𝕏

Task 55857233

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-Coppini_1000-conf_182_1
Workunit 26525255
Created 3 Jul 2024, 5:15:31 UTC
Sent 3 Jul 2024, 8:13:09 UTC
Report deadline 6 Jul 2024, 8:13:09 UTC
Received 5 Jul 2024, 6:21:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 52 min 38 sec
CPU time 1 hours 41 min 59 sec
Validate state Valid
Credit 44.17
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.22 MB
Peak swap size 32.91 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Coppini_1000-conf_182.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Coppini_1000-conf_182_1_r858395056_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Coppini_1000-conf_182_1_r858395056_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.910646
     * GNaL_b in INaL: 0.006128
     * Gto_b in Ito: 0.081650
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032355
     * GKs_b in IKs: 0.001961
     * GK1_b in IK1: 0.166224
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.127140
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031469
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 7228576, states[0] = -94.819277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18536244, states[0] = 22.321547, states[40]= 0.002399
Saving checkpoint... 
Iteration: 29063357, states[0] = 11.632252, states[40]= 0.004051
Saving checkpoint... 
Iteration: 35119969, states[0] = -32.764464, states[40]= 0.000777
Saving checkpoint... 
Iteration: 45100505, states[0] = -13.508835, states[40]= 0.001978
Saving checkpoint... 
Iteration: 56128761, states[0] = -41.060418, states[40]= 0.000315
Saving checkpoint... 
Iteration: 66520313, states[0] = 27.159633, states[40]= 0.002706
Saving checkpoint... 
Iteration: 76715776, states[0] = -94.626085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87143842, states[0] = -56.883107, states[40]= 0.000031
Saving checkpoint... 
Iteration: 98935029, states[0] = -94.946120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109640181, states[0] = -52.798352, states[40]= 0.000060
Saving checkpoint... 
Iteration: 120335245, states[0] = -94.879718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130781242, states[0] = -94.802828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141660679, states[0] = -78.984789, states[40]= 0.000001
Saving checkpoint... 
Iteration: 152280453, states[0] = -94.801003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162527492, states[0] = 25.477636, states[40]= 0.001669
Saving checkpoint... 
Iteration: 172920629, states[0] = -94.938685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183536925, states[0] = 22.429920, states[40]= 0.002010
Saving checkpoint... 
Iteration: 194336221, states[0] = -94.879791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205006421, states[0] = 29.370189, states[40]= 0.160253
Saving checkpoint... 
Iteration: 216013922, states[0] = 27.937809, states[40]= 0.013665
Saving checkpoint... 
Iteration: 226392830, states[0] = -94.924235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237300912, states[0] = -94.835055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247806390, states[0] = -94.843055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257910280, states[0] = -94.933412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265015654, states[0] = 27.823304, states[40]= 0.008121
Saving checkpoint... 
Iteration: 275461046, states[0] = -94.952727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285287405, states[0] = -94.812850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296631410, states[0] = -43.439260, states[40]= 0.000232
Saving checkpoint... 
Iteration: 307139575, states[0] = -52.071279, states[40]= 0.000067
Saving checkpoint... 
Iteration: 316451069, states[0] = -94.949499, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Coppini_1000-conf_182.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Coppini_1000-conf_182_1_r858395056_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Coppini_1000-conf_182_1_r858395056_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.910646
     * GNaL_b in INaL: 0.006128
     * Gto_b in Ito: 0.081650
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032355
     * GKs_b in IKs: 0.001961
     * GK1_b in IK1: 0.166224
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.127140
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031469
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 316451069
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.949499 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 326601649, states[0] = -14.284977, states[40]= 0.001856
Saving checkpoint... 
Iteration: 336786480, states[0] = -94.811016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346847374, states[0] = -94.890071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357454297, states[0] = -94.950364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368337290, states[0] = -94.880137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378799246, states[0] = -94.831936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388866261, states[0] = -94.905809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399522454, states[0] = 26.761109, states[40]= 0.002050
Saving checkpoint... 
Iteration: 409663018, states[0] = -82.896471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420085400, states[0] = -0.201207, states[40]= 0.004561
Saving checkpoint... 
Iteration: 430639545, states[0] = -52.038012, states[40]= 0.000067
Saving checkpoint... 
Iteration: 440604361, states[0] = -16.982548, states[40]= 0.001509
Saving checkpoint... 
Iteration: 450050605, states[0] = 17.283954, states[40]= 0.002969
Saving checkpoint... 
Iteration: 459617179, states[0] = -29.439131, states[40]= 0.001013
Saving checkpoint... 
Iteration: 469966952, states[0] = -94.953635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479490231, states[0] = -94.959267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489754181, states[0] = -94.741829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500428080, states[0] = -94.940415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510330657, states[0] = -94.872517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520977680, states[0] = -94.956222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531032918, states[0] = 23.802071, states[40]= 0.001809
Saving checkpoint... 
Iteration: 541431730, states[0] = -94.941718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551386211, states[0] = -94.918951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561848472, states[0] = -94.890244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571825052, states[0] = -94.865911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582539390, states[0] = 21.550104, states[40]= 0.002156
Saving checkpoint... 
Iteration: 592755061, states[0] = -94.743636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603002195, states[0] = 43.534207, states[40]= 0.459629
Saving checkpoint... 
Iteration: 613480462, states[0] = -94.956536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623599611, states[0] = -12.270036, states[40]= 0.002210
Saving checkpoint... 
Iteration: 634353157, states[0] = -94.894152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645029475, states[0] = 24.896234, states[40]= 0.001692
Saving checkpoint... 
Iteration: 655386149, states[0] = -94.918508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665074697, states[0] = 6.301179, states[40]= 0.004638
Saving checkpoint... 
Iteration: 674808281, states[0] = -94.844042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685433304, states[0] = -94.941772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696181060, states[0] = -94.377438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706773808, states[0] = -94.785522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717679470, states[0] = -94.310213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728317325, states[0] = -94.855883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738257703, states[0] = -94.749575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748721995, states[0] = -94.643538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759044682, states[0] = 19.584310, states[40]= 0.002514
