𝕏

Task 55861009

Name HuVeMOp_20240703071643700359_ORdGradInc_k_26-Coppini_5000-conf_310_1
Workunit 26527143
Created 3 Jul 2024, 5:17:21 UTC
Sent 3 Jul 2024, 8:38:06 UTC
Report deadline 6 Jul 2024, 8:38:06 UTC
Received 3 Jul 2024, 23:07:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 39 min 16 sec
CPU time 1 hours 59 min 26 sec
Validate state Valid
Credit 43.62
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.49 MB
Peak swap size 32.60 GB
Peak disk usage 1.56 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Coppini_5000-conf_310.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Coppini_5000-conf_310_1_r1087272072_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Coppini_5000-conf_310_1_r1087272072_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.180044
     * GNaL_b in INaL: 0.005491
     * Gto_b in Ito: 0.081729
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031777
     * GKs_b in IKs: 0.001898
     * GK1_b in IK1: 0.167498
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.273974
     * GKb_b in IKb: 0.003785
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030077
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 7349060, states[0] = -94.707716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17430391, states[0] = -94.630990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26824854, states[0] = -94.591406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36547362, states[0] = -94.566856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46548768, states[0] = -94.549009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57306827, states[0] = -94.530065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67160276, states[0] = -94.523054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75931558, states[0] = -94.534002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85761291, states[0] = -94.530247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95959661, states[0] = -94.526041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106148691, states[0] = -94.520038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116476801, states[0] = -94.512526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126762100, states[0] = -94.507582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136901192, states[0] = -94.505141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146458095, states[0] = -94.509333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155992622, states[0] = -94.516949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164533738, states[0] = -94.502098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173388620, states[0] = -94.517612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182266280, states[0] = -94.499850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191235490, states[0] = -94.510882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200513668, states[0] = -94.490717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210163243, states[0] = -49.635071, states[40]= 0.000108
Saving checkpoint... 
Iteration: 220107709, states[0] = -4.526641, states[40]= 0.003714
Saving checkpoint... 
Iteration: 230248668, states[0] = -94.173515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240369828, states[0] = -94.408375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249349362, states[0] = -94.501782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258757451, states[0] = -94.509579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268811625, states[0] = -94.508574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278242341, states[0] = -94.515670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288135373, states[0] = -94.510251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297310746, states[0] = -94.498275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307794847, states[0] = -94.295606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319024759, states[0] = -94.505159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330577637, states[0] = -94.503308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341412712, states[0] = -94.506743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351246127, states[0] = -94.509535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361107729, states[0] = -94.512152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370821779, states[0] = -94.516259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380185152, states[0] = -70.981609, states[40]= 0.000003
Saving checkpoint... 
Iteration: 388957864, states[0] = -94.506013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397745490, states[0] = -94.162627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406634732, states[0] = -94.503662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415287575, states[0] = -94.279522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424334673, states[0] = -94.501541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433794914, states[0] = -94.508590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443462626, states[0] = -94.514770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454460494, states[0] = -94.500426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464909397, states[0] = -94.497565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472348189, states[0] = -94.497873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483466662, states[0] = -94.514675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494280717, states[0] = -94.502010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504534848, states[0] = -94.499816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514607390, states[0] = -94.499292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524729159, states[0] = -94.498506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535633738, states[0] = -94.509837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547102238, states[0] = -94.499305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558367196, states[0] = -94.515916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569244948, states[0] = -94.502322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579005628, states[0] = -94.505195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587607143, states[0] = -4.113787, states[40]= 0.003795
Saving checkpoint... 
Iteration: 596201505, states[0] = -94.510173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605038684, states[0] = 23.907002, states[40]= 0.002198
Saving checkpoint... 
Iteration: 614394117, states[0] = -94.500872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623482716, states[0] = -94.514306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632051682, states[0] = -94.499605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641741645, states[0] = -94.502307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652186609, states[0] = -94.498679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659747801, states[0] = -94.498303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670225734, states[0] = -94.092529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680361221, states[0] = -94.398571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690791535, states[0] = -94.515940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701476846, states[0] = -94.505516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711668511, states[0] = -94.503056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721493364, states[0] = -94.505269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730898709, states[0] = -94.515486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739671299, states[0] = -94.498716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747979363, states[0] = -94.478344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755734840, states[0] = -94.515039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763704342, states[0] = -94.510005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772308421, states[0] = -94.497882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781490312, states[0] = -94.505271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791612254, states[0] = -94.503664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798752461, states[0] = -94.509094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809514607, states[0] = -94.499759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820088961, states[0] = 6.191209, states[40]= 0.004645
