𝕏

Task 55873387

Name HuVeMOp_20240703071643700359_ORdGradInc_k_26-Schmidt_575-conf_576_0
Workunit 26533329
Created 3 Jul 2024, 5:22:54 UTC
Sent 3 Jul 2024, 10:07:23 UTC
Report deadline 6 Jul 2024, 10:07:33 UTC
Received 3 Jul 2024, 23:23:30 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224057
Run time 1 hours 59 min 50 sec
CPU time 1 hours 59 min
Validate state Valid
Credit 43.80
Device peak FLOPS 3.39 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.73 MB
Peak swap size 5.35 MB
Peak disk usage 0.19 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Schmidt_575-conf_576.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Schmidt_575-conf_576_0_r795809679_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Schmidt_575-conf_576_0_r795809679_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.889258
     * GNaL_b in INaL: 0.005469
     * Gto_b in Ito: 0.082766
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031716
     * GKs_b in IKs: 0.001961
     * GK1_b in IK1: 0.162207
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.232063
     * GKb_b in IKb: 0.003831
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031037
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 6197797, states[0] = -84.245291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14665816, states[0] = 33.245954, states[40]= 0.595378
Saving checkpoint... 
Iteration: 23122407, states[0] = -48.570876, states[40]= 0.000047
Saving checkpoint... 
Iteration: 31586992, states[0] = -84.650920, states[40]= 0.000001
Saving checkpoint... 
Iteration: 39973255, states[0] = 31.217168, states[40]= 0.048572
Saving checkpoint... 
Iteration: 48462470, states[0] = -83.941369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56889391, states[0] = -84.670587, states[40]= 0.000001
Saving checkpoint... 
Iteration: 65221402, states[0] = -84.652325, states[40]= 0.000001
Saving checkpoint... 
Iteration: 73657381, states[0] = 13.666965, states[40]= 0.000042
Saving checkpoint... 
Iteration: 82164980, states[0] = -84.571192, states[40]= 0.000001
Saving checkpoint... 
Iteration: 90741133, states[0] = -84.225772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99174598, states[0] = -84.748342, states[40]= 0.000001
Saving checkpoint... 
Iteration: 107483871, states[0] = -84.657249, states[40]= 0.000001
Saving checkpoint... 
Iteration: 113754789, states[0] = -84.346553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121926231, states[0] = 29.022072, states[40]= 0.000197
Saving checkpoint... 
Iteration: 130322814, states[0] = -6.938650, states[40]= 0.000296
Saving checkpoint... 
Iteration: 136226699, states[0] = -84.628260, states[40]= 0.000001
Saving checkpoint... 
Iteration: 144684217, states[0] = 4.607486, states[40]= 0.000154
Saving checkpoint... 
Iteration: 153000395, states[0] = 17.514862, states[40]= 0.000020
Saving checkpoint... 
Iteration: 161422283, states[0] = -64.267444, states[40]= 0.000005
Saving checkpoint... 
Iteration: 169754471, states[0] = -57.738014, states[40]= 0.000013
Saving checkpoint... 
Iteration: 177976501, states[0] = 31.614142, states[40]= 0.015261
Saving checkpoint... 
Iteration: 186493750, states[0] = -84.357514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194835428, states[0] = -84.389361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200903038, states[0] = -84.575195, states[40]= 0.000001
Saving checkpoint... 
Iteration: 206798054, states[0] = -7.216545, states[40]= 0.000295
Saving checkpoint... 
Iteration: 214301557, states[0] = -40.239314, states[40]= 0.000094
Saving checkpoint... 
Iteration: 222426219, states[0] = -84.315711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230341652, states[0] = 15.444616, states[40]= 0.000029
Saving checkpoint... 
Iteration: 237821119, states[0] = 12.889991, states[40]= 0.000047
Saving checkpoint... 
Iteration: 245594518, states[0] = 6.104448, states[40]= 0.000128
Saving checkpoint... 
Iteration: 253819006, states[0] = -84.645676, states[40]= 0.000001
Saving checkpoint... 
Iteration: 262065365, states[0] = -82.758184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270398011, states[0] = -80.255938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278762141, states[0] = -84.183299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287169106, states[0] = -84.645144, states[40]= 0.000001
Saving checkpoint... 
Iteration: 295309088, states[0] = 19.539535, states[40]= 0.000013
Saving checkpoint... 
