𝕏

Task 55845234

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pieske_500-conf_142_1
Workunit 26519256
Created 3 Jul 2024, 5:09:39 UTC
Sent 3 Jul 2024, 6:58:52 UTC
Report deadline 6 Jul 2024, 6:58:52 UTC
Received 3 Jul 2024, 15:36:00 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235353
Run time 2 hours 59 min 52 sec
CPU time 1 hours 58 min 24 sec
Validate state Valid
Credit 45.88
Device peak FLOPS 4.99 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.21 MB
Peak swap size 5.31 MB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pieske_500-conf_142.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pieske_500-conf_142_1_r899717023_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pieske_500-conf_142_1_r899717023_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.992511
     * GNaL_b in INaL: 0.005843
     * Gto_b in Ito: 0.082619
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032172
     * GKs_b in IKs: 0.001938
     * GK1_b in IK1: 0.165481
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 69.730253
     * GKb_b in IKb: 0.003784
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032813
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10952751, states[0] = -87.444992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20798233, states[0] = 6.183988, states[40]= 0.005669
Saving checkpoint... 
Iteration: 30202012, states[0] = -87.402787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40878186, states[0] = -86.058271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52627225, states[0] = -85.594705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61713062, states[0] = -87.404933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70791157, states[0] = 10.875616, states[40]= 0.006052
Saving checkpoint... 
Iteration: 79643356, states[0] = -87.218926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89745656, states[0] = -87.444528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99584332, states[0] = -29.694517, states[40]= 0.000458
Saving checkpoint... 
Iteration: 109488330, states[0] = -87.434417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119239660, states[0] = -87.435583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129457486, states[0] = -87.388347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139223369, states[0] = -87.413409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148369846, states[0] = -77.712579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157554001, states[0] = 2.848115, states[40]= 0.005362
Saving checkpoint... 
Iteration: 166600649, states[0] = -49.748305, states[40]= 0.000030
Saving checkpoint... 
Iteration: 176372141, states[0] = -80.944986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185380384, states[0] = -86.453432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194799410, states[0] = 5.950939, states[40]= 0.005658
Saving checkpoint... 
Iteration: 204404427, states[0] = -87.262405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215090992, states[0] = -37.703027, states[40]= 0.000177
Saving checkpoint... 
Iteration: 224772691, states[0] = 19.991633, states[40]= 0.008576
Saving checkpoint... 
Iteration: 233757700, states[0] = 24.768234, states[40]= 0.076830
Saving checkpoint... 
Iteration: 242940428, states[0] = -87.354670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251991631, states[0] = -87.436669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262041892, states[0] = 10.525935, states[40]= 0.006017
Saving checkpoint... 
Iteration: 270990805, states[0] = -87.435664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280057090, states[0] = 0.570259, states[40]= 0.005069
Saving checkpoint... 
Iteration: 289520825, states[0] = 20.685115, states[40]= 0.009528
Saving checkpoint... 
Iteration: 300392984, states[0] = -87.210707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310176209, states[0] = -87.322168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319915057, states[0] = -87.293185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329409850, states[0] = -87.278509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338581487, states[0] = -26.125852, states[40]= 0.000638
Saving checkpoint... 
Iteration: 348811292, states[0] = -2.916406, states[40]= 0.004451
Saving checkpoint... 
Iteration: 357515922, states[0] = 22.236886, states[40]= 0.015459
Saving checkpoint... 
Iteration: 366447081, states[0] = -87.368054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376031766, states[0] = 15.962728, states[40]= 0.006702
Saving checkpoint... 
Iteration: 386444783, states[0] = -87.363473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395969805, states[0] = -87.407273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405312892, states[0] = -4.392891, states[40]= 0.004129
Saving checkpoint... 
Iteration: 414442981, states[0] = -87.359786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423361013, states[0] = -63.776771, states[40]= 0.000003
Saving checkpoint... 
Iteration: 433242611, states[0] = -87.437621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441940087, states[0] = -87.353728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450387124, states[0] = -87.110490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459020795, states[0] = 20.695902, states[40]= 0.009547
Saving checkpoint... 
Iteration: 468489621, states[0] = -87.434036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477201807, states[0] = -87.376957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485729825, states[0] = -87.421509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494460156, states[0] = -87.391736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502957477, states[0] = -87.387132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512599495, states[0] = -48.261288, states[40]= 0.000038
Saving checkpoint... 
Iteration: 521286707, states[0] = 13.410820, states[40]= 0.006303
Saving checkpoint... 
Iteration: 530022423, states[0] = 20.094842, states[40]= 0.008690
Saving checkpoint... 
Iteration: 538777145, states[0] = 18.137303, states[40]= 0.007334
Saving checkpoint... 
