𝕏

Task 55849925

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-Coppini_1000-conf_668_1
Workunit 26521601
Created 3 Jul 2024, 5:12:09 UTC
Sent 3 Jul 2024, 7:27:00 UTC
Report deadline 6 Jul 2024, 7:27:00 UTC
Received 6 Jul 2024, 6:41:45 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232764
Run time 2 hours 1 min 43 sec
CPU time 2 hours 1 min 43 sec
Validate state Valid
Credit 46.08
Device peak FLOPS 3.62 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.70 MB
Peak swap size 5.31 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Coppini_1000-conf_668.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Coppini_1000-conf_668_1_r438174474_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Coppini_1000-conf_668_1_r438174474_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.232187
     * GNaL_b in INaL: 0.006146
     * Gto_b in Ito: 0.084915
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032075
     * GKs_b in IKs: 0.001887
     * GK1_b in IK1: 0.161656
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.434534
     * GKb_b in IKb: 0.003814
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030195
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11588318, states[0] = -2.984510, states[40]= 0.004012
Saving checkpoint... 
Iteration: 23124980, states[0] = -36.996731, states[40]= 0.000490
Saving checkpoint... 
Iteration: 34294144, states[0] = -94.771761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45200989, states[0] = -94.490827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56366293, states[0] = -94.848713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67453160, states[0] = -94.893308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77896073, states[0] = -94.866637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89147942, states[0] = -59.546967, states[40]= 0.000021
Saving checkpoint... 
Iteration: 100179229, states[0] = -94.011085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111233665, states[0] = -94.610636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122100570, states[0] = -12.388391, states[40]= 0.002156
Saving checkpoint... 
Iteration: 133010426, states[0] = 27.686964, states[40]= 0.042520
Saving checkpoint... 
Iteration: 143746370, states[0] = -94.649445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154335656, states[0] = -94.814571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165699555, states[0] = -94.474651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176853732, states[0] = -94.832508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187809031, states[0] = -94.780395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198520700, states[0] = 26.974402, states[40]= 0.002353
Saving checkpoint... 
Iteration: 209544865, states[0] = 19.559060, states[40]= 0.002243
Saving checkpoint... 
Iteration: 220272970, states[0] = -94.715720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230872312, states[0] = -94.847618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241528672, states[0] = 25.075470, states[40]= 0.001449
Saving checkpoint... 
Iteration: 253222261, states[0] = -94.568893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264153156, states[0] = -65.400335, states[40]= 0.000008
Saving checkpoint... 
Iteration: 275274695, states[0] = -94.719160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286520263, states[0] = 27.050360, states[40]= 0.002543
Saving checkpoint... 
Iteration: 297030495, states[0] = 24.535129, states[40]= 0.001484
Saving checkpoint... 
Iteration: 308330385, states[0] = -94.807710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320109335, states[0] = -20.915961, states[40]= 0.001263
Saving checkpoint... 
Iteration: 332224857, states[0] = -94.578125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343493054, states[0] = -94.899497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354799478, states[0] = -94.764904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365812658, states[0] = -94.784759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377159185, states[0] = -73.300704, states[40]= 0.000002
Saving checkpoint... 
Iteration: 388293964, states[0] = -94.755561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399298925, states[0] = -94.763820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409964661, states[0] = -94.892005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421101615, states[0] = -13.376200, states[40]= 0.001979
Saving checkpoint... 
Iteration: 432277370, states[0] = -94.724094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443166689, states[0] = -85.128648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454299033, states[0] = -94.763766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465364822, states[0] = -94.840747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476353032, states[0] = -94.830493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487896596, states[0] = -94.862747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499195259, states[0] = -94.451273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510448520, states[0] = -94.886423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521384980, states[0] = -94.855347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532791700, states[0] = -94.751016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543240359, states[0] = -94.629403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554684017, states[0] = -94.310423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566689133, states[0] = -94.406036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577687063, states[0] = -94.379349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588639808, states[0] = -50.691593, states[40]= 0.000084
Saving checkpoint... 
Iteration: 599412787, states[0] = -94.871078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609797210, states[0] = -94.760120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620908640, states[0] = -94.868872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631697999, states[0] = -94.464967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643282526, states[0] = -94.733547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654365384, states[0] = -94.840417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665114246, states[0] = -25.597654, states[40]= 0.001185
Saving checkpoint... 
Iteration: 676244540, states[0] = -94.641504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687243294, states[0] = -94.637745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698238660, states[0] = -94.623442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709852879, states[0] = -94.829380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721282904, states[0] = -94.733956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732188962, states[0] = -94.403487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743136155, states[0] = -46.878421, states[40]= 0.000147
Saving checkpoint... 
Iteration: 754126267, states[0] = -37.011612, states[40]= 0.000529
Saving checkpoint... 
Iteration: 765030586, states[0] = 24.508015, states[40]= 0.001487
Saving checkpoint... 
