𝕏

Task 55876134

Name HuVeMOp_20240703071643700359_ORdGradInc_k_26-Schmidt_666-conf_280_0
Workunit 26534701
Created 3 Jul 2024, 5:24:07 UTC
Sent 3 Jul 2024, 10:23:33 UTC
Report deadline 6 Jul 2024, 10:23:37 UTC
Received 5 Jul 2024, 9:10:20 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 45 min 55 sec
CPU time 1 hours 37 min 37 sec
Validate state Valid
Credit 41.49
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.03 MB
Peak swap size 32.79 GB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Schmidt_666-conf_280.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Schmidt_666-conf_280_0_r1702715779_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Schmidt_666-conf_280_0_r1702715779_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.693934
     * GNaL_b in INaL: 0.005802
     * Gto_b in Ito: 0.086843
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031686
     * GKs_b in IKs: 0.001912
     * GK1_b in IK1: 0.159522
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.463813
     * GKb_b in IKb: 0.003812
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031561
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11467216, states[0] = -55.444604, states[40]= 0.000021
Saving checkpoint... 
Iteration: 22666692, states[0] = -84.668735, states[40]= 0.000001
Saving checkpoint... 
Iteration: 33656928, states[0] = -84.652456, states[40]= 0.000001
Saving checkpoint... 
Iteration: 44035134, states[0] = 26.658610, states[40]= 0.000022
Saving checkpoint... 
Iteration: 54776440, states[0] = -26.668546, states[40]= 0.000201
Saving checkpoint... 
Iteration: 65135827, states[0] = -54.272699, states[40]= 0.000018
Saving checkpoint... 
Iteration: 76458537, states[0] = -42.236087, states[40]= 0.000076
Saving checkpoint... 
Iteration: 87193182, states[0] = -84.084018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98080438, states[0] = 4.032424, states[40]= 0.000189
Saving checkpoint... 
Iteration: 109026794, states[0] = 30.693169, states[40]= 0.001104
Saving checkpoint... 
Iteration: 119084393, states[0] = 2.033218, states[40]= 0.000226
Saving checkpoint... 
Iteration: 129448290, states[0] = -28.487629, states[40]= 0.000192
Saving checkpoint... 
Iteration: 140242666, states[0] = -84.399901, states[40]= 0.000001
Saving checkpoint... 
Iteration: 151196996, states[0] = -84.089994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162161548, states[0] = -79.071818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172584432, states[0] = -84.432138, states[40]= 0.000001
Saving checkpoint... 
Iteration: 182726986, states[0] = 17.978320, states[40]= 0.000024
Saving checkpoint... 
Iteration: 192441618, states[0] = -17.521541, states[40]= 0.000212
Saving checkpoint... 
Iteration: 202821583, states[0] = -68.972506, states[40]= 0.000002
Saving checkpoint... 
Iteration: 213077212, states[0] = 9.579164, states[40]= 0.000094
Saving checkpoint... 
Iteration: 223489121, states[0] = -68.767957, states[40]= 0.000002
Saving checkpoint... 
Iteration: 233761358, states[0] = -1.418201, states[40]= 0.000288
Saving checkpoint... 
Iteration: 243502078, states[0] = -81.286254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253582764, states[0] = -84.403261, states[40]= 0.000001
Saving checkpoint... 
Iteration: 264903641, states[0] = -84.333272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275150303, states[0] = -58.956803, states[40]= 0.000010
Saving checkpoint... 
Iteration: 286021839, states[0] = 29.953601, states[40]= 0.150123
Saving checkpoint... 
Iteration: 296166405, states[0] = -77.286805, states[40]= 0.000001
Saving checkpoint... 
Iteration: 307051075, states[0] = 25.391564, states[40]= 0.000012
Saving checkpoint... 
Iteration: 316181409, states[0] = -83.577478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326389659, states[0] = 23.447263, states[40]= 0.000009
Saving checkpoint... 
Iteration: 337273041, states[0] = -84.486211, states[40]= 0.000001
Saving checkpoint... 
Iteration: 347332946, states[0] = -84.646445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 357832233, states[0] = -72.672055, states[40]= 0.000001
Saving checkpoint... 
Iteration: 368331722, states[0] = -84.641718, states[40]= 0.000001
Saving checkpoint... 
Iteration: 378716736, states[0] = 27.344860, states[40]= 0.000038
Saving checkpoint... 
Iteration: 388666014, states[0] = -84.641149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 399026284, states[0] = 29.725909, states[40]= 0.229582
Saving checkpoint... 
Iteration: 407395774, states[0] = 22.478493, states[40]= 0.000010
Saving checkpoint... 
