𝕏

Task 55859505

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_ENDO_1000-conf_895_1
Workunit 26526391
Created 3 Jul 2024, 5:16:39 UTC
Sent 3 Jul 2024, 8:30:03 UTC
Report deadline 6 Jul 2024, 8:30:03 UTC
Received 3 Jul 2024, 15:01:28 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234246
Run time 1 hours 59 min 30 sec
CPU time 1 hours 52 min 48 sec
Validate state Valid
Credit 43.66
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.20 MB
Peak swap size 6.21 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_ENDO_1000-conf_895.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_ENDO_1000-conf_895_1_r1486632307_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_ENDO_1000-conf_895_1_r1486632307_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 102.680014
     * GNaL_b in INaL: 0.006178
     * Gto_b in Ito: 0.083076
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032289
     * GKs_b in IKs: 0.001950
     * GK1_b in IK1: 0.159843
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 71.106229
     * GKb_b in IKb: 0.003815
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036470
     * celltype in environment: 0.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 4673350, states[0] = -85.219696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 12777098, states[0] = -94.198114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21136774, states[0] = -37.105791, states[40]= 0.000837
Saving checkpoint... 
Iteration: 29450279, states[0] = -94.374389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37633431, states[0] = -34.204679, states[40]= 0.001142
Saving checkpoint... 
Iteration: 42814381, states[0] = -94.242542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50994052, states[0] = -94.397500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59224329, states[0] = -93.946066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67510106, states[0] = 32.179460, states[40]= 0.058410
Saving checkpoint... 
Iteration: 75866273, states[0] = -94.330521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84290079, states[0] = -94.201045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92387971, states[0] = -94.354434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100510595, states[0] = 32.227565, states[40]= 0.049413
Saving checkpoint... 
Iteration: 108543384, states[0] = 24.772321, states[40]= 0.000233
Saving checkpoint... 
Iteration: 116618372, states[0] = -21.257582, states[40]= 0.001393
Saving checkpoint... 
Iteration: 124693040, states[0] = -93.443012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132749965, states[0] = -94.074746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140634647, states[0] = -36.322062, states[40]= 0.000919
Saving checkpoint... 
Iteration: 147482119, states[0] = -94.407876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155345648, states[0] = -94.311109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163393191, states[0] = -94.361976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171540262, states[0] = 25.978112, states[40]= 0.000188
Saving checkpoint... 
Iteration: 179550277, states[0] = 21.937541, states[40]= 0.000365
Saving checkpoint... 
Iteration: 187516884, states[0] = 32.554080, states[40]= 0.005575
Saving checkpoint... 
Iteration: 195557432, states[0] = 18.898532, states[40]= 0.000580
Saving checkpoint... 
Iteration: 203841832, states[0] = -94.305735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212126071, states[0] = -28.490803, states[40]= 0.001495
Saving checkpoint... 
Iteration: 220418225, states[0] = -94.379620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228540052, states[0] = 26.056848, states[40]= 0.000185
Saving checkpoint... 
Iteration: 236810000, states[0] = -94.250789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245176789, states[0] = -81.459404, states[40]= 0.000001
Saving checkpoint... 
Iteration: 253466652, states[0] = -94.402479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261257098, states[0] = -94.102316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269569014, states[0] = 13.734081, states[40]= 0.001155
Saving checkpoint... 
Iteration: 277705259, states[0] = -93.839155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285779035, states[0] = -94.174501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294079944, states[0] = 8.461154, states[40]= 0.002004
Saving checkpoint... 
Iteration: 302395782, states[0] = -94.363108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310711910, states[0] = -93.886225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318886028, states[0] = -94.354792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327215405, states[0] = -93.906763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335506864, states[0] = 32.051418, states[40]= 0.180870
Saving checkpoint... 
Iteration: 343798811, states[0] = -94.225374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352485859, states[0] = -94.407658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361180576, states[0] = -86.749618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369818679, states[0] = -94.266381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377723242, states[0] = -93.949265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384944280, states[0] = -94.392044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393269632, states[0] = -94.144565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401601657, states[0] = -5.373342, states[40]= 0.002999
Saving checkpoint... 
Iteration: 409825546, states[0] = -94.278225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418211532, states[0] = -93.882782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426646439, states[0] = -47.523010, states[40]= 0.000247
Saving checkpoint... 
Iteration: 434898342, states[0] = -94.363778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443342197, states[0] = -94.303964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451664389, states[0] = -65.480590, states[40]= 0.000016
Saving checkpoint... 
