving checkpoint... 
Iteration: 261151431, states[0] = -26.143899, states[40]= 0.019102
Saving checkpoint... 
Iteration: 268993927, states[0] = -94.580784, states[40]= 0.000001
Saving checkpoint... 
Iteration: 277623531, states[0] = -6.714967, states[40]= 0.006819
Saving checkpoint... 
Iteration: 286127777, states[0] = -10.062174, states[40]= 0.006193
Saving checkpoint... 
Iteration: 294942381, states[0] = -94.552965, states[40]= 0.000001
Saving checkpoint... 
Iteration: 303663314, states[0] = -32.150422, states[40]= 0.015960
Saving checkpoint... 
Iteration: 312385973, states[0] = -94.492447, states[40]= 0.000001
Saving checkpoint... 
Iteration: 321219915, states[0] = -80.584984, states[40]= 0.000038
Saving checkpoint... 
Iteration: 330013669, states[0] = 33.595222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338797254, states[0] = -94.233173, states[40]= 0.000001
Saving checkpoint... 
Iteration: 347389555, states[0] = -94.493737, states[40]= 0.000001
Saving checkpoint... 
Iteration: 355795271, states[0] = -94.221106, states[40]= 0.000001
Saving checkpoint... 
Iteration: 364553492, states[0] = 28.115111, states[40]= 0.000004
Saving checkpoint... 
Iteration: 373495511, states[0] = -94.569714, states[40]= 0.000001
Saving checkpoint... 
Iteration: 381992493, states[0] = -94.567809, states[40]= 0.000001
Saving checkpoint... 
Iteration: 390521527, states[0] = 34.994334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399096611, states[0] = 9.595103, states[40]= 0.001547
Saving checkpoint... 
Iteration: 407795956, states[0] = -94.218728, states[40]= 0.000001
Saving checkpoint... 
Iteration: 416608172, states[0] = 3.500723, states[40]= 0.004246
Saving checkpoint... 
Iteration: 425266030, states[0] = -94.024230, states[40]= 0.000001
Saving checkpoint... 
Iteration: 430512787, states[0] = 33.220432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439022684, states[0] = 35.001164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444839040, states[0] = -94.380344, states[40]= 0.000001
Saving checkpoint... 
Iteration: 453449881, states[0] = -94.540228, states[40]= 0.000001
Saving checkpoint... 
Iteration: 461947315, states[0] = -94.537654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470524237, states[0] = 34.955221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479068147, states[0] = 22.497696, states[40]= 0.000043
Saving checkpoint... 
Iteration: 487516916, states[0] = 34.539458, states[40]= -0.000000
Saving checkpoint... 
Iteration: 495935786, states[0] = -94.525835, states[40]= 0.000001
Saving checkpoint... 
Iteration: 503735011, states[0] = -93.537287, states[40]= 0.000001
Saving checkpoint... 
Iteration: 512301382, states[0] = -94.233864, states[40]= 0.000001
Saving checkpoint... 
Iteration: 521150302, states[0] = -25.531616, states[40]= 0.018577
Saving checkpoint... 
Iteration: 529851761, states[0] = -94.403587, states[40]= 0.000001
Saving checkpoint... 
Iteration: 538653051, states[0] = -26.965360, states[40]= 0.019382
Saving checkpoint... 
Iteration: 547505041, states[0] = 26.388090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556292828, states[0] = -94.185570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 565049861, states[0] = 29.363463, states[40]= 0.000002
Saving checkpoint... 
Iteration: 573489209, states[0] = -94.545464, states[40]= 0.000001
Saving checkpoint... 
Iteration: 582082552, states[0] = 16.268128, states[40]= 0.000311
Saving checkpoint... 
Iteration: 590734059, states[0] = -93.445592, states[40]= 0.000001
Saving checkpoint... 
Iteration: 599579993, states[0] = 17.420918, states[40]= 0.000224
Saving checkpoint... 
Iteration: 608269599, states[0] = -94.031170, states[40]= 0.000001
Saving checkpoint... 
Iteration: 617006066, states[0] = 27.852233, states[40]= -0.000000
Saving checkpoint... 
Iteration: 625706224, states[0] = -62.290612, states[40]= 0.000522
Saving checkpoint... 
Iteration: 634304586, states[0] = -94.235054, states[40]= 0.000001
Saving checkpoint... 
Iteration: 642875071, states[0] = -94.438197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 651588472, states[0] = 13.535559, states[40]= 0.000628
Saving checkpoint... 
Iteration: 660223318, states[0] = -86.486692, states[40]= 0.000015
Saving checkpoint... 
Iteration: 668723793, states[0] = -87.193104, states[40]= 0.000013
Saving checkpoint... 