Saving checkpoint... 
Iteration: 830525628, states[0] = -94.492597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840942956, states[0] = -94.514809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851332785, states[0] = -94.507655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860951956, states[0] = -94.514656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870982858, states[0] = -94.514135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880851765, states[0] = -94.515802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890535213, states[0] = -94.494847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899893055, states[0] = -94.497349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908671461, states[0] = -94.510530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917330437, states[0] = -94.497663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926213168, states[0] = -94.509729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935277477, states[0] = -94.255051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944695388, states[0] = -94.498425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954370311, states[0] = -94.500850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964425644, states[0] = -94.500363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974599705, states[0] = -94.499031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984969235, states[0] = -94.496921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995029316, states[0] = 25.926428, states[40]= 0.001928
Saving checkpoint... 
Iteration: 1005144213, states[0] = -33.517581, states[40]= 0.000959
Saving checkpoint... 
Iteration: 1015441838, states[0] = -94.461320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025736777, states[0] = -94.514903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036178789, states[0] = -94.510303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046280458, states[0] = -94.508424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056217811, states[0] = -94.509554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065477099, states[0] = -94.477264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074104958, states[0] = -94.503561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082403194, states[0] = -94.497174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090750699, states[0] = -94.515161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099431086, states[0] = -94.500226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108626488, states[0] = -94.511261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118503325, states[0] = -94.513604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128334967, states[0] = -94.515707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137122959, states[0] = -94.498762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147505135, states[0] = 29.341444, states[40]= 0.234764
Saving checkpoint... 
Iteration: 1157932792, states[0] = -94.456241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168500220, states[0] = -94.513626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178935383, states[0] = -94.505799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189245819, states[0] = -94.501891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199313443, states[0] = -94.501210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209031741, states[0] = -94.504410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218001362, states[0] = -94.485567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225540622, states[0] = -94.495827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233260853, states[0] = -94.515239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241703711, states[0] = -94.502303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250709062, states[0] = -94.513906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260306735, states[0] = -94.318625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270076981, states[0] = 11.509129, states[40]= 0.004320
Saving checkpoint... 
Iteration: 1280901345, states[0] = -94.515081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291804165, states[0] = -94.501236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302546184, states[0] = 21.939801, states[40]= 0.002569
Saving checkpoint... 
Iteration: 1312871781, states[0] = -94.409297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319950365, states[0] = -94.496782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330725758, states[0] = -94.514401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341695697, states[0] = -94.502323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352304070, states[0] = -94.497510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362380187, states[0] = -94.497099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371948129, states[0] = -94.499899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380983125, states[0] = -94.513784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390170667, states[0] = -56.213446, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1399248314, states[0] = -94.501722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408513503, states[0] = -94.513222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417655445, states[0] = -42.811557, states[40]= 0.000298
Saving checkpoint... 
Iteration: 1426750325, states[0] = -94.501682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437301045, states[0] = -94.497469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447820059, states[0] = -94.342004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458214431, states[0] = -94.513956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468485490, states[0] = -94.513683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479345912, states[0] = -94.500714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489799004, states[0] = -94.497445, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.372404
 - CaMKt in component CaMK (millimolar): 0.001121
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.338155
 - nass in component intracellular_ions (millimolar): 6.338241
 - ki in component intracellular_ions (millimolar): 145.587648
 - kss in component intracellular_ions (millimolar): 145.587638
 - cansr in component intracellular_ions (millimolar): 1.564587
 - cajsr in component intracellular_ions (millimolar): 1.564621
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003817
 - hf in component INa (dimensionless): 0.870505
 - hs in component INa (dimensionless): 0.870505
 - j in component INa (dimensionless): 0.870506
 - hsp in component INa (dimensionless): 0.708209
 - jp in component INa (dimensionless): 0.870506
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.714987
 - hLp in component INaL (dimensionless): 0.522847
 - a in component Ito (dimensionless): 0.000646
 - iF in component Ito (dimensionless): 0.999857
 - iS in component Ito (dimensionless): 0.997773
 - ap in component Ito (dimensionless): 0.000329
 - iFp in component Ito (dimensionless): 0.999857
 - iSp in component Ito (dimensionless): 0.999265
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998879
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002982
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001765
 - xs1 in component IKs (dimensionless): 0.022565
 - xs2 in component IKs (dimensionless): 0.000093
 - xk1 in component IK1 (dimensionless): 0.997473
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:08:44 (86599): called boinc_finish(0)

</stderr_txt>
]]>


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