𝕏

Task 55863846

Name HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pieske_1000-conf_132_0
Workunit 26528561
Created 3 Jul 2024, 5:18:38 UTC
Sent 3 Jul 2024, 8:58:59 UTC
Report deadline 6 Jul 2024, 8:58:59 UTC
Received 4 Jul 2024, 5:01:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231453
Run time 2 hours 14 min 33 sec
CPU time 1 hours 25 min 34 sec
Validate state Valid
Credit 48.47
Device peak FLOPS 4.52 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.23 MB
Peak swap size 5.31 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pieske_1000-conf_132.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pieske_1000-conf_132_0_r1986973295_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pieske_1000-conf_132_0_r1986973295_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.114106
     * GNaL_b in INaL: 0.005955
     * Gto_b in Ito: 0.086105
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031937
     * GKs_b in IKs: 0.001908
     * GK1_b in IK1: 0.166287
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.212065
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029036
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10068290, states[0] = 1.116353, states[40]= 0.004274
Saving checkpoint... 
Iteration: 18929253, states[0] = -87.066284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27740870, states[0] = -86.911060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36720204, states[0] = -86.855446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45793673, states[0] = -86.935081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54804749, states[0] = -86.933127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63905670, states[0] = -86.975683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72977659, states[0] = -86.985006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81988390, states[0] = -86.981782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91249021, states[0] = -86.850425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100362594, states[0] = -86.942136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109377448, states[0] = -86.946297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118427722, states[0] = -86.960368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127180102, states[0] = -86.713727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136374536, states[0] = -86.941327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145080283, states[0] = -3.195588, states[40]= 0.003664
Saving checkpoint... 
Iteration: 153678384, states[0] = -86.705685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162664918, states[0] = -86.404576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171162636, states[0] = -86.146635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180031489, states[0] = 18.800664, states[40]= 0.005289
Saving checkpoint... 
Iteration: 189197158, states[0] = -86.748626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198168611, states[0] = -86.591248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207145086, states[0] = -69.943973, states[40]= 0.000001
Saving checkpoint... 
Iteration: 215885398, states[0] = -86.942585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224777021, states[0] = -86.872547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233934575, states[0] = -86.956747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242611986, states[0] = -32.817057, states[40]= 0.000314
Saving checkpoint... 
Iteration: 249761775, states[0] = -86.855071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256986937, states[0] = -86.966013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266035647, states[0] = 17.394276, states[40]= 0.005016
Saving checkpoint... 
Iteration: 275033394, states[0] = 18.175408, states[40]= 0.005146
Saving checkpoint... 
Iteration: 284351767, states[0] = -86.927809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293859808, states[0] = -86.931683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302806104, states[0] = -86.898830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312076961, states[0] = -0.949719, states[40]= 0.004019
Saving checkpoint... 
Iteration: 321166108, states[0] = -86.480560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330225204, states[0] = -86.801248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339551470, states[0] = 11.319507, states[40]= 0.004719
Saving checkpoint... 
Iteration: 348764072, states[0] = -86.857667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358107776, states[0] = -28.613344, states[40]= 0.000491
Saving checkpoint... 
Iteration: 367201403, states[0] = -86.756440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376154609, states[0] = -82.463325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385202060, states[0] = -86.757748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394160521, states[0] = -85.705206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403259787, states[0] = -86.852379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412423025, states[0] = -86.953645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421805125, states[0] = -86.897943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430755934, states[0] = -86.847452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439914487, states[0] = -86.951360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449116697, states[0] = -37.531221, states[40]= 0.000169
Saving checkpoint... 
Iteration: 458135815, states[0] = -58.029364, states[40]= 0.000007
Saving checkpoint... 
Iteration: 467134730, states[0] = -56.771833, states[40]= 0.000008
Saving checkpoint... 
Iteration: 476787359, states[0] = -86.882451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485595096, states[0] = -15.974143, states[40]= 0.001306
Saving checkpoint... 
Iteration: 494424075, states[0] = -86.953850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503487201, states[0] = -86.965771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512595977, states[0] = -16.848405, states[40]= 0.001205
Saving checkpoint... 
Iteration: 521506432, states[0] = 24.507965, states[40]= 0.109703
Saving checkpoint... 
Iteration: 530977436, states[0] = -86.964349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540240828, states[0] = -86.826261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549272180, states[0] = -86.866840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558133056, states[0] = -54.865605, states[40]= 0.000011
Saving checkpoint... 
Iteration: 567494257, states[0] = -86.966655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576400937, states[0] = -86.947265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585336431, states[0] = -86.919224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594404894, states[0] = -86.948472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603598299, states[0] = -19.163638, states[40]= 0.000988
Saving checkpoint... 
Iteration: 612026026, states[0] = 20.448955, states[40]= 0.005995
Saving checkpoint... 
Iteration: 621115049, states[0] = -35.873691, states[40]= 0.000213
Saving checkpoint... 
Iteration: 630273911, states[0] = -86.868675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639248835, states[0] = -86.837757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648420778, states[0] = -86.952892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657421512, states[0] = -86.953075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667284197, states[0] = -86.879260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676041800, states[0] = 15.129038, states[40]= 0.004810
Saving checkpoint... 
Iteration: 685496604, states[0] = -86.966863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691676432, states[0] = -86.694779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701320171, states[0] = -86.908845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710535119, states[0] = 17.580989, states[40]= 0.005043
Saving checkpoint... 
Iteration: 719456224, states[0] = -86.960660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728416363, states[0] = -86.951660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737828023, states[0] = -86.913994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746640861, states[0] = -64.196517, states[40]= 0.000002
Saving checkpoint... 
Iteration: 755622352, states[0] = -43.311000, states[40]= 0.000072
Saving checkpoint... 
Iteration: 765114431, states[0] = -35.253970, states[40]= 0.000231
Saving checkpoint... 
Iteration: 774021623, states[0] = 21.522779, states[40]= 0.007344
