𝕏

Task 55867466

Name HuVeMOp_20240703071643700359_ORdGradInc_k_26-Schmidt_3000-conf_654_1
Workunit 26530370
Created 3 Jul 2024, 5:20:17 UTC
Sent 3 Jul 2024, 9:22:11 UTC
Report deadline 6 Jul 2024, 9:22:11 UTC
Received 3 Jul 2024, 17:44:30 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 51 min 2 sec
CPU time 1 hours 44 min 24 sec
Validate state Valid
Credit 45.02
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.20 MB
Peak swap size 4.13 GB
Peak disk usage 0.95 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Schmidt_3000-conf_654.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Schmidt_3000-conf_654_1_r1327977730_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Schmidt_3000-conf_654_1_r1327977730_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.178000
     * GNaL_b in INaL: 0.005914
     * Gto_b in Ito: 0.086792
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032254
     * GKs_b in IKs: 0.001966
     * GK1_b in IK1: 0.165533
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.025969
     * GKb_b in IKb: 0.003835
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036397
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1498500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9690372, states[0] = -84.342616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 19673376, states[0] = -71.019687, states[40]= 0.000002
Saving checkpoint... 
Iteration: 29343724, states[0] = -84.185436, states[40]= 0.000001
Saving checkpoint... 
Iteration: 39382445, states[0] = -84.012836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 49898746, states[0] = -84.011350, states[40]= 0.000001
Saving checkpoint... 
Iteration: 61030458, states[0] = -84.106418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 72915725, states[0] = -84.099566, states[40]= 0.000001
Saving checkpoint... 
Iteration: 83847118, states[0] = -84.071814, states[40]= 0.000001
Saving checkpoint... 
Iteration: 94425505, states[0] = -84.062961, states[40]= 0.000001
Saving checkpoint... 
Iteration: 106105554, states[0] = -84.072114, states[40]= 0.000001
Saving checkpoint... 
Iteration: 117768609, states[0] = -84.081776, states[40]= 0.000001
Saving checkpoint... 
Iteration: 129926972, states[0] = -84.074586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 141198354, states[0] = -82.382740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153320813, states[0] = -83.811183, states[40]= 0.000001
Saving checkpoint... 
Iteration: 165203688, states[0] = -83.019676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176541564, states[0] = -84.064091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 188573593, states[0] = -84.061905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 199864366, states[0] = -83.902277, states[40]= 0.000001
Saving checkpoint... 
Iteration: 211150377, states[0] = -84.057387, states[40]= 0.000001
Saving checkpoint... 
Iteration: 222606211, states[0] = -84.063015, states[40]= 0.000001
Saving checkpoint... 
Iteration: 233552970, states[0] = -84.061719, states[40]= 0.000001
Saving checkpoint... 
Iteration: 244214907, states[0] = -84.053732, states[40]= 0.000001
Saving checkpoint... 
Iteration: 254758569, states[0] = -84.051631, states[40]= 0.000001
Saving checkpoint... 
Iteration: 265558922, states[0] = 19.479407, states[40]= 0.000117
Saving checkpoint... 
Iteration: 276917936, states[0] = -84.067674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 287653165, states[0] = -84.056241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 298525558, states[0] = 29.970641, states[40]= 0.000249
Saving checkpoint... 
Iteration: 309245191, states[0] = -83.509974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319117179, states[0] = -84.057809, states[40]= 0.000001
Saving checkpoint... 
Iteration: 329870074, states[0] = -84.046422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 341250924, states[0] = -84.071549, states[40]= 0.000001
Saving checkpoint... 
Iteration: 352624033, states[0] = -16.266439, states[40]= 0.000635
Saving checkpoint... 
Iteration: 363426946, states[0] = -83.981433, states[40]= 0.000001
Saving checkpoint... 
Iteration: 373934915, states[0] = -83.988622, states[40]= 0.000001
Saving checkpoint... 
Iteration: 384367886, states[0] = -83.906440, states[40]= 0.000001
Saving checkpoint... 
Iteration: 395470342, states[0] = -84.064702, states[40]= 0.000001
Saving checkpoint... 
Iteration: 406382592, states[0] = -84.045611, states[40]= 0.000001
Saving checkpoint... 
Iteration: 416843655, states[0] = -84.047131, states[40]= 0.000001
Saving checkpoint... 