Iteration: 459825328, states[0] = -94.277344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467983740, states[0] = -94.405888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476260160, states[0] = -94.111362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483956505, states[0] = -94.396333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492276528, states[0] = -94.165017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500600483, states[0] = -4.395876, states[40]= 0.003091
Saving checkpoint... 
Iteration: 508958547, states[0] = -94.396894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517171599, states[0] = -74.081973, states[40]= 0.000004
Saving checkpoint... 
Iteration: 525450812, states[0] = -94.393546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533923454, states[0] = -94.379686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542266022, states[0] = -94.131122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550650456, states[0] = -51.436644, states[40]= 0.000144
Saving checkpoint... 
Iteration: 558934255, states[0] = -94.385382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567343176, states[0] = -94.304099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575575921, states[0] = 10.465758, states[40]= 0.001660
Saving checkpoint... 
Iteration: 583797888, states[0] = -94.220788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591999612, states[0] = -94.408853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599734600, states[0] = -94.003858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608081712, states[0] = 7.551723, states[40]= 0.002164
Saving checkpoint... 
Iteration: 616454486, states[0] = -94.394178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624881336, states[0] = -94.347470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633194611, states[0] = -93.572049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641441034, states[0] = -94.387935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649689470, states[0] = -92.886159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658119588, states[0] = -22.487322, states[40]= 0.001420
Saving checkpoint... 
Iteration: 666536488, states[0] = 27.404204, states[40]= 0.000150
Saving checkpoint... 
Iteration: 674951956, states[0] = -94.392532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683259222, states[0] = -94.105852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691523963, states[0] = 31.379935, states[40]= 0.000534
Saving checkpoint... 
Iteration: 699955422, states[0] = -94.393723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708283238, states[0] = -94.182143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715919537, states[0] = -94.375516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724051076, states[0] = 21.602663, states[40]= 0.000385
Saving checkpoint... 
Iteration: 732261197, states[0] = -94.112463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740686653, states[0] = -91.921783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749068075, states[0] = 14.167681, states[40]= 0.001096
Saving checkpoint... 
Iteration: 757358524, states[0] = -94.322096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765508839, states[0] = 31.949031, states[40]= 0.091126
Saving checkpoint... 
Iteration: 773818156, states[0] = -94.261320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782151832, states[0] = -52.779743, states[40]= 0.000118
Saving checkpoint... 
Iteration: 790618489, states[0] = -21.446276, states[40]= 0.001393
Saving checkpoint... 
Iteration: 798971186, states[0] = -94.398605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807289847, states[0] = -94.198776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815521630, states[0] = 31.898080, states[40]= 0.001116
Saving checkpoint... 
Iteration: 823727174, states[0] = -93.965058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831841467, states[0] = -94.298994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839891294, states[0] = -94.354057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848054769, states[0] = 20.042205, states[40]= 0.000489
Saving checkpoint... 
Iteration: 856450203, states[0] = -94.389957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864711461, states[0] = -93.877727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873003497, states[0] = 38.155200, states[40]= 0.572361
Saving checkpoint... 
Iteration: 881335235, states[0] = -94.289218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889709350, states[0] = -93.863851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898081410, states[0] = 7.710361, states[40]= 0.002137
Saving checkpoint... 
Iteration: 906484757, states[0] = -94.401779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914789311, states[0] = -94.196302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922978575, states[0] = -94.399761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931181494, states[0] = -87.829145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938968280, states[0] = -94.396194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947086759, states[0] = 4.819963, states[40]= 0.002622
Saving checkpoint... 
Iteration: 955444655, states[0] = -94.386482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963919459, states[0] = -94.372973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972345820, states[0] = -94.303685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980851666, states[0] = -94.311356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989140923, states[0] = -42.219704, states[40]= 0.000484
Saving checkpoint... 
Iteration: 997461892, states[0] = -94.393276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005774825, states[0] = -94.154645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013973563, states[0] = -94.397240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022135763, states[0] = -37.387743, states[40]= 0.000827
Saving checkpoint... 
Iteration: 1030559085, states[0] = 18.182303, states[40]= 0.000643
Saving checkpoint... 
Iteration: 1036310432, states[0] = -94.243615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044542466, states[0] = 25.115482, states[40]= 0.000217
Saving checkpoint... 
Iteration: 1052677152, states[0] = -81.963327, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1060863749, states[0] = -94.325083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069020142, states[0] = 32.169726, states[40]= 0.001831
Saving checkpoint... 
Iteration: 1077274265, states[0] = -94.152203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085645806, states[0] = -46.899968, states[40]= 0.000268
Saving checkpoint... 