Iteration: 418140259, states[0] = -40.191784, states[40]= 0.000093
Saving checkpoint... 
Iteration: 428819108, states[0] = -52.743010, states[40]= 0.000022
Saving checkpoint... 
Iteration: 439877359, states[0] = -84.077105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450732831, states[0] = 21.734356, states[40]= 0.000011
Saving checkpoint... 
Iteration: 461870593, states[0] = -84.001740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472783759, states[0] = -11.559143, states[40]= 0.000278
Saving checkpoint... 
Iteration: 483281100, states[0] = -84.485690, states[40]= 0.000001
Saving checkpoint... 
Iteration: 494179213, states[0] = -79.922537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504833612, states[0] = -65.086893, states[40]= 0.000004
Saving checkpoint... 
Iteration: 515859219, states[0] = -83.657067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526324548, states[0] = -84.607120, states[40]= 0.000001
Saving checkpoint... 
Iteration: 537057894, states[0] = 27.385489, states[40]= 0.000039
Saving checkpoint... 
Iteration: 548414717, states[0] = 16.540266, states[40]= 0.000031
Saving checkpoint... 
Iteration: 559324208, states[0] = -84.601811, states[40]= 0.000001
Saving checkpoint... 
Iteration: 570444943, states[0] = -1.480361, states[40]= 0.000287
Saving checkpoint... 
Iteration: 581276681, states[0] = -84.445755, states[40]= 0.000001
Saving checkpoint... 
Iteration: 592752228, states[0] = 15.505429, states[40]= 0.000037
Saving checkpoint... 
Iteration: 602761510, states[0] = 10.654807, states[40]= 0.000081
Saving checkpoint... 
Iteration: 613547799, states[0] = -84.027711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624214380, states[0] = -84.021909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635717710, states[0] = 31.142152, states[40]= 0.002309
Saving checkpoint... 
Iteration: 646303177, states[0] = -84.530589, states[40]= 0.000001
Saving checkpoint... 
Iteration: 657838366, states[0] = -61.576387, states[40]= 0.000007
Saving checkpoint... 
Iteration: 664614899, states[0] = -84.446910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 676065691, states[0] = 27.037280, states[40]= 0.000030
Saving checkpoint... 
Iteration: 687561122, states[0] = -84.111277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698321964, states[0] = -84.576012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 709120960, states[0] = -3.517984, states[40]= 0.000312
Saving checkpoint... 
Iteration: 719753348, states[0] = 18.232239, states[40]= 0.000022
Saving checkpoint... 
Iteration: 730879349, states[0] = -83.937988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742703457, states[0] = -84.666019, states[40]= 0.000001
Saving checkpoint... 
Iteration: 753907508, states[0] = -84.185944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766002975, states[0] = -84.601057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 777044368, states[0] = 29.817871, states[40]= 0.305824
Saving checkpoint... 
Iteration: 788273909, states[0] = -84.379563, states[40]= 0.000001
Saving checkpoint... 
Iteration: 799785869, states[0] = 1.475773, states[40]= 0.000238
Saving checkpoint... 
Iteration: 811161610, states[0] = -41.993064, states[40]= 0.000077
Saving checkpoint... 
Iteration: 822425298, states[0] = 18.155906, states[40]= 0.000023
Saving checkpoint... 
Iteration: 833942122, states[0] = -84.374592, states[40]= 0.000001
Saving checkpoint... 
Iteration: 845183856, states[0] = -64.932447, states[40]= 0.000004
Saving checkpoint... 
Iteration: 856200234, states[0] = -81.689124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866504920, states[0] = -49.740834, states[40]= 0.000032
Saving checkpoint... 
Iteration: 878504172, states[0] = -48.282055, states[40]= 0.000038
Saving checkpoint... 
Iteration: 889646804, states[0] = -84.518898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 901370525, states[0] = -84.650838, states[40]= 0.000001
Saving checkpoint... 
Iteration: 912229122, states[0] = -84.017883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923926863, states[0] = -84.257608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934754070, states[0] = 23.145200, states[40]= 0.000009
Saving checkpoint... 
Iteration: 945835044, states[0] = -42.025963, states[40]= 0.000077
Saving checkpoint... 
Iteration: 957319373, states[0] = -84.525352, states[40]= 0.000001
Saving checkpoint... 
Iteration: 968142161, states[0] = -11.882893, states[40]= 0.000276
Saving checkpoint... 
Iteration: 978966695, states[0] = -84.450949, states[40]= 0.000001
Saving checkpoint... 
Iteration: 989999911, states[0] = -84.560603, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1000823371, states[0] = -26.489654, states[40]= 0.000195
Saving checkpoint... 
Iteration: 1011832875, states[0] = -36.180330, states[40]= 0.000131
Saving checkpoint... 
