𝕏

Task 55873288

Name HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_976_1
Workunit 26533279
Created 3 Jul 2024, 5:22:48 UTC
Sent 3 Jul 2024, 10:05:48 UTC
Report deadline 6 Jul 2024, 19:41:48 UTC
Received 4 Jul 2024, 0:06:55 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240887
Run time 2 hours 51 min 16 sec
CPU time 1 hours 48 min 27 sec
Validate state Valid
Credit 68.76
Device peak FLOPS 5.07 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.63 MB
Peak swap size 3.82 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_976.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_976_1_r1642844721_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_976_1_r1642844721_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.632479
     * GNaL_b in INaL: 0.006069
     * Gto_b in Ito: 0.087126
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031364
     * GKs_b in IKs: 0.001909
     * GK1_b in IK1: 0.167355
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.918076
     * GKb_b in IKb: 0.003812
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036920
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12462538, states[0] = -95.136360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25146913, states[0] = -70.826534, states[40]= 0.000001
Saving checkpoint... 
Iteration: 37865336, states[0] = -95.061104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50433021, states[0] = -95.069622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62936923, states[0] = -95.062959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75077030, states[0] = -0.399103, states[40]= 0.004168
Saving checkpoint... 
Iteration: 87238474, states[0] = -94.932673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99377124, states[0] = -95.035913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111566561, states[0] = 5.081074, states[40]= 0.004682
Saving checkpoint... 
Iteration: 123619303, states[0] = -35.997882, states[40]= 0.000230
Saving checkpoint... 
Iteration: 135937960, states[0] = -95.048919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148056016, states[0] = 9.575436, states[40]= 0.004859
Saving checkpoint... 
Iteration: 160070543, states[0] = 3.291828, states[40]= 0.004555
Saving checkpoint... 
Iteration: 172475796, states[0] = -95.054158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185063184, states[0] = 6.644160, states[40]= 0.004758
Saving checkpoint... 
Iteration: 197657298, states[0] = -81.551469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210179558, states[0] = -94.791825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222846699, states[0] = -95.017956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235623154, states[0] = -39.551281, states[40]= 0.000140
Saving checkpoint... 
Iteration: 248290973, states[0] = -94.982386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261310998, states[0] = -94.997407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273736699, states[0] = -94.922134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285877758, states[0] = -95.030651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298341943, states[0] = -95.015454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310564227, states[0] = 6.203052, states[40]= 0.004738
Saving checkpoint... 
Iteration: 322718357, states[0] = -94.893129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335067354, states[0] = 4.811005, states[40]= 0.004662
Saving checkpoint... 
Iteration: 347369818, states[0] = -95.027660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359363331, states[0] = -95.025085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371615892, states[0] = -32.599321, states[40]= 0.000356
Saving checkpoint... 
Iteration: 384312483, states[0] = -94.998284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396845777, states[0] = -95.017262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409403266, states[0] = -95.038621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421940684, states[0] = -95.047461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434381634, states[0] = -95.031889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447050156, states[0] = 11.863970, states[40]= 0.004928
Saving checkpoint... 
Iteration: 459750499, states[0] = -94.940581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472458027, states[0] = -95.050594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484724107, states[0] = -94.902634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496509652, states[0] = 23.038562, states[40]= 0.057570
Saving checkpoint... 
Iteration: 508767619, states[0] = -94.960268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520805305, states[0] = -94.993220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532738256, states[0] = -94.924166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544791727, states[0] = -94.982753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557013840, states[0] = 22.166183, states[40]= 0.022927
Saving checkpoint... 
Iteration: 568576935, states[0] = 0.004543, states[40]= 0.004210
Saving checkpoint... 
Iteration: 580798084, states[0] = -94.987801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593428180, states[0] = -95.044729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606140480, states[0] = -57.854202, states[40]= 0.000008
Saving checkpoint... 
Iteration: 618511810, states[0] = 22.495864, states[40]= 0.035022
Saving checkpoint... 
