𝕏

Task 55845703

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pueyo_APDR-conf_743_0
Workunit 26519491
Created 3 Jul 2024, 5:09:54 UTC
Sent 3 Jul 2024, 7:04:01 UTC
Report deadline 6 Jul 2024, 16:40:01 UTC
Received 6 Jul 2024, 7:33:08 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215802
Run time 2 hours 54 min 53 sec
CPU time 2 hours 49 min 47 sec
Validate state Valid
Credit 65.04
Device peak FLOPS 3.11 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.18 MB
Peak swap size 6.23 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pueyo_APDR-conf_743.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pueyo_APDR-conf_743_0_r879910341_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pueyo_APDR-conf_743_0_r879910341_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.116743
     * GNaL_b in INaL: 0.006000
     * Gto_b in Ito: 0.087567
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031596
     * GKs_b in IKs: 0.001970
     * GK1_b in IK1: 0.167871
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 69.920120
     * GKb_b in IKb: 0.003783
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032035
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13240242, states[0] = -94.977498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26355790, states[0] = -95.039306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39600820, states[0] = -20.616798, states[40]= 0.000934
Saving checkpoint... 
Iteration: 52771582, states[0] = -94.954986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65876288, states[0] = -95.015020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79108954, states[0] = -27.043565, states[40]= 0.000623
Saving checkpoint... 
Iteration: 92386428, states[0] = -95.011426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105191369, states[0] = -94.814246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118228012, states[0] = -94.881662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131133417, states[0] = -50.680760, states[40]= 0.000026
Saving checkpoint... 
Iteration: 144469748, states[0] = -95.026082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157468364, states[0] = -95.025459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170462944, states[0] = -95.024313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183747638, states[0] = -94.907714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196864421, states[0] = -94.997580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210014606, states[0] = 21.999260, states[40]= 0.019426
Saving checkpoint... 
Iteration: 223349571, states[0] = -94.990863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236625330, states[0] = -42.132057, states[40]= 0.000097
Saving checkpoint... 
Iteration: 249863746, states[0] = -94.997053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263110759, states[0] = -28.197705, states[40]= 0.000568
Saving checkpoint... 
Iteration: 276209474, states[0] = -94.846565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289590195, states[0] = -9.384022, states[40]= 0.002448
Saving checkpoint... 
Iteration: 302850449, states[0] = -94.991111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316080366, states[0] = -2.187571, states[40]= 0.003899
Saving checkpoint... 
Iteration: 329381898, states[0] = -95.003841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342469315, states[0] = -95.024626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355632639, states[0] = -49.704688, states[40]= 0.000030
Saving checkpoint... 
Iteration: 368832539, states[0] = -94.981878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382002428, states[0] = 40.774182, states[40]= 0.117795
Saving checkpoint... 
Iteration: 395282983, states[0] = -94.946138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408396802, states[0] = -95.008624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421566326, states[0] = 5.196009, states[40]= 0.004693
Saving checkpoint... 
Iteration: 434851873, states[0] = -94.991674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447965378, states[0] = -95.023933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460962236, states[0] = -95.023415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473971590, states[0] = -95.024879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487273606, states[0] = -94.937069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500450103, states[0] = -95.021275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513698972, states[0] = -94.825886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527096172, states[0] = -14.664755, states[40]= 0.001506
Saving checkpoint... 
Iteration: 540391739, states[0] = -95.006964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553797081, states[0] = -94.958052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567056019, states[0] = 9.557037, states[40]= 0.004853
Saving checkpoint... 
Iteration: 580255745, states[0] = -94.917264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593460332, states[0] = -95.023009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606459559, states[0] = -95.022870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619710234, states[0] = -94.847726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632897707, states[0] = -95.008743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645987937, states[0] = -95.027045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659315194, states[0] = -94.971123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672477068, states[0] = -95.025549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685608501, states[0] = -26.095472, states[40]= 0.000669
Saving checkpoint... 
Iteration: 698596238, states[0] = -14.725129, states[40]= 0.001498
Saving checkpoint... 
Iteration: 711806412, states[0] = -94.965011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724992184, states[0] = -95.027529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738157358, states[0] = -82.274851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751270001, states[0] = -94.933190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764638312, states[0] = -55.877667, states[40]= 0.000011
Saving checkpoint... 
Iteration: 777724557, states[0] = -94.872803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790967729, states[0] = -95.024072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804288268, states[0] = -94.950568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817456260, states[0] = -95.022162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830568115, states[0] = 4.372741, states[40]= 0.004643
Saving checkpoint... 
Iteration: 843780873, states[0] = -94.943880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856649400, states[0] = -69.362979, states[40]= 0.000001
Saving checkpoint... 
Iteration: 869991577, states[0] = -95.027355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883033218, states[0] = 17.796616, states[40]= 0.005566
Saving checkpoint... 
Iteration: 896357668, states[0] = -94.993970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909656380, states[0] = -80.530228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922865892, states[0] = -94.997417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936042236, states[0] = 14.756489, states[40]= 0.005068
Saving checkpoint... 
Iteration: 949516781, states[0] = 21.690319, states[40]= 0.013614
Saving checkpoint... 
Iteration: 962784141, states[0] = -94.946805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975928428, states[0] = -95.016527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988958722, states[0] = -95.022469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002438779, states[0] = -95.018734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015935654, states[0] = -95.018076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029431546, states[0] = -95.017184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042446875, states[0] = -95.020303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055809080, states[0] = -94.966679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069056154, states[0] = 9.503310, states[40]= 0.004852
Saving checkpoint... 
