𝕏

Task 55865693

Name HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_443_1
Workunit 26529484
Created 3 Jul 2024, 5:19:30 UTC
Sent 3 Jul 2024, 9:09:21 UTC
Report deadline 6 Jul 2024, 18:45:21 UTC
Received 4 Jul 2024, 20:05:11 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240892
Run time 3 hours 8 min 8 sec
CPU time 1 hours 35 min 7 sec
Validate state Valid
Credit 65.37
Device peak FLOPS 5.74 GFLOPS
Application version Human ventricular cell models optimization v0.02
aarch64-unknown-linux-gnu
Peak working set size 2.00 MB
Peak swap size 11.17 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_443.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_443_1_r1592662452_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_443_1_r1592662452_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.664101
     * GNaL_b in INaL: 0.005944
     * Gto_b in Ito: 0.085874
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031708
     * GKs_b in IKs: 0.001897
     * GK1_b in IK1: 0.163771
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 71.379139
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035493
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11613330, states[0] = -36.445801, states[40]= 0.000199
Saving checkpoint... 
Iteration: 23399233, states[0] = -95.069849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35130532, states[0] = -51.482049, states[40]= 0.000022
Saving checkpoint... 
Iteration: 46205533, states[0] = -94.868510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57940889, states[0] = -95.039527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69415896, states[0] = -95.028049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80602409, states[0] = -21.731720, states[40]= 0.000864
Saving checkpoint... 
Iteration: 91903544, states[0] = -95.017855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103043209, states[0] = 14.197722, states[40]= 0.005113
Saving checkpoint... 
Iteration: 114752148, states[0] = -94.916745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127142096, states[0] = -61.630323, states[40]= 0.000004
Saving checkpoint... 
Iteration: 139177512, states[0] = -94.745501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150555849, states[0] = 9.403879, states[40]= 0.004886
Saving checkpoint... 
Iteration: 162089569, states[0] = -9.441955, states[40]= 0.002439
Saving checkpoint... 
Iteration: 174653655, states[0] = -77.485528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185824931, states[0] = -94.977967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197073664, states[0] = 1.326834, states[40]= 0.004392
Saving checkpoint... 
Iteration: 209517989, states[0] = 21.571192, states[40]= 0.012013
Saving checkpoint... 
Iteration: 221301512, states[0] = -94.961807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233096331, states[0] = -15.464294, states[40]= 0.001399
Saving checkpoint... 
Iteration: 244033962, states[0] = 17.487827, states[40]= 0.005628
Saving checkpoint... 
Iteration: 254773142, states[0] = -94.936749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266267641, states[0] = -94.930996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277742071, states[0] = -94.899666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289442270, states[0] = -95.019847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301238979, states[0] = -94.895269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312508317, states[0] = 23.813634, states[40]= 0.078814
Saving checkpoint... 
Iteration: 323343175, states[0] = -94.987494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334731167, states[0] = -94.883586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346629894, states[0] = -47.905999, states[40]= 0.000039
Saving checkpoint... 
Iteration: 357775776, states[0] = -94.939259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368731942, states[0] = -94.884757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379976253, states[0] = -95.025527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391342848, states[0] = -94.987279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402245432, states[0] = -94.904155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413348452, states[0] = -94.990020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424439560, states[0] = -95.019198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435714628, states[0] = -94.855805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446689292, states[0] = -94.805009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458955078, states[0] = -95.022107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470725550, states[0] = -94.874552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482893588, states[0] = -95.007518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493966005, states[0] = -95.023907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505072086, states[0] = 2.158576, states[40]= 0.004478
Saving checkpoint... 
Iteration: 516125510, states[0] = -43.336505, states[40]= 0.000079
Saving checkpoint... 
Iteration: 528368395, states[0] = -94.998629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539488300, states[0] = -95.027061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550466050, states[0] = -95.023878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561303492, states[0] = -94.962925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571791459, states[0] = -94.953401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583542177, states[0] = 14.652232, states[40]= 0.005147
Saving checkpoint... 
Iteration: 594953219, states[0] = -95.021692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606006149, states[0] = 25.974750, states[40]= 0.124866
Saving checkpoint... 
Iteration: 617123522, states[0] = -41.322317, states[40]= 0.000107
Saving checkpoint... 