Saving checkpoint... 
Iteration: 783609459, states[0] = -30.289525, states[40]= 0.000417
Saving checkpoint... 
Iteration: 792373865, states[0] = -86.937402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801509190, states[0] = 23.255084, states[40]= 0.055933
Saving checkpoint... 
Iteration: 810569626, states[0] = 3.174561, states[40]= 0.004459
Saving checkpoint... 
Iteration: 819465562, states[0] = -86.962240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828692692, states[0] = -86.738243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838224141, states[0] = -86.799017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847542977, states[0] = 14.678630, states[40]= 0.004788
Saving checkpoint... 
Iteration: 856728229, states[0] = -86.805993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866358360, states[0] = -86.930548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876154865, states[0] = -82.690862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885465497, states[0] = -86.962180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894677742, states[0] = -86.700579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904291240, states[0] = -86.885746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913145131, states[0] = -69.974226, states[40]= 0.000001
Saving checkpoint... 
Iteration: 921142598, states[0] = -66.477988, states[40]= 0.000002
Saving checkpoint... 
Iteration: 930291167, states[0] = -86.885660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939529461, states[0] = 19.451504, states[40]= 0.005488
Saving checkpoint... 
Iteration: 948733704, states[0] = -86.814909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957659744, states[0] = -85.478585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967085657, states[0] = -7.212248, states[40]= 0.002870
Saving checkpoint... 
Iteration: 976281264, states[0] = -86.876115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985353450, states[0] = -86.928086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994732543, states[0] = -86.813005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004098843, states[0] = -19.706636, states[40]= 0.000946
Saving checkpoint... 
Iteration: 1012956518, states[0] = -86.960498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022300073, states[0] = -86.893378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031934046, states[0] = -86.955850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041141451, states[0] = -64.960530, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1050281764, states[0] = -86.876563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059638958, states[0] = -61.797751, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1069099986, states[0] = -20.848220, states[40]= 0.000869
Saving checkpoint... 
Iteration: 1078153012, states[0] = -80.832818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087328732, states[0] = -86.914183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096818983, states[0] = -86.907734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106220201, states[0] = -86.791855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115476518, states[0] = -86.963779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124344407, states[0] = -86.923306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133456397, states[0] = -86.960386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142719209, states[0] = -86.790041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151840735, states[0] = -86.921265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160460249, states[0] = -86.961066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169825251, states[0] = -86.911892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179503121, states[0] = 32.054859, states[40]= 0.166130
Saving checkpoint... 
Iteration: 1188696010, states[0] = -86.744838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198201327, states[0] = -86.755661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207722959, states[0] = -86.796675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217295412, states[0] = -86.889245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226758635, states[0] = -86.850317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235662973, states[0] = -86.183717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245115829, states[0] = -36.656426, states[40]= 0.000191
Saving checkpoint... 
Iteration: 1254396454, states[0] = -86.945325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263416811, states[0] = -86.951386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272711374, states[0] = -86.775365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282075234, states[0] = 0.095964, states[40]= 0.004157
Saving checkpoint... 
Iteration: 1291451723, states[0] = -86.959386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300631731, states[0] = -53.380433, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1309689503, states[0] = -86.731182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318934163, states[0] = -86.955665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327998291, states[0] = -86.966597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337296965, states[0] = -86.890505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346482295, states[0] = -86.964462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355671938, states[0] = -86.657251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364973503, states[0] = -86.963130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374289002, states[0] = -86.883331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383211195, states[0] = -86.774940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392793195, states[0] = -86.887151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402121585, states[0] = -42.515355, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1411198369, states[0] = -86.749503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420294988, states[0] = -86.888722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429324135, states[0] = -86.910968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438582942, states[0] = -5.052959, states[40]= 0.003313
Saving checkpoint... 
Iteration: 1447424331, states[0] = -86.953210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456907178, states[0] = -86.948518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466163167, states[0] = -86.209868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475503018, states[0] = 32.542038, states[40]= 0.164343
Saving checkpoint... 
Iteration: 1485280516, states[0] = -86.874980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494650767, states[0] = -78.033986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499005430, states[0] = 25.633810, states[40]= 0.135811
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.842553
 - CaMKt in component CaMK (millimolar): 0.006855
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.421951
 - nass in component intracellular_ions (millimolar): 6.422009
 - ki in component intracellular_ions (millimolar): 145.560260
 - kss in component intracellular_ions (millimolar): 145.560241
 - cansr in component intracellular_ions (millimolar): 1.300201
 - cajsr in component intracellular_ions (millimolar): 1.262293
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.008150
 - hf in component INa (dimensionless): 0.661100
 - hs in component INa (dimensionless): 0.661089
 - j in component INa (dimensionless): 0.661025
 - hsp in component INa (dimensionless): 0.413214
 - jp in component INa (dimensionless): 0.660981
 - mL in component INaL (dimensionless): 0.000229
 - hL in component INaL (dimensionless): 0.466135
 - hLp in component INaL (dimensionless): 0.240800
 - a in component Ito (dimensionless): 0.001073
 - iF in component Ito (dimensionless): 0.999466
 - iS in component Ito (dimensionless): 0.578285
 - ap in component Ito (dimensionless): 0.000547
 - iFp in component Ito (dimensionless): 0.999466
 - iSp in component Ito (dimensionless): 0.632810
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935189
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999892
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001552
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.405834
 - xs1 in component IKs (dimensionless): 0.242613
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997021
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:00:06 (52004): called boinc_finish(0)

</stderr_txt>
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