Iteration: 547908412, states[0] = -87.274085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557226302, states[0] = -87.416584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565999783, states[0] = -87.445526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574429156, states[0] = -87.329022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583180088, states[0] = -87.331221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592997103, states[0] = -87.442570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601556592, states[0] = 0.952360, states[40]= 0.005124
Saving checkpoint... 
Iteration: 610160307, states[0] = -87.279540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618733673, states[0] = -87.426454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627431300, states[0] = -87.334016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637089956, states[0] = -36.439581, states[40]= 0.000210
Saving checkpoint... 
Iteration: 645812924, states[0] = -4.423135, states[40]= 0.004122
Saving checkpoint... 
Iteration: 654248948, states[0] = -87.444533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662881069, states[0] = -86.587523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672723576, states[0] = -87.412577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681511639, states[0] = 23.331876, states[40]= 0.032555
Saving checkpoint... 
Iteration: 690163411, states[0] = -87.288252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698766689, states[0] = 22.020421, states[40]= 0.013980
Saving checkpoint... 
Iteration: 707346337, states[0] = -44.280385, states[40]= 0.000070
Saving checkpoint... 
Iteration: 717116904, states[0] = -72.970335, states[40]= 0.000001
Saving checkpoint... 
Iteration: 725795742, states[0] = 8.248030, states[40]= 0.005837
Saving checkpoint... 
Iteration: 734208876, states[0] = -87.389313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742733502, states[0] = -87.426107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752397748, states[0] = -87.237947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760961995, states[0] = -87.394539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769717970, states[0] = -87.404086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778334139, states[0] = -29.366992, states[40]= 0.000474
Saving checkpoint... 
Iteration: 787047739, states[0] = 7.015139, states[40]= 0.005742
Saving checkpoint... 
Iteration: 796779009, states[0] = 17.287866, states[40]= 0.007032
Saving checkpoint... 
Iteration: 805376542, states[0] = -85.000262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814033376, states[0] = 15.154791, states[40]= 0.006551
Saving checkpoint... 
Iteration: 822476649, states[0] = -87.416801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832254398, states[0] = 29.016401, states[40]= 0.133548
Saving checkpoint... 
Iteration: 840799948, states[0] = 5.604069, states[40]= 0.005628
Saving checkpoint... 
Iteration: 849255607, states[0] = 26.729749, states[40]= 0.115574
Saving checkpoint... 
Iteration: 857688357, states[0] = -87.349605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866419774, states[0] = -87.305270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876227162, states[0] = -87.417462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884946985, states[0] = -87.367336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893745639, states[0] = -87.440627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902349765, states[0] = -48.604684, states[40]= 0.000036
Saving checkpoint... 
Iteration: 912223159, states[0] = -87.411727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920845663, states[0] = -43.440519, states[40]= 0.000079
Saving checkpoint... 
Iteration: 929491624, states[0] = -87.435958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938072561, states[0] = -15.137582, states[40]= 0.001709
Saving checkpoint... 
Iteration: 946545730, states[0] = 8.255442, states[40]= 0.005838
Saving checkpoint... 
Iteration: 956085310, states[0] = -30.793381, states[40]= 0.000409
Saving checkpoint... 
Iteration: 964744985, states[0] = -87.439815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973477201, states[0] = -87.417417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982012872, states[0] = 23.024089, states[40]= 0.025510
Saving checkpoint... 
Iteration: 990620183, states[0] = -78.193925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000236507, states[0] = -87.429669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008910830, states[0] = -87.280633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017644154, states[0] = -87.218630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026418618, states[0] = -87.302060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036016947, states[0] = 21.945563, states[40]= 0.013546
Saving checkpoint... 
Iteration: 1044508587, states[0] = 24.310892, states[40]= 0.063220
Saving checkpoint... 
Iteration: 1053116132, states[0] = -71.713215, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1061618832, states[0] = -76.092517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070285670, states[0] = 13.963593, states[40]= 0.006373
Saving checkpoint... 
Iteration: 1079670996, states[0] = -87.308233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088197780, states[0] = -87.368681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096650206, states[0] = -87.247269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105027795, states[0] = 17.845789, states[40]= 0.007220
Saving checkpoint... 
Iteration: 1114964325, states[0] = -87.397983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123566691, states[0] = -8.277015, states[40]= 0.003188
Saving checkpoint... 
Iteration: 1132254417, states[0] = 28.969643, states[40]= 0.133375
Saving checkpoint... 
Iteration: 1140776897, states[0] = 18.247526, states[40]= 0.007381
Saving checkpoint... 