Iteration: 1022691321, states[0] = -84.614318, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1032786940, states[0] = 8.355967, states[40]= 0.000112
Saving checkpoint... 
Iteration: 1043001246, states[0] = -84.555795, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1053144255, states[0] = -9.501931, states[40]= 0.000301
Saving checkpoint... 
Iteration: 1063995986, states[0] = -84.537241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1074303411, states[0] = -84.443077, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1085263353, states[0] = -84.221147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092064682, states[0] = 30.792132, states[40]= 0.060726
Saving checkpoint... 
Iteration: 1103165488, states[0] = -30.483994, states[40]= 0.000181
Saving checkpoint... 
Iteration: 1114813821, states[0] = -9.303358, states[40]= 0.000303
Saving checkpoint... 
Iteration: 1126615892, states[0] = -84.327597, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1137678249, states[0] = -84.568547, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1148981044, states[0] = -84.470468, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1156594049, states[0] = -84.174763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167302081, states[0] = -84.415159, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1178609439, states[0] = -84.272188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189988001, states[0] = -84.487608, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1201527477, states[0] = -56.107262, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1213190694, states[0] = -51.657279, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1224426858, states[0] = 26.868648, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1236554595, states[0] = -82.461476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247519128, states[0] = -44.508173, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1258795473, states[0] = 9.990081, states[40]= 0.000089
Saving checkpoint... 
Iteration: 1269128261, states[0] = 10.606156, states[40]= 0.000081
Saving checkpoint... 
Iteration: 1279383097, states[0] = -84.631631, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1290828683, states[0] = -16.124457, states[40]= 0.000223
Saving checkpoint... 
Iteration: 1301256273, states[0] = -84.078641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311820149, states[0] = -5.705181, states[40]= 0.000320
Saving checkpoint... 
Iteration: 1322557517, states[0] = -81.946317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333288788, states[0] = -84.299064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343910593, states[0] = -83.931965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354752434, states[0] = 31.347096, states[40]= 0.003568
Saving checkpoint... 
Iteration: 1366017120, states[0] = -84.547724, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1377526913, states[0] = -45.884500, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1388931179, states[0] = -84.108340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398767794, states[0] = 27.330551, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1407651354, states[0] = -84.426715, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1414865627, states[0] = -49.669963, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1427867792, states[0] = -51.314651, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1440980332, states[0] = -84.399034, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1449489582, states[0] = -2.024904, states[40]= 0.000296
Saving checkpoint... 
Iteration: 1459101520, states[0] = 28.365193, states[40]= 0.000088
Saving checkpoint... 
Iteration: 1468672364, states[0] = -84.494246, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1485178756, states[0] = -24.080852, states[40]= 0.000194
Saving checkpoint... 
Iteration: 1498783360, states[0] = 22.637680, states[40]= 0.000010
Total time: 3000150.000000
State Variables:
 - v in component membrane (millivolt): -84.525164
 - CaMKt in component CaMK (millimolar): 0.039306
 - cass in component intracellular_ions (millimolar): 0.000104
 - nai in component intracellular_ions (millimolar): 6.855457
 - nass in component intracellular_ions (millimolar): 6.855613
 - ki in component intracellular_ions (millimolar): 144.803815
 - kss in component intracellular_ions (millimolar): 144.803787
 - cansr in component intracellular_ions (millimolar): 2.063644
 - cajsr in component intracellular_ions (millimolar): 1.817939
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.010284
 - hf in component INa (dimensionless): 0.571365
 - hs in component INa (dimensionless): 0.571207
 - j in component INa (dimensionless): 0.570344
 - hsp in component INa (dimensionless): 0.324444
 - jp in component INa (dimensionless): 0.569631
 - mL in component INaL (dimensionless): 0.000356
 - hL in component INaL (dimensionless): 0.344453
 - hLp in component INaL (dimensionless): 0.149646
 - a in component Ito (dimensionless): 0.001255
 - iF in component Ito (dimensionless): 0.999198
 - iS in component Ito (dimensionless): 0.364632
 - ap in component Ito (dimensionless): 0.000640
 - iFp in component Ito (dimensionless): 0.999198
 - iSp in component Ito (dimensionless): 0.398671
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.842592
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.995726
 - jca in component ICaL (dimensionless): 0.998101
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005937
 - xrf in component IKr (dimensionless): 0.000424
 - xrs in component IKr (dimensionless): 0.674918
 - xs1 in component IKs (dimensionless): 0.386376
 - xs2 in component IKs (dimensionless): 0.000282
 - xk1 in component IK1 (dimensionless): 0.996795
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
05:03:04 (63135): called boinc_finish(0)

</stderr_txt>
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