𝕏

Task 55850397

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pieske_333-conf_470_1
Workunit 26521837
Created 3 Jul 2024, 5:12:19 UTC
Sent 3 Jul 2024, 7:30:31 UTC
Report deadline 6 Jul 2024, 7:30:31 UTC
Received 3 Jul 2024, 21:49:19 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 39 min 28 sec
CPU time 1 hours 59 min 40 sec
Validate state Valid
Credit 43.99
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.79 MB
Peak swap size 32.60 GB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pieske_333-conf_470.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pieske_333-conf_470_1_r1158749034_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pieske_333-conf_470_1_r1158749034_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.395264
     * GNaL_b in INaL: 0.005915
     * Gto_b in Ito: 0.083377
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032267
     * GKs_b in IKs: 0.001936
     * GK1_b in IK1: 0.160325
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.828728
     * GKb_b in IKb: 0.003816
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029351
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 6804334, states[0] = -87.728220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16630458, states[0] = -87.672503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26692141, states[0] = 14.264363, states[40]= 0.008496
Saving checkpoint... 
Iteration: 36774724, states[0] = -86.580843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46901870, states[0] = -34.271925, states[40]= 0.000327
Saving checkpoint... 
Iteration: 57304459, states[0] = -87.717123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67433262, states[0] = -83.779819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76755477, states[0] = -68.289949, states[40]= 0.000002
Saving checkpoint... 
Iteration: 87052416, states[0] = -17.423364, states[40]= 0.001623
Saving checkpoint... 
Iteration: 97159322, states[0] = 37.387496, states[40]= 0.097365
Saving checkpoint... 
Iteration: 105568001, states[0] = -41.905837, states[40]= 0.000124
Saving checkpoint... 
Iteration: 115203730, states[0] = -1.379688, states[40]= 0.005745
Saving checkpoint... 
Iteration: 124700265, states[0] = 1.066531, states[40]= 0.006272
Saving checkpoint... 
Iteration: 134236733, states[0] = -48.834865, states[40]= 0.000046
Saving checkpoint... 
Iteration: 143798225, states[0] = -87.731982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153642834, states[0] = -87.772312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163818494, states[0] = 41.288252, states[40]= 0.060281
Saving checkpoint... 
Iteration: 173854489, states[0] = 7.276790, states[40]= 0.007243
Saving checkpoint... 
Iteration: 184414683, states[0] = -74.099729, states[40]= 0.000001
Saving checkpoint... 
Iteration: 191794632, states[0] = -87.736415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201810366, states[0] = -87.788845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211207386, states[0] = -18.523970, states[40]= 0.001460
Saving checkpoint... 
Iteration: 220989501, states[0] = 22.002588, states[40]= 0.034035
Saving checkpoint... 
Iteration: 230208913, states[0] = -23.420307, states[40]= 0.000939
Saving checkpoint... 
Iteration: 241033174, states[0] = -12.037399, states[40]= 0.002745
Saving checkpoint... 
Iteration: 250871306, states[0] = -20.271713, states[40]= 0.001240
Saving checkpoint... 
Iteration: 259642192, states[0] = 41.437222, states[40]= 0.057401
Saving checkpoint... 
Iteration: 269459433, states[0] = -87.756264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279668634, states[0] = 13.095062, states[40]= 0.008162
Saving checkpoint... 
Iteration: 289877451, states[0] = -34.411944, states[40]= 0.000324
Saving checkpoint... 
Iteration: 300226576, states[0] = -58.155567, states[40]= 0.000011
Saving checkpoint... 
Iteration: 310525798, states[0] = -11.448819, states[40]= 0.002899
Saving checkpoint... 
Iteration: 320697981, states[0] = -20.739242, states[40]= 0.001188
Saving checkpoint... 
Iteration: 330282677, states[0] = -87.742903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339984810, states[0] = 19.046695, states[40]= 0.012481
Saving checkpoint... 
Iteration: 348511806, states[0] = 0.501734, states[40]= 0.006161
Saving checkpoint... 
Iteration: 357406503, states[0] = -85.558010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366279784, states[0] = -87.745212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375283831, states[0] = -87.761381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384563465, states[0] = -77.692130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394200745, states[0] = -34.954781, states[40]= 0.000304
Saving checkpoint... 
Iteration: 404151359, states[0] = 15.904242, states[40]= 0.009064
Saving checkpoint... 
Iteration: 414310333, states[0] = 19.215478, states[40]= 0.012888
Saving checkpoint... 
Iteration: 424435946, states[0] = -87.728687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433365287, states[0] = -37.431171, states[40]= 0.000224
Saving checkpoint... 
Iteration: 442666885, states[0] = 2.484142, states[40]= 0.006533
Saving checkpoint... 
Iteration: 452721545, states[0] = -74.721574, states[40]= 0.000001
Saving checkpoint... 
Iteration: 462181629, states[0] = -17.581975, states[40]= 0.001599
Saving checkpoint... 
Iteration: 472045248, states[0] = -61.971094, states[40]= 0.000006
Saving checkpoint... 