Iteration: 776200977, states[0] = -94.478561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787384212, states[0] = -94.853731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799151866, states[0] = -63.866832, states[40]= 0.000010
Saving checkpoint... 
Iteration: 810058009, states[0] = 14.371676, states[40]= 0.003276
Saving checkpoint... 
Iteration: 821123702, states[0] = -34.550429, states[40]= 0.000689
Saving checkpoint... 
Iteration: 832456135, states[0] = -94.887631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842858131, states[0] = -94.833536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854040074, states[0] = 21.319754, states[40]= 0.001931
Saving checkpoint... 
Iteration: 864689220, states[0] = -94.405667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876099279, states[0] = -11.113259, states[40]= 0.002409
Saving checkpoint... 
Iteration: 887343618, states[0] = -94.819688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897612202, states[0] = -23.657973, states[40]= 0.001216
Saving checkpoint... 
Iteration: 909139320, states[0] = -50.176780, states[40]= 0.000091
Saving checkpoint... 
Iteration: 919897897, states[0] = -94.861714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930545201, states[0] = 19.434595, states[40]= 0.002267
Saving checkpoint... 
Iteration: 940758193, states[0] = -94.677931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952320490, states[0] = -94.792877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963095936, states[0] = -7.994123, states[40]= 0.003096
Saving checkpoint... 
Iteration: 974334976, states[0] = -94.810155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985629907, states[0] = -40.561546, states[40]= 0.000345
Saving checkpoint... 
Iteration: 996726631, states[0] = -94.581731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007559087, states[0] = 13.918177, states[40]= 0.003364
Saving checkpoint... 
Iteration: 1018637069, states[0] = -47.824159, states[40]= 0.000128
Saving checkpoint... 
Iteration: 1029915804, states[0] = -94.870776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040901433, states[0] = -94.863231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051661650, states[0] = -77.005428, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1062743022, states[0] = -94.635352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073873671, states[0] = -94.845106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085060278, states[0] = 13.410985, states[40]= 0.003461
Saving checkpoint... 
Iteration: 1096672448, states[0] = -91.731056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108411162, states[0] = -94.868146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119706416, states[0] = -94.501386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130963142, states[0] = -94.888564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142017701, states[0] = 27.414154, states[40]= 0.004506
Saving checkpoint... 
Iteration: 1152764195, states[0] = -94.691841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164057852, states[0] = 14.437851, states[40]= 0.003263
Saving checkpoint... 
Iteration: 1175134976, states[0] = -45.662686, states[40]= 0.000175
Saving checkpoint... 
Iteration: 1185571003, states[0] = 8.485511, states[40]= 0.004238
Saving checkpoint... 
Iteration: 1196665702, states[0] = -83.558488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207417720, states[0] = -94.870959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218520689, states[0] = 26.978215, states[40]= 0.002359
Saving checkpoint... 
Iteration: 1229318005, states[0] = -94.788466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239463620, states[0] = -94.888256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249587414, states[0] = -1.117198, states[40]= 0.004361
Saving checkpoint... 
Iteration: 1260154865, states[0] = -67.489084, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1271317106, states[0] = -94.787091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282195642, states[0] = -94.450050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293154791, states[0] = -67.396048, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1304128007, states[0] = -38.696629, states[40]= 0.000435
Saving checkpoint... 
Iteration: 1315300048, states[0] = -94.761816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326367507, states[0] = -94.839324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337671934, states[0] = -91.354983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349044922, states[0] = 19.539798, states[40]= 0.002248
Saving checkpoint... 
Iteration: 1360101352, states[0] = -13.116270, states[40]= 0.002024
Saving checkpoint... 
Iteration: 1371295365, states[0] = -94.753848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382436648, states[0] = -94.878420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393625542, states[0] = -36.310761, states[40]= 0.000572
Saving checkpoint... 
Iteration: 1405605004, states[0] = -16.696249, states[40]= 0.001524
Saving checkpoint... 
Iteration: 1417146771, states[0] = -58.133093, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1428229897, states[0] = -94.591407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439251581, states[0] = -94.658364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450063865, states[0] = 11.841861, states[40]= 0.003746
Saving checkpoint... 
Iteration: 1460970913, states[0] = -94.889425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472242778, states[0] = -94.632897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483457599, states[0] = -94.885397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494463727, states[0] = -94.887230, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.772033
 - CaMKt in component CaMK (millimolar): 0.012877
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.750454
 - nass in component intracellular_ions (millimolar): 6.750552
 - ki in component intracellular_ions (millimolar): 145.126844
 - kss in component intracellular_ions (millimolar): 145.126823
 - cansr in component intracellular_ions (millimolar): 1.678181
 - cajsr in component intracellular_ions (millimolar): 1.636371
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003666
 - hf in component INa (dimensionless): 0.877730
 - hs in component INa (dimensionless): 0.877722
 - j in component INa (dimensionless): 0.877669
 - hsp in component INa (dimensionless): 0.721544
 - jp in component INa (dimensionless): 0.877633
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.703682
 - hLp in component INaL (dimensionless): 0.440421
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.610627
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.681317
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.915689
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999832
 - jca in component ICaL (dimensionless): 0.999972
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003124
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.366153
 - xs1 in component IKs (dimensionless): 0.268276
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997371
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:41:15 (17124): called boinc_finish(0)

</stderr_txt>
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