Iteration: 1093962019, states[0] = -94.392354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102332962, states[0] = -94.283437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110502263, states[0] = 44.761917, states[40]= 0.793989
Saving checkpoint... 
Iteration: 1118805942, states[0] = -94.233409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126989761, states[0] = -94.400964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135158520, states[0] = -59.379336, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1143526043, states[0] = 30.841210, states[40]= 0.000300
Saving checkpoint... 
Iteration: 1151724572, states[0] = -93.948280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160073759, states[0] = 11.511753, states[40]= 0.001490
Saving checkpoint... 
Iteration: 1168187370, states[0] = -92.220936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176608853, states[0] = -12.015879, states[40]= 0.002031
Saving checkpoint... 
Iteration: 1185013165, states[0] = 32.539764, states[40]= 0.020232
Saving checkpoint... 
Iteration: 1193337132, states[0] = -94.288957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201761668, states[0] = -94.109345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210176215, states[0] = -80.577791, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1218575704, states[0] = 10.574479, states[40]= 0.001643
Saving checkpoint... 
Iteration: 1227071225, states[0] = 12.710486, states[40]= 0.001304
Saving checkpoint... 
Iteration: 1235506706, states[0] = 32.110481, states[40]= 0.190987
Saving checkpoint... 
Iteration: 1244141267, states[0] = -42.542674, states[40]= 0.000465
Saving checkpoint... 
Iteration: 1252617620, states[0] = -20.612345, states[40]= 0.001380
Saving checkpoint... 
Iteration: 1261199489, states[0] = -93.751353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269749211, states[0] = -94.061298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278210762, states[0] = -93.869052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286309168, states[0] = -94.238492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294839636, states[0] = -94.291657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303515076, states[0] = 32.617508, states[40]= 0.010419
Saving checkpoint... 
Iteration: 1311972872, states[0] = -94.394017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320447343, states[0] = -94.384034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328924314, states[0] = -94.372189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337512893, states[0] = 32.516837, states[40]= 0.022238
Saving checkpoint... 
Iteration: 1346048207, states[0] = 22.796392, states[40]= 0.000318
Saving checkpoint... 
Iteration: 1354405768, states[0] = -94.360016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362839898, states[0] = -94.291354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371327677, states[0] = -94.272114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379864878, states[0] = -94.323128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388299324, states[0] = -94.215966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396585831, states[0] = 5.342361, states[40]= 0.002540
Saving checkpoint... 
Iteration: 1404958830, states[0] = -94.388001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413546068, states[0] = 23.671998, states[40]= 0.000276
Saving checkpoint... 
Iteration: 1422113884, states[0] = -16.980863, states[40]= 0.001476
Saving checkpoint... 
Iteration: 1430707981, states[0] = -93.848737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439178050, states[0] = -83.256785, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1447853219, states[0] = -94.308621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456449111, states[0] = -94.383450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465030984, states[0] = 29.337676, states[40]= 0.000140
Saving checkpoint... 
Iteration: 1473552777, states[0] = 20.889777, states[40]= 0.000430
Saving checkpoint... 
Iteration: 1482153101, states[0] = -54.012524, states[40]= 0.000099
Saving checkpoint... 
Iteration: 1490620746, states[0] = -23.564035, states[40]= 0.001455
Saving checkpoint... 
Iteration: 1498915417, states[0] = -94.365065, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.275703
 - CaMKt in component CaMK (millimolar): 0.017638
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 7.003007
 - nass in component intracellular_ions (millimolar): 7.003130
 - ki in component intracellular_ions (millimolar): 144.777811
 - kss in component intracellular_ions (millimolar): 144.777791
 - cansr in component intracellular_ions (millimolar): 1.935572
 - cajsr in component intracellular_ions (millimolar): 1.891129
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003855
 - hf in component INa (dimensionless): 0.868705
 - hs in component INa (dimensionless): 0.868694
 - j in component INa (dimensionless): 0.868626
 - hsp in component INa (dimensionless): 0.704856
 - jp in component INa (dimensionless): 0.868577
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.686966
 - hLp in component INaL (dimensionless): 0.417196
 - a in component Ito (dimensionless): 0.000650
 - iF in component Ito (dimensionless): 0.999855
 - iS in component Ito (dimensionless): 0.596131
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999855
 - iSp in component Ito (dimensionless): 0.662249
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.899783
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999756
 - jca in component ICaL (dimensionless): 0.999965
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004557
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.398407
 - xs1 in component IKs (dimensionless): 0.292056
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997497
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:00:59 (15880): called boinc_finish(0)

</stderr_txt>
]]>


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