Iteration: 628848350, states[0] = -94.989834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640002649, states[0] = 39.719437, states[40]= 0.119319
Saving checkpoint... 
Iteration: 651311616, states[0] = -94.968673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661879281, states[0] = -95.002633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672698931, states[0] = -94.825583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683770344, states[0] = -94.933545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696224913, states[0] = -94.873364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707652174, states[0] = -74.986390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718211218, states[0] = -94.849393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729769026, states[0] = -94.932134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741031146, states[0] = 18.374027, states[40]= 0.005922
Saving checkpoint... 
Iteration: 751890897, states[0] = -95.006498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763004615, states[0] = 29.475618, states[40]= 0.152098
Saving checkpoint... 
Iteration: 773801792, states[0] = -94.961514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785313217, states[0] = -94.969678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796255735, states[0] = -94.917054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806775646, states[0] = -94.938843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817504343, states[0] = 30.408977, states[40]= 0.153699
Saving checkpoint... 
Iteration: 828104533, states[0] = -23.151986, states[40]= 0.000793
Saving checkpoint... 
Iteration: 838923144, states[0] = -95.015338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850199053, states[0] = -94.825717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861538739, states[0] = 15.877868, states[40]= 0.005297
Saving checkpoint... 
Iteration: 873253825, states[0] = -94.914670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883342243, states[0] = -94.986661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894240072, states[0] = -94.896437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907115518, states[0] = -33.517801, states[40]= 0.000315
Saving checkpoint... 
Iteration: 919765937, states[0] = -94.928699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932604250, states[0] = -22.886297, states[40]= 0.000806
Saving checkpoint... 
Iteration: 944052716, states[0] = 10.672382, states[40]= 0.004924
Saving checkpoint... 
Iteration: 955198309, states[0] = -94.824139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966133199, states[0] = -51.449690, states[40]= 0.000022
Saving checkpoint... 
Iteration: 977893021, states[0] = -95.007028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990489718, states[0] = -95.026957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001913718, states[0] = -95.012906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011893066, states[0] = -95.007020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023356635, states[0] = -94.993398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035119172, states[0] = -37.031656, states[40]= 0.000198
Saving checkpoint... 
Iteration: 1046464454, states[0] = -95.023310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058067946, states[0] = 4.191640, states[40]= 0.004647
Saving checkpoint... 
Iteration: 1070439644, states[0] = -95.018807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082761651, states[0] = -94.923819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095375136, states[0] = -95.000852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107527031, states[0] = 19.557312, states[40]= 0.006591
Saving checkpoint... 
Iteration: 1119017662, states[0] = 21.630025, states[40]= 0.012509
Saving checkpoint... 
Iteration: 1130755419, states[0] = -94.916458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142444070, states[0] = -95.019640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153021959, states[0] = 20.795787, states[40]= 0.008362
Saving checkpoint... 
Iteration: 1164640729, states[0] = -59.825510, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1175594077, states[0] = -13.378287, states[40]= 0.001702
Saving checkpoint... 
Iteration: 1187080906, states[0] = -2.910171, states[40]= 0.003780
Saving checkpoint... 
Iteration: 1197388432, states[0] = -95.005420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208992728, states[0] = -95.027194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220982220, states[0] = -95.025828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232340472, states[0] = -94.985533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244318033, states[0] = -94.972562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255196452, states[0] = -94.820137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266163815, states[0] = -92.127312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276735417, states[0] = -94.889432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288280432, states[0] = -94.943147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299766896, states[0] = -94.929498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311177324, states[0] = -94.738552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322899548, states[0] = -95.008793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334464009, states[0] = -95.023057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346071722, states[0] = 2.344512, states[40]= 0.004496
Saving checkpoint... 
Iteration: 1358207016, states[0] = -94.841071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369877475, states[0] = -95.001536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381582230, states[0] = -3.791266, states[40]= 0.003617
Saving checkpoint... 
Iteration: 1392435188, states[0] = -95.017682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405210725, states[0] = -94.848040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418464480, states[0] = -95.023080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430898511, states[0] = -95.008418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443249203, states[0] = -94.908467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455923451, states[0] = -95.015021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465795281, states[0] = -94.955983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477582818, states[0] = -4.194838, states[40]= 0.003540
Saving checkpoint... 
