𝕏

Task 55850399

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pieske_333-conf_570_1
Workunit 26521838
Created 3 Jul 2024, 5:12:19 UTC
Sent 3 Jul 2024, 7:30:31 UTC
Report deadline 6 Jul 2024, 7:30:31 UTC
Received 3 Jul 2024, 23:07:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 40 min 11 sec
CPU time 2 hours 0 min 18 sec
Validate state Valid
Credit 44.31
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.80 MB
Peak swap size 32.60 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pieske_333-conf_570.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pieske_333-conf_570_1_r1291222356_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pieske_333-conf_570_1_r1291222356_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.067853
     * GNaL_b in INaL: 0.006108
     * Gto_b in Ito: 0.084082
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032086
     * GKs_b in IKs: 0.001898
     * GK1_b in IK1: 0.166992
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.931268
     * GKb_b in IKb: 0.003829
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029479
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 6647728, states[0] = -87.772775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16045656, states[0] = 0.320779, states[40]= 0.005870
Saving checkpoint... 
Iteration: 25531646, states[0] = 10.533126, states[40]= 0.007635
Saving checkpoint... 
Iteration: 35075548, states[0] = -41.651108, states[40]= 0.000126
Saving checkpoint... 
Iteration: 44659414, states[0] = -87.797293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54721919, states[0] = -16.328839, states[40]= 0.001797
Saving checkpoint... 
Iteration: 64605251, states[0] = -86.774881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75016552, states[0] = 16.492428, states[40]= 0.009354
Saving checkpoint... 
Iteration: 82355072, states[0] = 13.114208, states[40]= 0.008135
Saving checkpoint... 
Iteration: 92768920, states[0] = -86.760983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102374847, states[0] = -4.636420, states[40]= 0.004872
Saving checkpoint... 
Iteration: 111833824, states[0] = 21.902063, states[40]= 0.033538
Saving checkpoint... 
Iteration: 121781197, states[0] = -87.670655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129112246, states[0] = -87.659694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139494787, states[0] = 23.315881, states[40]= 0.061149
Saving checkpoint... 
Iteration: 148742286, states[0] = -58.625759, states[40]= 0.000010
Saving checkpoint... 
Iteration: 157724298, states[0] = -34.370959, states[40]= 0.000326
Saving checkpoint... 
Iteration: 167754253, states[0] = -81.558767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177957556, states[0] = -87.739415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188228192, states[0] = -43.980132, states[40]= 0.000093
Saving checkpoint... 
Iteration: 198504121, states[0] = 16.505309, states[40]= 0.009371
Saving checkpoint... 
Iteration: 208759101, states[0] = -87.141956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218762203, states[0] = -87.506907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225384114, states[0] = -34.264086, states[40]= 0.000330
Saving checkpoint... 
Iteration: 234981975, states[0] = 26.716475, states[40]= 0.112026
Saving checkpoint... 
Iteration: 243471074, states[0] = -87.802956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252344796, states[0] = 8.667956, states[40]= 0.007407
Saving checkpoint... 
Iteration: 261195262, states[0] = -8.309353, states[40]= 0.003784
Saving checkpoint... 
Iteration: 270186163, states[0] = 0.764851, states[40]= 0.006197
Saving checkpoint... 
Iteration: 279452080, states[0] = -87.755854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289080270, states[0] = -85.911293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298998570, states[0] = 13.988575, states[40]= 0.008351
Saving checkpoint... 
Iteration: 309107393, states[0] = -87.725429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319200246, states[0] = -23.366662, states[40]= 0.000942
Saving checkpoint... 
Iteration: 327875720, states[0] = -36.820007, states[40]= 0.000243
Saving checkpoint... 
Iteration: 337183231, states[0] = -3.026436, states[40]= 0.005318
Saving checkpoint... 
Iteration: 347214927, states[0] = -47.688386, states[40]= 0.000054
Saving checkpoint... 
Iteration: 356660172, states[0] = 13.570770, states[40]= 0.008244
Saving checkpoint... 
Iteration: 366517722, states[0] = -7.872563, states[40]= 0.003915
Saving checkpoint... 
Iteration: 375664593, states[0] = 9.506953, states[40]= 0.007523
Saving checkpoint... 
Iteration: 386102264, states[0] = -87.734998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397309171, states[0] = 20.372128, states[40]= 0.017610
Saving checkpoint... 
Iteration: 408862381, states[0] = -29.580167, states[40]= 0.000543
Saving checkpoint... 
Iteration: 419685479, states[0] = -16.666526, states[40]= 0.001743
Saving checkpoint... 
Iteration: 429528514, states[0] = -31.707691, states[40]= 0.000438
Saving checkpoint... 
Iteration: 439397993, states[0] = -85.597375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449065212, states[0] = -86.327339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458391606, states[0] = -81.228350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467142621, states[0] = 17.176058, states[40]= 0.009853
Saving checkpoint... 
Iteration: 475915704, states[0] = -87.689303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484779705, states[0] = -87.801073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493425899, states[0] = -87.738647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502470992, states[0] = 17.882954, states[40]= 0.010561
Saving checkpoint... 
