𝕏

Task 55861606

Name HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_913_0
Workunit 26527442
Created 3 Jul 2024, 5:17:41 UTC
Sent 3 Jul 2024, 8:43:23 UTC
Report deadline 6 Jul 2024, 18:19:23 UTC
Received 3 Jul 2024, 23:12:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234616
Run time 3 hours 8 min 43 sec
CPU time 2 hours 58 min 41 sec
Validate state Valid
Credit 60.73
Device peak FLOPS 4.02 GFLOPS
Application version Human ventricular cell models optimization v0.02
aarch64-unknown-linux-gnu
Peak working set size 2.03 MB
Peak swap size 11.08 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_913.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_913_0_r634386929_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_913_0_r634386929_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.415613
     * GNaL_b in INaL: 0.005525
     * Gto_b in Ito: 0.082027
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031617
     * GKs_b in IKs: 0.001922
     * GK1_b in IK1: 0.163784
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 71.001281
     * GKb_b in IKb: 0.003816
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032043
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12247848, states[0] = -94.996339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25738313, states[0] = -94.943977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37892918, states[0] = -95.035335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49761307, states[0] = -94.941424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61869914, states[0] = -95.007867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75326590, states[0] = -94.981220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86448810, states[0] = -95.020211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98070501, states[0] = 2.144777, states[40]= 0.004526
Saving checkpoint... 
Iteration: 109467629, states[0] = -95.019216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121346529, states[0] = -94.983006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133601628, states[0] = -22.073234, states[40]= 0.000844
Saving checkpoint... 
Iteration: 146694518, states[0] = -94.810445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159659191, states[0] = -89.315334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171365384, states[0] = -94.988997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182308997, states[0] = -94.958525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194825529, states[0] = -94.969015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207134580, states[0] = -54.921869, states[40]= 0.000012
Saving checkpoint... 
Iteration: 218119663, states[0] = -39.277267, states[40]= 0.000142
Saving checkpoint... 
Iteration: 232896736, states[0] = -94.999354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246261548, states[0] = -94.915565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257317137, states[0] = -94.963492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269934126, states[0] = -95.008761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282383346, states[0] = -94.994942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293557754, states[0] = 8.187610, states[40]= 0.004904
Saving checkpoint... 
Iteration: 303664931, states[0] = -93.579714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316127566, states[0] = -47.347655, states[40]= 0.000042
Saving checkpoint... 
Iteration: 328296968, states[0] = -94.949009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340850522, states[0] = -94.981749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353288182, states[0] = -94.941754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363595596, states[0] = -16.222412, states[40]= 0.001315
Saving checkpoint... 
Iteration: 375591018, states[0] = -11.972879, states[40]= 0.001960
Saving checkpoint... 
Iteration: 389439043, states[0] = -95.009672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401604090, states[0] = -24.288722, states[40]= 0.000735
Saving checkpoint... 
Iteration: 415536741, states[0] = 16.351257, states[40]= 0.005514
Saving checkpoint... 
Iteration: 428417513, states[0] = -95.004807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438761238, states[0] = -94.915018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452568386, states[0] = 3.367849, states[40]= 0.004631
Saving checkpoint... 
Iteration: 464288660, states[0] = -94.942092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473761439, states[0] = -94.915223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485851625, states[0] = -94.982166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496437906, states[0] = -95.009373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506158346, states[0] = -88.085051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518076923, states[0] = -1.272840, states[40]= 0.004088
Saving checkpoint... 
Iteration: 533615619, states[0] = -35.308156, states[40]= 0.000247
Saving checkpoint... 
Iteration: 544398743, states[0] = -94.999646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555107142, states[0] = -27.188863, states[40]= 0.000598
Saving checkpoint... 
Iteration: 568220609, states[0] = -94.858042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579853519, states[0] = -94.982973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591496310, states[0] = -95.018549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603452989, states[0] = -95.012195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617391580, states[0] = -94.997412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629214429, states[0] = -94.847231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639745345, states[0] = -94.895343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652462250, states[0] = -95.013747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664160824, states[0] = -91.034495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675689894, states[0] = -94.798731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686300584, states[0] = -94.951577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696419018, states[0] = -95.005011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708443156, states[0] = -95.010293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719848168, states[0] = -94.980400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729672076, states[0] = -94.633333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742144055, states[0] = -65.928725, states[40]= 0.000002
Saving checkpoint... 
