𝕏

Task 55856742

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_MID_6000-conf_81_0
Workunit 26525010
Created 3 Jul 2024, 5:15:16 UTC
Sent 3 Jul 2024, 8:13:09 UTC
Report deadline 6 Jul 2024, 8:13:09 UTC
Received 5 Jul 2024, 6:21:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 52 min 19 sec
CPU time 1 hours 42 min 11 sec
Validate state Valid
Credit 44.18
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.91 MB
Peak swap size 32.79 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_MID_6000-conf_81.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_MID_6000-conf_81_0_r1363436009_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_MID_6000-conf_81_0_r1363436009_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.423789
     * GNaL_b in INaL: 0.006075
     * Gto_b in Ito: 0.085483
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031563
     * GKs_b in IKs: 0.001944
     * GK1_b in IK1: 0.164529
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.639203
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035719
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 3658129, states[0] = -94.258908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 11408589, states[0] = -94.213091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18934218, states[0] = -94.228635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30658680, states[0] = -94.197209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40587968, states[0] = -94.211529, states[40]= 0.000001
Saving checkpoint... 
Iteration: 47361385, states[0] = -94.207310, states[40]= 0.000001
Saving checkpoint... 
Iteration: 58672357, states[0] = -94.224353, states[40]= 0.000001
Saving checkpoint... 
Iteration: 69590369, states[0] = -94.218768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80814011, states[0] = -94.224457, states[40]= 0.000001
Saving checkpoint... 
Iteration: 91624920, states[0] = -94.239525, states[40]= 0.000001
Saving checkpoint... 
Iteration: 102264569, states[0] = -55.849554, states[40]= 0.000224
Saving checkpoint... 
Iteration: 112823555, states[0] = -94.240986, states[40]= 0.000001
Saving checkpoint... 
Iteration: 123637983, states[0] = -94.248362, states[40]= 0.000001
Saving checkpoint... 
Iteration: 134136795, states[0] = -94.240131, states[40]= 0.000001
Saving checkpoint... 
Iteration: 144784869, states[0] = -94.265972, states[40]= 0.000001
Saving checkpoint... 
Iteration: 155756787, states[0] = -94.238134, states[40]= 0.000001
Saving checkpoint... 
Iteration: 165453055, states[0] = -94.145193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176485474, states[0] = -94.240229, states[40]= 0.000001
Saving checkpoint... 
Iteration: 187135970, states[0] = -94.262805, states[40]= 0.000001
Saving checkpoint... 
Iteration: 198069404, states[0] = 27.174230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208350265, states[0] = -94.256934, states[40]= 0.000001
Saving checkpoint... 
Iteration: 219587993, states[0] = -94.239769, states[40]= 0.000001
Saving checkpoint... 
Iteration: 230701086, states[0] = -94.240075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 241224387, states[0] = -94.260648, states[40]= 0.000001
Saving checkpoint... 
Iteration: 251677003, states[0] = -94.240186, states[40]= 0.000001
Saving checkpoint... 
Iteration: 261825077, states[0] = -94.269277, states[40]= 0.000001
Saving checkpoint... 
Iteration: 270192517, states[0] = -21.351123, states[40]= 0.003877
Saving checkpoint... 
Iteration: 281142005, states[0] = -94.243489, states[40]= 0.000001
Saving checkpoint... 
Iteration: 291679084, states[0] = -94.260177, states[40]= 0.000001
Saving checkpoint... 
Iteration: 302501784, states[0] = -94.240794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 312620069, states[0] = -94.249003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 322826210, states[0] = -94.247063, states[40]= 0.000001
Saving checkpoint... 
Iteration: 332509601, states[0] = -94.240582, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_MID_6000-conf_81.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_MID_6000-conf_81_0_r1363436009_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_MID_6000-conf_81_0_r1363436009_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.423789
     * GNaL_b in INaL: 0.006075
     * Gto_b in Ito: 0.085483
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031563
     * GKs_b in IKs: 0.001944
     * GK1_b in IK1: 0.164529
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.639203
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035719
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 332509601
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.240582 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 342555905, states[0] = -94.226747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353246222, states[0] = -94.242177, states[40]= 0.000001
Saving checkpoint... 
Iteration: 363322234, states[0] = -93.814109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373777408, states[0] = -94.247490, states[40]= 0.000001
Saving checkpoint... 