Iteration: 303639302, states[0] = 23.231701, states[40]= 0.000007
Saving checkpoint... 
Iteration: 311870498, states[0] = -84.532312, states[40]= 0.000001
Saving checkpoint... 
Iteration: 320129268, states[0] = -73.510538, states[40]= 0.000001
Saving checkpoint... 
Iteration: 328498111, states[0] = -84.164979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336851659, states[0] = -84.316119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345110874, states[0] = -36.673913, states[40]= 0.000126
Saving checkpoint... 
Iteration: 353444951, states[0] = -32.817666, states[40]= 0.000160
Saving checkpoint... 
Iteration: 361873415, states[0] = -84.388285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370133657, states[0] = -48.184866, states[40]= 0.000041
Saving checkpoint... 
Iteration: 375943389, states[0] = -84.242316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384263600, states[0] = -83.997981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392506769, states[0] = 6.273248, states[40]= 0.000126
Saving checkpoint... 
Iteration: 400699253, states[0] = -84.478225, states[40]= 0.000001
Saving checkpoint... 
Iteration: 408943476, states[0] = -45.172367, states[40]= 0.000058
Saving checkpoint... 
Iteration: 417161555, states[0] = -84.771429, states[40]= 0.000001
Saving checkpoint... 
Iteration: 425400797, states[0] = -84.306341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433794549, states[0] = -84.642775, states[40]= 0.000001
Saving checkpoint... 
Iteration: 442235424, states[0] = 11.828398, states[40]= 0.000056
Saving checkpoint... 
Iteration: 450710106, states[0] = -84.379687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459242928, states[0] = -30.515085, states[40]= 0.000176
Saving checkpoint... 
Iteration: 467638852, states[0] = -84.002867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475995025, states[0] = -84.254443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484544490, states[0] = -32.289811, states[40]= 0.000164
Saving checkpoint... 
Iteration: 492806098, states[0] = 27.040517, states[40]= 0.000037
Saving checkpoint... 
Iteration: 501296768, states[0] = -84.269342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509675640, states[0] = -84.554269, states[40]= 0.000001
Saving checkpoint... 
Iteration: 517982381, states[0] = -84.356939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526295963, states[0] = -84.133349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534707135, states[0] = -84.640262, states[40]= 0.000001
Saving checkpoint... 
Iteration: 542973832, states[0] = -84.166789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551337166, states[0] = -84.392059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559735607, states[0] = -84.696944, states[40]= 0.000001
Saving checkpoint... 
Iteration: 568078429, states[0] = -84.713232, states[40]= 0.000001
Saving checkpoint... 
Iteration: 576265462, states[0] = -41.794391, states[40]= 0.000081
Saving checkpoint... 
Iteration: 584643106, states[0] = -83.373302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592823778, states[0] = -84.765867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 601038012, states[0] = -83.972412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609388917, states[0] = -84.192186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617785695, states[0] = -84.599888, states[40]= 0.000001
Saving checkpoint... 
Iteration: 625965268, states[0] = 0.079229, states[40]= 0.000235
Saving checkpoint... 
Iteration: 634270732, states[0] = 19.989933, states[40]= 0.000012
Saving checkpoint... 
Iteration: 642437552, states[0] = -83.954898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650547380, states[0] = -84.532982, states[40]= 0.000001
Saving checkpoint... 
Iteration: 658772815, states[0] = -36.032996, states[40]= 0.000132
Saving checkpoint... 
Iteration: 667044217, states[0] = 20.772373, states[40]= 0.000010
Saving checkpoint... 
Iteration: 675295467, states[0] = -84.639590, states[40]= 0.000001
Saving checkpoint... 
Iteration: 683644929, states[0] = -84.682998, states[40]= 0.000001
Saving checkpoint... 
Iteration: 692026598, states[0] = 31.622068, states[40]= 0.014735
Saving checkpoint... 
Iteration: 700239348, states[0] = -84.193902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708680543, states[0] = -84.749016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 717117764, states[0] = -15.595914, states[40]= 0.000219
Saving checkpoint... 
Iteration: 725302318, states[0] = -84.556729, states[40]= 0.000001
Saving checkpoint... 
Iteration: 733610123, states[0] = -84.371673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741971201, states[0] = -84.523936, states[40]= 0.000001
Saving checkpoint... 
Iteration: 750135877, states[0] = 18.600897, states[40]= 0.000016
Saving checkpoint... 
