𝕏

Task 55846327

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-Coppini_5000-conf_47_0
Workunit 26519803
Created 3 Jul 2024, 5:10:15 UTC
Sent 3 Jul 2024, 7:10:53 UTC
Report deadline 6 Jul 2024, 7:10:53 UTC
Received 3 Jul 2024, 22:34:35 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230398
Run time 2 hours 5 min 28 sec
CPU time 2 hours 4 min 13 sec
Validate state Valid
Credit 42.12
Device peak FLOPS 3.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.54 MB
Peak swap size 4.10 GB
Peak disk usage 1.56 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Coppini_5000-conf_47.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Coppini_5000-conf_47_0_r1493791468_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Coppini_5000-conf_47_0_r1493791468_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.962040
     * GNaL_b in INaL: 0.005752
     * Gto_b in Ito: 0.080825
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032127
     * GKs_b in IKs: 0.001900
     * GK1_b in IK1: 0.162259
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.757733
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029259
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12104647, states[0] = -94.646968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24234136, states[0] = -94.574199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36432585, states[0] = -94.536664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48574938, states[0] = -94.519567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60673829, states[0] = -94.505424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72793421, states[0] = -94.271054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84923897, states[0] = -94.473606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97105561, states[0] = -94.470955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109210827, states[0] = -94.471262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121284453, states[0] = -94.475171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133368454, states[0] = -94.481099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145488943, states[0] = -94.445270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157672503, states[0] = -58.364662, states[40]= 0.000025
Saving checkpoint... 
Iteration: 169844878, states[0] = -94.459093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181436418, states[0] = -94.467356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193502211, states[0] = -94.475192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205641060, states[0] = -94.471582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217813002, states[0] = -94.286432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229891541, states[0] = -94.457232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242079210, states[0] = -94.459059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254204000, states[0] = -94.462425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266401904, states[0] = -94.466513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278609085, states[0] = -94.471979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290702809, states[0] = -94.474511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302865243, states[0] = -94.360462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315028212, states[0] = 26.186085, states[40]= 0.001977
Saving checkpoint... 
Iteration: 327237336, states[0] = -94.457623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339373986, states[0] = -94.460381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351541964, states[0] = -94.464168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363653040, states[0] = -94.470895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375891572, states[0] = -94.475761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387997089, states[0] = -94.444264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400118014, states[0] = -12.499320, states[40]= 0.002045
Saving checkpoint... 
Iteration: 412252358, states[0] = -94.457434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424304774, states[0] = -94.460968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436447779, states[0] = -94.465475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448477086, states[0] = -94.474358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460550584, states[0] = -94.458235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472695490, states[0] = -85.478156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484704421, states[0] = -94.457682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496831615, states[0] = -94.460649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508990607, states[0] = -94.464774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521160421, states[0] = -94.470621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533267107, states[0] = -94.475872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545419119, states[0] = -94.406795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557618535, states[0] = -12.927865, states[40]= 0.001974
Saving checkpoint... 
Iteration: 569664725, states[0] = -94.457885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581735537, states[0] = -94.461589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593945359, states[0] = -94.465404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606042788, states[0] = -94.472974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618201961, states[0] = -94.474150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630290043, states[0] = -94.238544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642457984, states[0] = -94.456141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654478723, states[0] = -94.459216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666648550, states[0] = -94.462541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678773605, states[0] = -94.468297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690973976, states[0] = -94.474250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703129311, states[0] = -94.469358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715240427, states[0] = -94.095164, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Coppini_5000-conf_47.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Coppini_5000-conf_47_0_r1493791468_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Coppini_5000-conf_47_0_r1493791468_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.962040
     * GNaL_b in INaL: 0.005752
     * Gto_b in Ito: 0.080825
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032127
     * GKs_b in IKs: 0.001900
     * GK1_b in IK1: 0.162259
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.757733
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029259
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 715240427
