Task 55844793

Name	HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_ENDO_4000-conf_539_0
Workunit	26519036
Created	3 Jul 2024, 5:09:18 UTC
Sent	3 Jul 2024, 6:53:09 UTC
Report deadline	6 Jul 2024, 6:53:09 UTC
Received	3 Jul 2024, 20:45:51 UTC
Server state	Over
Outcome	Success
Client state	Done
Exit status	0 (0x00000000)
Computer ID	224057
Run time	1 hours 58 min 34 sec
CPU time	1 hours 58 min 10 sec
Validate state	Valid
Credit	46.01
Device peak FLOPS	3.39 GFLOPS
Application version	Human ventricular cell models optimization v0.02 windows_x86_64
Peak working set size	10.72 MB
Peak swap size	5.34 MB
Peak disk usage	0.03 MB
Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_ENDO_4000-conf_539.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_ENDO_4000-conf_539_0_r9888239_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_ENDO_4000-conf_539_0_r9888239_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.994600
     * GNaL_b in INaL: 0.005506
     * Gto_b in Ito: 0.083909
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031987
     * GKs_b in IKs: 0.001885
     * GK1_b in IK1: 0.163986
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.776026
     * GKb_b in IKb: 0.003777
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028908
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5692961, states[0] = -94.116504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 11441108, states[0] = -94.050579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20018106, states[0] = 31.423915, states[40]= 0.003383
Saving checkpoint... 
Iteration: 28655977, states[0] = -93.974657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37366126, states[0] = -93.945125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45979371, states[0] = -93.924211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54166173, states[0] = -45.084542, states[40]= 0.000452
Saving checkpoint... 
Iteration: 62816093, states[0] = -93.953389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71424985, states[0] = -93.931137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79811388, states[0] = -93.921431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88468482, states[0] = -93.897640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97181221, states[0] = -93.939181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105569700, states[0] = -93.926767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114219919, states[0] = -92.681786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122622543, states[0] = -93.945906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130973706, states[0] = -93.947572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139431090, states[0] = -93.930677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147887844, states[0] = -93.919962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156117966, states[0] = -7.366875, states[40]= 0.002893
Saving checkpoint... 
Iteration: 164457918, states[0] = -93.890934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172894799, states[0] = -93.950466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181154603, states[0] = -93.940262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189617152, states[0] = -93.925598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198124565, states[0] = -12.702140, states[40]= 0.002011
Saving checkpoint... 
Iteration: 206569502, states[0] = -93.936802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214770701, states[0] = -93.952960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223232078, states[0] = -93.937229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231574270, states[0] = -93.926582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240023188, states[0] = 31.328908, states[40]= 0.000672
Saving checkpoint... 
Iteration: 248466679, states[0] = -93.896427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254239501, states[0] = -93.385043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262588060, states[0] = -93.940458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270927283, states[0] = -93.949129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279316382, states[0] = -93.934108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287695085, states[0] = -93.923565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296194631, states[0] = -68.639953, states[40]= 0.000011
Saving checkpoint... 
Iteration: 304559692, states[0] = -93.934254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312869026, states[0] = -93.950969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321031616, states[0] = -93.944908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329361681, states[0] = -93.932480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337631942, states[0] = -93.924899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345892901, states[0] = -93.919465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354264357, states[0] = -93.505425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362698813, states[0] = -93.951400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370918834, states[0] = -93.949187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379262857, states[0] = -93.935729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387461925, states[0] = -93.929259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395574506, states[0] = -93.926173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403883887, states[0] = -93.919482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412237063, states[0] = -93.369652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420423527, states[0] = -93.862985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428677353, states[0] = -93.950184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437030631, states[0] = -93.944658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445255550, states[0] = -93.935827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453844890, states[0] = -93.920077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462277203, states[0] = -93.558514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470737711, states[0] = -93.952152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479046843, states[0] = -93.943892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487456762, states[0] = -93.929159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495819652, states[0] = -93.920454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504157111, states[0] = -37.966918, states[40]= 0.001097
Saving checkpoint... 
Iteration: 512551492, states[0] = -93.931607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520987296, states[0] = -93.946198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529431777, states[0] = -93.929793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537794420, states[0] = -93.920845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546126153, states[0] = -14.023241, states[40]= 0.001846
Saving checkpoint... 
Iteration: 554514953, states[0] = -93.919574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563062229, states[0] = -93.943053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571427866, states[0] = -93.929805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579710898, states[0] = -93.922485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587997210, states[0] = -93.917090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596482632, states[0] = -93.904713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604805521, states[0] = -93.951691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613140610, states[0] = -93.939768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621568146, states[0] = -93.925769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629907282, states[0] = -93.918497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638128101, states[0] = -15.641484, states[40]= 0.001704
Saving checkpoint... 
Iteration: 646579172, states[0] = -93.937783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654986835, states[0] = -93.945881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663354577, states[0] = -93.931874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671682807, states[0] = -93.922879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680035251, states[0] = 28.967463, states[40]= 0.000136
Saving checkpoint... 
Iteration: 688305071, states[0] = -93.653982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696685437, states[0] = -93.949957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705080544, states[0] = -93.941951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713475293, states[0] = -93.928057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721786726, states[0] = -93.920537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730209506, states[0] = -86.627441, states[40]= 0.000001
Saving checkpoint... 
