𝕏

Task 55857413

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_EPI_1000-conf_582_1
Workunit 26525345
Created 3 Jul 2024, 5:15:36 UTC
Sent 3 Jul 2024, 8:13:09 UTC
Report deadline 6 Jul 2024, 8:13:09 UTC
Received 5 Jul 2024, 7:28:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 53 min 53 sec
CPU time 1 hours 41 min 40 sec
Validate state Valid
Credit 45.70
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.05 MB
Peak swap size 32.91 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_EPI_1000-conf_582.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_EPI_1000-conf_582_1_r267749072_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_EPI_1000-conf_582_1_r267749072_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 107.047976
     * GNaL_b in INaL: 0.006129
     * Gto_b in Ito: 0.082867
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031784
     * GKs_b in IKs: 0.001967
     * GK1_b in IK1: 0.162913
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.748568
     * GKb_b in IKb: 0.003787
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029009
     * celltype in environment: 1.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7118804, states[0] = -17.903039, states[40]= 0.000050
Saving checkpoint... 
Iteration: 16812719, states[0] = -94.463243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26923319, states[0] = -94.552211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37231306, states[0] = -94.219825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47945801, states[0] = -94.589357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58456872, states[0] = -94.607068, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_EPI_1000-conf_582.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_EPI_1000-conf_582_1_r267749072_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_EPI_1000-conf_582_1_r267749072_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 107.047976
     * GNaL_b in INaL: 0.006129
     * Gto_b in Ito: 0.082867
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031784
     * GKs_b in IKs: 0.001967
     * GK1_b in IK1: 0.162913
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.748568
     * GKb_b in IKb: 0.003787
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029009
     * celltype in environment: 1.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 58456872
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.607068 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 68006651, states[0] = 17.913923, states[40]= 0.000003
Saving checkpoint... 
Iteration: 78054097, states[0] = 19.593720, states[40]= 0.000006
Saving checkpoint... 
Iteration: 87483099, states[0] = -94.637305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97742343, states[0] = -94.337267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107352086, states[0] = -94.590335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117328355, states[0] = -94.565541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127273148, states[0] = -94.455957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137590838, states[0] = -0.803408, states[40]= 0.001568
Saving checkpoint... 
Iteration: 147363053, states[0] = -94.604652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157694335, states[0] = -94.035889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167387366, states[0] = -94.621239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177099014, states[0] = -9.323740, states[40]= 0.002082
Saving checkpoint... 
Iteration: 186289589, states[0] = -94.498278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195649073, states[0] = -72.091629, states[40]= 0.000037
Saving checkpoint... 
Iteration: 205375707, states[0] = -94.611799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215693125, states[0] = -94.021923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225867377, states[0] = -94.604272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236256592, states[0] = -94.398457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246159453, states[0] = -89.376767, states[40]= 0.000002
Saving checkpoint... 
Iteration: 256617427, states[0] = -31.503609, states[40]= 0.002651
Saving checkpoint... 
Iteration: 266232459, states[0] = -94.290434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276436565, states[0] = -94.633610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286895021, states[0] = -94.616983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297317912, states[0] = -94.543390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306690920, states[0] = -93.994353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317090118, states[0] = -0.312407, states[40]= 0.001527
Saving checkpoint... 
Iteration: 327356481, states[0] = -94.586963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337785486, states[0] = -94.476779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347322894, states[0] = -94.546686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357240201, states[0] = -94.320780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367118392, states[0] = -32.648702, states[40]= 0.002603
Saving checkpoint... 
Iteration: 376788685, states[0] = -94.481151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386999456, states[0] = -94.633892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396676606, states[0] = -93.828979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406410995, states[0] = -94.614560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416601660, states[0] = -12.522468, states[40]= 0.001935
Saving checkpoint... 
Iteration: 426650329, states[0] = -74.128797, states[40]= 0.000028
Saving checkpoint... 
Iteration: 436933285, states[0] = -94.619614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446639150, states[0] = -58.433855, states[40]= 0.000249
Saving checkpoint... 
Iteration: 455818070, states[0] = -94.530593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465837558, states[0] = -94.556076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475989732, states[0] = -94.625967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486517208, states[0] = 22.466717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497520422, states[0] = 23.020926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507367070, states[0] = -94.581051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517330892, states[0] = -94.543616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526949843, states[0] = -94.616231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536949275, states[0] = -94.615310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546593263, states[0] = -3.164012, states[40]= 0.001882
Saving checkpoint... 
Iteration: 556679564, states[0] = -93.855998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567253206, states[0] = -94.358303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577485458, states[0] = -94.617268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587756668, states[0] = -94.369584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597490800, states[0] = -94.616084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608136422, states[0] = -54.976902, states[40]= 0.000388
Saving checkpoint... 
Iteration: 618008346, states[0] = 19.346612, states[40]= 0.000005
Saving checkpoint... 
Iteration: 627517302, states[0] = 22.487878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637542774, states[0] = 22.197802, states[40]= 0.000001
Saving checkpoint... 
Iteration: 647101768, states[0] = -12.633515, states[40]= 0.001929
Saving checkpoint... 
Iteration: 656060144, states[0] = 17.025512, states[40]= 0.000024
Saving checkpoint... 
Iteration: 666162167, states[0] = -91.676314, states[40]= 0.000001
Saving checkpoint... 
Iteration: 676172853, states[0] = -93.724041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686051026, states[0] = 20.175525, states[40]= 0.000004
Saving checkpoint... 
Iteration: 695587599, states[0] = 1.768327, states[40]= 0.001206
Saving checkpoint... 
Iteration: 705767463, states[0] = -94.396437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715108706, states[0] = -21.092006, states[40]= 0.001880
Saving checkpoint... 
Iteration: 725333821, states[0] = -94.530226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736117180, states[0] = -31.172459, states[40]= 0.002637
