𝕏

Task 55861439

Name HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pieske_333-conf_212_1
Workunit 26527358
Created 3 Jul 2024, 5:17:36 UTC
Sent 3 Jul 2024, 8:40:55 UTC
Report deadline 6 Jul 2024, 8:40:55 UTC
Received 3 Jul 2024, 15:48:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232551
Run time 1 hours 6 min 35 sec
CPU time 43 min 4 sec
Validate state Valid
Credit 39.94
Device peak FLOPS 4.91 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.75 MB
Peak swap size 392.01 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pieske_333-conf_212.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pieske_333-conf_212_1_r549718749_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pieske_333-conf_212_1_r549718749_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.174686
     * GNaL_b in INaL: 0.005699
     * Gto_b in Ito: 0.086162
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031949
     * GKs_b in IKs: 0.001914
     * GK1_b in IK1: 0.165449
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.996899
     * GKb_b in IKb: 0.003786
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028635
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 16688168, states[0] = 16.855392, states[40]= 0.009904
Saving checkpoint... 
Iteration: 33605827, states[0] = -85.580520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44393537, states[0] = -21.751850, states[40]= 0.001079
Saving checkpoint... 
Iteration: 60928435, states[0] = -75.935686, states[40]= 0.000001
Saving checkpoint... 
Iteration: 78587664, states[0] = -66.221529, states[40]= 0.000003
Saving checkpoint... 
Iteration: 99798625, states[0] = -87.752610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118473251, states[0] = -87.787267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130360152, states[0] = 6.401774, states[40]= 0.007060
Saving checkpoint... 
Iteration: 152439337, states[0] = -87.623306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171443074, states[0] = -87.684896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188943921, states[0] = -87.700390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201508413, states[0] = 13.924593, states[40]= 0.008235
Saving checkpoint... 
Iteration: 218295052, states[0] = -87.782705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236253075, states[0] = -86.182919, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pieske_333-conf_212.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pieske_333-conf_212_1_r549718749_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pieske_333-conf_212_1_r549718749_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.174686
     * GNaL_b in INaL: 0.005699
     * Gto_b in Ito: 0.086162
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031949
     * GKs_b in IKs: 0.001914
     * GK1_b in IK1: 0.165449
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.996899
     * GKb_b in IKb: 0.003786
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028635
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 236253075
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.182919 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 254724453, states[0] = -47.941341, states[40]= 0.000052
Saving checkpoint... 
Iteration: 272787936, states[0] = -87.777122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292953140, states[0] = -87.778978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311141998, states[0] = 24.969393, states[40]= 0.097155
Saving checkpoint... 
Iteration: 329509722, states[0] = 4.178969, states[40]= 0.006756
Saving checkpoint... 
Iteration: 353907235, states[0] = -85.832897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372909603, states[0] = -87.143837, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pieske_333-conf_212.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pieske_333-conf_212_1_r549718749_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pieske_333-conf_212_1_r549718749_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.174686
     * GNaL_b in INaL: 0.005699
     * Gto_b in Ito: 0.086162
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031949
     * GKs_b in IKs: 0.001914
     * GK1_b in IK1: 0.165449
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.996899
     * GKb_b in IKb: 0.003786
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028635
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 372909603
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -87.143837 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 390825770, states[0] = 12.132640, states[40]= 0.007857
Saving checkpoint... 
Iteration: 408541284, states[0] = -46.366533, states[40]= 0.000066
Saving checkpoint... 
Iteration: 426414934, states[0] = -87.663220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441473964, states[0] = 19.220649, states[40]= 0.013017
Saving checkpoint... 
Iteration: 458922115, states[0] = -87.724533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478108406, states[0] = -87.801362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497128473, states[0] = 21.761721, states[40]= 0.034304
Saving checkpoint... 
Iteration: 509542933, states[0] = -63.693127, states[40]= 0.000005
Saving checkpoint... 
Iteration: 526721769, states[0] = -84.872934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546700695, states[0] = -55.765052, states[40]= 0.000016
Saving checkpoint... 
Iteration: 564655042, states[0] = 2.341947, states[40]= 0.006467
Saving checkpoint... 
Iteration: 579404635, states[0] = -87.698692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596887811, states[0] = -87.230883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619198480, states[0] = -63.452180, states[40]= 0.000005
Saving checkpoint... 
Iteration: 639900371, states[0] = -87.707774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658375009, states[0] = -84.672833, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pieske_333-conf_212.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pieske_333-conf_212_1_r549718749_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pieske_333-conf_212_1_r549718749_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.174686
