𝕏

Task 55857458

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_EPI_2000-conf_982_0
Workunit 26525368
Created 3 Jul 2024, 5:15:36 UTC
Sent 3 Jul 2024, 8:13:09 UTC
Report deadline 6 Jul 2024, 8:13:09 UTC
Received 5 Jul 2024, 6:21:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 50 min 9 sec
CPU time 1 hours 40 min 50 sec
Validate state Valid
Credit 43.86
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.92 MB
Peak swap size 32.79 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_EPI_2000-conf_982.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_EPI_2000-conf_982_0_r2021929160_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_EPI_2000-conf_982_0_r2021929160_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.864285
     * GNaL_b in INaL: 0.005757
     * Gto_b in Ito: 0.083703
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031997
     * GKs_b in IKs: 0.001973
     * GK1_b in IK1: 0.159420
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.154589
     * GKb_b in IKb: 0.003817
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029337
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7425383, states[0] = -94.391026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18443619, states[0] = -94.337616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29110413, states[0] = -5.372327, states[40]= 0.000178
Saving checkpoint... 
Iteration: 39593001, states[0] = -94.347093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50515726, states[0] = -94.344256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61554981, states[0] = -94.356340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72184465, states[0] = -93.176421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82973599, states[0] = -94.353575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94003464, states[0] = 13.698418, states[40]= 1.362988
Saving checkpoint... 
Iteration: 105220064, states[0] = -93.815444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116512590, states[0] = -94.371456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127370247, states[0] = -94.297613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137928196, states[0] = -94.368261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148394639, states[0] = -94.322689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159150188, states[0] = -55.262414, states[40]= 0.000068
Saving checkpoint... 
Iteration: 170582804, states[0] = -94.382898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181645723, states[0] = -94.384041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191852552, states[0] = -94.374305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201998837, states[0] = -94.364984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208457946, states[0] = -94.359888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219709340, states[0] = -94.381868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230939842, states[0] = -94.368126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242070310, states[0] = 16.671850, states[40]= 0.000007
Saving checkpoint... 
Iteration: 253053028, states[0] = 22.692717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263626873, states[0] = -94.382629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274642530, states[0] = -94.382311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285967658, states[0] = -94.365000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296986431, states[0] = -94.363535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308361704, states[0] = -94.287264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320382484, states[0] = -94.309496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331644298, states[0] = -94.380727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343248749, states[0] = -93.987537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350791676, states[0] = -94.374206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359458841, states[0] = -94.356360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366370958, states[0] = -94.296365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373697670, states[0] = -94.378247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384608135, states[0] = -94.379038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395847731, states[0] = -94.369512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401781291, states[0] = -94.373372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412324804, states[0] = -94.227411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422569016, states[0] = -94.376227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433340931, states[0] = -94.254807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444411915, states[0] = -94.329771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455245135, states[0] = -93.966048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465941505, states[0] = -94.361574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475998137, states[0] = -94.357760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486515830, states[0] = -94.368092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497023066, states[0] = 24.623276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507860226, states[0] = -94.365551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518497183, states[0] = -94.363400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529067660, states[0] = 17.777264, states[40]= 0.000005
Saving checkpoint... 
Iteration: 540096978, states[0] = 2.066435, states[40]= 0.000186
Saving checkpoint... 
Iteration: 550991023, states[0] = -94.356070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562036841, states[0] = 25.330591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572686023, states[0] = -94.373033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583842227, states[0] = -94.364542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593899580, states[0] = -94.360629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604531312, states[0] = -94.367216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615022456, states[0] = 24.521948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625467103, states[0] = -94.351829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632573936, states[0] = -94.370626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643264248, states[0] = -94.048423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653358465, states[0] = -94.273422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664233715, states[0] = -93.896640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674897272, states[0] = -94.358472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685455363, states[0] = -94.345785, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_EPI_2000-conf_982.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_EPI_2000-conf_982_0_r2021929160_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_EPI_2000-conf_982_0_r2021929160_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.864285
     * GNaL_b in INaL: 0.005757
     * Gto_b in Ito: 0.083703
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031997
     * GKs_b in IKs: 0.001973
     * GK1_b in IK1: 0.159420
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.154589
     * GKb_b in IKb: 0.003817
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029337
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 685455363
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.345785 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 695556808, states[0] = -94.367541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706311416, states[0] = -94.191209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716798572, states[0] = -94.363450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727957866, states[0] = -94.353129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739087629, states[0] = 8.001638, states[40]= 0.000070