Iteration: 384531515, states[0] = -94.213872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394090673, states[0] = -94.263915, states[40]= 0.000001
Saving checkpoint... 
Iteration: 404609039, states[0] = -94.239642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 414577374, states[0] = -94.235204, states[40]= 0.000001
Saving checkpoint... 
Iteration: 424708868, states[0] = -94.248286, states[40]= 0.000001
Saving checkpoint... 
Iteration: 435577555, states[0] = -94.235130, states[40]= 0.000001
Saving checkpoint... 
Iteration: 446139062, states[0] = -94.242494, states[40]= 0.000001
Saving checkpoint... 
Iteration: 456297597, states[0] = -93.571222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465898185, states[0] = -94.267994, states[40]= 0.000001
Saving checkpoint... 
Iteration: 475674141, states[0] = -94.248555, states[40]= 0.000001
Saving checkpoint... 
Iteration: 485782352, states[0] = -94.238461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 495923576, states[0] = -94.267436, states[40]= 0.000001
Saving checkpoint... 
Iteration: 505989602, states[0] = -94.243672, states[40]= 0.000001
Saving checkpoint... 
Iteration: 515709290, states[0] = -94.238492, states[40]= 0.000001
Saving checkpoint... 
Iteration: 526545047, states[0] = -94.250758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 537340974, states[0] = -93.891120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547954691, states[0] = -94.243807, states[40]= 0.000001
Saving checkpoint... 
Iteration: 558001760, states[0] = 32.145866, states[40]= 1.666257
Saving checkpoint... 
Iteration: 567724246, states[0] = -94.263177, states[40]= 0.000001
Saving checkpoint... 
Iteration: 577782919, states[0] = -94.246012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 588440843, states[0] = -94.129208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598593325, states[0] = -94.249261, states[40]= 0.000001
Saving checkpoint... 
Iteration: 609110631, states[0] = 12.709613, states[40]= 0.000020
Saving checkpoint... 
Iteration: 619275717, states[0] = -94.256864, states[40]= 0.000001
Saving checkpoint... 
Iteration: 629468421, states[0] = -94.238793, states[40]= 0.000001
Saving checkpoint... 
Iteration: 640528693, states[0] = -94.250329, states[40]= 0.000001
Saving checkpoint... 
Iteration: 651468608, states[0] = -94.162301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661561397, states[0] = -94.249485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 671719056, states[0] = -94.237386, states[40]= 0.000001
Saving checkpoint... 
Iteration: 682165395, states[0] = -94.259689, states[40]= 0.000001
Saving checkpoint... 
Iteration: 692649354, states[0] = -94.237500, states[40]= 0.000001
Saving checkpoint... 
Iteration: 702959378, states[0] = -94.265331, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713291415, states[0] = -94.239369, states[40]= 0.000001
Saving checkpoint... 
Iteration: 723756722, states[0] = -94.264235, states[40]= 0.000001
Saving checkpoint... 
Iteration: 733971096, states[0] = -94.242327, states[40]= 0.000001
Saving checkpoint... 
Iteration: 743595794, states[0] = -94.237374, states[40]= 0.000001
Saving checkpoint... 
Iteration: 753958492, states[0] = -94.265001, states[40]= 0.000001
Saving checkpoint... 
Iteration: 764258864, states[0] = -94.239269, states[40]= 0.000001
Saving checkpoint... 
Iteration: 774640595, states[0] = -94.250502, states[40]= 0.000001
Saving checkpoint... 
Iteration: 784782033, states[0] = -94.244604, states[40]= 0.000001
Saving checkpoint... 
Iteration: 794802752, states[0] = -94.236278, states[40]= 0.000001
Saving checkpoint... 
Iteration: 805347877, states[0] = -94.253591, states[40]= 0.000001
Saving checkpoint... 
Iteration: 816072716, states[0] = 26.086997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826331375, states[0] = -94.253892, states[40]= 0.000001
Saving checkpoint... 
Iteration: 836342217, states[0] = -94.238158, states[40]= 0.000001
Saving checkpoint... 
Iteration: 846535488, states[0] = -94.212955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857145384, states[0] = -94.239612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 867047761, states[0] = 32.775919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877476602, states[0] = -94.249877, states[40]= 0.000001
Saving checkpoint... 