Iteration: 427376259, states[0] = -84.045781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 438648901, states[0] = -84.066857, states[40]= 0.000001
Saving checkpoint... 
Iteration: 449414563, states[0] = -84.067034, states[40]= 0.000001
Saving checkpoint... 
Iteration: 460207113, states[0] = -84.052937, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470991078, states[0] = -84.041356, states[40]= 0.000001
Saving checkpoint... 
Iteration: 481403976, states[0] = -84.044500, states[40]= 0.000001
Saving checkpoint... 
Iteration: 492385888, states[0] = -83.933538, states[40]= 0.000001
Saving checkpoint... 
Iteration: 503426893, states[0] = -84.066297, states[40]= 0.000001
Saving checkpoint... 
Iteration: 513812747, states[0] = -84.070269, states[40]= 0.000001
Saving checkpoint... 
Iteration: 525012711, states[0] = 30.416633, states[40]= 0.021053
Saving checkpoint... 
Iteration: 534981108, states[0] = -84.063667, states[40]= 0.000001
Saving checkpoint... 
Iteration: 545728288, states[0] = -84.051646, states[40]= 0.000001
Saving checkpoint... 
Iteration: 556911317, states[0] = -83.964818, states[40]= 0.000001
Saving checkpoint... 
Iteration: 567718654, states[0] = -84.070234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 578760841, states[0] = -84.050060, states[40]= 0.000001
Saving checkpoint... 
Iteration: 589230663, states[0] = -84.051378, states[40]= 0.000001
Saving checkpoint... 
Iteration: 600083985, states[0] = 9.266411, states[40]= 0.000479
Saving checkpoint... 
Iteration: 610226594, states[0] = -84.051486, states[40]= 0.000001
Saving checkpoint... 
Iteration: 620516772, states[0] = -84.061614, states[40]= 0.000001
Saving checkpoint... 
Iteration: 630582071, states[0] = -84.056532, states[40]= 0.000001
Saving checkpoint... 
Iteration: 639905876, states[0] = -84.066698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 650938417, states[0] = -84.042577, states[40]= 0.000001
Saving checkpoint... 
Iteration: 661832150, states[0] = -83.833957, states[40]= 0.000001
Saving checkpoint... 
Iteration: 672564455, states[0] = -84.052387, states[40]= 0.000001
Saving checkpoint... 
Iteration: 683723797, states[0] = -84.051343, states[40]= 0.000001
Saving checkpoint... 
Iteration: 693874576, states[0] = -84.067737, states[40]= 0.000001
Saving checkpoint... 
Iteration: 703631668, states[0] = -23.166899, states[40]= 0.000608
Saving checkpoint... 
Iteration: 714266597, states[0] = -83.614146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724345121, states[0] = -84.045932, states[40]= 0.000001
Saving checkpoint... 
Iteration: 734713998, states[0] = -84.051605, states[40]= 0.000001
Saving checkpoint... 
Iteration: 745107879, states[0] = -84.056644, states[40]= 0.000001
Saving checkpoint... 
Iteration: 756004721, states[0] = 29.024876, states[40]= 0.343595
Saving checkpoint... 
Iteration: 766336833, states[0] = -84.046117, states[40]= 0.000001
Saving checkpoint... 
Iteration: 776091030, states[0] = -84.057754, states[40]= 0.000001
Saving checkpoint... 
Iteration: 787160056, states[0] = -84.053951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 797725748, states[0] = -84.050833, states[40]= 0.000001
Saving checkpoint... 
Iteration: 809118237, states[0] = -84.062009, states[40]= 0.000001
Saving checkpoint... 
Iteration: 819814945, states[0] = -84.069094, states[40]= 0.000001
Saving checkpoint... 
Iteration: 830991417, states[0] = -84.040014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 842403055, states[0] = -84.066070, states[40]= 0.000001
Saving checkpoint... 
Iteration: 854214004, states[0] = -84.069058, states[40]= 0.000001
Saving checkpoint... 
Iteration: 865754249, states[0] = -83.554714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878308459, states[0] = -84.069019, states[40]= 0.000001
Saving checkpoint... 
Iteration: 889968255, states[0] = -84.011666, states[40]= 0.000001
Saving checkpoint... 
Iteration: 901556933, states[0] = 20.238506, states[40]= 0.000104
Saving checkpoint... 
Iteration: 913365924, states[0] = -84.044394, states[40]= 0.000001
Saving checkpoint... 