Iteration: 738433183, states[0] = -93.870795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746882620, states[0] = -93.949469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755259747, states[0] = -93.934898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763521930, states[0] = -93.926633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771765335, states[0] = -93.920847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780100788, states[0] = 3.601513, states[40]= 0.003200
Saving checkpoint... 
Iteration: 788317813, states[0] = -93.689561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796564875, states[0] = -93.934278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804738842, states[0] = -93.951332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812999092, states[0] = -93.944995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821191651, states[0] = -93.937260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829557573, states[0] = -93.925521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837860183, states[0] = -93.918827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846244756, states[0] = -93.411792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854588887, states[0] = -93.939132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863069304, states[0] = -93.942013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871388321, states[0] = -93.930271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879767393, states[0] = -93.920534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888150824, states[0] = -33.179839, states[40]= 0.001752
Saving checkpoint... 
Iteration: 896395574, states[0] = -93.831863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903178869, states[0] = -93.937545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911482311, states[0] = -93.927360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919974160, states[0] = -93.916630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928295606, states[0] = -93.623631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936723850, states[0] = -93.950736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945091987, states[0] = -93.940886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953603469, states[0] = -93.924046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961911960, states[0] = -93.917581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970239605, states[0] = -93.383791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978521893, states[0] = -93.921121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986817233, states[0] = -93.950541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995178512, states[0] = -93.937328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001063867, states[0] = -93.941889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009451888, states[0] = -93.927992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017677240, states[0] = -93.922136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025967726, states[0] = -93.916470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034271460, states[0] = -93.533913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042545156, states[0] = -93.928510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051039224, states[0] = -93.942770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059588346, states[0] = -93.924157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068024994, states[0] = 31.093027, states[40]= 0.000395
Saving checkpoint... 
Iteration: 1076357037, states[0] = -93.774296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084756728, states[0] = -93.950785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092947489, states[0] = -93.946320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101278490, states[0] = -93.933363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109589146, states[0] = -93.924011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117890121, states[0] = -93.917577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126081196, states[0] = 12.705177, states[40]= 0.001630
Saving checkpoint... 
Iteration: 1134452503, states[0] = -93.884820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142784840, states[0] = -93.950580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151136558, states[0] = -93.938580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156843138, states[0] = -93.949559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165048516, states[0] = -93.942105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173518558, states[0] = -93.925696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181850962, states[0] = -93.918135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190173319, states[0] = -50.685316, states[40]= 0.000209
Saving checkpoint... 
Iteration: 1198497504, states[0] = -93.910566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206887550, states[0] = -93.948160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215248540, states[0] = -93.934150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223643253, states[0] = -93.922407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232038444, states[0] = 28.108131, states[40]= 0.000156
Saving checkpoint... 
Iteration: 1240272627, states[0] = -93.538181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248704715, states[0] = -93.949406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257205090, states[0] = -93.935656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263144707, states[0] = -93.937977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271475692, states[0] = -93.926645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280054992, states[0] = 22.792353, states[40]= 0.000409
Saving checkpoint... 
Iteration: 1288629515, states[0] = -93.943993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297153249, states[0] = -93.937555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305717059, states[0] = -93.920528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314369305, states[0] = -93.794264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322807946, states[0] = -93.949857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331315561, states[0] = -93.931500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339786063, states[0] = -93.918999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348165615, states[0] = -44.577988, states[40]= 0.000489
Saving checkpoint... 
Iteration: 1356792820, states[0] = -93.949971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365107645, states[0] = -93.939200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373347451, states[0] = -93.930327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381495622, states[0] = -93.925807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387350128, states[0] = -93.930204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395947531, states[0] = -93.915878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404588164, states[0] = -93.937623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413133265, states[0] = -93.938054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421599352, states[0] = -93.922973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430226243, states[0] = -93.206910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438779150, states[0] = -93.949878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447416400, states[0] = -93.927955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456001037, states[0] = 47.891815, states[40]= 0.338285
Saving checkpoint... 
Iteration: 1464528394, states[0] = -93.922191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472920520, states[0] = -93.946367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481358057, states[0] = -93.929709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489882865, states[0] = -93.916774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498117851, states[0] = -7.277421, states[40]= 0.002907
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.790724
 - CaMKt in component CaMK (millimolar): 0.002107
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.767130
 - nass in component intracellular_ions (millimolar): 6.767254
 - ki in component intracellular_ions (millimolar): 145.087963
 - kss in component intracellular_ions (millimolar): 145.087952
 - cansr in component intracellular_ions (millimolar): 1.845898
 - cajsr in component intracellular_ions (millimolar): 1.845740
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004048
 - hf in component INa (dimensionless): 0.859344
 - hs in component INa (dimensionless): 0.859345
 - j in component INa (dimensionless): 0.859349
 - hsp in component INa (dimensionless): 0.688076
 - jp in component INa (dimensionless): 0.859351
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.698933
 - hLp in component INaL (dimensionless): 0.503042
 - a in component Ito (dimensionless): 0.000672
 - iF in component Ito (dimensionless): 0.999842
 - iS in component Ito (dimensionless): 0.991408
 - ap in component Ito (dimensionless): 0.000342
 - iFp in component Ito (dimensionless): 0.999842
 - iSp in component Ito (dimensionless): 0.996550
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996479
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005411
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.008135
 - xs1 in component IKs (dimensionless): 0.041201
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997614
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:00:20 (16148): called boinc_finish(0)

</stderr_txt>
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