𝕏

Task 55857572

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_MID_3000-conf_782_0
Workunit 26525425
Created 3 Jul 2024, 5:15:41 UTC
Sent 3 Jul 2024, 8:13:09 UTC
Report deadline 6 Jul 2024, 8:13:09 UTC
Received 5 Jul 2024, 6:21:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 51 min 34 sec
CPU time 1 hours 41 min 21 sec
Validate state Valid
Credit 44.50
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.03 MB
Peak swap size 32.91 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_MID_3000-conf_782.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_MID_3000-conf_782_0_r488947355_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_MID_3000-conf_782_0_r488947355_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.791519
     * GNaL_b in INaL: 0.005653
     * Gto_b in Ito: 0.086683
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031959
     * GKs_b in IKs: 0.001904
     * GK1_b in IK1: 0.163809
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.567848
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036907
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 6456292, states[0] = -94.178136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14612727, states[0] = -94.252069, states[40]= 0.000001
Saving checkpoint... 
Iteration: 25482361, states[0] = -94.234643, states[40]= 0.000001
Saving checkpoint... 
Iteration: 36379010, states[0] = -94.008626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42547852, states[0] = -94.231112, states[40]= 0.000001
Saving checkpoint... 
Iteration: 53259120, states[0] = -94.281359, states[40]= 0.000001
Saving checkpoint... 
Iteration: 64486866, states[0] = -94.268221, states[40]= 0.000001
Saving checkpoint... 
Iteration: 75188283, states[0] = -23.752214, states[40]= 0.006206
Saving checkpoint... 
Iteration: 86636596, states[0] = -94.293647, states[40]= 0.000001
Saving checkpoint... 
Iteration: 97192304, states[0] = -94.295553, states[40]= 0.000001
Saving checkpoint... 
Iteration: 107100235, states[0] = -94.292631, states[40]= 0.000001
Saving checkpoint... 
Iteration: 117634040, states[0] = -94.302409, states[40]= 0.000001
Saving checkpoint... 
Iteration: 127771086, states[0] = -92.979479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138739357, states[0] = -94.315878, states[40]= 0.000001
Saving checkpoint... 
Iteration: 149661241, states[0] = -94.306391, states[40]= 0.000001
Saving checkpoint... 
Iteration: 160432297, states[0] = -94.297314, states[40]= 0.000001
Saving checkpoint... 
Iteration: 171456384, states[0] = -94.219325, states[40]= 0.000001
Saving checkpoint... 
Iteration: 182543456, states[0] = -94.312671, states[40]= 0.000001
Saving checkpoint... 
Iteration: 193174312, states[0] = -94.307507, states[40]= 0.000001
Saving checkpoint... 
Iteration: 203801949, states[0] = -94.302723, states[40]= 0.000001
Saving checkpoint... 
Iteration: 214243579, states[0] = -94.304889, states[40]= 0.000001
Saving checkpoint... 
Iteration: 225284635, states[0] = -93.713146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236938088, states[0] = -94.298036, states[40]= 0.000001
Saving checkpoint... 
Iteration: 247022143, states[0] = -94.313530, states[40]= 0.000001
Saving checkpoint... 
Iteration: 258126030, states[0] = 4.233644, states[40]= 0.000225
Saving checkpoint... 
Iteration: 268580457, states[0] = 21.976899, states[40]= 0.000003
Saving checkpoint... 
Iteration: 275953622, states[0] = -94.297040, states[40]= 0.000001
Saving checkpoint... 
Iteration: 286231291, states[0] = -94.304533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 296174274, states[0] = -94.313140, states[40]= 0.000001
Saving checkpoint... 
Iteration: 306852594, states[0] = -94.318095, states[40]= 0.000001
Saving checkpoint... 
Iteration: 317480847, states[0] = -94.314032, states[40]= 0.000001
Saving checkpoint... 
Iteration: 327778020, states[0] = -94.318053, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_MID_3000-conf_782.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_MID_3000-conf_782_0_r488947355_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_MID_3000-conf_782_0_r488947355_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.791519
     * GNaL_b in INaL: 0.005653
     * Gto_b in Ito: 0.086683
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031959
     * GKs_b in IKs: 0.001904
     * GK1_b in IK1: 0.163809
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.567848
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036907
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 327778020
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.318053 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 337811955, states[0] = -93.864204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348085209, states[0] = 20.220468, states[40]= 0.000005
Saving checkpoint... 
Iteration: 358538783, states[0] = 33.267516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368609177, states[0] = -94.307917, states[40]= 0.000001
Saving checkpoint... 
