𝕏

Task 55872016

Name HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_3000-conf_674_1
Workunit 26532644
Created 3 Jul 2024, 5:22:17 UTC
Sent 3 Jul 2024, 9:57:27 UTC
Report deadline 6 Jul 2024, 9:57:27 UTC
Received 3 Jul 2024, 18:55:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235353
Run time 3 hours 2 min 43 sec
CPU time 2 hours 0 min 27 sec
Validate state Valid
Credit 46.78
Device peak FLOPS 4.99 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.19 MB
Peak swap size 5.27 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_3000-conf_674.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_3000-conf_674_1_r1940977742_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_3000-conf_674_1_r1940977742_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.455627
     * GNaL_b in INaL: 0.006040
     * Gto_b in Ito: 0.087449
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031691
     * GKs_b in IKs: 0.001960
     * GK1_b in IK1: 0.161241
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.417253
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031455
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9505338, states[0] = -94.184155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18717573, states[0] = -94.238944, states[40]= 0.000001
Saving checkpoint... 
Iteration: 27168082, states[0] = -8.275662, states[40]= 0.001033
Saving checkpoint... 
Iteration: 35702778, states[0] = -94.240326, states[40]= 0.000001
Saving checkpoint... 
Iteration: 44068114, states[0] = -94.228454, states[40]= 0.000001
Saving checkpoint... 
Iteration: 53372097, states[0] = -94.270236, states[40]= 0.000001
Saving checkpoint... 
Iteration: 61769709, states[0] = -73.573155, states[40]= 0.000021
Saving checkpoint... 
Iteration: 70065790, states[0] = -94.276090, states[40]= 0.000001
Saving checkpoint... 
Iteration: 78407620, states[0] = -94.106330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86914959, states[0] = -94.271415, states[40]= 0.000001
Saving checkpoint... 
Iteration: 96420766, states[0] = -94.140308, states[40]= 0.000001
Saving checkpoint... 
Iteration: 104897833, states[0] = -94.278294, states[40]= 0.000001
Saving checkpoint... 
Iteration: 113458688, states[0] = -94.297803, states[40]= 0.000001
Saving checkpoint... 
Iteration: 122010606, states[0] = -94.244299, states[40]= 0.000001
Saving checkpoint... 
Iteration: 131275392, states[0] = -94.304161, states[40]= 0.000001
Saving checkpoint... 
Iteration: 139860331, states[0] = -94.016426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148128182, states[0] = -94.295548, states[40]= 0.000001
Saving checkpoint... 
Iteration: 156262088, states[0] = -79.186472, states[40]= 0.000010
Saving checkpoint... 
Iteration: 164572851, states[0] = -94.298857, states[40]= 0.000001
Saving checkpoint... 
Iteration: 173844141, states[0] = -94.288323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 182375920, states[0] = -94.306664, states[40]= 0.000001
Saving checkpoint... 
Iteration: 190626972, states[0] = 4.360991, states[40]= 0.000233
Saving checkpoint... 
Iteration: 199056702, states[0] = -94.300275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 207550738, states[0] = -94.271460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 217042733, states[0] = -94.300872, states[40]= 0.000001
Saving checkpoint... 
Iteration: 225313686, states[0] = -93.838453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233793830, states[0] = -94.290475, states[40]= 0.000001
Saving checkpoint... 
Iteration: 242321193, states[0] = -94.307568, states[40]= 0.000001
Saving checkpoint... 
Iteration: 252012171, states[0] = 30.134955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260388341, states[0] = -94.306122, states[40]= 0.000001
Saving checkpoint... 
Iteration: 268776203, states[0] = -93.355363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277189278, states[0] = -94.294012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 285848556, states[0] = -94.306606, states[40]= 0.000001
Saving checkpoint... 
Iteration: 297267569, states[0] = -89.290616, states[40]= 0.000002
Saving checkpoint... 
Iteration: 308137813, states[0] = -94.295452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 318987594, states[0] = -94.301726, states[40]= 0.000001
Saving checkpoint... 
Iteration: 330012109, states[0] = 30.102727, states[40]= -0.000000
Saving checkpoint... 
Iteration: 341270206, states[0] = -94.305720, states[40]= 0.000001
Saving checkpoint... 
Iteration: 350238232, states[0] = -94.304608, states[40]= 0.000001
Saving checkpoint... 
Iteration: 358545055, states[0] = 32.502831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367190388, states[0] = -94.292364, states[40]= 0.000001
Saving checkpoint... 
Iteration: 375765232, states[0] = -94.304978, states[40]= 0.000001
Saving checkpoint... 
Iteration: 385005531, states[0] = -94.299781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 393391815, states[0] = -94.098864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400808326, states[0] = -93.808554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409415808, states[0] = -94.283182, states[40]= 0.000001
Saving checkpoint... 