Iteration: 1488780541, states[0] = -94.943122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499736857, states[0] = -94.891415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511333071, states[0] = -95.198663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1522501080, states[0] = 49.256334, states[40]= 0.023526
Saving checkpoint... 
Iteration: 1535569319, states[0] = -95.102465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1547071769, states[0] = -95.270275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1558937433, states[0] = -88.472911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1570372397, states[0] = -95.126494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582373237, states[0] = -95.131138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595796568, states[0] = -33.510458, states[40]= 0.000311
Saving checkpoint... 
Iteration: 1606539370, states[0] = 13.001161, states[40]= 0.006103
Saving checkpoint... 
Iteration: 1617705744, states[0] = -43.862213, states[40]= 0.000075
Saving checkpoint... 
Iteration: 1629420328, states[0] = -61.813050, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1640813030, states[0] = -52.623434, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1652462815, states[0] = -0.094846, states[40]= 0.004767
Saving checkpoint... 
Iteration: 1663877370, states[0] = -12.862784, states[40]= 0.002027
Saving checkpoint... 
Iteration: 1675413030, states[0] = -95.216633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686871087, states[0] = -95.285981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1698292100, states[0] = -95.302066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1709671928, states[0] = -95.286766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1721337884, states[0] = -95.251946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1733207564, states[0] = -46.090082, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1745479677, states[0] = -15.341345, states[40]= 0.001596
Saving checkpoint... 
Iteration: 1757181737, states[0] = -17.573992, states[40]= 0.001293
Saving checkpoint... 
Iteration: 1768962371, states[0] = -95.106328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780025872, states[0] = -69.704713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1791542125, states[0] = -95.257024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803180474, states[0] = -94.827997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814815164, states[0] = -95.013816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825692018, states[0] = -94.842576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837091353, states[0] = -12.152850, states[40]= 0.001924
Saving checkpoint... 
Iteration: 1849551591, states[0] = 10.829743, states[40]= 0.004944
Saving checkpoint... 
Iteration: 1861200556, states[0] = -94.839723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873542884, states[0] = 14.275089, states[40]= 0.005124
Saving checkpoint... 
Iteration: 1885000592, states[0] = 35.410716, states[40]= 0.001779
Saving checkpoint... 
Iteration: 1896710817, states[0] = -94.851917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908748813, states[0] = -94.910445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920948898, states[0] = -95.021945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932369281, states[0] = -94.999417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944558709, states[0] = 8.240212, states[40]= 0.004848
Saving checkpoint... 
Iteration: 1956501967, states[0] = 45.230182, states[40]= 0.085525
Saving checkpoint... 
Iteration: 1968652209, states[0] = -75.096155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980344939, states[0] = -94.987598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1992588271, states[0] = -8.328598, states[40]= 0.002674
Saving checkpoint... 
Iteration: 2005073225, states[0] = 1.563705, states[40]= 0.004418
Saving checkpoint... 
Iteration: 2015984095, states[0] = -95.025640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027228601, states[0] = -94.878509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039192714, states[0] = -94.811740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050785736, states[0] = -94.947501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2061872632, states[0] = -94.999276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072759799, states[0] = -94.921028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083141036, states[0] = -60.180482, states[40]= 0.000005
Saving checkpoint... 
Iteration: 2094224133, states[0] = -94.871144, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.903325
 - CaMKt in component CaMK (millimolar): 0.006970
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.558822
 - nass in component intracellular_ions (millimolar): 6.558881
 - ki in component intracellular_ions (millimolar): 145.419251
 - kss in component intracellular_ions (millimolar): 145.419231
 - cansr in component intracellular_ions (millimolar): 1.309966
 - cajsr in component intracellular_ions (millimolar): 1.271903
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003618
 - hf in component INa (dimensionless): 0.880026
 - hs in component INa (dimensionless): 0.880022
 - j in component INa (dimensionless): 0.879993
 - hsp in component INa (dimensionless): 0.725879
 - jp in component INa (dimensionless): 0.879974
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709786
 - hLp in component INaL (dimensionless): 0.451531
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620466
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695184
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934917
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999884
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001593
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332782
 - xs1 in component IKs (dimensionless): 0.242690
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:04:31 (125177): called boinc_finish(0)

</stderr_txt>
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