Iteration: 379310324, states[0] = -94.299918, states[40]= 0.000001
Saving checkpoint... 
Iteration: 388989986, states[0] = -94.247798, states[40]= 0.000001
Saving checkpoint... 
Iteration: 399154531, states[0] = -9.751406, states[40]= 0.000832
Saving checkpoint... 
Iteration: 409541360, states[0] = 32.959171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420123009, states[0] = 5.460936, states[40]= 0.000179
Saving checkpoint... 
Iteration: 430159183, states[0] = -94.304718, states[40]= 0.000001
Saving checkpoint... 
Iteration: 440659907, states[0] = -94.304488, states[40]= 0.000001
Saving checkpoint... 
Iteration: 451051554, states[0] = -94.308714, states[40]= 0.000001
Saving checkpoint... 
Iteration: 461044986, states[0] = -94.278694, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470621814, states[0] = -94.305463, states[40]= 0.000001
Saving checkpoint... 
Iteration: 481163744, states[0] = -94.303561, states[40]= 0.000001
Saving checkpoint... 
Iteration: 491615655, states[0] = -94.305313, states[40]= 0.000001
Saving checkpoint... 
Iteration: 502264402, states[0] = -94.299252, states[40]= 0.000001
Saving checkpoint... 
Iteration: 512226629, states[0] = -94.313057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 522952374, states[0] = -94.311202, states[40]= 0.000001
Saving checkpoint... 
Iteration: 533178514, states[0] = -94.309132, states[40]= 0.000001
Saving checkpoint... 
Iteration: 543641987, states[0] = -94.304244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 554078272, states[0] = -94.289410, states[40]= 0.000001
Saving checkpoint... 
Iteration: 565103410, states[0] = -94.304413, states[40]= 0.000001
Saving checkpoint... 
Iteration: 575402221, states[0] = -94.311839, states[40]= 0.000001
Saving checkpoint... 
Iteration: 585697949, states[0] = -94.309862, states[40]= 0.000001
Saving checkpoint... 
Iteration: 596647078, states[0] = -94.302031, states[40]= 0.000001
Saving checkpoint... 
Iteration: 606809158, states[0] = -94.312898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 616788626, states[0] = -93.732452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626808240, states[0] = -94.295275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 637013934, states[0] = -94.306687, states[40]= 0.000001
Saving checkpoint... 
Iteration: 647920463, states[0] = -94.291092, states[40]= 0.000001
Saving checkpoint... 
Iteration: 659162334, states[0] = -94.304907, states[40]= 0.000001
Saving checkpoint... 
Iteration: 669216797, states[0] = -41.420494, states[40]= 0.002152
Saving checkpoint... 
Iteration: 679459892, states[0] = -94.289273, states[40]= 0.000001
Saving checkpoint... 
Iteration: 689857624, states[0] = -94.292351, states[40]= 0.000001
Saving checkpoint... 
Iteration: 700395977, states[0] = -94.290874, states[40]= 0.000001
Saving checkpoint... 
Iteration: 710213712, states[0] = -94.308574, states[40]= 0.000001
Saving checkpoint... 
Iteration: 721103151, states[0] = -94.301449, states[40]= 0.000001
Saving checkpoint... 
Iteration: 730907674, states[0] = -94.144260, states[40]= 0.000001
Saving checkpoint... 
Iteration: 741624703, states[0] = -94.297434, states[40]= 0.000001
Saving checkpoint... 
Iteration: 752039094, states[0] = -94.270451, states[40]= 0.000001
Saving checkpoint... 
Iteration: 763221915, states[0] = -94.295891, states[40]= 0.000001
Saving checkpoint... 
Iteration: 773200854, states[0] = -94.306515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 784002136, states[0] = -94.304358, states[40]= 0.000001
Saving checkpoint... 
Iteration: 794252698, states[0] = -94.308685, states[40]= 0.000001
Saving checkpoint... 
Iteration: 805150621, states[0] = -94.297919, states[40]= 0.000001
Saving checkpoint... 
Iteration: 815255739, states[0] = -94.308366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 824937610, states[0] = -94.287185, states[40]= 0.000001
Saving checkpoint... 
Iteration: 835942655, states[0] = -94.193334, states[40]= 0.000001
Saving checkpoint... 
Iteration: 846507283, states[0] = -94.251143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 857536258, states[0] = -94.301592, states[40]= 0.000001
Saving checkpoint... 
Iteration: 867922716, states[0] = -94.305644, states[40]= 0.000001
Saving checkpoint... 