Saving checkpoint... 
Iteration: 769197232, states[0] = -94.543822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779708474, states[0] = -94.591923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790396745, states[0] = -94.924246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800500358, states[0] = -50.718658, states[40]= 0.000001
Saving checkpoint... 
Iteration: 811423141, states[0] = -94.937140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821456620, states[0] = -94.949279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831615198, states[0] = -27.536196, states[40]= 0.001107
Saving checkpoint... 
Iteration: 842413211, states[0] = -94.932539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853182193, states[0] = -94.409839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863355063, states[0] = -94.894908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873861907, states[0] = -94.900524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884200074, states[0] = -94.556114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894457064, states[0] = -94.949131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904444948, states[0] = -94.945173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914402564, states[0] = -94.926929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925124958, states[0] = -36.967224, states[40]= 0.000521
Saving checkpoint... 
Iteration: 934713675, states[0] = -94.611900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945613518, states[0] = -25.922385, states[40]= 0.001161
Saving checkpoint... 
Iteration: 955719391, states[0] = -94.633318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966228088, states[0] = -94.663741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976100123, states[0] = -12.772355, states[40]= 0.002115
Saving checkpoint... 
Iteration: 986551099, states[0] = 17.087980, states[40]= 0.003010
Saving checkpoint... 
Iteration: 996307712, states[0] = -94.841989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007023699, states[0] = 26.476878, states[40]= 0.001855
Saving checkpoint... 
Iteration: 1017366827, states[0] = -94.903794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027756516, states[0] = -94.745539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038670227, states[0] = -91.982527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049458949, states[0] = -94.949096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059442447, states[0] = -94.943700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068939546, states[0] = -94.942624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078691056, states[0] = -94.511408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088880621, states[0] = -94.913279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098966713, states[0] = -94.951128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108126807, states[0] = -38.790508, states[40]= 0.000421
Saving checkpoint... 
Iteration: 1118655373, states[0] = -70.741135, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1128723457, states[0] = -94.647215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139164428, states[0] = -85.213519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149203398, states[0] = -94.569417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159773876, states[0] = -94.783888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170055576, states[0] = 15.266659, states[40]= 0.003376
Saving checkpoint... 
Iteration: 1180119581, states[0] = -31.746455, states[40]= 0.000867
Saving checkpoint... 
Iteration: 1190831339, states[0] = -94.870615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200594470, states[0] = -7.399813, states[40]= 0.003284
Saving checkpoint... 
Iteration: 1211400055, states[0] = -94.924433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221269851, states[0] = -94.775288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231320885, states[0] = -94.858357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241070786, states[0] = 8.345484, states[40]= 0.004467
Saving checkpoint... 
Iteration: 1251281104, states[0] = -94.797645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261549441, states[0] = 17.745275, states[40]= 0.002877
Saving checkpoint... 
Iteration: 1272140391, states[0] = -52.950521, states[40]= 0.000058
Saving checkpoint... 
Iteration: 1282207806, states[0] = -94.587225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292172980, states[0] = -93.319830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299295537, states[0] = -94.822513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309472293, states[0] = -94.951802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320253167, states[0] = -94.735999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330234206, states[0] = -94.682154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340626474, states[0] = -38.459604, states[40]= 0.000438
Saving checkpoint... 
Iteration: 1351462332, states[0] = -94.948915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361386095, states[0] = -94.915730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371182184, states[0] = -94.407444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381935610, states[0] = -94.939950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393047513, states[0] = 18.498709, states[40]= 0.002726
Saving checkpoint... 
Iteration: 1403649410, states[0] = -63.093204, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1414351214, states[0] = -94.889403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424923583, states[0] = -94.934946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434899328, states[0] = -94.923169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445982779, states[0] = -94.953850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456571577, states[0] = 7.943519, states[40]= 0.004507
Saving checkpoint... 
Iteration: 1467366918, states[0] = -94.902113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473640117, states[0] = -52.652161, states[40]= 0.000061
Saving checkpoint... 
Iteration: 1480836905, states[0] = -94.875407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488124242, states[0] = -36.263827, states[40]= 0.000564
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.833175
 - CaMKt in component CaMK (millimolar): 0.012685
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.742715
 - nass in component intracellular_ions (millimolar): 6.742812
 - ki in component intracellular_ions (millimolar): 145.138817
 - kss in component intracellular_ions (millimolar): 145.138796
 - cansr in component intracellular_ions (millimolar): 1.667254
 - cajsr in component intracellular_ions (millimolar): 1.625717
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.003644
 - hf in component INa (dimensionless): 0.878804
 - hs in component INa (dimensionless): 0.878796
 - j in component INa (dimensionless): 0.878746
 - hsp in component INa (dimensionless): 0.723560
 - jp in component INa (dimensionless): 0.878712
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.705886
 - hLp in component INaL (dimensionless): 0.443855
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.612820
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.683912
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.916300
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999835
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003067
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.364868
 - xs1 in component IKs (dimensionless): 0.266498
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997355
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:00:43 (60932): called boinc_finish(0)

</stderr_txt>
]]>


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