Iteration: 511879952, states[0] = -70.597090, states[40]= 0.000002
Saving checkpoint... 
Iteration: 521489451, states[0] = 4.989318, states[40]= 0.006906
Saving checkpoint... 
Iteration: 532524691, states[0] = -40.645851, states[40]= 0.000147
Saving checkpoint... 
Iteration: 542919436, states[0] = -87.733074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550318885, states[0] = 5.787451, states[40]= 0.007019
Saving checkpoint... 
Iteration: 561396432, states[0] = -87.572108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572144466, states[0] = 9.832791, states[40]= 0.007570
Saving checkpoint... 
Iteration: 582368375, states[0] = -62.976057, states[40]= 0.000005
Saving checkpoint... 
Iteration: 592426498, states[0] = -87.774149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602499255, states[0] = -14.862411, states[40]= 0.002082
Saving checkpoint... 
Iteration: 613412026, states[0] = -87.731641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624879200, states[0] = -85.450385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636108835, states[0] = 26.202489, states[40]= 0.107195
Saving checkpoint... 
Iteration: 646985503, states[0] = -2.941357, states[40]= 0.005340
Saving checkpoint... 
Iteration: 656739179, states[0] = -87.724531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665282617, states[0] = 20.273384, states[40]= 0.017049
Saving checkpoint... 
Iteration: 673849844, states[0] = -48.990423, states[40]= 0.000045
Saving checkpoint... 
Iteration: 682720001, states[0] = -87.620846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692084189, states[0] = -87.777083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701173620, states[0] = -39.441762, states[40]= 0.000173
Saving checkpoint... 
Iteration: 709770686, states[0] = 23.573393, states[40]= 0.066473
Saving checkpoint... 
Iteration: 719394756, states[0] = -87.704714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729847470, states[0] = -53.632769, states[40]= 0.000022
Saving checkpoint... 
Iteration: 737374117, states[0] = -87.298436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747798017, states[0] = 6.644510, states[40]= 0.007136
Saving checkpoint... 
Iteration: 757903986, states[0] = -87.754318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768280956, states[0] = 16.248517, states[40]= 0.009220
Saving checkpoint... 
Iteration: 778899742, states[0] = -87.746850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789052346, states[0] = -87.695125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798848623, states[0] = -66.078568, states[40]= 0.000003
Saving checkpoint... 
Iteration: 808224914, states[0] = -87.727649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816972546, states[0] = -7.710131, states[40]= 0.003964
Saving checkpoint... 
Iteration: 825253544, states[0] = 35.370480, states[40]= 0.109204
Saving checkpoint... 
Iteration: 832993382, states[0] = -38.904542, states[40]= 0.000186
Saving checkpoint... 
Iteration: 840929268, states[0] = 21.231621, states[40]= 0.024623
Saving checkpoint... 
Iteration: 849522732, states[0] = -85.001742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858675819, states[0] = -65.821602, states[40]= 0.000003
Saving checkpoint... 
Iteration: 868793336, states[0] = 0.415800, states[40]= 0.006127
Saving checkpoint... 
Iteration: 875915781, states[0] = 32.492804, states[40]= 0.121592
Saving checkpoint... 
Iteration: 886586790, states[0] = 23.282241, states[40]= 0.060474
Saving checkpoint... 
Iteration: 897134863, states[0] = -12.624489, states[40]= 0.002589
Saving checkpoint... 
Iteration: 907552149, states[0] = -87.741719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917946438, states[0] = 7.558570, states[40]= 0.007258
Saving checkpoint... 
Iteration: 928287892, states[0] = -0.067327, states[40]= 0.006026
Saving checkpoint... 
Iteration: 937898941, states[0] = -87.794536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947894433, states[0] = -87.784278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957731787, states[0] = -87.798729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967374115, states[0] = -87.721441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976685082, states[0] = -87.432084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985441531, states[0] = 6.177829, states[40]= 0.007072
Saving checkpoint... 
Iteration: 994052796, states[0] = -87.772896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002908316, states[0] = 23.390105, states[40]= 0.062712
Saving checkpoint... 
Iteration: 1011927871, states[0] = 13.632099, states[40]= 0.008259
Saving checkpoint... 
Iteration: 1021337387, states[0] = -83.716135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030982232, states[0] = -51.043305, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1041023543, states[0] = -87.676049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051123465, states[0] = -18.282073, states[40]= 0.001490
Saving checkpoint... 
Iteration: 1061494211, states[0] = -75.146993, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1071505756, states[0] = -87.076433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081566212, states[0] = 24.033983, states[40]= 0.075538
Saving checkpoint... 
Iteration: 1091791840, states[0] = -26.449391, states[40]= 0.000723
Saving checkpoint... 
Iteration: 1102077225, states[0] = 18.106945, states[40]= 0.010844
Saving checkpoint... 
Iteration: 1112464065, states[0] = -37.025340, states[40]= 0.000236
Saving checkpoint... 
