𝕏

Task 55867838

Name HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_3000-conf_556_0
Workunit 26530556
Created 3 Jul 2024, 5:20:23 UTC
Sent 3 Jul 2024, 9:21:21 UTC
Report deadline 6 Jul 2024, 9:21:21 UTC
Received 5 Jul 2024, 9:10:20 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 45 min 51 sec
CPU time 1 hours 38 min 8 sec
Validate state Valid
Credit 42.89
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.03 MB
Peak swap size 32.91 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_3000-conf_556.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_3000-conf_556_0_r29565618_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_3000-conf_556_0_r29565618_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.083251
     * GNaL_b in INaL: 0.006151
     * Gto_b in Ito: 0.082028
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032207
     * GKs_b in IKs: 0.001973
     * GK1_b in IK1: 0.163798
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 71.327838
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033446
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 6648231, states[0] = -94.287442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17170414, states[0] = -94.263519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27245399, states[0] = -41.528986, states[40]= 0.002036
Saving checkpoint... 
Iteration: 37626552, states[0] = 7.209090, states[40]= 0.000125
Saving checkpoint... 
Iteration: 48045361, states[0] = 33.389964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58180273, states[0] = -94.289223, states[40]= 0.000001
Saving checkpoint... 
Iteration: 68664730, states[0] = -94.297224, states[40]= 0.000001
Saving checkpoint... 
Iteration: 78677089, states[0] = -94.308500, states[40]= 0.000001
Saving checkpoint... 
Iteration: 88004956, states[0] = -94.313548, states[40]= 0.000001
Saving checkpoint... 
Iteration: 99089823, states[0] = 19.036556, states[40]= 0.000007
Saving checkpoint... 
Iteration: 109217692, states[0] = -94.311623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 119558917, states[0] = -94.320072, states[40]= 0.000001
Saving checkpoint... 
Iteration: 129239815, states[0] = -56.169031, states[40]= 0.000285
Saving checkpoint... 
Iteration: 139164642, states[0] = -94.318395, states[40]= 0.000001
Saving checkpoint... 
Iteration: 149358419, states[0] = -94.330256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 159438087, states[0] = -94.209757, states[40]= 0.000001
Saving checkpoint... 
Iteration: 169727594, states[0] = -47.540968, states[40]= 0.000967


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_3000-conf_556.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_3000-conf_556_0_r29565618_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_MID_3000-conf_556_0_r29565618_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.083251
     * GNaL_b in INaL: 0.006151
     * Gto_b in Ito: 0.082028
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032207
     * GKs_b in IKs: 0.001973
     * GK1_b in IK1: 0.163798
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 71.327838
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033446
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 169727594
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -47.540968 (After loading)
 - states[40]: 0.000967 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 177473085, states[0] = -94.248266, states[40]= 0.000001
Saving checkpoint... 
Iteration: 189229938, states[0] = -49.508033, states[40]= 0.000742
Saving checkpoint... 
Iteration: 201447579, states[0] = -94.222589, states[40]= 0.000001
Saving checkpoint... 
Iteration: 209455317, states[0] = -94.329072, states[40]= 0.000001
Saving checkpoint... 
Iteration: 221565254, states[0] = -94.324784, states[40]= 0.000001
Saving checkpoint... 
Iteration: 233040877, states[0] = -94.293086, states[40]= 0.000001
Saving checkpoint... 
Iteration: 244820607, states[0] = -93.918105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255850097, states[0] = -94.331596, states[40]= 0.000001
Saving checkpoint... 
Iteration: 267689086, states[0] = -94.327523, states[40]= 0.000001
Saving checkpoint... 
Iteration: 278972244, states[0] = -94.309338, states[40]= 0.000001
Saving checkpoint... 
Iteration: 291065313, states[0] = 27.414263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302407459, states[0] = -94.329551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 314701390, states[0] = -94.318071, states[40]= 0.000001
Saving checkpoint... 
Iteration: 326268898, states[0] = -94.330552, states[40]= 0.000001
Saving checkpoint... 
Iteration: 338948098, states[0] = -94.309055, states[40]= 0.000001
Saving checkpoint... 