Iteration: 753816059, states[0] = -94.962430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765451890, states[0] = -95.011898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778189556, states[0] = -94.797910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790084134, states[0] = -6.188277, states[40]= 0.003160
Saving checkpoint... 
Iteration: 801678624, states[0] = -94.759103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812213073, states[0] = -94.844675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824704073, states[0] = -94.827768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834916361, states[0] = -95.004268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846738595, states[0] = -94.885908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857301605, states[0] = -94.952243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869853688, states[0] = -94.982870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881602716, states[0] = -22.983604, states[40]= 0.000798
Saving checkpoint... 
Iteration: 892004751, states[0] = 29.534934, states[40]= 0.148409
Saving checkpoint... 
Iteration: 903103324, states[0] = -23.560983, states[40]= 0.000769
Saving checkpoint... 
Iteration: 914277242, states[0] = -94.931445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925309808, states[0] = -94.958123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936172260, states[0] = -94.640789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946616117, states[0] = -35.790704, states[40]= 0.000231
Saving checkpoint... 
Iteration: 958395991, states[0] = -94.998567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969281461, states[0] = -94.935382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979032638, states[0] = 17.751268, states[40]= 0.005866
Saving checkpoint... 
Iteration: 990391465, states[0] = -94.997145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002149725, states[0] = -73.835274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013003447, states[0] = 34.878200, states[40]= 0.144108
Saving checkpoint... 
Iteration: 1024559037, states[0] = 7.641953, states[40]= 0.004882
Saving checkpoint... 
Iteration: 1036225120, states[0] = -94.865242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048136503, states[0] = -57.032547, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1059319841, states[0] = -94.964659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070950557, states[0] = -95.011467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081593218, states[0] = -13.991483, states[40]= 0.001619
Saving checkpoint... 
Iteration: 1094148514, states[0] = -72.008516, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1103762349, states[0] = -94.915856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116990633, states[0] = -95.017533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130237614, states[0] = -94.884326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140432085, states[0] = -95.007747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151289349, states[0] = -94.942254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162811194, states[0] = -94.958930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174440340, states[0] = -95.009448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184838200, states[0] = -94.975127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197516235, states[0] = 21.998273, states[40]= 0.015415
Saving checkpoint... 
Iteration: 1208286921, states[0] = -94.940128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219532498, states[0] = 17.797278, states[40]= 0.005881
Saving checkpoint... 
Iteration: 1231083716, states[0] = -5.870712, states[40]= 0.003227
Saving checkpoint... 
Iteration: 1241520834, states[0] = 21.062872, states[40]= 0.009239
Saving checkpoint... 
Iteration: 1250477105, states[0] = -95.015645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262098558, states[0] = -19.031460, states[40]= 0.001040
Saving checkpoint... 
Iteration: 1272495294, states[0] = -95.018008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282929105, states[0] = -95.007004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294030898, states[0] = 18.313033, states[40]= 0.006071
Saving checkpoint... 
Iteration: 1303942013, states[0] = -95.009701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314301516, states[0] = -94.951893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323939188, states[0] = -95.009123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336104468, states[0] = -24.647113, states[40]= 0.000718
Saving checkpoint... 
Iteration: 1345953490, states[0] = -95.011825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358539859, states[0] = 15.229670, states[40]= 0.005332
Saving checkpoint... 
Iteration: 1368955455, states[0] = -95.012157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379744526, states[0] = -94.893788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392250336, states[0] = -94.901360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402678773, states[0] = -94.759785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412640132, states[0] = -61.166693, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1424579327, states[0] = -2.786113, states[40]= 0.003836
Saving checkpoint... 
Iteration: 1435073166, states[0] = 0.890282, states[40]= 0.004384
Saving checkpoint... 
Iteration: 1445964511, states[0] = -95.013623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456446564, states[0] = -95.010487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470099850, states[0] = -20.259834, states[40]= 0.000951
Saving checkpoint... 
Iteration: 1480075106, states[0] = -0.198646, states[40]= 0.004245
Saving checkpoint... 
Iteration: 1493509828, states[0] = 23.454265, states[40]= 0.055040
Saving checkpoint... 
Iteration: 1503105900, states[0] = -41.590416, states[40]= 0.000096
Saving checkpoint... 
