𝕏

Task 55856303

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-BASE_MID-conf_781_1
Workunit 26524790
Created 3 Jul 2024, 5:15:05 UTC
Sent 3 Jul 2024, 8:04:03 UTC
Report deadline 6 Jul 2024, 8:04:03 UTC
Received 4 Jul 2024, 11:36:43 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215831
Run time 3 hours 1 min 55 sec
CPU time 2 hours 26 min 5 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 2.83 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.81 MB
Peak swap size 6.23 MB
Peak disk usage 0.32 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-BASE_MID-conf_781.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-BASE_MID-conf_781_1_r1364510487_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-BASE_MID-conf_781_1_r1364510487_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 104.996588
     * GNaL_b in INaL: 0.006228
     * Gto_b in Ito: 0.083104
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031761
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.164617
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.386597
     * GKb_b in IKb: 0.003780
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028896
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 5325015, states[0] = -86.689010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 13523977, states[0] = 33.273392, states[40]= 0.000001
Saving checkpoint... 
Iteration: 21510872, states[0] = 28.994815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29501587, states[0] = 31.305218, states[40]= 1.783725
Saving checkpoint... 
Iteration: 37412465, states[0] = -86.863776, states[40]= 0.000002
Saving checkpoint... 
Iteration: 43977724, states[0] = -86.915699, states[40]= 0.000002
Saving checkpoint... 
Iteration: 46347035, states[0] = -86.795526, states[40]= 0.000002
Saving checkpoint... 
Iteration: 54253251, states[0] = -86.493066, states[40]= 0.000001
Saving checkpoint... 
Iteration: 62248263, states[0] = -86.474755, states[40]= 0.000001
Saving checkpoint... 
Iteration: 70550075, states[0] = 27.365025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79510805, states[0] = 28.487623, states[40]= -0.000000
Saving checkpoint... 
Iteration: 87006856, states[0] = 24.593094, states[40]= -0.000000
Saving checkpoint... 
Iteration: 95785912, states[0] = -86.679730, states[40]= 0.000001
Saving checkpoint... 
Iteration: 104293484, states[0] = -86.710030, states[40]= 0.000001
Saving checkpoint... 
Iteration: 112662624, states[0] = -40.665157, states[40]= 0.000328
Saving checkpoint... 
Iteration: 120525848, states[0] = 31.836754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129311968, states[0] = -86.771804, states[40]= 0.000002
Saving checkpoint... 
Iteration: 138675596, states[0] = -54.445690, states[40]= 0.000071
Saving checkpoint... 
Iteration: 148023414, states[0] = 31.827154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158130924, states[0] = -15.034955, states[40]= 0.000206
Saving checkpoint... 
Iteration: 167734294, states[0] = -86.421427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177783615, states[0] = -86.681571, states[40]= 0.000001
Saving checkpoint... 
Iteration: 188151575, states[0] = -31.703110, states[40]= 0.000595
Saving checkpoint... 
Iteration: 198688135, states[0] = -71.464308, states[40]= 0.000007
Saving checkpoint... 
Iteration: 208782200, states[0] = -86.675122, states[40]= 0.000001
Saving checkpoint... 
Iteration: 218847466, states[0] = -86.851030, states[40]= 0.000002
Saving checkpoint... 
Iteration: 228837980, states[0] = -86.832631, states[40]= 0.000002
Saving checkpoint... 
Iteration: 238664867, states[0] = -43.791867, states[40]= 0.000247
Saving checkpoint... 
Iteration: 248011859, states[0] = 29.031202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257435151, states[0] = -86.948069, states[40]= 0.000002
Saving checkpoint... 
Iteration: 267212828, states[0] = -86.236891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277068577, states[0] = 20.205416, states[40]= 0.000001
Saving checkpoint... 
Iteration: 286977623, states[0] = -86.968729, states[40]= 0.000002
Saving checkpoint... 
