𝕏

Task 55875613

Name HuVeMOp_20240703071643700359_ORdGradInc_k_26-Coppini_1000-conf_180_0
Workunit 26534441
Created 3 Jul 2024, 5:23:51 UTC
Sent 3 Jul 2024, 10:19:17 UTC
Report deadline 6 Jul 2024, 10:19:17 UTC
Received 5 Jul 2024, 14:50:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224115
Run time 1 hours 3 min 6 sec
CPU time 52 min 41 sec
Validate state Valid
Credit 41.60
Device peak FLOPS 4.81 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.17 MB
Peak swap size 392.01 GB
Peak disk usage 0.70 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Coppini_1000-conf_180.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Coppini_1000-conf_180_0_r157256531_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Coppini_1000-conf_180_0_r157256531_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.917918
     * GNaL_b in INaL: 0.005726
     * Gto_b in Ito: 0.083933
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031787
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.165083
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.927648
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033301
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 34849066, states[0] = -94.909486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65843169, states[0] = -94.893766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97318807, states[0] = -94.863930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133989208, states[0] = -94.964156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163773386, states[0] = -94.788275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193380937, states[0] = -94.919835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226308220, states[0] = -94.847710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257236971, states[0] = -94.695050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290315429, states[0] = -94.857240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321087786, states[0] = -1.697387, states[40]= 0.004336
Saving checkpoint... 
Iteration: 352044245, states[0] = 19.749666, states[40]= 0.002339
Saving checkpoint... 
Iteration: 383694167, states[0] = -94.528284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420030050, states[0] = 24.664910, states[40]= 0.001588
Saving checkpoint... 
Iteration: 447180066, states[0] = -94.292552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478420852, states[0] = -94.940408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509446954, states[0] = -94.950459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531573801, states[0] = 6.896919, states[40]= 0.004494
Saving checkpoint... 
Iteration: 541371074, states[0] = -94.911456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548633161, states[0] = -44.770210, states[40]= 0.000194
Saving checkpoint... 
Iteration: 556824535, states[0] = -94.867534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564382813, states[0] = -94.919489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574135450, states[0] = -47.140026, states[40]= 0.000139
Saving checkpoint... 
Iteration: 584124984, states[0] = -36.602010, states[40]= 0.000545
Saving checkpoint... 
Iteration: 597705632, states[0] = -94.579631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614370839, states[0] = -94.910990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625809138, states[0] = -94.847360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636954039, states[0] = -94.952275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650032168, states[0] = 24.003433, states[40]= 0.001657
Saving checkpoint... 
Iteration: 662377183, states[0] = -94.915320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674408234, states[0] = -94.933653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684727469, states[0] = -94.662444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695135434, states[0] = -47.122766, states[40]= 0.000139
Saving checkpoint... 
Iteration: 707126750, states[0] = -38.329748, states[40]= 0.000446
Saving checkpoint... 
Iteration: 716669136, states[0] = -90.326521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727776039, states[0] = -94.791183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743102150, states[0] = -14.454029, states[40]= 0.001816
Saving checkpoint... 
Iteration: 758263239, states[0] = -94.763460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770338454, states[0] = -94.882079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783868426, states[0] = -94.908512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801664090, states[0] = -83.265425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812995165, states[0] = -94.962172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822085429, states[0] = -0.028289, states[40]= 0.004516
Saving checkpoint... 
Iteration: 837833515, states[0] = -94.876598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854919938, states[0] = -94.938492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872597712, states[0] = -10.119384, states[40]= 0.002638
Saving checkpoint... 
Iteration: 886637422, states[0] = -49.206116, states[40]= 0.000103
Saving checkpoint... 
Iteration: 904073253, states[0] = 7.184764, states[40]= 0.004469
Saving checkpoint... 
Iteration: 921083315, states[0] = 1.376068, states[40]= 0.004609
Saving checkpoint... 
Iteration: 935779038, states[0] = -94.796267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947672098, states[0] = -92.557934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963618716, states[0] = -30.554311, states[40]= 0.000947
Saving checkpoint... 
Iteration: 979208927, states[0] = -94.591748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995577801, states[0] = 4.710565, states[40]= 0.004624
Saving checkpoint... 
Iteration: 1010236111, states[0] = -94.689318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026147844, states[0] = -60.501160, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1040919207, states[0] = -94.937419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060658757, states[0] = -74.543408, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1076738302, states[0] = -94.695793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092035934, states[0] = 22.750718, states[40]= 0.001828
Saving checkpoint... 
Iteration: 1109605421, states[0] = -17.697970, states[40]= 0.001434
Saving checkpoint... 
Iteration: 1124327454, states[0] = -94.868672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137978056, states[0] = -94.957006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169371205, states[0] = -94.909033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199013888, states[0] = 27.749481, states[40]= 0.013778