Iteration: 417885678, states[0] = -94.303379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 427189897, states[0] = -94.291254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 435684788, states[0] = -94.299376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444166944, states[0] = -16.064201, states[40]= 0.001347
Saving checkpoint... 
Iteration: 452716673, states[0] = -94.289681, states[40]= 0.000001
Saving checkpoint... 
Iteration: 461215011, states[0] = -94.301309, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470650807, states[0] = -94.292051, states[40]= 0.000001
Saving checkpoint... 
Iteration: 478863372, states[0] = -94.025709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487329233, states[0] = -94.284710, states[40]= 0.000001
Saving checkpoint... 
Iteration: 495811660, states[0] = -94.303098, states[40]= 0.000001
Saving checkpoint... 
Iteration: 505324272, states[0] = -94.284550, states[40]= 0.000001
Saving checkpoint... 
Iteration: 513944457, states[0] = -94.299700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 522560717, states[0] = -94.270407, states[40]= 0.000001
Saving checkpoint... 
Iteration: 531282522, states[0] = -93.626203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539466116, states[0] = -94.298414, states[40]= 0.000001
Saving checkpoint... 
Iteration: 549215318, states[0] = -38.029221, states[40]= 0.003298
Saving checkpoint... 
Iteration: 557932824, states[0] = -94.279810, states[40]= 0.000001
Saving checkpoint... 
Iteration: 566586508, states[0] = -94.292950, states[40]= 0.000001
Saving checkpoint... 
Iteration: 575125353, states[0] = -94.288095, states[40]= 0.000001
Saving checkpoint... 
Iteration: 583750163, states[0] = -64.854416, states[40]= 0.000082
Saving checkpoint... 
Iteration: 593190108, states[0] = -94.296896, states[40]= 0.000001
Saving checkpoint... 
Iteration: 601711347, states[0] = -35.626706, states[40]= 0.004205
Saving checkpoint... 
Iteration: 610213251, states[0] = -94.286833, states[40]= 0.000001
Saving checkpoint... 
Iteration: 618775855, states[0] = -94.300573, states[40]= 0.000001
Saving checkpoint... 
Iteration: 628356217, states[0] = -94.281068, states[40]= 0.000001
Saving checkpoint... 
Iteration: 636860618, states[0] = -94.299819, states[40]= 0.000001
Saving checkpoint... 
Iteration: 645460641, states[0] = -94.200265, states[40]= 0.000001
Saving checkpoint... 
Iteration: 654723932, states[0] = -94.298164, states[40]= 0.000001
Saving checkpoint... 
Iteration: 663851063, states[0] = -94.299487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 673962621, states[0] = -94.201821, states[40]= 0.000001
Saving checkpoint... 
Iteration: 683018459, states[0] = -94.246554, states[40]= 0.000001
Saving checkpoint... 
Iteration: 691953329, states[0] = -94.191292, states[40]= 0.000001
Saving checkpoint... 
Iteration: 701008210, states[0] = -94.239713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 710939527, states[0] = -94.276699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 719441023, states[0] = -94.295936, states[40]= 0.000001
Saving checkpoint... 
Iteration: 727888891, states[0] = -94.086051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736350592, states[0] = -94.279226, states[40]= 0.000001
Saving checkpoint... 
Iteration: 744880521, states[0] = -94.297325, states[40]= 0.000001
Saving checkpoint... 
Iteration: 754260057, states[0] = -94.282256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 762890154, states[0] = -94.296728, states[40]= 0.000001
Saving checkpoint... 
Iteration: 771289020, states[0] = -93.687910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779768175, states[0] = -94.281458, states[40]= 0.000001
Saving checkpoint... 
Iteration: 788178497, states[0] = -94.292057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 797774902, states[0] = -94.280857, states[40]= 0.000001
Saving checkpoint... 
Iteration: 806316062, states[0] = -94.297203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 814733345, states[0] = -50.799462, states[40]= 0.000672
Saving checkpoint... 
Iteration: 823257444, states[0] = -94.281049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 832754344, states[0] = -69.345980, states[40]= 0.000041
Saving checkpoint... 
Iteration: 841337491, states[0] = -94.277701, states[40]= 0.000001
Saving checkpoint... 
Iteration: 849843281, states[0] = -94.296096, states[40]= 0.000001
Saving checkpoint... 
Iteration: 858504173, states[0] = -94.233968, states[40]= 0.000001
Saving checkpoint... 
Iteration: 866884835, states[0] = -94.275554, states[40]= 0.000001
Saving checkpoint... 
Iteration: 876529726, states[0] = -94.249303, states[40]= 0.000001
Saving checkpoint... 
Iteration: 885171847, states[0] = -18.574650, states[40]= 0.002186
Saving checkpoint... 
Iteration: 893741070, states[0] = -94.280351, states[40]= 0.000001
Saving checkpoint... 