Iteration: 677299313, states[0] = -94.205348, states[40]= 0.000001
Saving checkpoint... 
Iteration: 685941593, states[0] = -94.508897, states[40]= 0.000001
Saving checkpoint... 
Iteration: 694432421, states[0] = -94.501117, states[40]= 0.000001
Saving checkpoint... 
Iteration: 703038148, states[0] = 32.765847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711683458, states[0] = -44.106293, states[40]= 0.005314
Saving checkpoint... 
Iteration: 720189565, states[0] = -48.510043, states[40]= 0.003242
Saving checkpoint... 
Iteration: 728686490, states[0] = -46.250603, states[40]= 0.004202
Saving checkpoint... 
Iteration: 734585428, states[0] = 14.960501, states[40]= 0.000437
Saving checkpoint... 
Iteration: 742909313, states[0] = -94.474142, states[40]= 0.000001
Saving checkpoint... 
Iteration: 751543025, states[0] = 31.482698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760122202, states[0] = -5.637960, states[40]= 0.006856
Saving checkpoint... 
Iteration: 768517316, states[0] = 34.627233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776992336, states[0] = -94.523811, states[40]= 0.000001
Saving checkpoint... 
Iteration: 785549057, states[0] = 29.639062, states[40]= 0.000002
Saving checkpoint... 
Iteration: 794009952, states[0] = 31.551171, states[40]= -0.000000
Saving checkpoint... 
Iteration: 802561708, states[0] = 25.088961, states[40]= 0.000015
Saving checkpoint... 
Iteration: 811146445, states[0] = -23.360960, states[40]= 0.015482
Saving checkpoint... 
Iteration: 819862217, states[0] = -94.394104, states[40]= 0.000001
Saving checkpoint... 
Iteration: 828557404, states[0] = 26.723720, states[40]= 0.000007
Saving checkpoint... 
Iteration: 837111415, states[0] = 1.647350, states[40]= 0.005119
Saving checkpoint... 
Iteration: 845915458, states[0] = -94.469066, states[40]= 0.000001
Saving checkpoint... 
Iteration: 854979507, states[0] = -94.510497, states[40]= 0.000001
Saving checkpoint... 
Iteration: 863710604, states[0] = -66.852076, states[40]= 0.000268
Saving checkpoint... 
Iteration: 872331486, states[0] = -94.310000, states[40]= 0.000001
Saving checkpoint... 
Iteration: 879680591, states[0] = -42.152242, states[40]= 0.006507
Saving checkpoint... 
Iteration: 888486080, states[0] = -94.509300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 897133080, states[0] = -14.186192, states[40]= 0.005706
Saving checkpoint... 
Iteration: 905657182, states[0] = -29.021947, states[40]= 0.018765
Saving checkpoint... 
Iteration: 914104674, states[0] = 5.472488, states[40]= 0.003180
Saving checkpoint... 
Iteration: 922714886, states[0] = -72.262498, states[40]= 0.000122
Saving checkpoint... 
Iteration: 931255012, states[0] = -93.871489, states[40]= 0.000001
Saving checkpoint... 
Iteration: 939701721, states[0] = -58.197408, states[40]= 0.000929
Saving checkpoint... 
Iteration: 948149620, states[0] = -25.123841, states[40]= 0.018040
Saving checkpoint... 
Iteration: 956567737, states[0] = 22.688284, states[40]= 0.000040
Saving checkpoint... 
Iteration: 964787329, states[0] = -94.108721, states[40]= 0.000001
Saving checkpoint... 
Iteration: 970227814, states[0] = -91.482313, states[40]= 0.000004
Saving checkpoint... 
Iteration: 978674478, states[0] = -38.278184, states[40]= 0.009498
Saving checkpoint... 
Iteration: 987339279, states[0] = -94.320341, states[40]= 0.000001
Saving checkpoint... 
Iteration: 996061467, states[0] = 25.192113, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1004590770, states[0] = 12.468196, states[40]= 0.000802
Saving checkpoint... 
Iteration: 1013269386, states[0] = -93.984127, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1021896177, states[0] = -94.427411, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1030700069, states[0] = -56.800587, states[40]= 0.001124
Saving checkpoint... 
Iteration: 1039471855, states[0] = -94.486702, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1048151760, states[0] = -26.251142, states[40]= 0.018929
Saving checkpoint... 
Iteration: 1056594635, states[0] = 10.608874, states[40]= 0.001218
Saving checkpoint... 
Iteration: 1065104404, states[0] = 5.630155, states[40]= 0.003090
Saving checkpoint... 
