𝕏

Task 55850272

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-BASE_MID-conf_670_0
Workunit 26521775
Created 3 Jul 2024, 5:12:14 UTC
Sent 3 Jul 2024, 7:30:31 UTC
Report deadline 6 Jul 2024, 7:30:31 UTC
Received 3 Jul 2024, 20:53:30 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 38 min 25 sec
CPU time 1 hours 59 min 36 sec
Validate state Checked, but no consensus yet
Credit 0.00
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.95 MB
Peak swap size 32.60 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-BASE_MID-conf_670.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-BASE_MID-conf_670_0_r885560775_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-BASE_MID-conf_670_0_r885560775_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 101.512501
     * GNaL_b in INaL: 0.005884
     * Gto_b in Ito: 0.087554
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031840
     * GKs_b in IKs: 0.001884
     * GK1_b in IK1: 0.167203
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.237509
     * GKb_b in IKb: 0.003818
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033787
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 6678864, states[0] = -36.957768, states[40]= 0.000214


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-BASE_MID-conf_670.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-BASE_MID-conf_670_0_r885560775_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-BASE_MID-conf_670_0_r885560775_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 101.512501
     * GNaL_b in INaL: 0.005884
     * Gto_b in Ito: 0.087554
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031840
     * GKs_b in IKs: 0.001884
     * GK1_b in IK1: 0.167203
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.237509
     * GKb_b in IKb: 0.003818
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033787
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 6678864
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -36.957768 (After loading)
 - states[40]: 0.000214 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 18441755, states[0] = -86.901976, states[40]= 0.000002
Saving checkpoint... 
Iteration: 28516696, states[0] = 31.327861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39183282, states[0] = -55.007325, states[40]= 0.000050
Saving checkpoint... 
Iteration: 49549674, states[0] = 27.707376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59818739, states[0] = -86.807355, states[40]= 0.000001
Saving checkpoint... 
Iteration: 70031749, states[0] = 31.311239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80405938, states[0] = -86.959984, states[40]= 0.000002
Saving checkpoint... 
Iteration: 90705483, states[0] = -86.082568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100919408, states[0] = -86.980535, states[40]= 0.000002
Saving checkpoint... 
Iteration: 111240286, states[0] = -86.514411, states[40]= 0.000001
Saving checkpoint... 
Iteration: 121443586, states[0] = -87.001439, states[40]= 0.000002
Saving checkpoint... 
Iteration: 131615186, states[0] = -2.887645, states[40]= 0.000157
Saving checkpoint... 
Iteration: 141569798, states[0] = 19.709176, states[40]= 0.000002
Saving checkpoint... 
Iteration: 150923264, states[0] = -86.990277, states[40]= 0.000002
Saving checkpoint... 
Iteration: 159385945, states[0] = -86.956202, states[40]= 0.000002
Saving checkpoint... 
Iteration: 166151326, states[0] = -32.252184, states[40]= 0.000562
Saving checkpoint... 
Iteration: 173207608, states[0] = -86.228705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181768454, states[0] = -86.671867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 191260678, states[0] = -86.634503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 201390169, states[0] = -86.959862, states[40]= 0.000002
Saving checkpoint... 
Iteration: 210690509, states[0] = -78.202905, states[40]= 0.000003
Saving checkpoint... 
Iteration: 220963842, states[0] = -87.012542, states[40]= 0.000002
Saving checkpoint... 
Iteration: 231525742, states[0] = 31.469358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241770396, states[0] = -86.677864, states[40]= 0.000001
Saving checkpoint... 
Iteration: 251832157, states[0] = -86.869142, states[40]= 0.000002
Saving checkpoint... 
Iteration: 261571352, states[0] = 19.010126, states[40]= 0.000002
Saving checkpoint... 
Iteration: 270451399, states[0] = -87.003594, states[40]= 0.000002
Saving checkpoint... 
Iteration: 279223840, states[0] = -86.397840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288560762, states[0] = 23.161281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297722466, states[0] = -86.385908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306890906, states[0] = -86.954860, states[40]= 0.000002
Saving checkpoint... 
Iteration: 316870054, states[0] = -86.929287, states[40]= 0.000002
Saving checkpoint... 
Iteration: 326910969, states[0] = -86.972714, states[40]= 0.000002
Saving checkpoint... 
Iteration: 336487505, states[0] = -87.015537, states[40]= 0.000002
Saving checkpoint... 
Iteration: 345973149, states[0] = -87.009434, states[40]= 0.000002
Saving checkpoint... 
Iteration: 355817086, states[0] = -86.828419, states[40]= 0.000002
Saving checkpoint... 
Iteration: 366588865, states[0] = 11.225337, states[40]= 0.000017
Saving checkpoint... 
Iteration: 377342588, states[0] = -86.882135, states[40]= 0.000002
Saving checkpoint... 
Iteration: 387900710, states[0] = -86.959811, states[40]= 0.000002
Saving checkpoint... 
Iteration: 398181862, states[0] = -64.592833, states[40]= 0.000018
Saving checkpoint... 
Iteration: 408742078, states[0] = -86.517378, states[40]= 0.000001
Saving checkpoint... 
Iteration: 418919715, states[0] = -86.974200, states[40]= 0.000002
Saving checkpoint... 
Iteration: 429435771, states[0] = -86.984844, states[40]= 0.000002