Iteration: 758520736, states[0] = -19.186417, states[40]= 0.000192
Saving checkpoint... 
Iteration: 766907027, states[0] = -76.868137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 775060172, states[0] = -84.645356, states[40]= 0.000001
Saving checkpoint... 
Iteration: 783240526, states[0] = -12.893540, states[40]= 0.000248
Saving checkpoint... 
Iteration: 791631610, states[0] = -76.384362, states[40]= 0.000001
Saving checkpoint... 
Iteration: 799815811, states[0] = -84.740875, states[40]= 0.000001
Saving checkpoint... 
Iteration: 808134641, states[0] = -84.686808, states[40]= 0.000001
Saving checkpoint... 
Iteration: 816418760, states[0] = -84.430709, states[40]= 0.000001
Saving checkpoint... 
Iteration: 824669431, states[0] = -46.223003, states[40]= 0.000051
Saving checkpoint... 
Iteration: 832813830, states[0] = -84.478668, states[40]= 0.000001
Saving checkpoint... 
Iteration: 841190894, states[0] = -84.664612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 849381352, states[0] = -31.550163, states[40]= 0.000169
Saving checkpoint... 
Iteration: 857635908, states[0] = 30.011630, states[40]= 0.000533
Saving checkpoint... 
Iteration: 865923088, states[0] = -84.688247, states[40]= 0.000001
Saving checkpoint... 
Iteration: 874178448, states[0] = -84.204658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882388778, states[0] = 17.040310, states[40]= 0.000022
Saving checkpoint... 
Iteration: 890647923, states[0] = -84.687017, states[40]= 0.000001
Saving checkpoint... 
Iteration: 899055485, states[0] = 21.403275, states[40]= 0.000009
Saving checkpoint... 
Iteration: 907174221, states[0] = -37.598615, states[40]= 0.000118
Saving checkpoint... 
Iteration: 915515366, states[0] = -41.671802, states[40]= 0.000082
Saving checkpoint... 
Iteration: 923919355, states[0] = -84.235342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932180955, states[0] = -31.095252, states[40]= 0.000172
Saving checkpoint... 
Iteration: 940357188, states[0] = -84.574491, states[40]= 0.000001
Saving checkpoint... 
Iteration: 948693357, states[0] = -84.567884, states[40]= 0.000001
Saving checkpoint... 
Iteration: 956867456, states[0] = 7.475351, states[40]= 0.000107
Saving checkpoint... 
Iteration: 965180209, states[0] = 21.543813, states[40]= 0.000009
Saving checkpoint... 
Iteration: 973507798, states[0] = 26.296571, states[40]= 0.000022
Saving checkpoint... 
Iteration: 981782017, states[0] = -84.673194, states[40]= 0.000001
Saving checkpoint... 
Iteration: 989883106, states[0] = 30.823206, states[40]= 0.001441
Saving checkpoint... 
Iteration: 998141480, states[0] = -84.557295, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1006385543, states[0] = -65.196669, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1014502110, states[0] = -84.396356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020330800, states[0] = -84.740890, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1028691186, states[0] = 31.581422, states[40]= 0.006974
Saving checkpoint... 
Iteration: 1037006541, states[0] = -84.742232, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1045168480, states[0] = -31.118900, states[40]= 0.000172
Saving checkpoint... 
Iteration: 1053475015, states[0] = 2.234334, states[40]= 0.000197
Saving checkpoint... 
Iteration: 1061874202, states[0] = -66.703135, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1070146523, states[0] = 4.751074, states[40]= 0.000151
Saving checkpoint... 
Iteration: 1078428042, states[0] = 31.620815, states[40]= 0.008782
Saving checkpoint... 
Iteration: 1086646849, states[0] = -84.253107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094999652, states[0] = -84.376322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103279511, states[0] = -73.752268, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1111635157, states[0] = -83.826334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120119243, states[0] = 31.137557, states[40]= 0.002341
Saving checkpoint... 
Iteration: 1126174078, states[0] = 24.553404, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1134369732, states[0] = -84.232688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142652571, states[0] = -55.460842, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1151220021, states[0] = 5.781074, states[40]= 0.000134
Saving checkpoint... 
Iteration: 1159640471, states[0] = -82.744671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168183464, states[0] = 5.138923, states[40]= 0.000144
Saving checkpoint... 
Iteration: 1176641599, states[0] = -84.311912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185092705, states[0] = 31.411559, states[40]= 0.004052
Saving checkpoint... 