Iteration: 1149404080, states[0] = -87.260271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158959641, states[0] = -87.390186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167522279, states[0] = 20.149872, states[40]= 0.008754
Saving checkpoint... 
Iteration: 1176096050, states[0] = -43.921726, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1184770823, states[0] = 20.686156, states[40]= 0.009529
Saving checkpoint... 
Iteration: 1194407619, states[0] = -87.271073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203017286, states[0] = 21.845470, states[40]= 0.013018
Saving checkpoint... 
Iteration: 1211545642, states[0] = 8.309049, states[40]= 0.005842
Saving checkpoint... 
Iteration: 1220308530, states[0] = -0.567070, states[40]= 0.004891
Saving checkpoint... 
Iteration: 1228675177, states[0] = -87.318678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238497759, states[0] = -87.442640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247042949, states[0] = 9.913154, states[40]= 0.005966
Saving checkpoint... 
Iteration: 1255588498, states[0] = -34.667247, states[40]= 0.000262
Saving checkpoint... 
Iteration: 1264270128, states[0] = 20.930341, states[40]= 0.010000
Saving checkpoint... 
Iteration: 1273756522, states[0] = 25.661156, states[40]= 0.098081
Saving checkpoint... 
Iteration: 1282292416, states[0] = 10.223578, states[40]= 0.005991
Saving checkpoint... 
Iteration: 1291021159, states[0] = 20.565374, states[40]= 0.009328
Saving checkpoint... 
Iteration: 1299802125, states[0] = 4.156656, states[40]= 0.005498
Saving checkpoint... 
Iteration: 1308453917, states[0] = -87.379982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318249619, states[0] = -87.444586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326855757, states[0] = -56.425135, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1335565720, states[0] = -7.233316, states[40]= 0.003446
Saving checkpoint... 
Iteration: 1344299456, states[0] = 5.923329, states[40]= 0.005655
Saving checkpoint... 
Iteration: 1353473899, states[0] = -87.412351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362155878, states[0] = -87.265648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370845753, states[0] = -43.551695, states[40]= 0.000078
Saving checkpoint... 
Iteration: 1379371560, states[0] = -80.168145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387997355, states[0] = -87.442042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397611531, states[0] = -64.538790, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1406117135, states[0] = -73.344513, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1414562017, states[0] = -3.573146, states[40]= 0.004312
Saving checkpoint... 
Iteration: 1423154757, states[0] = -87.262121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432538122, states[0] = 12.644179, states[40]= 0.006216
Saving checkpoint... 
Iteration: 1441247903, states[0] = -87.442592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449782484, states[0] = 15.605769, states[40]= 0.006631
Saving checkpoint... 
Iteration: 1458446029, states[0] = -87.364866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467332264, states[0] = -27.075694, states[40]= 0.000587
Saving checkpoint... 
Iteration: 1477007665, states[0] = 24.789370, states[40]= 0.077411
Saving checkpoint... 
Iteration: 1485593440, states[0] = -40.692882, states[40]= 0.000117
Saving checkpoint... 
Iteration: 1494133854, states[0] = -86.934288, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.320564
 - CaMKt in component CaMK (millimolar): 0.019320
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 6.757219
 - nass in component intracellular_ions (millimolar): 6.757319
 - ki in component intracellular_ions (millimolar): 145.200319
 - kss in component intracellular_ions (millimolar): 145.200292
 - cansr in component intracellular_ions (millimolar): 1.424155
 - cajsr in component intracellular_ions (millimolar): 1.207272
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.007767
 - hf in component INa (dimensionless): 0.678472
 - hs in component INa (dimensionless): 0.678372
 - j in component INa (dimensionless): 0.677694
 - hsp in component INa (dimensionless): 0.432061
 - jp in component INa (dimensionless): 0.675819
 - mL in component INaL (dimensionless): 0.000209
 - hL in component INaL (dimensionless): 0.388851
 - hLp in component INaL (dimensionless): 0.182708
 - a in component Ito (dimensionless): 0.001039
 - iF in component Ito (dimensionless): 0.999508
 - iS in component Ito (dimensionless): 0.294473
 - ap in component Ito (dimensionless): 0.000530
 - iFp in component Ito (dimensionless): 0.999508
 - iSp in component Ito (dimensionless): 0.342507
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.857922
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991111
 - jca in component ICaL (dimensionless): 0.991483
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004188
 - xrf in component IKr (dimensionless): 0.001692
 - xrs in component IKr (dimensionless): 0.672548
 - xs1 in component IKs (dimensionless): 0.382426
 - xs2 in component IKs (dimensionless): 0.000213
 - xk1 in component IK1 (dimensionless): 0.996905
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:34:44 (14000): called boinc_finish(0)

</stderr_txt>
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