Iteration: 295595472, states[0] = 8.113559, states[40]= 0.000031
Saving checkpoint... 
Iteration: 304565958, states[0] = 21.250255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 314513527, states[0] = 29.889709, states[40]= -0.000000
Saving checkpoint... 
Iteration: 324605061, states[0] = 3.158113, states[40]= 0.000076
Saving checkpoint... 
Iteration: 334539372, states[0] = 29.824301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344760505, states[0] = -86.570284, states[40]= 0.000001
Saving checkpoint... 
Iteration: 354552643, states[0] = 26.088825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364183320, states[0] = -64.391867, states[40]= 0.000019
Saving checkpoint... 
Iteration: 374022653, states[0] = 31.783889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383371927, states[0] = -86.879865, states[40]= 0.000002
Saving checkpoint... 
Iteration: 393194240, states[0] = -80.896387, states[40]= 0.000002
Saving checkpoint... 
Iteration: 403216109, states[0] = -86.265181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413015378, states[0] = 30.606254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422704766, states[0] = -85.964909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432279363, states[0] = -86.651100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 442243883, states[0] = -86.470254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 452358336, states[0] = -86.855955, states[40]= 0.000002
Saving checkpoint... 
Iteration: 462415172, states[0] = -86.921363, states[40]= 0.000002
Saving checkpoint... 
Iteration: 472353583, states[0] = -86.847069, states[40]= 0.000002
Saving checkpoint... 
Iteration: 481840314, states[0] = -86.822606, states[40]= 0.000002
Saving checkpoint... 
Iteration: 489721282, states[0] = -86.305755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496989253, states[0] = -86.960949, states[40]= 0.000002
Saving checkpoint... 
Iteration: 505631677, states[0] = -15.829578, states[40]= 0.000210
Saving checkpoint... 
Iteration: 513242709, states[0] = -86.458610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 522448052, states[0] = -86.940652, states[40]= 0.000002
Saving checkpoint... 
Iteration: 531399494, states[0] = -86.903134, states[40]= 0.000002
Saving checkpoint... 
Iteration: 540479962, states[0] = -86.954914, states[40]= 0.000002
Saving checkpoint... 
Iteration: 549129393, states[0] = -13.894094, states[40]= 0.000202
Saving checkpoint... 
Iteration: 556505630, states[0] = 22.487519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564942127, states[0] = -86.934647, states[40]= 0.000002
Saving checkpoint... 
Iteration: 573538467, states[0] = 30.030362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581470720, states[0] = -86.948633, states[40]= 0.000002
Saving checkpoint... 
Iteration: 589204288, states[0] = -85.911734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596443928, states[0] = -86.933893, states[40]= 0.000002
Saving checkpoint... 
Iteration: 604022012, states[0] = 31.761158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611084868, states[0] = 13.162887, states[40]= 0.000010
Saving checkpoint... 
Iteration: 614975400, states[0] = -86.948695, states[40]= 0.000002
Saving checkpoint... 
Iteration: 621199025, states[0] = -84.731783, states[40]= 0.000001
Saving checkpoint... 
Iteration: 629383988, states[0] = -86.880661, states[40]= 0.000002
Saving checkpoint... 
Iteration: 637592289, states[0] = 9.676320, states[40]= 0.000023
Saving checkpoint... 
Iteration: 645840130, states[0] = -86.812620, states[40]= 0.000002
Saving checkpoint... 
Iteration: 654501700, states[0] = 29.477278, states[40]= 2.084573
Saving checkpoint... 
Iteration: 663143816, states[0] = -25.527256, states[40]= 0.000518
Saving checkpoint... 
Iteration: 671699006, states[0] = -84.716155, states[40]= 0.000001
Saving checkpoint... 
Iteration: 680101072, states[0] = 5.292420, states[40]= 0.000053
Saving checkpoint... 
Iteration: 689020771, states[0] = 31.674825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697416988, states[0] = -86.909113, states[40]= 0.000002
Saving checkpoint... 