Iteration: 1082149249, states[0] = -69.152080, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1095483623, states[0] = -95.026172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108494783, states[0] = -95.027587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121751519, states[0] = -94.911670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134873380, states[0] = -95.000201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148044580, states[0] = 13.909602, states[40]= 0.005005
Saving checkpoint... 
Iteration: 1161414883, states[0] = -95.013148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174602091, states[0] = -20.146160, states[40]= 0.000964
Saving checkpoint... 
Iteration: 1187548784, states[0] = 12.353070, states[40]= 0.004930
Saving checkpoint... 
Iteration: 1200866175, states[0] = -94.997343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213914738, states[0] = -95.013075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227118990, states[0] = -35.935061, states[40]= 0.000236
Saving checkpoint... 
Iteration: 1240371139, states[0] = -94.999275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253548457, states[0] = 12.475794, states[40]= 0.004934
Saving checkpoint... 
Iteration: 1266859724, states[0] = -94.994610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280142825, states[0] = -61.016300, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1293421825, states[0] = -95.014777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306629852, states[0] = -46.758310, states[40]= 0.000048
Saving checkpoint... 
Iteration: 1319674763, states[0] = -94.666130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332093226, states[0] = -12.003177, states[40]= 0.001935
Saving checkpoint... 
Iteration: 1344821482, states[0] = -94.974693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358091729, states[0] = -10.690346, states[40]= 0.002183
Saving checkpoint... 
Iteration: 1371211655, states[0] = -94.849849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384517073, states[0] = 21.646248, states[40]= 0.013066
Saving checkpoint... 
Iteration: 1397220376, states[0] = -94.865351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410603387, states[0] = -21.349806, states[40]= 0.000893
Saving checkpoint... 
Iteration: 1423941797, states[0] = -95.019057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437237043, states[0] = -94.891761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450412355, states[0] = -95.012297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463537555, states[0] = 16.385477, states[40]= 0.005263
Saving checkpoint... 
Iteration: 1476744092, states[0] = -94.901683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489870654, states[0] = -94.998918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503066880, states[0] = -0.750442, states[40]= 0.004503
Saving checkpoint... 
Iteration: 1516236533, states[0] = 14.974722, states[40]= 0.006236
Saving checkpoint... 
Iteration: 1529061420, states[0] = -95.240664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541789135, states[0] = -23.983718, states[40]= 0.000776
Saving checkpoint... 
Iteration: 1554864439, states[0] = -95.259051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567837689, states[0] = 13.974595, states[40]= 0.006143
Saving checkpoint... 
Iteration: 1580187539, states[0] = -22.996088, states[40]= 0.000835
Saving checkpoint... 
Iteration: 1593346663, states[0] = 9.545462, states[40]= 0.005682
Saving checkpoint... 
Iteration: 1606519940, states[0] = 20.806324, states[40]= 0.010793
Saving checkpoint... 
Iteration: 1619682269, states[0] = -95.284808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632910890, states[0] = 23.258033, states[40]= 0.043597
Saving checkpoint... 
Iteration: 1646045340, states[0] = -95.251357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659041382, states[0] = 12.115727, states[40]= 0.005919
Saving checkpoint... 
Iteration: 1672141697, states[0] = -95.247503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1685477443, states[0] = -12.458134, states[40]= 0.002107
Saving checkpoint... 
Iteration: 1698806996, states[0] = -95.197790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1712003848, states[0] = -95.192269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725179495, states[0] = -95.142376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1738339958, states[0] = -91.739769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1751539113, states[0] = -90.876430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1764601586, states[0] = 47.662298, states[40]= 0.055827
Saving checkpoint... 
Iteration: 1777743748, states[0] = -95.250058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790869285, states[0] = -95.117333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803901042, states[0] = -95.062487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1817156263, states[0] = -85.834123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1830322020, states[0] = -95.002130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843487574, states[0] = -95.044791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856485174, states[0] = -95.038483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869746345, states[0] = -94.913112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882983187, states[0] = -95.031284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896190530, states[0] = -94.810939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909461335, states[0] = -95.024855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922679414, states[0] = -94.762879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935806181, states[0] = -94.965169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949030893, states[0] = 18.492842, states[40]= 0.005802
Saving checkpoint... 
Iteration: 1962305981, states[0] = -94.964345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975348483, states[0] = -94.989348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988157075, states[0] = -81.802899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001333097, states[0] = -94.981191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2014537843, states[0] = 16.286502, states[40]= 0.005248
Saving checkpoint... 
Iteration: 2027624138, states[0] = -40.941686, states[40]= 0.000116
Saving checkpoint... 
Iteration: 2040546429, states[0] = 13.229862, states[40]= 0.004967
Saving checkpoint... 
Iteration: 2053697897, states[0] = -94.822620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066866346, states[0] = -94.996787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079956854, states[0] = -95.021364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093219685, states[0] = -94.863637, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.903353
 - CaMKt in component CaMK (millimolar): 0.007128
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.611089
 - nass in component intracellular_ions (millimolar): 6.611150
 - ki in component intracellular_ions (millimolar): 145.364383
 - kss in component intracellular_ions (millimolar): 145.364363
 - cansr in component intracellular_ions (millimolar): 1.319755
 - cajsr in component intracellular_ions (millimolar): 1.281455
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003618
 - hf in component INa (dimensionless): 0.880027
 - hs in component INa (dimensionless): 0.880022
 - j in component INa (dimensionless): 0.879994
 - hsp in component INa (dimensionless): 0.725880
 - jp in component INa (dimensionless): 0.879974
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709584
 - hLp in component INaL (dimensionless): 0.450950
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.619454
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.694072
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934414
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999882
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001629
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330668
 - xs1 in component IKs (dimensionless): 0.244170
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:32:55 (97404): called boinc_finish(0)

</stderr_txt>
]]>


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