Saving checkpoint... 
Iteration: 439833803, states[0] = -86.861211, states[40]= 0.000002
Saving checkpoint... 
Iteration: 449271804, states[0] = -86.671422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 459480257, states[0] = -87.005425, states[40]= 0.000002
Saving checkpoint... 
Iteration: 469008459, states[0] = 25.986463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478484679, states[0] = -87.005941, states[40]= 0.000002
Saving checkpoint... 
Iteration: 487852524, states[0] = -86.892746, states[40]= 0.000002
Saving checkpoint... 
Iteration: 497025070, states[0] = 31.486934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507303919, states[0] = -86.783461, states[40]= 0.000002
Saving checkpoint... 
Iteration: 515877671, states[0] = -86.927042, states[40]= 0.000002
Saving checkpoint... 
Iteration: 525841417, states[0] = -86.870923, states[40]= 0.000002
Saving checkpoint... 
Iteration: 535680563, states[0] = -62.787997, states[40]= 0.000023
Saving checkpoint... 
Iteration: 545766927, states[0] = -86.643561, states[40]= 0.000001
Saving checkpoint... 
Iteration: 556023788, states[0] = 31.485108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566180503, states[0] = -62.701186, states[40]= 0.000023
Saving checkpoint... 
Iteration: 576554487, states[0] = 25.379884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586423837, states[0] = -86.967163, states[40]= 0.000002
Saving checkpoint... 
Iteration: 596180146, states[0] = -62.222290, states[40]= 0.000025
Saving checkpoint... 
Iteration: 606403834, states[0] = -86.949498, states[40]= 0.000002
Saving checkpoint... 
Iteration: 616313946, states[0] = -86.804506, states[40]= 0.000002
Saving checkpoint... 
Iteration: 623332498, states[0] = -86.847367, states[40]= 0.000002
Saving checkpoint... 
Iteration: 632729971, states[0] = -86.421692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642251624, states[0] = -86.559533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 651806184, states[0] = -86.781169, states[40]= 0.000002
Saving checkpoint... 
Iteration: 661384464, states[0] = -86.926295, states[40]= 0.000002
Saving checkpoint... 
Iteration: 671370071, states[0] = -86.907810, states[40]= 0.000002
Saving checkpoint... 
Iteration: 681456279, states[0] = -86.981383, states[40]= 0.000002
Saving checkpoint... 
Iteration: 691643858, states[0] = -26.201449, states[40]= 0.000522
Saving checkpoint... 
Iteration: 700244943, states[0] = -86.516942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 710898094, states[0] = -86.937729, states[40]= 0.000002
Saving checkpoint... 
Iteration: 720821198, states[0] = -86.816181, states[40]= 0.000002
Saving checkpoint... 
Iteration: 730157506, states[0] = -37.864633, states[40]= 0.000405
Saving checkpoint... 
Iteration: 740125118, states[0] = -10.705967, states[40]= 0.000201
Saving checkpoint... 
Iteration: 747206072, states[0] = -86.153256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757864768, states[0] = -86.895212, states[40]= 0.000002
Saving checkpoint... 
Iteration: 767567435, states[0] = 20.611481, states[40]= 0.000001
Saving checkpoint... 
Iteration: 776411218, states[0] = -86.945752, states[40]= 0.000002
Saving checkpoint... 
Iteration: 786357827, states[0] = -86.883125, states[40]= 0.000002
Saving checkpoint... 
Iteration: 796566961, states[0] = 20.800292, states[40]= 0.000001
Saving checkpoint... 
Iteration: 806820401, states[0] = -86.809037, states[40]= 0.000002
Saving checkpoint... 
Iteration: 817192933, states[0] = -81.435445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 827527995, states[0] = 31.372785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837678925, states[0] = -60.599790, states[40]= 0.000030
Saving checkpoint... 
Iteration: 846384467, states[0] = -86.915085, states[40]= 0.000002
Saving checkpoint... 
Iteration: 855998963, states[0] = -86.988017, states[40]= 0.000002
Saving checkpoint... 
Iteration: 864556242, states[0] = 24.789530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873475351, states[0] = -86.978550, states[40]= 0.000002
Saving checkpoint... 
Iteration: 882344466, states[0] = -86.854888, states[40]= 0.000002
Saving checkpoint... 
Iteration: 891369622, states[0] = -86.893886, states[40]= 0.000002
Saving checkpoint... 
Iteration: 900677700, states[0] = -59.065292, states[40]= 0.000037
Saving checkpoint... 
Iteration: 910323712, states[0] = -86.810561, states[40]= 0.000002
Saving checkpoint... 
Iteration: 920318452, states[0] = -86.797377, states[40]= 0.000002
Saving checkpoint... 
Iteration: 930489167, states[0] = -86.980324, states[40]= 0.000002
Saving checkpoint... 
Iteration: 940641593, states[0] = -24.384717, states[40]= 0.000450
Saving checkpoint... 
Iteration: 949695477, states[0] = -83.782362, states[40]= 0.000001
Saving checkpoint... 
Iteration: 959111569, states[0] = -0.749753, states[40]= 0.000129
Saving checkpoint... 
Iteration: 969135118, states[0] = -19.181663, states[40]= 0.000255
Saving checkpoint... 
Iteration: 978626389, states[0] = -11.759119, states[40]= 0.000199
Saving checkpoint... 
Iteration: 988495186, states[0] = -86.978841, states[40]= 0.000002
Saving checkpoint... 
Iteration: 997710774, states[0] = -86.232048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008266646, states[0] = -86.613739, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1019560178, states[0] = 23.393052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031189178, states[0] = -75.909063, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1042062335, states[0] = 22.593482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1051941830, states[0] = -86.951058, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1061867778, states[0] = -86.881012, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1071589894, states[0] = 10.759041, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1080986726, states[0] = -86.970397, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1089799348, states[0] = -86.733992, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1098624549, states[0] = -10.197866, states[40]= 0.000200