Iteration: 349926312, states[0] = -94.193408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 361513315, states[0] = 31.296365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372613162, states[0] = -94.314573, states[40]= 0.000001
Saving checkpoint... 
Iteration: 383217188, states[0] = -94.327621, states[40]= 0.000001
Saving checkpoint... 
Iteration: 394202020, states[0] = -94.316640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 406301333, states[0] = -94.312710, states[40]= 0.000001
Saving checkpoint... 
Iteration: 417867386, states[0] = -94.328525, states[40]= 0.000001
Saving checkpoint... 
Iteration: 428719052, states[0] = -94.315358, states[40]= 0.000001
Saving checkpoint... 
Iteration: 440053591, states[0] = -94.295204, states[40]= 0.000001
Saving checkpoint... 
Iteration: 451634091, states[0] = 1.237482, states[40]= 0.000349
Saving checkpoint... 
Iteration: 462523197, states[0] = -94.280390, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470411311, states[0] = -94.326445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 474312847, states[0] = -93.878987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486658060, states[0] = -94.320290, states[40]= 0.000001
Saving checkpoint... 
Iteration: 494533566, states[0] = -94.321591, states[40]= 0.000001
Saving checkpoint... 
Iteration: 505844658, states[0] = -94.006276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522417344, states[0] = -94.176825, states[40]= 0.000001
Saving checkpoint... 
Iteration: 536339476, states[0] = -94.326870, states[40]= 0.000001
Saving checkpoint... 
Iteration: 544365299, states[0] = -94.308003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 556011435, states[0] = -94.321359, states[40]= 0.000001
Saving checkpoint... 
Iteration: 566595294, states[0] = -94.317796, states[40]= 0.000001
Saving checkpoint... 
Iteration: 577894133, states[0] = -94.134638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588364581, states[0] = -94.065292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599572500, states[0] = -94.318126, states[40]= 0.000001
Saving checkpoint... 
Iteration: 610765150, states[0] = -89.694916, states[40]= 0.000002
Saving checkpoint... 
Iteration: 621687415, states[0] = -94.321104, states[40]= 0.000001
Saving checkpoint... 
Iteration: 632321876, states[0] = -94.325308, states[40]= 0.000001
Saving checkpoint... 
Iteration: 642349796, states[0] = -94.020624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652751137, states[0] = -68.478525, states[40]= 0.000044
Saving checkpoint... 
Iteration: 662233119, states[0] = -94.323396, states[40]= 0.000001
Saving checkpoint... 
Iteration: 673118739, states[0] = -94.314913, states[40]= 0.000001
Saving checkpoint... 
Iteration: 683741967, states[0] = -94.309873, states[40]= 0.000001
Saving checkpoint... 
Iteration: 693974764, states[0] = -94.320258, states[40]= 0.000001
Saving checkpoint... 
Iteration: 704226832, states[0] = -94.322339, states[40]= 0.000001
Saving checkpoint... 
Iteration: 714256260, states[0] = -75.379341, states[40]= 0.000016
Saving checkpoint... 
Iteration: 724681022, states[0] = -22.657989, states[40]= 0.004619
Saving checkpoint... 
Iteration: 735432253, states[0] = -94.194652, states[40]= 0.000001
Saving checkpoint... 
Iteration: 745979197, states[0] = -94.245034, states[40]= 0.000001
Saving checkpoint... 
Iteration: 756613629, states[0] = -94.307725, states[40]= 0.000001
Saving checkpoint... 
Iteration: 768056687, states[0] = 30.006532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778793732, states[0] = -93.773718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789453994, states[0] = -94.220031, states[40]= 0.000001
Saving checkpoint... 
Iteration: 800353304, states[0] = -94.321876, states[40]= 0.000001
Saving checkpoint... 
Iteration: 810621773, states[0] = -94.308454, states[40]= 0.000001
Saving checkpoint... 
Iteration: 820836965, states[0] = -93.973360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830637290, states[0] = -94.311309, states[40]= 0.000001
Saving checkpoint... 
Iteration: 841042836, states[0] = -94.314946, states[40]= 0.000001
Saving checkpoint... 
Iteration: 852116741, states[0] = 8.272901, states[40]= 0.000095
Saving checkpoint... 
Iteration: 862986701, states[0] = -94.249023, states[40]= 0.000001
Saving checkpoint... 