Saving checkpoint... 
Iteration: 1228332843, states[0] = -94.874299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258233072, states[0] = -94.678691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284898285, states[0] = -94.925932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305684142, states[0] = -94.431310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313292853, states[0] = -94.819652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319755525, states[0] = -94.742570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325816198, states[0] = -94.854073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331771590, states[0] = -94.779591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338992660, states[0] = -94.959544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345739683, states[0] = -94.698873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352858693, states[0] = -94.898506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358813636, states[0] = -94.850565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365760627, states[0] = -94.754878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372946171, states[0] = -94.946734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379591530, states[0] = -4.601008, states[40]= 0.003856
Saving checkpoint... 
Iteration: 1386199556, states[0] = -94.549999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392762730, states[0] = -94.759717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399843285, states[0] = -94.884394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406274060, states[0] = -94.784429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412971245, states[0] = -94.954162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419753010, states[0] = -94.735742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426058926, states[0] = 13.899139, states[40]= 0.003498
Saving checkpoint... 
Iteration: 1433240279, states[0] = -94.700299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440285513, states[0] = -94.806375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447047255, states[0] = 18.608388, states[40]= 0.002559
Saving checkpoint... 
Iteration: 1454486490, states[0] = -94.957732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459881847, states[0] = -94.915265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466270263, states[0] = -94.776230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472965402, states[0] = -94.952324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479584468, states[0] = 0.621461, states[40]= 0.004566
Saving checkpoint... 
Iteration: 1485763603, states[0] = -94.761362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493859364, states[0] = -94.898498, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.836268
 - CaMKt in component CaMK (millimolar): 0.012774
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.736617
 - nass in component intracellular_ions (millimolar): 6.736715
 - ki in component intracellular_ions (millimolar): 145.143005
 - kss in component intracellular_ions (millimolar): 145.142984
 - cansr in component intracellular_ions (millimolar): 1.671908
 - cajsr in component intracellular_ions (millimolar): 1.630251
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003643
 - hf in component INa (dimensionless): 0.878858
 - hs in component INa (dimensionless): 0.878850
 - j in component INa (dimensionless): 0.878800
 - hsp in component INa (dimensionless): 0.723661
 - jp in component INa (dimensionless): 0.878766
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.705744
 - hLp in component INaL (dimensionless): 0.443310
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.612177
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.683197
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.916155
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999835
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003088
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.364665
 - xs1 in component IKs (dimensionless): 0.267121
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997355
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:54:42 (13034): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Coppini_1000-conf_180.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Coppini_1000-conf_180_0_r157256531_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Coppini_1000-conf_180_0_r157256531_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.917918
     * GNaL_b in INaL: 0.005726
     * Gto_b in Ito: 0.083933
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031787
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.165083
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.927648
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033301
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1493859364
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.898498 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.836268
 - CaMKt in component CaMK (millimolar): 0.012774
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.736617
 - nass in component intracellular_ions (millimolar): 6.736715
 - ki in component intracellular_ions (millimolar): 145.143005
 - kss in component intracellular_ions (millimolar): 145.142984
 - cansr in component intracellular_ions (millimolar): 1.671908
 - cajsr in component intracellular_ions (millimolar): 1.630251
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003643
 - hf in component INa (dimensionless): 0.878858
 - hs in component INa (dimensionless): 0.878850
 - j in component INa (dimensionless): 0.878800
 - hsp in component INa (dimensionless): 0.723661
 - jp in component INa (dimensionless): 0.878766
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.705744
 - hLp in component INaL (dimensionless): 0.443310
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.612177
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.683197
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.916155
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999835
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003088
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.364665
 - xs1 in component IKs (dimensionless): 0.267121
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997355
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:58:39 (15226): called boinc_finish(0)

</stderr_txt>
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