Iteration: 925869813, states[0] = -83.907596, states[40]= 0.000001
Saving checkpoint... 
Iteration: 938622270, states[0] = -84.055224, states[40]= 0.000001
Saving checkpoint... 
Iteration: 951216430, states[0] = -83.332759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964271831, states[0] = -84.048153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 976588726, states[0] = 7.166482, states[40]= 0.000604
Saving checkpoint... 
Iteration: 989166206, states[0] = -84.066244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1000991407, states[0] = -84.024485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1013118275, states[0] = -84.061263, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1024595492, states[0] = 3.993559, states[40]= 0.000811
Saving checkpoint... 
Iteration: 1036527207, states[0] = 29.648998, states[40]= 0.000148
Saving checkpoint... 
Iteration: 1049821796, states[0] = -84.045695, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1062575873, states[0] = -84.053621, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1075106155, states[0] = -84.055512, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1087931824, states[0] = -83.983227, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1100074483, states[0] = -84.053175, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1112255040, states[0] = -84.068697, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1124815685, states[0] = -84.045675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1137928847, states[0] = -84.063873, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1150421128, states[0] = -84.041377, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1162326860, states[0] = -84.045068, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1174890157, states[0] = -83.936848, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1187121175, states[0] = -84.061012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1199874674, states[0] = -84.042988, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1211803932, states[0] = -84.045851, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1222560592, states[0] = 18.841626, states[40]= 0.000130
Saving checkpoint... 
Iteration: 1234152794, states[0] = -84.052652, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1246152439, states[0] = -84.052625, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1256994804, states[0] = -84.038323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1268256497, states[0] = -84.068126, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1279755682, states[0] = -83.560272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290244059, states[0] = -83.500062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300584096, states[0] = 9.219332, states[40]= 0.000482
Saving checkpoint... 
Iteration: 1310504663, states[0] = -84.059666, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1321280761, states[0] = -84.046445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1332026462, states[0] = 29.800005, states[40]= 0.000187
Saving checkpoint... 
Iteration: 1341973913, states[0] = -84.061039, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1353389555, states[0] = -83.935375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1369778664, states[0] = -83.663272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381178233, states[0] = -84.050894, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1391248066, states[0] = -84.067643, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1401836746, states[0] = -84.066388, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1413105623, states[0] = -1.499899, states[40]= 0.001098
Saving checkpoint... 
Iteration: 1423944721, states[0] = -83.992905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1435231984, states[0] = -84.048196, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1445662899, states[0] = -84.051387, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1455642304, states[0] = -84.062475, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1466289718, states[0] = -84.067179, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1477700778, states[0] = -82.713201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488202998, states[0] = -82.946009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498699234, states[0] = -82.471912, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -83.913204
 - CaMKt in component CaMK (millimolar): 0.002711
 - cass in component intracellular_ions (millimolar): 0.000090
 - nai in component intracellular_ions (millimolar): 6.206025
 - nass in component intracellular_ions (millimolar): 6.206132
 - ki in component intracellular_ions (millimolar): 145.677037
 - kss in component intracellular_ions (millimolar): 145.677023
 - cansr in component intracellular_ions (millimolar): 1.667739
 - cajsr in component intracellular_ions (millimolar): 1.667910
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.010935
 - hf in component INa (dimensionless): 0.546580
 - hs in component INa (dimensionless): 0.546584
 - j in component INa (dimensionless): 0.546600
 - hsp in component INa (dimensionless): 0.303260
 - jp in component INa (dimensionless): 0.546610
 - mL in component INaL (dimensionless): 0.000400
 - hL in component INaL (dimensionless): 0.383050
 - hLp in component INaL (dimensionless): 0.212158
 - a in component Ito (dimensionless): 0.001308
 - iF in component Ito (dimensionless): 0.999108
 - iS in component Ito (dimensionless): 0.948324
 - ap in component Ito (dimensionless): 0.000666
 - iFp in component Ito (dimensionless): 0.999108
 - iSp in component Ito (dimensionless): 0.962543
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.990844
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003434
 - xrf in component IKr (dimensionless): 0.000014
 - xrs in component IKr (dimensionless): 0.086016
 - xs1 in component IKs (dimensionless): 0.071894
 - xs2 in component IKs (dimensionless): 0.000300
 - xk1 in component IK1 (dimensionless): 0.996939
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
12:45:52 (30898): called boinc_finish(0)

</stderr_txt>
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