Iteration: 481251898, states[0] = -87.681701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491713068, states[0] = -66.941856, states[40]= 0.000003
Saving checkpoint... 
Iteration: 502951102, states[0] = 41.634598, states[40]= 0.052255
Saving checkpoint... 
Iteration: 514575409, states[0] = -87.645689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525507118, states[0] = -15.415331, states[40]= 0.001978
Saving checkpoint... 
Iteration: 535362227, states[0] = -47.361102, states[40]= 0.000057
Saving checkpoint... 
Iteration: 545242839, states[0] = -87.668809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554950598, states[0] = 25.854367, states[40]= 0.101978
Saving checkpoint... 
Iteration: 564325322, states[0] = -1.234753, states[40]= 0.005780
Saving checkpoint... 
Iteration: 573118222, states[0] = 23.326060, states[40]= 0.059450
Saving checkpoint... 
Iteration: 581921210, states[0] = -87.732224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590839218, states[0] = -23.003508, states[40]= 0.000973
Saving checkpoint... 
Iteration: 599512805, states[0] = -33.932530, states[40]= 0.000342
Saving checkpoint... 
Iteration: 608600088, states[0] = -87.780093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618087010, states[0] = -87.741784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627770792, states[0] = -57.979293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638803295, states[0] = 10.586949, states[40]= 0.007707
Saving checkpoint... 
Iteration: 649269357, states[0] = 40.691118, states[40]= 0.024254
Saving checkpoint... 
Iteration: 656764853, states[0] = -87.788311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667881746, states[0] = -87.286245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678692012, states[0] = -63.163588, states[40]= 0.000005
Saving checkpoint... 
Iteration: 688913384, states[0] = -87.742094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699010750, states[0] = -44.868873, states[40]= 0.000081
Saving checkpoint... 
Iteration: 709090997, states[0] = -87.782662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719927698, states[0] = -87.794989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731392031, states[0] = -87.674217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742693013, states[0] = -75.519947, states[40]= 0.000001
Saving checkpoint... 
Iteration: 753525737, states[0] = -76.320888, states[40]= 0.000001
Saving checkpoint... 
Iteration: 763270046, states[0] = 21.422983, states[40]= 0.026059
Saving checkpoint... 
Iteration: 771862258, states[0] = -83.375472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780425312, states[0] = 32.685088, states[40]= 0.121260
Saving checkpoint... 
Iteration: 789292587, states[0] = 7.537738, states[40]= 0.007278
Saving checkpoint... 
Iteration: 798676102, states[0] = -57.226495, states[40]= 0.000013
Saving checkpoint... 
Iteration: 807796107, states[0] = 3.287688, states[40]= 0.006667
Saving checkpoint... 
Iteration: 816314490, states[0] = -19.890044, states[40]= 0.001284
Saving checkpoint... 
Iteration: 826040638, states[0] = -87.610787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836484716, states[0] = -27.806212, states[40]= 0.000640
Saving checkpoint... 
Iteration: 844023359, states[0] = -84.816343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854475186, states[0] = -16.803210, states[40]= 0.001725
Saving checkpoint... 
Iteration: 864611413, states[0] = 12.299169, states[40]= 0.007998
Saving checkpoint... 
Iteration: 875009633, states[0] = -69.551967, states[40]= 0.000002
Saving checkpoint... 
Iteration: 885649079, states[0] = -31.461799, states[40]= 0.000448
Saving checkpoint... 
Iteration: 895810448, states[0] = -25.454160, states[40]= 0.000788
Saving checkpoint... 
Iteration: 905676616, states[0] = -75.353623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 915093246, states[0] = 19.364233, states[40]= 0.013284
Saving checkpoint... 
Iteration: 923863351, states[0] = -87.598950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932161279, states[0] = -55.069405, states[40]= 0.000018
Saving checkpoint... 
Iteration: 939922233, states[0] = 20.155147, states[40]= 0.016212
Saving checkpoint... 
Iteration: 947885316, states[0] = -87.734138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956476518, states[0] = -33.114583, states[40]= 0.000375
Saving checkpoint... 
Iteration: 965625975, states[0] = -10.113501, states[40]= 0.003267
Saving checkpoint... 
Iteration: 975763594, states[0] = 14.352248, states[40]= 0.008480
Saving checkpoint... 
Iteration: 983000881, states[0] = -73.059828, states[40]= 0.000001
Saving checkpoint... 
Iteration: 993833255, states[0] = -73.273642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1004412448, states[0] = 21.481289, states[40]= 0.026746
Saving checkpoint... 
Iteration: 1014821708, states[0] = -58.049011, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1025231060, states[0] = -55.743729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035592751, states[0] = 13.269643, states[40]= 0.008200
Saving checkpoint... 
Iteration: 1045210497, states[0] = -87.739531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055236612, states[0] = 23.362920, states[40]= 0.060194
Saving checkpoint... 
Iteration: 1065119273, states[0] = -14.639997, states[40]= 0.002135
Saving checkpoint... 
Iteration: 1074801836, states[0] = -38.399148, states[40]= 0.000198
Saving checkpoint... 
