𝕏

Task 55867327

Name HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_ENDO_6000-conf_853_0
Workunit 26530301
Created 3 Jul 2024, 5:20:12 UTC
Sent 3 Jul 2024, 9:21:21 UTC
Report deadline 6 Jul 2024, 9:21:21 UTC
Received 5 Jul 2024, 7:28:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 52 min 19 sec
CPU time 1 hours 40 min 45 sec
Validate state Valid
Credit 45.15
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.99 MB
Peak swap size 32.91 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_ENDO_6000-conf_853.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_ENDO_6000-conf_853_0_r873031560_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Drouin_ENDO_6000-conf_853_0_r873031560_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.725132
     * GNaL_b in INaL: 0.005464
     * Gto_b in Ito: 0.081078
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032373
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.164609
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.361937
     * GKb_b in IKb: 0.003768
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036807
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9976392, states[0] = -94.145028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20742997, states[0] = -94.035191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30164303, states[0] = -45.279116, states[40]= 0.000381
Saving checkpoint... 
Iteration: 40643125, states[0] = -93.985587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50261301, states[0] = -93.966766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60871511, states[0] = -93.992855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70434308, states[0] = -93.971951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81279149, states[0] = -93.607106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91815058, states[0] = -93.960681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101675167, states[0] = -93.950418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111692263, states[0] = -93.985139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122252540, states[0] = -93.953048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131930040, states[0] = -93.947545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142070514, states[0] = -93.978136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151184292, states[0] = -93.973941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160717053, states[0] = -93.959838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171703868, states[0] = -93.984295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182187409, states[0] = -93.952700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192048480, states[0] = 25.312857, states[40]= 0.000381
Saving checkpoint... 
Iteration: 202333705, states[0] = -93.968677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212550082, states[0] = -93.949107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222493903, states[0] = -93.942791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232437511, states[0] = -93.965651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242855115, states[0] = -93.946929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252466062, states[0] = -93.927551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262337169, states[0] = -93.968375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271488016, states[0] = -93.964259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281537790, states[0] = -93.949011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291743838, states[0] = -93.984915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302435569, states[0] = -93.949823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311921166, states[0] = -93.946406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321470156, states[0] = -93.929901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331228662, states[0] = -93.971640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341276417, states[0] = -93.951267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350843281, states[0] = -93.946789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360498615, states[0] = -93.944695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370651005, states[0] = -93.960403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380838181, states[0] = -93.946772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391289979, states[0] = -93.969580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402178655, states[0] = -54.532289, states[40]= 0.000115
Saving checkpoint... 
Iteration: 412527484, states[0] = -93.963063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423000038, states[0] = -89.252840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432764963, states[0] = -93.984904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442995074, states[0] = -93.954470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452931017, states[0] = -93.946128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462315484, states[0] = -93.718144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472515914, states[0] = -93.963247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482924452, states[0] = -93.946118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491929592, states[0] = -93.946075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502084185, states[0] = -93.976402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511883509, states[0] = -93.956008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522083785, states[0] = 12.082523, states[40]= 0.002188
Saving checkpoint... 
Iteration: 531691075, states[0] = -93.982853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542017973, states[0] = -93.954004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551524436, states[0] = -93.948686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561219976, states[0] = -92.703158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571603404, states[0] = -93.961096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581648976, states[0] = -93.947698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592106411, states[0] = -93.975463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602308151, states[0] = -93.950541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611536312, states[0] = -93.948499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621498530, states[0] = -93.944254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631196073, states[0] = -93.972265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641203011, states[0] = -93.951586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651481222, states[0] = -93.935646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660986426, states[0] = -93.979674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670305477, states[0] = -93.968674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680288958, states[0] = -93.950614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690676455, states[0] = -93.981772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701021606, states[0] = -93.953711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711331833, states[0] = -93.757905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722016731, states[0] = -93.953744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731824711, states[0] = -93.946312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741196935, states[0] = -70.630131, states[40]= 0.000008
Saving checkpoint... 
Iteration: 751330476, states[0] = -93.967795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761291407, states[0] = -93.950465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770785807, states[0] = -93.946492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780079430, states[0] = 13.905699, states[40]= 0.001837
