𝕏

Task 55844684

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_ENDO_2000-conf_438_1
Workunit 26518981
Created 3 Jul 2024, 5:09:18 UTC
Sent 3 Jul 2024, 6:53:09 UTC
Report deadline 6 Jul 2024, 6:53:09 UTC
Received 3 Jul 2024, 19:40:17 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224057
Run time 1 hours 59 min 25 sec
CPU time 1 hours 58 min 40 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 3.39 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.73 MB
Peak swap size 5.34 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_ENDO_2000-conf_438.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_ENDO_2000-conf_438_1_r336404144_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_ENDO_2000-conf_438_1_r336404144_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.554845
     * GNaL_b in INaL: 0.006059
     * Gto_b in Ito: 0.083726
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031556
     * GKs_b in IKs: 0.001935
     * GK1_b in IK1: 0.162470
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.006150
     * GKb_b in IKb: 0.003775
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031838
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5692324, states[0] = -94.240095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14108354, states[0] = -2.569628, states[40]= 0.003721
Saving checkpoint... 
Iteration: 22316945, states[0] = -93.906241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30723027, states[0] = -94.109057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39086602, states[0] = 9.477554, states[40]= 0.002196
Saving checkpoint... 
Iteration: 47387633, states[0] = -93.992711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55777107, states[0] = -94.100395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64298591, states[0] = -93.822464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72575347, states[0] = -94.091509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80947188, states[0] = -94.094106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89241428, states[0] = -93.600337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97453205, states[0] = -94.049560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103257652, states[0] = -93.675893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111689755, states[0] = -94.102077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120114724, states[0] = -7.000375, states[40]= 0.002882
Saving checkpoint... 
Iteration: 128319088, states[0] = -93.877601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136664626, states[0] = -94.101462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145041552, states[0] = 26.850516, states[40]= 0.000187
Saving checkpoint... 
Iteration: 153315393, states[0] = -93.868815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161669518, states[0] = -94.101701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169990634, states[0] = -94.092813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175845851, states[0] = -94.099768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184143595, states[0] = -30.709257, states[40]= 0.001845
Saving checkpoint... 
Iteration: 192529851, states[0] = -94.082662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200924486, states[0] = -94.096105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209360374, states[0] = -93.956749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217831447, states[0] = -94.100194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226176413, states[0] = -57.723083, states[40]= 0.000064
Saving checkpoint... 
Iteration: 234457321, states[0] = -94.052290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243006271, states[0] = 30.915616, states[40]= 0.217058
Saving checkpoint... 
Iteration: 251292203, states[0] = -93.804333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257044595, states[0] = 25.849708, states[40]= 0.000224
Saving checkpoint... 
Iteration: 265398176, states[0] = -94.004951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273791809, states[0] = -94.101253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282002974, states[0] = 38.973939, states[40]= 0.660808
Saving checkpoint... 
Iteration: 290187307, states[0] = -67.715195, states[40]= 0.000012
Saving checkpoint... 
Iteration: 298671450, states[0] = -94.101245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304824533, states[0] = -94.100047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313475982, states[0] = -94.061911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321842891, states[0] = -94.099263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330339174, states[0] = -93.919712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338798700, states[0] = -94.100738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347316054, states[0] = -93.869653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355743873, states[0] = -94.101787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364210301, states[0] = -92.234555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372553672, states[0] = -94.087712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380813927, states[0] = -94.100045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389392794, states[0] = -93.998512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398072861, states[0] = 15.270647, states[40]= 0.001129
Saving checkpoint... 
Iteration: 406410091, states[0] = -94.016108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414736303, states[0] = -94.101556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423165490, states[0] = -48.463532, states[40]= 0.000260
Saving checkpoint... 
Iteration: 431529942, states[0] = -94.081566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439997453, states[0] = -94.091241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448574018, states[0] = -94.091258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456977722, states[0] = -94.092182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465382876, states[0] = -93.986534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473598744, states[0] = -94.094782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481949371, states[0] = -94.093514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490214608, states[0] = -93.075959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497747787, states[0] = -94.101044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504944596, states[0] = -94.093643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513143378, states[0] = -30.540735, states[40]= 0.001862
Saving checkpoint... 
