𝕏

Task 55845696

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pueyo_APDR-conf_343_1
Workunit 26519487
Created 3 Jul 2024, 5:09:54 UTC
Sent 3 Jul 2024, 7:04:01 UTC
Report deadline 6 Jul 2024, 16:40:01 UTC
Received 6 Jul 2024, 7:00:26 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215802
Run time 2 hours 55 min 8 sec
CPU time 2 hours 51 min 26 sec
Validate state Valid
Credit 62.08
Device peak FLOPS 3.11 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.19 MB
Peak swap size 6.23 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pueyo_APDR-conf_343.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pueyo_APDR-conf_343_1_r176764917_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pueyo_APDR-conf_343_1_r176764917_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.985475
     * GNaL_b in INaL: 0.006143
     * Gto_b in Ito: 0.085364
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032198
     * GKs_b in IKs: 0.001889
     * GK1_b in IK1: 0.166350
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.767025
     * GKb_b in IKb: 0.003793
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036874
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13123023, states[0] = -46.784065, states[40]= 0.000044
Saving checkpoint... 
Iteration: 26306154, states[0] = -95.075332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39424190, states[0] = -95.105724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52629047, states[0] = -49.415000, states[40]= 0.000031
Saving checkpoint... 
Iteration: 65782406, states[0] = -95.018753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78948509, states[0] = -95.086958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91999812, states[0] = -95.091098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105045672, states[0] = 13.329214, states[40]= 0.005060
Saving checkpoint... 
Iteration: 118045353, states[0] = 13.473534, states[40]= 0.005067
Saving checkpoint... 
Iteration: 131259128, states[0] = -94.982180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144575021, states[0] = 0.511085, states[40]= 0.004306
Saving checkpoint... 
Iteration: 157773736, states[0] = -94.996374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170873453, states[0] = -95.057700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183887573, states[0] = -95.062322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197126783, states[0] = -45.323875, states[40]= 0.000058
Saving checkpoint... 
Iteration: 210110226, states[0] = -28.882796, states[40]= 0.000519
Saving checkpoint... 
Iteration: 223182888, states[0] = -94.850207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236401962, states[0] = -95.066248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249614990, states[0] = -33.444598, states[40]= 0.000316
Saving checkpoint... 
Iteration: 262947104, states[0] = -95.076513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276152340, states[0] = -77.321903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289319998, states[0] = -95.031398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302498648, states[0] = -95.083989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315818830, states[0] = -95.030650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329146063, states[0] = -67.708961, states[40]= 0.000001
Saving checkpoint... 
Iteration: 342294426, states[0] = -95.013489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355423533, states[0] = -95.071558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368832758, states[0] = -95.038686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382097168, states[0] = -16.476820, states[40]= 0.001278
Saving checkpoint... 
Iteration: 395333192, states[0] = -95.038903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408576826, states[0] = -0.469789, states[40]= 0.004176
Saving checkpoint... 
Iteration: 421864697, states[0] = -95.053527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435115480, states[0] = -33.914127, states[40]= 0.000298
Saving checkpoint... 
Iteration: 448497061, states[0] = -95.083703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461671733, states[0] = -94.687282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475031071, states[0] = 18.457265, states[40]= 0.005957
Saving checkpoint... 
Iteration: 488023668, states[0] = 20.475413, states[40]= 0.007608
Saving checkpoint... 
Iteration: 500533042, states[0] = 17.842636, states[40]= 0.005737
Saving checkpoint... 
Iteration: 513731064, states[0] = -94.942858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526981707, states[0] = -95.081750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540180299, states[0] = -94.839304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553234563, states[0] = -94.948022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566383150, states[0] = -95.060177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579594299, states[0] = -13.792811, states[40]= 0.001639
Saving checkpoint... 
Iteration: 592765323, states[0] = -94.986516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605927829, states[0] = -95.072365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619197066, states[0] = -94.882828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632277521, states[0] = -94.998705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645287642, states[0] = -95.007736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658393672, states[0] = -95.063470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671567323, states[0] = 4.469921, states[40]= 0.004674
Saving checkpoint... 
Iteration: 684652280, states[0] = -77.214222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697759383, states[0] = -94.979925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710756462, states[0] = -94.976559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723988861, states[0] = -95.082549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737177923, states[0] = -94.823770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750250362, states[0] = -94.969189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763440570, states[0] = -95.074915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776651051, states[0] = -75.153134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789711699, states[0] = -94.910634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802848767, states[0] = -95.046440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816067616, states[0] = 4.331765, states[40]= 0.004665
Saving checkpoint... 
Iteration: 829218398, states[0] = -94.922343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842473743, states[0] = -95.080452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855577772, states[0] = -1.027848, states[40]= 0.004096
Saving checkpoint... 
Iteration: 868590145, states[0] = -10.058231, states[40]= 0.002317
Saving checkpoint... 
Iteration: 881721347, states[0] = -94.927258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894865422, states[0] = -95.053519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907882482, states[0] = -95.059740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921004786, states[0] = 29.089828, states[40]= 0.149574
Saving checkpoint... 
Iteration: 934124674, states[0] = -43.087854, states[40]= 0.000082
Saving checkpoint... 
Iteration: 947227948, states[0] = -94.937812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960415428, states[0] = -95.069247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973597778, states[0] = -17.052472, states[40]= 0.001215
Saving checkpoint... 
Iteration: 986749201, states[0] = -94.967590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999976835, states[0] = -95.080791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013251800, states[0] = -94.970797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026391793, states[0] = -95.062666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039531595, states[0] = 18.296708, states[40]= 0.005894
Saving checkpoint... 