Iteration: 878642580, states[0] = -94.296841, states[40]= 0.000001
Saving checkpoint... 
Iteration: 889461469, states[0] = -94.285223, states[40]= 0.000001
Saving checkpoint... 
Iteration: 899483534, states[0] = -94.302876, states[40]= 0.000001
Saving checkpoint... 
Iteration: 910056467, states[0] = -94.299770, states[40]= 0.000001
Saving checkpoint... 
Iteration: 920833517, states[0] = -94.288780, states[40]= 0.000001
Saving checkpoint... 
Iteration: 930920188, states[0] = -94.304521, states[40]= 0.000001
Saving checkpoint... 
Iteration: 941351114, states[0] = -94.306083, states[40]= 0.000001
Saving checkpoint... 
Iteration: 951536297, states[0] = -94.265316, states[40]= 0.000001
Saving checkpoint... 
Iteration: 962752392, states[0] = -94.290923, states[40]= 0.000001
Saving checkpoint... 
Iteration: 973480611, states[0] = -94.283048, states[40]= 0.000001
Saving checkpoint... 
Iteration: 984069711, states[0] = 25.758606, states[40]= 0.000001
Saving checkpoint... 
Iteration: 994053562, states[0] = -94.298284, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1004845035, states[0] = -94.286777, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1014945613, states[0] = -94.302066, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1025594706, states[0] = -94.295995, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1035890526, states[0] = -94.303395, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1046062977, states[0] = -94.274792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1055564401, states[0] = -94.296666, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1065482822, states[0] = -94.229203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1075930079, states[0] = -94.172396, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1086253114, states[0] = -73.278019, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1095663171, states[0] = -94.296691, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1106102751, states[0] = -94.285700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1115397662, states[0] = -94.301682, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1126580651, states[0] = 21.909464, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1136364151, states[0] = -94.302113, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1146547572, states[0] = -94.266723, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1157136083, states[0] = -94.291575, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1167988383, states[0] = -94.297569, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1178641556, states[0] = -94.291158, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1189003411, states[0] = -94.296582, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1199438300, states[0] = -94.298803, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1209772307, states[0] = -94.301189, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1220161508, states[0] = -94.294110, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1231164660, states[0] = -94.289223, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1241321118, states[0] = -94.300752, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1251787804, states[0] = -94.300573, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1262200895, states[0] = -94.297200, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1272445378, states[0] = -94.188224, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1282742716, states[0] = -61.674703, states[40]= 0.000129
Saving checkpoint... 
Iteration: 1292708330, states[0] = -94.286327, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1303121745, states[0] = -94.289600, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1314013843, states[0] = 30.949588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321245430, states[0] = -94.284354, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1331873682, states[0] = -94.279572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1341856911, states[0] = -94.298349, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1352616395, states[0] = -94.288876, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1363305943, states[0] = -94.281317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1374197336, states[0] = -29.962509, states[40]= 0.006011
Saving checkpoint... 
Iteration: 1384492836, states[0] = -94.274852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1395044399, states[0] = 32.506074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404978185, states[0] = -94.293447, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1415549332, states[0] = -94.290425, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1426285867, states[0] = -94.280842, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1436963982, states[0] = -94.274702, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1446833653, states[0] = -94.296712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1457152216, states[0] = -94.288358, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1467762945, states[0] = -94.296104, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1478723079, states[0] = -94.282204, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1489009128, states[0] = -94.290643, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1495863433, states[0] = -94.031747, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.148397
 - CaMKt in component CaMK (millimolar): 0.004516
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 7.983383
 - nass in component intracellular_ions (millimolar): 7.983550
 - ki in component intracellular_ions (millimolar): 143.722578
 - kss in component intracellular_ions (millimolar): 143.722559
 - cansr in component intracellular_ions (millimolar): 1.945475
 - cajsr in component intracellular_ions (millimolar): 1.947874
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003904
 - hf in component INa (dimensionless): 0.866299
 - hs in component INa (dimensionless): 0.866300
 - j in component INa (dimensionless): 0.866307
 - hsp in component INa (dimensionless): 0.700551
 - jp in component INa (dimensionless): 0.866311
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708924
 - hLp in component INaL (dimensionless): 0.510737
 - a in component Ito (dimensionless): 0.000656
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.964411
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.981471
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.985843
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004995
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.033709
 - xs1 in component IKs (dimensionless): 0.092800
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997528
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
01:58:02 (60931): called boinc_finish(0)

</stderr_txt>
]]>


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