Saving checkpoint... 
Iteration: 746279789, states[0] = -94.428598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756485756, states[0] = -94.602668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766914321, states[0] = -94.586276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776555166, states[0] = 18.864305, states[40]= 0.000010
Saving checkpoint... 
Iteration: 786008586, states[0] = 19.495923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796058875, states[0] = 17.524179, states[40]= 0.000019
Saving checkpoint... 
Iteration: 804917788, states[0] = -94.584457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814219722, states[0] = -94.172047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823730750, states[0] = -94.234857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833125113, states[0] = -40.753446, states[40]= 0.001679
Saving checkpoint... 
Iteration: 843064457, states[0] = 15.222276, states[40]= 0.000050
Saving checkpoint... 
Iteration: 852681337, states[0] = -93.851559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862931967, states[0] = -94.584285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872978777, states[0] = -94.592392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882920470, states[0] = -94.578999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893486549, states[0] = -94.591476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903918857, states[0] = -94.576714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914478310, states[0] = -94.588935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925035497, states[0] = 23.276381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934635372, states[0] = -53.623297, states[40]= 0.000455
Saving checkpoint... 
Iteration: 945317866, states[0] = -94.489898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955691225, states[0] = -93.942033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965949511, states[0] = -94.580175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975849623, states[0] = -94.527140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985428741, states[0] = -94.573279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995531523, states[0] = 23.553704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005958917, states[0] = -94.578685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013134236, states[0] = -52.185545, states[40]= 0.000539
Saving checkpoint... 
Iteration: 1023346654, states[0] = -94.520260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032789722, states[0] = -94.429356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043626913, states[0] = -42.968779, states[40]= 0.001392
Saving checkpoint... 
Iteration: 1053585980, states[0] = 3.017894, states[40]= 0.001006
Saving checkpoint... 
Iteration: 1063376316, states[0] = -94.542143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073961584, states[0] = -94.573602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084807014, states[0] = -94.460260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095032193, states[0] = 23.526065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104785359, states[0] = -94.413024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114623545, states[0] = -38.801692, states[40]= 0.001925
Saving checkpoint... 
Iteration: 1124412763, states[0] = -94.556334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134386285, states[0] = -94.542622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144165356, states[0] = -92.928684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1153930706, states[0] = -94.560057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163707351, states[0] = -94.058302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173489043, states[0] = -94.568758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179841726, states[0] = -94.502047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187079123, states[0] = 7.616269, states[40]= 0.000440
Saving checkpoint... 
Iteration: 1194301369, states[0] = -94.440625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205867640, states[0] = -94.524085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212921504, states[0] = -94.552300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220125155, states[0] = -40.770129, states[40]= 0.001667
Saving checkpoint... 
Iteration: 1231787739, states[0] = -94.408213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243250474, states[0] = -94.291286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250911226, states[0] = -94.545330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263064396, states[0] = 15.263940, states[40]= 0.000049
Saving checkpoint... 
Iteration: 1273772679, states[0] = -94.365100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285309896, states[0] = -94.448787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296909826, states[0] = -94.540994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308718007, states[0] = -94.119632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320367794, states[0] = -94.514785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333031212, states[0] = 23.573988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343942896, states[0] = -94.547770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355343634, states[0] = -94.489759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366390594, states[0] = -94.526062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378710397, states[0] = -94.062365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389715844, states[0] = -94.098797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401356517, states[0] = -94.498732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411481037, states[0] = -94.548525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422130425, states[0] = -47.340156, states[40]= 0.000912
Saving checkpoint... 
Iteration: 1433209941, states[0] = -94.054480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444748704, states[0] = -94.267309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456476295, states[0] = -94.544306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467271293, states[0] = -94.344962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478300997, states[0] = -94.416443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489820547, states[0] = -94.449091, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.418653
 - CaMKt in component CaMK (millimolar): 0.028448
 - cass in component intracellular_ions (millimolar): 0.000108
 - nai in component intracellular_ions (millimolar): 7.926874
 - nass in component intracellular_ions (millimolar): 7.927051
 - ki in component intracellular_ions (millimolar): 143.022677
 - kss in component intracellular_ions (millimolar): 143.022638
 - cansr in component intracellular_ions (millimolar): 3.299581
 - cajsr in component intracellular_ions (millimolar): 3.279364
 - cai in component intracellular_ions (millimolar): 0.000113
 - m in component INa (dimensionless): 0.003799
 - hf in component INa (dimensionless): 0.871361
 - hs in component INa (dimensionless): 0.871358
 - j in component INa (dimensionless): 0.871335
 - hsp in component INa (dimensionless): 0.709762
 - jp in component INa (dimensionless): 0.871314
 - mL in component INaL (dimensionless): 0.000054
 - hL in component INaL (dimensionless): 0.696764
 - hLp in component INaL (dimensionless): 0.437019
 - a in component Ito (dimensionless): 0.000644
 - iF in component Ito (dimensionless): 0.999858
 - iS in component Ito (dimensionless): 0.999858
 - ap in component Ito (dimensionless): 0.000328
 - iFp in component Ito (dimensionless): 0.999858
 - iSp in component Ito (dimensionless): 0.999858
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.916367
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999863
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.006922
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331190
 - xs1 in component IKs (dimensionless): 0.272593
 - xs2 in component IKs (dimensionless): 0.000093
 - xk1 in component IK1 (dimensionless): 0.997461
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:28:35 (60936): called boinc_finish(0)

</stderr_txt>
]]>


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