Iteration: 887264650, states[0] = -94.238378, states[40]= 0.000001
Saving checkpoint... 
Iteration: 897688762, states[0] = -94.257353, states[40]= 0.000001
Saving checkpoint... 
Iteration: 908261202, states[0] = -94.238261, states[40]= 0.000001
Saving checkpoint... 
Iteration: 918773355, states[0] = -94.263659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 929062672, states[0] = -94.239945, states[40]= 0.000001
Saving checkpoint... 
Iteration: 939748729, states[0] = -94.262314, states[40]= 0.000001
Saving checkpoint... 
Iteration: 950180743, states[0] = -94.238648, states[40]= 0.000001
Saving checkpoint... 
Iteration: 960978391, states[0] = -94.263129, states[40]= 0.000001
Saving checkpoint... 
Iteration: 970971736, states[0] = -94.240691, states[40]= 0.000001
Saving checkpoint... 
Iteration: 982021915, states[0] = -94.261867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 992411794, states[0] = -94.236630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1003271948, states[0] = -94.254335, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1013682583, states[0] = -94.235165, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1024165460, states[0] = -94.257340, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1034646405, states[0] = -94.235161, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1045413038, states[0] = -94.250257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1055085645, states[0] = -94.238839, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1065649934, states[0] = -94.250312, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1075866469, states[0] = -94.241347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1086127394, states[0] = 6.719327, states[40]= 0.000080
Saving checkpoint... 
Iteration: 1095435247, states[0] = -94.117751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105519491, states[0] = -94.247339, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1115411701, states[0] = -94.235786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1126519667, states[0] = -94.247191, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1136414745, states[0] = -94.235623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1146357600, states[0] = -93.945169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156586990, states[0] = -94.245557, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1166537759, states[0] = -94.234738, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1177399737, states[0] = -94.249686, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1187402854, states[0] = -94.235346, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1197726832, states[0] = -94.259060, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1208392210, states[0] = -94.235269, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1218437970, states[0] = -94.120815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228341195, states[0] = -94.250867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1238126517, states[0] = -94.237174, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1248921866, states[0] = -94.262301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1258653273, states[0] = -94.243564, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1268938565, states[0] = -94.232690, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1279436239, states[0] = -94.248079, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1289374865, states[0] = -94.234825, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1299151700, states[0] = -2.513697, states[40]= 0.000383
Saving checkpoint... 
Iteration: 1309599493, states[0] = -94.244254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1316366481, states[0] = -94.234694, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1326798437, states[0] = -94.261669, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1337213942, states[0] = -94.235700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1347114217, states[0] = 11.425947, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1357778835, states[0] = -94.240719, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1368235503, states[0] = -38.339784, states[40]= 0.002474
Saving checkpoint... 
Iteration: 1378235548, states[0] = -94.252818, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1388802594, states[0] = -94.232194, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1399767278, states[0] = -94.240615, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1410186257, states[0] = -19.452407, states[40]= 0.002333
Saving checkpoint... 
Iteration: 1420844980, states[0] = -94.239283, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1431874356, states[0] = -94.261570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1442349356, states[0] = -94.233943, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1452882332, states[0] = -94.261375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1463628218, states[0] = -94.232286, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1474717505, states[0] = -94.240928, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1484748988, states[0] = -94.231697, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1491810684, states[0] = -94.260803, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1498602213, states[0] = -94.242902, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.106968
 - CaMKt in component CaMK (millimolar): 0.001355
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 7.702605
 - nass in component intracellular_ions (millimolar): 7.702753
 - ki in component intracellular_ions (millimolar): 144.135095
 - kss in component intracellular_ions (millimolar): 144.135082
 - cansr in component intracellular_ions (millimolar): 1.761426
 - cajsr in component intracellular_ions (millimolar): 1.762650
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003921
 - hf in component INa (dimensionless): 0.865508
 - hs in component INa (dimensionless): 0.865508
 - j in component INa (dimensionless): 0.865509
 - hsp in component INa (dimensionless): 0.699114
 - jp in component INa (dimensionless): 0.865509
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707701
 - hLp in component INaL (dimensionless): 0.514054
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.999131
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999680
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999261
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004205
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000650
 - xs1 in component IKs (dimensionless): 0.019929
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997538
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
01:58:50 (60930): called boinc_finish(0)

</stderr_txt>
]]>


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