Iteration: 1122543823, states[0] = -87.784759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132469208, states[0] = -46.955038, states[40]= 0.000060
Saving checkpoint... 
Iteration: 1141721423, states[0] = 37.804034, states[40]= 0.094013
Saving checkpoint... 
Iteration: 1150323772, states[0] = -82.956382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158606490, states[0] = -9.594947, states[40]= 0.003407
Saving checkpoint... 
Iteration: 1166925480, states[0] = 4.522993, states[40]= 0.006838
Saving checkpoint... 
Iteration: 1175583231, states[0] = 10.430176, states[40]= 0.007657
Saving checkpoint... 
Iteration: 1184785304, states[0] = -30.308750, states[40]= 0.000505
Saving checkpoint... 
Iteration: 1194615666, states[0] = -27.533974, states[40]= 0.000657
Saving checkpoint... 
Iteration: 1204409634, states[0] = 13.018230, states[40]= 0.008117
Saving checkpoint... 
Iteration: 1213158484, states[0] = -87.114366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223493290, states[0] = -87.400205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233872524, states[0] = -87.803095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244399536, states[0] = 16.497113, states[40]= 0.009365
Saving checkpoint... 
Iteration: 1254813275, states[0] = -82.901659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265090897, states[0] = -3.536955, states[40]= 0.005181
Saving checkpoint... 
Iteration: 1275087127, states[0] = -0.639166, states[40]= 0.005901
Saving checkpoint... 
Iteration: 1284774302, states[0] = -28.914454, states[40]= 0.000578
Saving checkpoint... 
Iteration: 1293739507, states[0] = 9.464352, states[40]= 0.007516
Saving checkpoint... 
Iteration: 1301268769, states[0] = -23.463595, states[40]= 0.000934
Saving checkpoint... 
Iteration: 1308960930, states[0] = -60.700818, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1317360716, states[0] = -87.793334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326334954, states[0] = -87.707790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335880706, states[0] = 20.868758, states[40]= 0.021137
Saving checkpoint... 
Iteration: 1345623046, states[0] = -59.337337, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1356406044, states[0] = 4.914480, states[40]= 0.006896
Saving checkpoint... 
Iteration: 1367286765, states[0] = -58.148943, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1377946250, states[0] = -49.209789, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1388218699, states[0] = 16.385122, states[40]= 0.009298
Saving checkpoint... 
Iteration: 1395278569, states[0] = -50.235876, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1406094595, states[0] = -27.646173, states[40]= 0.000650
Saving checkpoint... 
Iteration: 1416961998, states[0] = -80.644771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427509630, states[0] = -87.772909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437529138, states[0] = 25.553321, states[40]= 0.099690
Saving checkpoint... 
Iteration: 1447074610, states[0] = -5.744872, states[40]= 0.004551
Saving checkpoint... 
Iteration: 1456083941, states[0] = -19.669426, states[40]= 0.001308
Saving checkpoint... 
Iteration: 1465251798, states[0] = -22.658157, states[40]= 0.001001
Saving checkpoint... 
Iteration: 1474299313, states[0] = -87.156805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483575415, states[0] = -11.520271, states[40]= 0.002872
Saving checkpoint... 
Iteration: 1492648065, states[0] = -87.691431, states[40]= 0.000000
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.689102
 - CaMKt in component CaMK (millimolar): 0.042308
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 7.027901
 - nass in component intracellular_ions (millimolar): 7.028049
 - ki in component intracellular_ions (millimolar): 144.892562
 - kss in component intracellular_ions (millimolar): 144.892529
 - cansr in component intracellular_ions (millimolar): 1.619498
 - cajsr in component intracellular_ions (millimolar): 1.187942
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007485
 - hf in component INa (dimensionless): 0.691539
 - hs in component INa (dimensionless): 0.691304
 - j in component INa (dimensionless): 0.680975
 - hsp in component INa (dimensionless): 0.446293
 - jp in component INa (dimensionless): 0.654770
 - mL in component INaL (dimensionless): 0.000195
 - hL in component INaL (dimensionless): 0.293642
 - hLp in component INaL (dimensionless): 0.136563
 - a in component Ito (dimensionless): 0.001014
 - iF in component Ito (dimensionless): 0.999538
 - iS in component Ito (dimensionless): 0.175958
 - ap in component Ito (dimensionless): 0.000517
 - iFp in component Ito (dimensionless): 0.999539
 - iSp in component Ito (dimensionless): 0.212974
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.804169
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966795
 - jca in component ICaL (dimensionless): 0.948057
 - ffp in component ICaL (dimensionless): 0.999865
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009467
 - xrf in component IKr (dimensionless): 0.028535
 - xrs in component IKr (dimensionless): 0.787826
 - xs1 in component IKs (dimensionless): 0.458585
 - xs2 in component IKs (dimensionless): 0.001175
 - xk1 in component IK1 (dimensionless): 0.996814
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:00:58 (86506): called boinc_finish(0)

</stderr_txt>
]]>


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