Iteration: 631293671, states[0] = -94.984283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644290098, states[0] = -94.981336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656810819, states[0] = -94.996987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669778042, states[0] = -94.970579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681950399, states[0] = -95.049131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694376250, states[0] = -95.029829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706202530, states[0] = -94.863892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718456594, states[0] = -95.050195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730545680, states[0] = 13.529170, states[40]= 0.005007
Saving checkpoint... 
Iteration: 742511086, states[0] = 22.643059, states[40]= 0.041224
Saving checkpoint... 
Iteration: 754818330, states[0] = -95.001846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767037963, states[0] = 16.264062, states[40]= 0.005293
Saving checkpoint... 
Iteration: 779458185, states[0] = -95.050425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792170987, states[0] = -94.386806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804839332, states[0] = -95.013791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817306354, states[0] = -94.993780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830027080, states[0] = 19.586253, states[40]= 0.006514
Saving checkpoint... 
Iteration: 842484717, states[0] = -95.054330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855357183, states[0] = -95.022183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867734200, states[0] = -94.918070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879746825, states[0] = -94.935611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892020424, states[0] = 21.105979, states[40]= 0.009289
Saving checkpoint... 
Iteration: 904250031, states[0] = -94.939707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916488121, states[0] = -95.054721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928715277, states[0] = -94.887377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940647120, states[0] = -65.795497, states[40]= 0.000002
Saving checkpoint... 
Iteration: 952685013, states[0] = -94.823943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964748481, states[0] = -94.937697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977191260, states[0] = -94.840653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989597284, states[0] = -15.335629, states[40]= 0.001409
Saving checkpoint... 
Iteration: 1002355158, states[0] = -95.021205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014769576, states[0] = -94.961985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027464139, states[0] = -95.051240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039603117, states[0] = -20.727695, states[40]= 0.000923
Saving checkpoint... 
Iteration: 1052188043, states[0] = -94.832923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065199959, states[0] = -94.858622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077410715, states[0] = -95.040210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089598657, states[0] = -16.598850, states[40]= 0.001259
Saving checkpoint... 
Iteration: 1102073682, states[0] = 1.749890, states[40]= 0.004414
Saving checkpoint... 
Iteration: 1114218741, states[0] = -94.893271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126065329, states[0] = 5.720356, states[40]= 0.004714
Saving checkpoint... 
Iteration: 1138003508, states[0] = 33.876893, states[40]= 0.148243
Saving checkpoint... 
Iteration: 1150079207, states[0] = -1.305408, states[40]= 0.004025
Saving checkpoint... 
Iteration: 1162108710, states[0] = -25.904889, states[40]= 0.000673
Saving checkpoint... 
Iteration: 1174730723, states[0] = -94.912641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187460094, states[0] = -95.050483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200122018, states[0] = -38.436285, states[40]= 0.000164
Saving checkpoint... 
Iteration: 1212508612, states[0] = 23.478875, states[40]= 0.073544
Saving checkpoint... 
Iteration: 1224796314, states[0] = -94.986010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237326887, states[0] = -95.006717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249828019, states[0] = -95.007362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262164781, states[0] = -92.058994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274681485, states[0] = -94.806898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286438480, states[0] = -95.046469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298527295, states[0] = 19.529639, states[40]= 0.006470
Saving checkpoint... 
Iteration: 1310440657, states[0] = -95.046889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322581844, states[0] = -2.939243, states[40]= 0.003755
Saving checkpoint... 
Iteration: 1334811980, states[0] = -94.997339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346795137, states[0] = -94.985001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359170284, states[0] = -94.281778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371786158, states[0] = -94.977505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384187872, states[0] = -94.832262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396899077, states[0] = -95.036794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409381445, states[0] = -95.031203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422022513, states[0] = 20.680891, states[40]= 0.007990
Saving checkpoint... 
Iteration: 1434630786, states[0] = -47.293595, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1446755322, states[0] = -94.945859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459237534, states[0] = -94.922542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471827714, states[0] = -95.007045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483738685, states[0] = -94.924164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495778076, states[0] = -94.970083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507815414, states[0] = 22.496510, states[40]= 0.019517
Saving checkpoint... 