Saving checkpoint... 
Iteration: 789782835, states[0] = -93.984384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798925057, states[0] = -93.981519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808023208, states[0] = -93.978138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818033113, states[0] = -93.953377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827753347, states[0] = -93.946611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837454489, states[0] = -93.919047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847111358, states[0] = -93.974894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857231010, states[0] = -93.950948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866784615, states[0] = -93.946352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876696962, states[0] = -93.982609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886671317, states[0] = -93.959197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896101560, states[0] = -93.952380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906681894, states[0] = -93.981775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915963753, states[0] = -93.980068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926378526, states[0] = -93.949367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936324636, states[0] = -93.740689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946138530, states[0] = -93.973776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952073306, states[0] = -93.976105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961957637, states[0] = -93.954201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971722874, states[0] = -93.946589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982039132, states[0] = -93.977297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991587375, states[0] = -93.960801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002179226, states[0] = -54.989178, states[40]= 0.000107
Saving checkpoint... 
Iteration: 1012526715, states[0] = -93.962159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022089630, states[0] = -93.952335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032203575, states[0] = -78.555016, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1042765505, states[0] = -93.957171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052481888, states[0] = -93.948264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062480776, states[0] = -93.934775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072622617, states[0] = -93.959914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083262319, states[0] = -93.531914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093550978, states[0] = -93.961467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103881218, states[0] = -93.945406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113832274, states[0] = -93.983389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120960342, states[0] = -93.953917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128353916, states[0] = -93.802055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136013262, states[0] = -93.953155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146181452, states[0] = -56.783223, states[40]= 0.000080
Saving checkpoint... 
Iteration: 1153418895, states[0] = -93.964672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161047829, states[0] = 25.527052, states[40]= 0.000368
Saving checkpoint... 
Iteration: 1172374401, states[0] = -93.949027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183700342, states[0] = -93.958169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191558936, states[0] = -93.964215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203534652, states[0] = -93.957255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215440112, states[0] = -93.907833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226892553, states[0] = -93.945152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238785138, states[0] = -93.945776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250364663, states[0] = -93.948998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261630450, states[0] = -93.959458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272751105, states[0] = -93.983499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283993267, states[0] = -93.944515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295850487, states[0] = -93.945290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307611645, states[0] = -93.946852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318943731, states[0] = -93.953854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330254723, states[0] = -93.969253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341360762, states[0] = -93.813736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352093199, states[0] = -93.951783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363684949, states[0] = -93.958193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375239897, states[0] = -93.969664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386894633, states[0] = -93.981526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397986415, states[0] = -93.944375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408906022, states[0] = -93.954280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420414926, states[0] = -93.964369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431943356, states[0] = -93.979959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443742427, states[0] = -93.983115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451187035, states[0] = -93.950518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455098418, states[0] = 5.319885, states[40]= 0.003428
Saving checkpoint... 
Iteration: 1467078522, states[0] = 14.278078, states[40]= 0.001768
Saving checkpoint... 
Iteration: 1475189627, states[0] = -93.950452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486286024, states[0] = -93.968021, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.820127
 - CaMKt in component CaMK (millimolar): 0.001297
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.640263
 - nass in component intracellular_ions (millimolar): 6.640386
 - ki in component intracellular_ions (millimolar): 145.226852
 - kss in component intracellular_ions (millimolar): 145.226843
 - cansr in component intracellular_ions (millimolar): 1.821646
 - cajsr in component intracellular_ions (millimolar): 1.821516
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.004036
 - hf in component INa (dimensionless): 0.859927
 - hs in component INa (dimensionless): 0.859927
 - j in component INa (dimensionless): 0.859928
 - hsp in component INa (dimensionless): 0.689109
 - jp in component INa (dimensionless): 0.859929
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.699724
 - hLp in component INaL (dimensionless): 0.504527
 - a in component Ito (dimensionless): 0.000671
 - iF in component Ito (dimensionless): 0.999842
 - iS in component Ito (dimensionless): 0.999234
 - ap in component Ito (dimensionless): 0.000342
 - iFp in component Ito (dimensionless): 0.999842
 - iSp in component Ito (dimensionless): 0.999702
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999526
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005354
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000576
 - xs1 in component IKs (dimensionless): 0.014595
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997607
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:34:50 (60991): called boinc_finish(0)

</stderr_txt>
]]>


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