Saving checkpoint... 
Iteration: 749788967, states[0] = -94.363088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760315459, states[0] = -94.198553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770938949, states[0] = -94.353103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781123274, states[0] = -23.904481, states[40]= 0.000423
Saving checkpoint... 
Iteration: 791981867, states[0] = -94.349819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801969763, states[0] = -94.350294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812769697, states[0] = -94.362401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822790662, states[0] = -94.360914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832895542, states[0] = -94.354105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843266556, states[0] = -94.051888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853706150, states[0] = -94.364350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863980173, states[0] = -94.347888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874222060, states[0] = -93.816315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884658573, states[0] = -94.364897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895183689, states[0] = -93.242357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905690482, states[0] = -94.363458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916430296, states[0] = -94.327537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926898799, states[0] = -94.351248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937638223, states[0] = -94.363648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947631089, states[0] = -94.363380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958123915, states[0] = -24.609109, states[40]= 0.000440
Saving checkpoint... 
Iteration: 968704871, states[0] = -94.361156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978596535, states[0] = -94.361927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989666661, states[0] = -94.361780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000312653, states[0] = -94.185579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011067225, states[0] = 17.958343, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1021603353, states[0] = -94.360915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031345766, states[0] = -94.245175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041456250, states[0] = -94.336059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051417537, states[0] = -94.316240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062089612, states[0] = 6.841158, states[40]= 0.000087
Saving checkpoint... 
Iteration: 1071795276, states[0] = -94.353603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082963696, states[0] = -94.342715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092717396, states[0] = -94.357126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103037805, states[0] = 25.276029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113534029, states[0] = -94.353185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123875686, states[0] = -94.347139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134375941, states[0] = -94.279866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143989252, states[0] = -94.339398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154662764, states[0] = -94.357191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165255795, states[0] = -93.997078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176008961, states[0] = 19.961958, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1186740546, states[0] = -94.353366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197813671, states[0] = -94.348927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208293231, states[0] = -94.130879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218425062, states[0] = -94.316048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228710770, states[0] = -94.353553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239327907, states[0] = -94.209641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249934950, states[0] = -94.339789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260239536, states[0] = -93.912713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270255288, states[0] = -93.991735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281124769, states[0] = -25.544687, states[40]= 0.000462
Saving checkpoint... 
Iteration: 1291897439, states[0] = -94.341009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302288559, states[0] = -94.114603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313341184, states[0] = -94.230153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323970108, states[0] = -94.335497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334118945, states[0] = -19.058655, states[40]= 0.000332
Saving checkpoint... 
Iteration: 1345181207, states[0] = -92.875942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355394069, states[0] = -94.290506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365907663, states[0] = -94.338257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376087449, states[0] = 8.115123, states[40]= 0.000068
Saving checkpoint... 
Iteration: 1387203239, states[0] = -93.659841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397950833, states[0] = -94.334613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408693825, states[0] = -94.349127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419208991, states[0] = -93.705034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429676877, states[0] = -94.349069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440623621, states[0] = -94.349403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450920369, states[0] = -94.335042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459996551, states[0] = -94.330007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470027085, states[0] = 25.148353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479966006, states[0] = -94.331330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491030049, states[0] = 25.362654, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.204599
 - CaMKt in component CaMK (millimolar): 0.007256
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.396502
 - nass in component intracellular_ions (millimolar): 7.396647
 - ki in component intracellular_ions (millimolar): 144.117066
 - kss in component intracellular_ions (millimolar): 144.117043
 - cansr in component intracellular_ions (millimolar): 2.595508
 - cajsr in component intracellular_ions (millimolar): 2.596434
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003882
 - hf in component INa (dimensionless): 0.867365
 - hs in component INa (dimensionless): 0.867368
 - j in component INa (dimensionless): 0.867382
 - hsp in component INa (dimensionless): 0.702493
 - jp in component INa (dimensionless): 0.867390
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.710388
 - hLp in component INaL (dimensionless): 0.502196
 - a in component Ito (dimensionless): 0.000653
 - iF in component Ito (dimensionless): 0.999853
 - iS in component Ito (dimensionless): 0.999853
 - ap in component Ito (dimensionless): 0.000333
 - iFp in component Ito (dimensionless): 0.999853
 - iSp in component Ito (dimensionless): 0.999853
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.974675
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005377
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.092496
 - xs1 in component IKs (dimensionless): 0.127985
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997514
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:20:52 (60927): called boinc_finish(0)

</stderr_txt>
]]>


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