Iteration: 1193685169, states[0] = -84.714921, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1202368754, states[0] = 21.015445, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1210970400, states[0] = 30.876726, states[40]= 0.001550
Saving checkpoint... 
Iteration: 1219395961, states[0] = -33.922158, states[40]= 0.000151
Saving checkpoint... 
Iteration: 1227742172, states[0] = -43.675035, states[40]= 0.000067
Saving checkpoint... 
Iteration: 1236338740, states[0] = -10.762279, states[40]= 0.000270
Saving checkpoint... 
Iteration: 1244746307, states[0] = -83.727164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253163213, states[0] = -84.593049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1261649329, states[0] = -23.434724, states[40]= 0.000185
Saving checkpoint... 
Iteration: 1270051468, states[0] = -83.981380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275829089, states[0] = -84.308968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284135369, states[0] = -83.833050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292512179, states[0] = -84.370839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300775345, states[0] = -52.886138, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1309131939, states[0] = -76.717167, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1317447717, states[0] = -49.897641, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1325760540, states[0] = -21.912045, states[40]= 0.000185
Saving checkpoint... 
Iteration: 1334051934, states[0] = 16.686949, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1342327334, states[0] = -84.723124, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1350527988, states[0] = -71.724107, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1358861208, states[0] = -66.032780, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1367208022, states[0] = -77.900457, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1372925544, states[0] = -39.057960, states[40]= 0.000104
Saving checkpoint... 
Iteration: 1381131283, states[0] = -84.698718, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1389464324, states[0] = -84.685221, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1397645242, states[0] = -33.102353, states[40]= 0.000158
Saving checkpoint... 
Iteration: 1405884357, states[0] = 30.752532, states[40]= 0.080628
Saving checkpoint... 
Iteration: 1414221464, states[0] = 30.629432, states[40]= 0.092798
Saving checkpoint... 
Iteration: 1422668224, states[0] = -44.842437, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1430793434, states[0] = -84.319274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439007005, states[0] = 6.133031, states[40]= 0.000128
Saving checkpoint... 
Iteration: 1447125469, states[0] = -68.347670, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1455333163, states[0] = 30.378673, states[40]= 0.123521
Saving checkpoint... 
Iteration: 1463610914, states[0] = -84.576867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1471973974, states[0] = -84.673989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1480184359, states[0] = -63.645469, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1488466058, states[0] = -0.549399, states[40]= 0.000245
Saving checkpoint... 
Iteration: 1496662693, states[0] = -84.523836, states[40]= 0.000001
Total time: 3000350.000000
State Variables:
 - v in component membrane (millivolt): -84.618946
 - CaMKt in component CaMK (millimolar): 0.056018
 - cass in component intracellular_ions (millimolar): 0.000111
 - nai in component intracellular_ions (millimolar): 6.883613
 - nass in component intracellular_ions (millimolar): 6.883789
 - ki in component intracellular_ions (millimolar): 144.701707
 - kss in component intracellular_ions (millimolar): 144.701678
 - cansr in component intracellular_ions (millimolar): 2.233036
 - cajsr in component intracellular_ions (millimolar): 1.851142
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.010188
 - hf in component INa (dimensionless): 0.575135
 - hs in component INa (dimensionless): 0.574892
 - j in component INa (dimensionless): 0.573521
 - hsp in component INa (dimensionless): 0.327578
 - jp in component INa (dimensionless): 0.571995
 - mL in component INaL (dimensionless): 0.000350
 - hL in component INaL (dimensionless): 0.321122
 - hLp in component INaL (dimensionless): 0.136614
 - a in component Ito (dimensionless): 0.001247
 - iF in component Ito (dimensionless): 0.999210
 - iS in component Ito (dimensionless): 0.305363
 - ap in component Ito (dimensionless): 0.000635
 - iFp in component Ito (dimensionless): 0.999210
 - iSp in component Ito (dimensionless): 0.335988
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.813139
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.990387
 - jca in component ICaL (dimensionless): 0.994326
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.007781
 - xrf in component IKr (dimensionless): 0.001982
 - xrs in component IKr (dimensionless): 0.727308
 - xs1 in component IKs (dimensionless): 0.425711
 - xs2 in component IKs (dimensionless): 0.000288
 - xk1 in component IK1 (dimensionless): 0.996774
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
01:08:04 (19412): called boinc_finish(0)

</stderr_txt>
]]>


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