Iteration: 704046525, states[0] = 27.986184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711897308, states[0] = -86.890369, states[40]= 0.000002
Saving checkpoint... 
Iteration: 717527895, states[0] = 31.659258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724721216, states[0] = -86.290929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732151003, states[0] = -31.264653, states[40]= 0.000598
Saving checkpoint... 
Iteration: 738542368, states[0] = 29.114120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745770932, states[0] = -86.596399, states[40]= 0.000001
Saving checkpoint... 
Iteration: 753917952, states[0] = -86.906611, states[40]= 0.000002
Saving checkpoint... 
Iteration: 761304884, states[0] = -86.720464, states[40]= 0.000002
Saving checkpoint... 
Iteration: 769333143, states[0] = -86.791152, states[40]= 0.000002
Saving checkpoint... 
Iteration: 776834281, states[0] = -86.793097, states[40]= 0.000002
Saving checkpoint... 
Iteration: 784653544, states[0] = -33.398551, states[40]= 0.000556
Saving checkpoint... 
Iteration: 794155203, states[0] = -34.828588, states[40]= 0.000517
Saving checkpoint... 
Iteration: 802977050, states[0] = -86.938428, states[40]= 0.000002
Saving checkpoint... 
Iteration: 810862379, states[0] = -86.841146, states[40]= 0.000002
Saving checkpoint... 
Iteration: 819268030, states[0] = -86.578683, states[40]= 0.000001
Saving checkpoint... 
Iteration: 827009401, states[0] = 27.304408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835555187, states[0] = 25.245293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843641019, states[0] = -23.344955, states[40]= 0.000420
Saving checkpoint... 
Iteration: 850749846, states[0] = -86.481689, states[40]= 0.000001
Saving checkpoint... 
Iteration: 858722731, states[0] = -86.295127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865908783, states[0] = -86.892300, states[40]= 0.000002
Saving checkpoint... 
Iteration: 874821082, states[0] = -86.757474, states[40]= 0.000002
Saving checkpoint... 
Iteration: 883021784, states[0] = 31.755122, states[40]= -0.000000
Saving checkpoint... 
Iteration: 891444489, states[0] = -86.917038, states[40]= 0.000002
Saving checkpoint... 
Iteration: 899026363, states[0] = 31.761706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906142972, states[0] = -24.852124, states[40]= 0.000488
Saving checkpoint... 
Iteration: 913494539, states[0] = -86.938497, states[40]= 0.000002
Saving checkpoint... 
Iteration: 920403715, states[0] = -86.884454, states[40]= 0.000002
Saving checkpoint... 
Iteration: 927338607, states[0] = -86.793050, states[40]= 0.000002
Saving checkpoint... 
Iteration: 934376592, states[0] = -86.853691, states[40]= 0.000002
Saving checkpoint... 
Iteration: 941213578, states[0] = -86.204751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948401075, states[0] = -86.880276, states[40]= 0.000002
Saving checkpoint... 
Iteration: 956044875, states[0] = 28.456082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963278774, states[0] = -86.617087, states[40]= 0.000001
Saving checkpoint... 
Iteration: 970251248, states[0] = -86.482625, states[40]= 0.000001
Saving checkpoint... 
Iteration: 976749990, states[0] = -86.474965, states[40]= 0.000001
Saving checkpoint... 
Iteration: 984530624, states[0] = 31.392018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992317474, states[0] = -86.741524, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1000245538, states[0] = -86.446968, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1008096247, states[0] = 7.752715, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1016213152, states[0] = -86.194834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024526062, states[0] = 31.778780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034487661, states[0] = -86.929051, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1044577867, states[0] = 16.313566, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1054686525, states[0] = -68.862113, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1064640051, states[0] = -22.573418, states[40]= 0.000383
Saving checkpoint... 
Iteration: 1074299578, states[0] = -86.685643, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1083743739, states[0] = -86.430747, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1093397697, states[0] = -86.868447, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1102648130, states[0] = -28.886830, states[40]= 0.000600
Saving checkpoint... 