Saving checkpoint... 
Iteration: 1107554361, states[0] = 25.435129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116273785, states[0] = -86.638883, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1125352725, states[0] = -86.854409, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1134835056, states[0] = -86.821501, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1144546134, states[0] = 27.970382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155627780, states[0] = -12.930724, states[40]= 0.000198
Saving checkpoint... 
Iteration: 1166084338, states[0] = 13.356887, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1173468991, states[0] = -86.957775, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1184571202, states[0] = 19.093804, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1195392681, states[0] = -86.902972, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1205674744, states[0] = -55.521775, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1215824545, states[0] = -86.793871, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1225969351, states[0] = -86.954754, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1236863807, states[0] = -86.864770, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1248334125, states[0] = -86.812695, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1259650435, states[0] = -31.539895, states[40]= 0.000565
Saving checkpoint... 
Iteration: 1270553774, states[0] = 25.634567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280385277, states[0] = -86.889775, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1288992261, states[0] = -86.959814, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1297605607, states[0] = 2.755837, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1306509145, states[0] = 26.632641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315917090, states[0] = -86.917984, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1325112643, states[0] = -1.402736, states[40]= 0.000137
Saving checkpoint... 
Iteration: 1333623770, states[0] = -9.531612, states[40]= 0.000199
Saving checkpoint... 
Iteration: 1343332626, states[0] = -86.803807, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1353832015, states[0] = -86.801884, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1361322658, states[0] = -86.780622, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1371836037, states[0] = -86.809062, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1382003193, states[0] = 16.882253, states[40]= 1.249623
Saving checkpoint... 
Iteration: 1392448727, states[0] = -86.934535, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1403144607, states[0] = -26.733678, states[40]= 0.000533
Saving checkpoint... 
Iteration: 1413357682, states[0] = -86.844887, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1423253165, states[0] = -86.519699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1432713884, states[0] = -86.240041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441482532, states[0] = -86.947172, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1449795020, states[0] = -86.698141, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1457612793, states[0] = -1.490187, states[40]= 0.000138
Saving checkpoint... 
Iteration: 1465594069, states[0] = 8.753543, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1474227061, states[0] = -86.347613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483384140, states[0] = -86.876187, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1493626628, states[0] = -11.915437, states[40]= 0.000198
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.825492
 - CaMKt in component CaMK (millimolar): 0.025559
 - cass in component intracellular_ions (millimolar): 0.000094
 - nai in component intracellular_ions (millimolar): 8.058625
 - nass in component intracellular_ions (millimolar): 8.058781
 - ki in component intracellular_ions (millimolar): 143.288295
 - kss in component intracellular_ions (millimolar): 143.288256
 - cansr in component intracellular_ions (millimolar): 2.085118
 - cajsr in component intracellular_ions (millimolar): 2.022517
 - cai in component intracellular_ions (millimolar): 0.000097
 - m in component INa (dimensionless): 0.008164
 - hf in component INa (dimensionless): 0.660472
 - hs in component INa (dimensionless): 0.660442
 - j in component INa (dimensionless): 0.660272
 - hsp in component INa (dimensionless): 0.412471
 - jp in component INa (dimensionless): 0.660150
 - mL in component INaL (dimensionless): 0.000230
 - hL in component INaL (dimensionless): 0.456789
 - hLp in component INaL (dimensionless): 0.222862
 - a in component Ito (dimensionless): 0.001075
 - iF in component Ito (dimensionless): 0.999464
 - iS in component Ito (dimensionless): 0.534436
 - ap in component Ito (dimensionless): 0.000548
 - iFp in component Ito (dimensionless): 0.999464
 - iSp in component Ito (dimensionless): 0.578226
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.877195
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999617
 - jca in component ICaL (dimensionless): 0.999940
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003992
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.507633
 - xs1 in component IKs (dimensionless): 0.333892
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997025
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
13:53:16 (85582): called boinc_finish(0)

</stderr_txt>
]]>


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