Iteration: 1052648008, states[0] = -70.446537, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1065836151, states[0] = -95.040055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078745957, states[0] = -94.963386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091894851, states[0] = -95.063555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104912894, states[0] = -95.068522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118018075, states[0] = 21.632276, states[40]= 0.011956
Saving checkpoint... 
Iteration: 1131096163, states[0] = -15.530505, states[40]= 0.001392
Saving checkpoint... 
Iteration: 1144230287, states[0] = -94.941285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157287171, states[0] = -95.007016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170504978, states[0] = 28.544891, states[40]= 0.147134
Saving checkpoint... 
Iteration: 1183640895, states[0] = -61.131267, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1196724074, states[0] = -94.931518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209765610, states[0] = -94.986435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222637264, states[0] = -56.873555, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1235607119, states[0] = -25.911578, states[40]= 0.000661
Saving checkpoint... 
Iteration: 1248676141, states[0] = -94.804568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261956399, states[0] = -95.077485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275329897, states[0] = -95.036547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288558351, states[0] = 8.421050, states[40]= 0.004864
Saving checkpoint... 
Iteration: 1301783830, states[0] = -95.004030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315004967, states[0] = 28.574799, states[40]= 0.147287
Saving checkpoint... 
Iteration: 1328119194, states[0] = -37.543166, states[40]= 0.000184
Saving checkpoint... 
Iteration: 1341538263, states[0] = 16.096622, states[40]= 0.005342
Saving checkpoint... 
Iteration: 1354824889, states[0] = -95.033641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368018090, states[0] = 21.629654, states[40]= 0.011935
Saving checkpoint... 
Iteration: 1381366141, states[0] = -95.053499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394643571, states[0] = -64.433340, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1408010931, states[0] = 22.896149, states[40]= 0.042946
Saving checkpoint... 
Iteration: 1421178610, states[0] = -94.828646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434375767, states[0] = -95.057079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447489988, states[0] = -95.082238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460613208, states[0] = -31.723086, states[40]= 0.000387
Saving checkpoint... 
Iteration: 1473786017, states[0] = -95.005829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486930782, states[0] = -95.072457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500150419, states[0] = -87.483663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513141983, states[0] = -95.263879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526201765, states[0] = -38.002854, states[40]= 0.000173
Saving checkpoint... 
Iteration: 1539374852, states[0] = -9.525949, states[40]= 0.002738
Saving checkpoint... 
Iteration: 1552451512, states[0] = -95.305238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565464658, states[0] = -1.245064, states[40]= 0.004580
Saving checkpoint... 
Iteration: 1578550376, states[0] = -95.311951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591617486, states[0] = -58.882580, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1604778949, states[0] = -14.682662, states[40]= 0.001703
Saving checkpoint... 
Iteration: 1617800429, states[0] = -95.246789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630959407, states[0] = -95.151593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644115479, states[0] = -56.524959, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1657191244, states[0] = -95.351681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1670195088, states[0] = -32.470129, states[40]= 0.000351
Saving checkpoint... 
Iteration: 1683291140, states[0] = -95.351849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1696413609, states[0] = -95.270489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1709319714, states[0] = -95.279759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1722467883, states[0] = -95.177862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1735527858, states[0] = 18.062676, states[40]= 0.007507
Saving checkpoint... 
Iteration: 1748618417, states[0] = -95.277878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1761495659, states[0] = -95.239458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774514897, states[0] = 22.329934, states[40]= 0.020698
Saving checkpoint... 
Iteration: 1787633399, states[0] = -95.298323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1800813544, states[0] = -95.099212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813914615, states[0] = -95.112675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827060303, states[0] = 6.930912, states[40]= 0.004839
Saving checkpoint... 
Iteration: 1840139071, states[0] = -60.801849, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1853171094, states[0] = -94.719980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866279194, states[0] = -95.009291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879462789, states[0] = -95.084674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892567186, states[0] = 4.424497, states[40]= 0.004676
Saving checkpoint... 
Iteration: 1905849038, states[0] = -95.048848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918945694, states[0] = -95.077169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932031076, states[0] = 18.438287, states[40]= 0.005956
Saving checkpoint... 
Iteration: 1945081758, states[0] = -3.600374, states[40]= 0.003661
Saving checkpoint... 
Iteration: 1958160954, states[0] = -91.028810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971331309, states[0] = -95.037279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1984128940, states[0] = -47.631110, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1997301796, states[0] = -95.018224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010452209, states[0] = -95.076381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023668122, states[0] = -94.368913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036846310, states[0] = -95.044525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050049003, states[0] = 12.143206, states[40]= 0.004991
Saving checkpoint... 
Iteration: 2063115580, states[0] = -34.011888, states[40]= 0.000294
Saving checkpoint... 
Iteration: 2076303440, states[0] = -95.019187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089433882, states[0] = -95.072695, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.958837
 - CaMKt in component CaMK (millimolar): 0.006949
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.560753
 - nass in component intracellular_ions (millimolar): 6.560813
 - ki in component intracellular_ions (millimolar): 145.417506
 - kss in component intracellular_ions (millimolar): 145.417486
 - cansr in component intracellular_ions (millimolar): 1.309373
 - cajsr in component intracellular_ions (millimolar): 1.271382
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003598
 - hf in component INa (dimensionless): 0.880986
 - hs in component INa (dimensionless): 0.880982
 - j in component INa (dimensionless): 0.880954
 - hsp in component INa (dimensionless): 0.727691
 - jp in component INa (dimensionless): 0.880935
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711539
 - hLp in component INaL (dimensionless): 0.454064
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.621722
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.696701
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934922
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001592
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331796
 - xs1 in component IKs (dimensionless): 0.242331
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997322
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:00:14 (99204): called boinc_finish(0)

</stderr_txt>
]]>


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