     * GNaL_b in INaL: 0.005699
     * Gto_b in Ito: 0.086162
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031949
     * GKs_b in IKs: 0.001914
     * GK1_b in IK1: 0.165449
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.996899
     * GKb_b in IKb: 0.003786
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028635
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 658375009
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.672833 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 673734759, states[0] = -87.727686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688471112, states[0] = 6.312685, states[40]= 0.007049
Saving checkpoint... 
Iteration: 708125324, states[0] = 13.384860, states[40]= 0.008105
Saving checkpoint... 
Iteration: 719767552, states[0] = 25.276680, states[40]= 0.101452
Saving checkpoint... 
Iteration: 742174893, states[0] = -46.799819, states[40]= 0.000062
Saving checkpoint... 
Iteration: 758189876, states[0] = -72.406869, states[40]= 0.000001
Saving checkpoint... 
Iteration: 775271944, states[0] = 20.021274, states[40]= 0.016116
Saving checkpoint... 
Iteration: 787629610, states[0] = 4.954527, states[40]= 0.006866
Saving checkpoint... 
Iteration: 805213753, states[0] = -87.688776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820326693, states[0] = -37.020965, states[40]= 0.000237
Saving checkpoint... 
Iteration: 834656045, states[0] = -33.508847, states[40]= 0.000361
Saving checkpoint... 
Iteration: 853406404, states[0] = -87.807415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869792711, states[0] = 0.979444, states[40]= 0.006221
Saving checkpoint... 
Iteration: 887193294, states[0] = -87.360425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906282900, states[0] = 6.132299, states[40]= 0.007025
Saving checkpoint... 
Iteration: 933189601, states[0] = -87.433664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956278929, states[0] = 5.334979, states[40]= 0.006919
Saving checkpoint... 
Iteration: 983393877, states[0] = -87.808623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019090315, states[0] = 15.619360, states[40]= 0.008795
Saving checkpoint... 
Iteration: 1039668628, states[0] = -83.179318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058785881, states[0] = -13.224049, states[40]= 0.002444
Saving checkpoint... 
Iteration: 1081903405, states[0] = 21.729327, states[40]= 0.033753
Saving checkpoint... 
Iteration: 1109709165, states[0] = -87.792156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130091774, states[0] = 7.677790, states[40]= 0.007224
Saving checkpoint... 
Iteration: 1146283015, states[0] = -21.572878, states[40]= 0.001102
Saving checkpoint... 
Iteration: 1170136069, states[0] = -52.453422, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1196583870, states[0] = 8.576122, states[40]= 0.007339
Saving checkpoint... 
Iteration: 1221597849, states[0] = -6.480368, states[40]= 0.004329
Saving checkpoint... 
Iteration: 1237246033, states[0] = 8.882899, states[40]= 0.007379
Saving checkpoint... 
Iteration: 1261892331, states[0] = 19.043118, states[40]= 0.012539
Saving checkpoint... 
Iteration: 1290708184, states[0] = 30.100477, states[40]= 0.128315
Saving checkpoint... 
Iteration: 1323833756, states[0] = -87.715224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351717323, states[0] = 18.764508, states[40]= 0.011894
Saving checkpoint... 
Iteration: 1373277963, states[0] = -46.126547, states[40]= 0.000068
Saving checkpoint... 
Iteration: 1392999484, states[0] = -87.740109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415293959, states[0] = -77.861633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438171236, states[0] = -87.774964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455741308, states[0] = -6.736008, states[40]= 0.004253
Saving checkpoint... 
Iteration: 1477382334, states[0] = 13.018162, states[40]= 0.008026
Saving checkpoint... 
Iteration: 1495116307, states[0] = -72.634915, states[40]= 0.000001
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.705080
 - CaMKt in component CaMK (millimolar): 0.042894
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 6.987976
 - nass in component intracellular_ions (millimolar): 6.988125
 - ki in component intracellular_ions (millimolar): 144.930914
 - kss in component intracellular_ions (millimolar): 144.930882
 - cansr in component intracellular_ions (millimolar): 1.625773
 - cajsr in component intracellular_ions (millimolar): 1.191108
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007473
 - hf in component INa (dimensionless): 0.692099
 - hs in component INa (dimensionless): 0.691860
 - j in component INa (dimensionless): 0.681343
 - hsp in component INa (dimensionless): 0.446919
 - jp in component INa (dimensionless): 0.654864
 - mL in component INaL (dimensionless): 0.000195
 - hL in component INaL (dimensionless): 0.293136
 - hLp in component INaL (dimensionless): 0.136262
 - a in component Ito (dimensionless): 0.001013
 - iF in component Ito (dimensionless): 0.999540
 - iS in component Ito (dimensionless): 0.175695
 - ap in component Ito (dimensionless): 0.000516
 - iFp in component Ito (dimensionless): 0.999540
 - iSp in component Ito (dimensionless): 0.212683
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.804509
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966997
 - jca in component ICaL (dimensionless): 0.947915
 - ffp in component ICaL (dimensionless): 0.999863
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009523
 - xrf in component IKr (dimensionless): 0.028458
 - xrs in component IKr (dimensionless): 0.785349
 - xs1 in component IKs (dimensionless): 0.458869
 - xs2 in component IKs (dimensionless): 0.001184
 - xk1 in component IK1 (dimensionless): 0.996810
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:48:34 (720): called boinc_finish(0)

</stderr_txt>
]]>