Iteration: 1111823342, states[0] = -86.748961, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1120619964, states[0] = -6.196323, states[40]= 0.000187
Saving checkpoint... 
Iteration: 1129760536, states[0] = -86.523485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1138976804, states[0] = -86.918762, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1147877784, states[0] = -86.842715, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1157044343, states[0] = 28.606010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166989675, states[0] = -86.922059, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1176656098, states[0] = -35.573958, states[40]= 0.000491
Saving checkpoint... 
Iteration: 1186030633, states[0] = 31.395736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195363265, states[0] = -86.819929, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1204686887, states[0] = -69.379178, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1214451908, states[0] = -86.902432, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1224314333, states[0] = -86.719627, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1234240821, states[0] = -86.403094, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1243706694, states[0] = -86.024032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253587438, states[0] = 11.993178, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1263711894, states[0] = -86.161999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273715604, states[0] = -86.206832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283613266, states[0] = -1.582927, states[40]= 0.000138
Saving checkpoint... 
Iteration: 1293682348, states[0] = -62.908209, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1303741297, states[0] = -86.401968, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1313582426, states[0] = 14.294371, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1322997438, states[0] = -86.915605, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1331857839, states[0] = -86.803550, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1341803487, states[0] = -86.681949, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1351926760, states[0] = -86.878453, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1361734183, states[0] = -86.350594, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1370434393, states[0] = -86.882709, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1380254012, states[0] = -86.473674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1389263771, states[0] = -86.524237, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1398361901, states[0] = -86.805983, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1407922112, states[0] = -86.871688, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1417175515, states[0] = -54.725566, states[40]= 0.000068
Saving checkpoint... 
Iteration: 1425548001, states[0] = 27.571010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434555118, states[0] = 25.283141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443827223, states[0] = -86.738423, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1452504627, states[0] = 19.940220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461761677, states[0] = -86.509431, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1470286636, states[0] = -86.617685, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1478446539, states[0] = -86.884030, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1487263027, states[0] = -86.514724, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1495580492, states[0] = 15.167062, states[40]= 0.000006
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.782023
 - CaMKt in component CaMK (millimolar): 0.025512
 - cass in component intracellular_ions (millimolar): 0.000094
 - nai in component intracellular_ions (millimolar): 8.105145
 - nass in component intracellular_ions (millimolar): 8.105300
 - ki in component intracellular_ions (millimolar): 143.259855
 - kss in component intracellular_ions (millimolar): 143.259817
 - cansr in component intracellular_ions (millimolar): 2.080441
 - cajsr in component intracellular_ions (millimolar): 2.017300
 - cai in component intracellular_ions (millimolar): 0.000097
 - m in component INa (dimensionless): 0.008199
 - hf in component INa (dimensionless): 0.658868
 - hs in component INa (dimensionless): 0.658838
 - j in component INa (dimensionless): 0.658663
 - hsp in component INa (dimensionless): 0.410738
 - jp in component INa (dimensionless): 0.658538
 - mL in component INaL (dimensionless): 0.000232
 - hL in component INaL (dimensionless): 0.454977
 - hLp in component INaL (dimensionless): 0.221177
 - a in component Ito (dimensionless): 0.001078
 - iF in component Ito (dimensionless): 0.999460
 - iS in component Ito (dimensionless): 0.532660
 - ap in component Ito (dimensionless): 0.000549
 - iFp in component Ito (dimensionless): 0.999460
 - iSp in component Ito (dimensionless): 0.576084
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.876238
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999606
 - jca in component ICaL (dimensionless): 0.999939
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003988
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.510377
 - xs1 in component IKs (dimensionless): 0.335029
 - xs2 in component IKs (dimensionless): 0.000218
 - xk1 in component IK1 (dimensionless): 0.997036
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
06:36:28 (8640): called boinc_finish(0)

</stderr_txt>
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