Iteration: 1513206496, states[0] = 27.345179, states[40]= 0.101917
Saving checkpoint... 
Iteration: 1523002548, states[0] = -95.154829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1534664243, states[0] = -95.079226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1544969869, states[0] = -95.257303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556186628, states[0] = -23.465336, states[40]= 0.000796
Saving checkpoint... 
Iteration: 1566909295, states[0] = 24.566627, states[40]= 0.061559
Saving checkpoint... 
Iteration: 1577793807, states[0] = -31.647123, states[40]= 0.000382
Saving checkpoint... 
Iteration: 1590267626, states[0] = -95.268748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602923184, states[0] = 19.781939, states[40]= 0.009125
Saving checkpoint... 
Iteration: 1614177878, states[0] = -95.136511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1624269397, states[0] = -5.916908, states[40]= 0.003623
Saving checkpoint... 
Iteration: 1634338450, states[0] = -95.241596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645122219, states[0] = -95.220350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1656563228, states[0] = -95.268322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667829892, states[0] = -78.376016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679705412, states[0] = 29.065325, states[40]= 0.122631
Saving checkpoint... 
Iteration: 1689896039, states[0] = -95.294117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699775387, states[0] = -95.279149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710055196, states[0] = 4.247150, states[40]= 0.005334
Saving checkpoint... 
Iteration: 1721201352, states[0] = -40.348915, states[40]= 0.000124
Saving checkpoint... 
Iteration: 1732781924, states[0] = -95.284307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742653234, states[0] = -95.258956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753886294, states[0] = -23.736732, states[40]= 0.000780
Saving checkpoint... 
Iteration: 1766163121, states[0] = -0.917167, states[40]= 0.004663
Saving checkpoint... 
Iteration: 1778045017, states[0] = -95.250106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790657064, states[0] = -95.262798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1801242121, states[0] = -94.956371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813647099, states[0] = -75.048560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1824506419, states[0] = 25.861293, states[40]= 0.119234
Saving checkpoint... 
Iteration: 1835898591, states[0] = -95.022695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847859546, states[0] = -95.001646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859504310, states[0] = 30.934348, states[40]= 0.153058
Saving checkpoint... 
Iteration: 1870153271, states[0] = -80.802558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1881214224, states[0] = -94.852458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892921292, states[0] = -95.009195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903989511, states[0] = -95.020045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1915580230, states[0] = -3.468340, states[40]= 0.003713
Saving checkpoint... 
Iteration: 1926540280, states[0] = 15.051085, states[40]= 0.005311
Saving checkpoint... 
Iteration: 1936455050, states[0] = -95.012909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1948570048, states[0] = 2.513282, states[40]= 0.004556
Saving checkpoint... 
Iteration: 1960449128, states[0] = -95.011208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1973670103, states[0] = -94.521062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1986100003, states[0] = -20.421530, states[40]= 0.000940
Saving checkpoint... 
Iteration: 1996788999, states[0] = -94.941589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008415116, states[0] = -95.003323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2018390633, states[0] = -94.996303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029393746, states[0] = -94.997243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041163687, states[0] = -93.060502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050501312, states[0] = 49.109893, states[40]= 0.047302
Saving checkpoint... 
Iteration: 2062025640, states[0] = 19.866543, states[40]= 0.007068
Saving checkpoint... 
Iteration: 2073793580, states[0] = -94.945174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086855150, states[0] = -94.982734, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.893880
 - CaMKt in component CaMK (millimolar): 0.006905
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.559624
 - nass in component intracellular_ions (millimolar): 6.559684
 - ki in component intracellular_ions (millimolar): 145.418764
 - kss in component intracellular_ions (millimolar): 145.418745
 - cansr in component intracellular_ions (millimolar): 1.309144
 - cajsr in component intracellular_ions (millimolar): 1.271379
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003621
 - hf in component INa (dimensionless): 0.879862
 - hs in component INa (dimensionless): 0.879858
 - j in component INa (dimensionless): 0.879829
 - hsp in component INa (dimensionless): 0.725570
 - jp in component INa (dimensionless): 0.879810
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709943
 - hLp in component INaL (dimensionless): 0.452466
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.622284
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.697340
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936074
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001594
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331534
 - xs1 in component IKs (dimensionless): 0.239318
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997339
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:32:12 (2774978): called boinc_finish(0)

</stderr_txt>
]]>


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