Iteration: 902315911, states[0] = -94.295386, states[40]= 0.000001
Saving checkpoint... 
Iteration: 911919568, states[0] = -94.273532, states[40]= 0.000001
Saving checkpoint... 
Iteration: 922596314, states[0] = 16.301143, states[40]= 0.000016
Saving checkpoint... 
Iteration: 933535098, states[0] = -94.251039, states[40]= 0.000001
Saving checkpoint... 
Iteration: 944288793, states[0] = -94.294560, states[40]= 0.000001
Saving checkpoint... 
Iteration: 955023219, states[0] = -94.288261, states[40]= 0.000001
Saving checkpoint... 
Iteration: 965824804, states[0] = -94.275799, states[40]= 0.000001
Saving checkpoint... 
Iteration: 974432411, states[0] = -94.291400, states[40]= 0.000001
Saving checkpoint... 
Iteration: 982805030, states[0] = -93.779633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991191667, states[0] = -94.280491, states[40]= 0.000001
Saving checkpoint... 
Iteration: 999591496, states[0] = -94.271821, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1008958309, states[0] = -94.289815, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1017618226, states[0] = -94.278214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1026267430, states[0] = -89.059605, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1034652128, states[0] = -94.281306, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1044226685, states[0] = -45.785342, states[40]= 0.001319
Saving checkpoint... 
Iteration: 1052793934, states[0] = -94.275293, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1061416370, states[0] = -94.290286, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1069936345, states[0] = -94.162786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1078507879, states[0] = 27.195248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087735155, states[0] = -52.175500, states[40]= 0.000553
Saving checkpoint... 
Iteration: 1096046062, states[0] = -94.284631, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1104353940, states[0] = -93.984666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112624209, states[0] = -94.281003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1121836282, states[0] = -94.272423, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1130272627, states[0] = -94.290833, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1138955733, states[0] = -94.185478, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1147479727, states[0] = -94.267149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1156005494, states[0] = -94.285183, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1165379613, states[0] = -94.270075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1174060315, states[0] = -94.282559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1182564270, states[0] = -94.259269, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1191108312, states[0] = 11.673500, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1200512189, states[0] = -94.232818, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1211512890, states[0] = -94.283832, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1222323428, states[0] = -94.270993, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1232921211, states[0] = -94.267394, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1243031872, states[0] = -94.282448, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1253799228, states[0] = -94.271290, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1262181117, states[0] = -94.283351, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1270742061, states[0] = -57.625247, states[40]= 0.000247
Saving checkpoint... 
Iteration: 1279267788, states[0] = -94.272002, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1287695014, states[0] = -94.284175, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1296867854, states[0] = -94.287171, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1305400921, states[0] = -94.100091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1313896028, states[0] = -94.266696, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1322490266, states[0] = -94.282642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1331923964, states[0] = -94.265423, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1340647368, states[0] = -94.275710, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1349124132, states[0] = -94.273179, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1357682846, states[0] = -23.007177, states[40]= 0.005494
Saving checkpoint... 
Iteration: 1365967626, states[0] = -94.282702, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1375162995, states[0] = -94.274401, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1383697749, states[0] = -94.282585, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1392322912, states[0] = -93.860097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401002253, states[0] = 24.720237, states[40]= 1.690697
Saving checkpoint... 
Iteration: 1410499186, states[0] = -94.219913, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1418988807, states[0] = -94.261725, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1427513613, states[0] = -94.279706, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1435961475, states[0] = -94.186083, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1444552669, states[0] = 30.944701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453951953, states[0] = -94.175151, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1462379288, states[0] = -94.264450, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1470851197, states[0] = -94.284204, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1479253638, states[0] = -68.460967, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1488493036, states[0] = -94.213800, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1497066518, states[0] = 27.015167, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.135809
 - CaMKt in component CaMK (millimolar): 0.004540
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 7.919568
 - nass in component intracellular_ions (millimolar): 7.919734
 - ki in component intracellular_ions (millimolar): 143.788322
 - kss in component intracellular_ions (millimolar): 143.788303
 - cansr in component intracellular_ions (millimolar): 1.940803
 - cajsr in component intracellular_ions (millimolar): 1.943160
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.003909
 - hf in component INa (dimensionless): 0.866059
 - hs in component INa (dimensionless): 0.866060
 - j in component INa (dimensionless): 0.866068
 - hsp in component INa (dimensionless): 0.700117
 - jp in component INa (dimensionless): 0.866072
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708580
 - hLp in component INaL (dimensionless): 0.510205
 - a in component Ito (dimensionless): 0.000657
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.964014
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.981206
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.985629
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004952
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.034129
 - xs1 in component IKs (dimensionless): 0.093741
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997531
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
20:37:28 (17588): called boinc_finish(0)

</stderr_txt>
]]>


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