Iteration: 873285966, states[0] = -93.723872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883273295, states[0] = -94.305088, states[40]= 0.000001
Saving checkpoint... 
Iteration: 893178289, states[0] = -94.315300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 902866044, states[0] = -94.301478, states[40]= 0.000001
Saving checkpoint... 
Iteration: 913399557, states[0] = -94.300185, states[40]= 0.000001
Saving checkpoint... 
Iteration: 924365228, states[0] = -94.060843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934188652, states[0] = -94.307386, states[40]= 0.000001
Saving checkpoint... 
Iteration: 944089973, states[0] = -94.298441, states[40]= 0.000001
Saving checkpoint... 
Iteration: 954147967, states[0] = -5.322254, states[40]= 0.000687
Saving checkpoint... 
Iteration: 960849102, states[0] = -94.319046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 971502733, states[0] = -94.314177, states[40]= 0.000001
Saving checkpoint... 
Iteration: 982414929, states[0] = -94.298450, states[40]= 0.000001
Saving checkpoint... 
Iteration: 992852185, states[0] = -94.300320, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1004017978, states[0] = -94.267628, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1013985324, states[0] = -94.295737, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1024539877, states[0] = 33.499724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035797157, states[0] = -94.318053, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1046750346, states[0] = -94.302987, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1057622486, states[0] = 6.004294, states[40]= 0.000151
Saving checkpoint... 
Iteration: 1068471026, states[0] = -94.231970, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1079550138, states[0] = -94.310339, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1089721120, states[0] = -94.315065, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1099038953, states[0] = -94.310436, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1110038472, states[0] = 33.664048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120377270, states[0] = -94.297166, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1131377944, states[0] = -94.089265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142364206, states[0] = -94.315485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1152819792, states[0] = -94.315901, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1163597268, states[0] = -94.306903, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1174373114, states[0] = -94.296327, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1185104428, states[0] = 13.080859, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1195152467, states[0] = -94.304100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1205442319, states[0] = -94.312153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1217095547, states[0] = -94.295018, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1228385330, states[0] = -94.294943, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1239730611, states[0] = -94.312828, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1251243381, states[0] = -60.634745, states[40]= 0.000144
Saving checkpoint... 
Iteration: 1263010610, states[0] = 29.900858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274485842, states[0] = -94.309334, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1285292043, states[0] = -94.297125, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1296553575, states[0] = -94.279664, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1307187059, states[0] = -94.308659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1318253127, states[0] = -94.297959, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1329790426, states[0] = -94.312693, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1341342222, states[0] = -93.982465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352457508, states[0] = -94.308963, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1363509194, states[0] = 28.933751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374516879, states[0] = -94.260251, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1384985511, states[0] = -94.238587, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1396382843, states[0] = -94.291981, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1408437348, states[0] = -94.290029, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1419513907, states[0] = -94.257682, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1430991002, states[0] = -94.288016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1442058269, states[0] = -94.278896, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1453579281, states[0] = 22.606631, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1465149039, states[0] = -94.299353, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1475724751, states[0] = -94.296186, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1487423339, states[0] = -94.307677, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1498361236, states[0] = -94.290858, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.162465
 - CaMKt in component CaMK (millimolar): 0.004442
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 7.903992
 - nass in component intracellular_ions (millimolar): 7.904156
 - ki in component intracellular_ions (millimolar): 143.813461
 - kss in component intracellular_ions (millimolar): 143.813442
 - cansr in component intracellular_ions (millimolar): 1.925044
 - cajsr in component intracellular_ions (millimolar): 1.927300
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.003899
 - hf in component INa (dimensionless): 0.866566
 - hs in component INa (dimensionless): 0.866568
 - j in component INa (dimensionless): 0.866574
 - hsp in component INa (dimensionless): 0.701036
 - jp in component INa (dimensionless): 0.866578
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709311
 - hLp in component INaL (dimensionless): 0.511153
 - a in component Ito (dimensionless): 0.000655
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.964272
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.981389
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.985673
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004843
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.033815
 - xs1 in component IKs (dimensionless): 0.093508
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997525
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
04:09:51 (62564): called boinc_finish(0)

</stderr_txt>
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