Iteration: 1519586997, states[0] = -20.322704, states[40]= 0.001010
Saving checkpoint... 
Iteration: 1531351694, states[0] = -94.928749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543363572, states[0] = -95.114902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555737075, states[0] = -95.260104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567820995, states[0] = 20.575249, states[40]= 0.010201
Saving checkpoint... 
Iteration: 1580255238, states[0] = -95.078632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592702728, states[0] = 39.902564, states[40]= 0.099112
Saving checkpoint... 
Iteration: 1605185559, states[0] = -95.185243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617422854, states[0] = -63.740445, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1629938556, states[0] = 13.484264, states[40]= 0.006119
Saving checkpoint... 
Iteration: 1642529633, states[0] = 17.386933, states[40]= 0.007081
Saving checkpoint... 
Iteration: 1655135183, states[0] = 15.018500, states[40]= 0.006390
Saving checkpoint... 
Iteration: 1667620033, states[0] = -95.249073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1680252101, states[0] = -95.288842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1692437015, states[0] = -87.627555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1704659714, states[0] = 2.254555, states[40]= 0.005061
Saving checkpoint... 
Iteration: 1716914195, states[0] = 22.388541, states[40]= 0.023064
Saving checkpoint... 
Iteration: 1729024969, states[0] = -66.845112, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1740952452, states[0] = 6.460671, states[40]= 0.005449
Saving checkpoint... 
Iteration: 1753095325, states[0] = -95.207456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765325988, states[0] = -68.347933, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1777437792, states[0] = -95.272995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1789809516, states[0] = 23.913464, states[40]= 0.059145
Saving checkpoint... 
Iteration: 1802343808, states[0] = -95.073411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814948165, states[0] = -95.090108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827529276, states[0] = 18.626404, states[40]= 0.006074
Saving checkpoint... 
Iteration: 1840001848, states[0] = 45.824782, states[40]= 0.082265
Saving checkpoint... 
Iteration: 1852562784, states[0] = 6.509993, states[40]= 0.004764
Saving checkpoint... 
Iteration: 1865013683, states[0] = 22.114147, states[40]= 0.023570
Saving checkpoint... 
Iteration: 1877645660, states[0] = -64.596215, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1890503796, states[0] = 32.394967, states[40]= 0.153464
Saving checkpoint... 
Iteration: 1902889283, states[0] = -95.036629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1915170663, states[0] = -94.367949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927301371, states[0] = -94.990950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939636503, states[0] = -53.517126, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1952211288, states[0] = -94.880282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1964592351, states[0] = -10.943990, states[40]= 0.002124
Saving checkpoint... 
Iteration: 1977704872, states[0] = -94.867889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989882751, states[0] = -95.031468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002597456, states[0] = -15.502540, states[40]= 0.001388
Saving checkpoint... 
Iteration: 2016192446, states[0] = -94.842650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029694054, states[0] = -94.846030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2043473328, states[0] = -95.051986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2056787785, states[0] = -94.978452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070418666, states[0] = -95.041546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083884264, states[0] = -95.031688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096865515, states[0] = -95.024811, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.931220
 - CaMKt in component CaMK (millimolar): 0.007001
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.567002
 - nass in component intracellular_ions (millimolar): 6.567062
 - ki in component intracellular_ions (millimolar): 145.410907
 - kss in component intracellular_ions (millimolar): 145.410888
 - cansr in component intracellular_ions (millimolar): 1.310422
 - cajsr in component intracellular_ions (millimolar): 1.272183
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003608
 - hf in component INa (dimensionless): 0.880509
 - hs in component INa (dimensionless): 0.880505
 - j in component INa (dimensionless): 0.880477
 - hsp in component INa (dimensionless): 0.726790
 - jp in component INa (dimensionless): 0.880458
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710222
 - hLp in component INaL (dimensionless): 0.451484
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.619193
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.693752
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934123
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001594
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332682
 - xs1 in component IKs (dimensionless): 0.244922
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997329
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:06:42 (680380): called boinc_finish(0)

</stderr_txt>
]]>


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