Iteration: 1084120868, states[0] = -19.647186, states[40]= 0.001313
Saving checkpoint... 
Iteration: 1092893642, states[0] = 34.525500, states[40]= 0.114019
Saving checkpoint... 
Iteration: 1101528213, states[0] = -87.702454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110405318, states[0] = 20.099076, states[40]= 0.015947
Saving checkpoint... 
Iteration: 1119445775, states[0] = -12.670828, states[40]= 0.002585
Saving checkpoint... 
Iteration: 1128857595, states[0] = -87.697423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138526231, states[0] = -87.709195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148577624, states[0] = 15.508514, states[40]= 0.008886
Saving checkpoint... 
Iteration: 1158747060, states[0] = 13.295080, states[40]= 0.008205
Saving checkpoint... 
Iteration: 1169094971, states[0] = 1.828586, states[40]= 0.006417
Saving checkpoint... 
Iteration: 1179130993, states[0] = -47.102230, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1189220191, states[0] = 26.306683, states[40]= 0.107017
Saving checkpoint... 
Iteration: 1199494960, states[0] = -87.255464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209794396, states[0] = -46.825196, states[40]= 0.000061
Saving checkpoint... 
Iteration: 1220208155, states[0] = -87.786592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230314445, states[0] = -81.042432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240243822, states[0] = 10.131035, states[40]= 0.007638
Saving checkpoint... 
Iteration: 1249495683, states[0] = -87.565511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258139115, states[0] = -71.485906, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1266437350, states[0] = -21.622173, states[40]= 0.001098
Saving checkpoint... 
Iteration: 1274746100, states[0] = 5.975396, states[40]= 0.007066
Saving checkpoint... 
Iteration: 1283460684, states[0] = -56.833872, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1292696401, states[0] = -87.773488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302552770, states[0] = 20.098241, states[40]= 0.015945
Saving checkpoint... 
Iteration: 1312365651, states[0] = -87.786600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321089279, states[0] = -8.586716, states[40]= 0.003712
Saving checkpoint... 
Iteration: 1331471184, states[0] = -81.295098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341908133, states[0] = 4.311661, states[40]= 0.006827
Saving checkpoint... 
Iteration: 1352468861, states[0] = -80.995741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362902095, states[0] = 7.385012, states[40]= 0.007257
Saving checkpoint... 
Iteration: 1373191533, states[0] = -87.782631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383245199, states[0] = -3.112220, states[40]= 0.005308
Saving checkpoint... 
Iteration: 1392990515, states[0] = -87.662959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401976938, states[0] = -87.434611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409491435, states[0] = -87.675985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417206129, states[0] = 20.840924, states[40]= 0.020458
Saving checkpoint... 
Iteration: 1425627320, states[0] = -79.722795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434660783, states[0] = -87.698697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444239910, states[0] = -4.018212, states[40]= 0.005061
Saving checkpoint... 
Iteration: 1454013904, states[0] = -87.774090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464817355, states[0] = -87.666529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475745235, states[0] = -15.156837, states[40]= 0.002029
Saving checkpoint... 
Iteration: 1486441030, states[0] = -57.783620, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1496719644, states[0] = 9.116100, states[40]= 0.007493
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.670376
 - CaMKt in component CaMK (millimolar): 0.042238
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 7.003265
 - nass in component intracellular_ions (millimolar): 7.003413
 - ki in component intracellular_ions (millimolar): 144.917257
 - kss in component intracellular_ions (millimolar): 144.917225
 - cansr in component intracellular_ions (millimolar): 1.619184
 - cajsr in component intracellular_ions (millimolar): 1.188010
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007499
 - hf in component INa (dimensionless): 0.690882
 - hs in component INa (dimensionless): 0.690638
 - j in component INa (dimensionless): 0.680162
 - hsp in component INa (dimensionless): 0.445490
 - jp in component INa (dimensionless): 0.653842
 - mL in component INaL (dimensionless): 0.000196
 - hL in component INaL (dimensionless): 0.292776
 - hLp in component INaL (dimensionless): 0.135969
 - a in component Ito (dimensionless): 0.001015
 - iF in component Ito (dimensionless): 0.999537
 - iS in component Ito (dimensionless): 0.176283
 - ap in component Ito (dimensionless): 0.000517
 - iFp in component Ito (dimensionless): 0.999537
 - iSp in component Ito (dimensionless): 0.213308
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.804751
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966991
 - jca in component ICaL (dimensionless): 0.948493
 - ffp in component ICaL (dimensionless): 0.999868
 - fcafp in component ICaL (dimensionless): 0.999992
 - nca in component ICaL (dimensionless): 0.009459
 - xrf in component IKr (dimensionless): 0.028642
 - xrs in component IKr (dimensionless): 0.788736
 - xs1 in component IKs (dimensionless): 0.457577
 - xs2 in component IKs (dimensionless): 0.001173
 - xk1 in component IK1 (dimensionless): 0.996819
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:49:06 (86362): called boinc_finish(0)

</stderr_txt>
]]>


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