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.095164 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 727037514, states[0] = -94.458696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739327085, states[0] = -94.460529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751582084, states[0] = -94.463330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763869760, states[0] = -94.466521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776082933, states[0] = -94.472039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788476708, states[0] = -94.474134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800695379, states[0] = -94.473748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812982788, states[0] = -94.438922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825240404, states[0] = -94.095009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837430847, states[0] = -94.456146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849736722, states[0] = -94.457230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862068026, states[0] = -94.458373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874241354, states[0] = -94.461328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886435524, states[0] = -94.465361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898695853, states[0] = -94.469653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910949701, states[0] = -94.474529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923225279, states[0] = -94.474753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935585845, states[0] = -94.464029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947960024, states[0] = -94.429336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960223217, states[0] = -94.028447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972434546, states[0] = -94.456036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984635119, states[0] = -94.457807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996863287, states[0] = -94.460006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009166859, states[0] = -94.462089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021504831, states[0] = -94.464220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033710971, states[0] = -94.469263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045923305, states[0] = -94.474862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058178950, states[0] = -94.472763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070336411, states[0] = -94.323347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082439690, states[0] = -94.455936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094649087, states[0] = -94.457637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106941568, states[0] = -94.459225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119219365, states[0] = -94.461407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131431947, states[0] = -94.465253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143678420, states[0] = -94.469838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155986123, states[0] = -94.473713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168197344, states[0] = -94.473587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180399956, states[0] = -94.392386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192741873, states[0] = -94.099852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205076824, states[0] = 11.577426, states[40]= 0.004352
Saving checkpoint... 
Iteration: 1217349982, states[0] = -94.456318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229623901, states[0] = -94.457721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242030051, states[0] = -94.458408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254321928, states[0] = -94.460233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266587278, states[0] = -94.462914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278807924, states[0] = -94.467260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291029257, states[0] = -94.472785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303197963, states[0] = -94.473523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315385629, states[0] = -94.380106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327548976, states[0] = 21.194163, states[40]= 0.002779
Saving checkpoint... 
Iteration: 1339675523, states[0] = -94.457294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351885324, states[0] = -94.459561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363991560, states[0] = -94.464184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376136316, states[0] = -94.470537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388318494, states[0] = -94.475582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400438245, states[0] = -94.417936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412552386, states[0] = 20.190517, states[40]= 0.002985
Saving checkpoint... 
Iteration: 1424742696, states[0] = -94.456806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436936692, states[0] = -94.459045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449129915, states[0] = -94.462244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461320885, states[0] = -94.466904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473510649, states[0] = -94.473029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485631131, states[0] = -94.469003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497730187, states[0] = -94.057673, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.331335
 - CaMKt in component CaMK (millimolar): 0.001118
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.292542
 - nass in component intracellular_ions (millimolar): 6.292628
 - ki in component intracellular_ions (millimolar): 145.633720
 - kss in component intracellular_ions (millimolar): 145.633710
 - cansr in component intracellular_ions (millimolar): 1.562714
 - cajsr in component intracellular_ions (millimolar): 1.562740
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.003833
 - hf in component INa (dimensionless): 0.869742
 - hs in component INa (dimensionless): 0.869742
 - j in component INa (dimensionless): 0.869743
 - hsp in component INa (dimensionless): 0.706812
 - jp in component INa (dimensionless): 0.869744
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.713869
 - hLp in component INaL (dimensionless): 0.521482
 - a in component Ito (dimensionless): 0.000648
 - iF in component Ito (dimensionless): 0.999856
 - iS in component Ito (dimensionless): 0.997764
 - ap in component Ito (dimensionless): 0.000330
 - iFp in component Ito (dimensionless): 0.999856
 - iSp in component Ito (dimensionless): 0.999259
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998878
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002970
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001785
 - xs1 in component IKs (dimensionless): 0.022555
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997483
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:33:23 (71366): called boinc_finish(0)

</stderr_txt>
]]>


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