Iteration: 1073449608, states[0] = -94.471001, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1081900476, states[0] = -94.426093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1090413406, states[0] = -94.439692, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1098967586, states[0] = -94.478069, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1107624357, states[0] = -7.235990, states[40]= 0.006628
Saving checkpoint... 
Iteration: 1116287561, states[0] = -94.093080, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1124908709, states[0] = -94.430852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1133361214, states[0] = -94.356932, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1141932457, states[0] = -94.451241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1150528223, states[0] = 34.641821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159075849, states[0] = 19.274322, states[40]= 0.000125
Saving checkpoint... 
Iteration: 1167558879, states[0] = 26.189068, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1175924485, states[0] = -94.440765, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1184623594, states[0] = -6.637313, states[40]= 0.006707
Saving checkpoint... 
Iteration: 1193274188, states[0] = -93.998552, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1198640087, states[0] = -19.307986, states[40]= 0.008656
Saving checkpoint... 
Iteration: 1207133038, states[0] = -14.101858, states[40]= 0.005661
Saving checkpoint... 
Iteration: 1215800697, states[0] = -94.151293, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1224251906, states[0] = -93.808199, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1232639567, states[0] = -18.945546, states[40]= 0.008218
Saving checkpoint... 
Iteration: 1241003261, states[0] = 20.793090, states[40]= -0.000016
Saving checkpoint... 
Iteration: 1249589699, states[0] = 12.989609, states[40]= 0.000707
Saving checkpoint... 
Iteration: 1258185126, states[0] = -45.247252, states[40]= 0.004668
Saving checkpoint... 
Iteration: 1266797015, states[0] = -94.127375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1275381825, states[0] = -94.378554, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1283893365, states[0] = -94.394441, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1292437987, states[0] = -94.438779, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1300887770, states[0] = -94.384716, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1306848231, states[0] = -94.308069, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1315532177, states[0] = 34.054177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324144559, states[0] = -22.184130, states[40]= 0.013254
Saving checkpoint... 
Iteration: 1332835892, states[0] = -94.271787, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1341261545, states[0] = -93.883904, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1349860439, states[0] = -94.331211, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1358475531, states[0] = -94.452893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1367009124, states[0] = 30.928265, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1375490074, states[0] = -94.456555, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1384272782, states[0] = -93.967306, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1393012356, states[0] = 33.052781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401648202, states[0] = -24.295926, states[40]= 0.016810
Saving checkpoint... 
Iteration: 1410347639, states[0] = -94.294960, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1419209769, states[0] = -65.894777, states[40]= 0.000305
Saving checkpoint... 
Iteration: 1427844292, states[0] = -94.284419, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1435610823, states[0] = 2.057872, states[40]= 0.004821
Saving checkpoint... 
Iteration: 1444131838, states[0] = -13.119260, states[40]= 0.005626
Saving checkpoint... 
Iteration: 1452634489, states[0] = -15.185972, states[40]= 0.005785
Saving checkpoint... 
Iteration: 1461220671, states[0] = -81.642084, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1469546127, states[0] = 30.600855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1478068510, states[0] = 22.397042, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1486524746, states[0] = 34.976904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495035166, states[0] = 33.481728, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.321680
 - CaMKt in component CaMK (millimolar): 0.053155
 - cass in component intracellular_ions (millimolar): 0.000105
 - nai in component intracellular_ions (millimolar): 8.606855
 - nass in component intracellular_ions (millimolar): 8.607059
 - ki in component intracellular_ions (millimolar): 142.198552
 - kss in component intracellular_ions (millimolar): 142.198514
 - cansr in component intracellular_ions (millimolar): 2.841769
 - cajsr in component intracellular_ions (millimolar): 2.794177
 - cai in component intracellular_ions (millimolar): 0.000110
 - m in component INa (dimensionless): 0.003837
 - hf in component INa (dimensionless): 0.869564
 - hs in component INa (dimensionless): 0.869551
 - j in component INa (dimensionless): 0.869462
 - hsp in component INa (dimensionless): 0.706410
 - jp in component INa (dimensionless): 0.869392
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.672060
 - hLp in component INaL (dimensionless): 0.383688
 - a in component Ito (dimensionless): 0.000648
 - iF in component Ito (dimensionless): 0.999856
 - iS in component Ito (dimensionless): 0.549538
 - ap in component Ito (dimensionless): 0.000330
 - iFp in component Ito (dimensionless): 0.999856
 - iSp in component Ito (dimensionless): 0.610849
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.864728
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999496
 - jca in component ICaL (dimensionless): 0.999928
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.006220
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.447006
 - xs1 in component IKs (dimensionless): 0.342885
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997486
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
07:26:18 (4616): called boinc_finish(0)

</stderr_txt>
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