Iteration: 521350196, states[0] = -93.938705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529467768, states[0] = -94.056672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537695222, states[0] = -94.100724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545775825, states[0] = -94.100320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553992214, states[0] = -94.090950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562163544, states[0] = -46.828644, states[40]= 0.000326
Saving checkpoint... 
Iteration: 570421075, states[0] = -94.025045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578518635, states[0] = -94.077479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586675548, states[0] = -94.099971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595034647, states[0] = 28.930658, states[40]= 0.000134
Saving checkpoint... 
Iteration: 603205279, states[0] = -89.425107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608853309, states[0] = -94.097421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614583176, states[0] = -94.091919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623080484, states[0] = 12.081182, states[40]= 0.001629
Saving checkpoint... 
Iteration: 631527628, states[0] = -94.079922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639576140, states[0] = -94.090672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648097965, states[0] = 3.821665, states[40]= 0.003036
Saving checkpoint... 
Iteration: 656408641, states[0] = -94.013499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664838598, states[0] = -94.097739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673320512, states[0] = -93.878612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681900819, states[0] = -94.094925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690317003, states[0] = -93.870232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698722322, states[0] = -94.100188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707262823, states[0] = -93.695680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715590371, states[0] = -94.092474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724079058, states[0] = 12.691361, states[40]= 0.001526
Saving checkpoint... 
Iteration: 732452777, states[0] = -94.047112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740650054, states[0] = -94.098051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748973967, states[0] = -94.090932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757339800, states[0] = -93.918776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765549271, states[0] = -94.084796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774046130, states[0] = 25.331867, states[40]= 0.000246
Saving checkpoint... 
Iteration: 782462024, states[0] = -94.052291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790793137, states[0] = -94.098667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799138135, states[0] = -26.429437, states[40]= 0.002048
Saving checkpoint... 
Iteration: 807640306, states[0] = -94.097103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815937627, states[0] = -94.092457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824370552, states[0] = -93.968631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832750419, states[0] = -94.099357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841134011, states[0] = -23.170998, states[40]= 0.001851
Saving checkpoint... 
Iteration: 849453926, states[0] = -94.047234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857731652, states[0] = -94.099390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866183050, states[0] = -63.597588, states[40]= 0.000024
Saving checkpoint... 
Iteration: 874408233, states[0] = -94.012028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882615948, states[0] = -94.094695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890999615, states[0] = -94.088897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899376159, states[0] = -93.975839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907647898, states[0] = -94.097098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915936090, states[0] = -94.092040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924125826, states[0] = -16.392111, states[40]= 0.001597
Saving checkpoint... 
Iteration: 932315890, states[0] = -93.866325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940635464, states[0] = -94.096100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949041683, states[0] = 26.807293, states[40]= 0.000189
Saving checkpoint... 
Iteration: 957422987, states[0] = -94.024717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965638600, states[0] = -94.096204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973885077, states[0] = -94.094219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982246453, states[0] = -93.621359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990507891, states[0] = -94.071857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998688141, states[0] = -94.098297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006983987, states[0] = -94.089137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015160973, states[0] = -44.679750, states[40]= 0.000435
Saving checkpoint... 
Iteration: 1023412593, states[0] = -94.015361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031757776, states[0] = -94.098268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040190369, states[0] = -70.956398, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1048412090, states[0] = -94.014776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057035029, states[0] = 28.824352, states[40]= 0.000135
Saving checkpoint... 
Iteration: 1065410226, states[0] = -94.012964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073637271, states[0] = -94.095575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081981129, states[0] = -94.088915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090348887, states[0] = -93.933615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098720775, states[0] = -94.098209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106996017, states[0] = -94.088017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115376829, states[0] = -93.975642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123566109, states[0] = -94.086505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131917227, states[0] = -94.091908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140317385, states[0] = -93.868897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148627549, states[0] = -94.094445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156902592, states[0] = -94.092492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165217454, states[0] = -93.295221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173623885, states[0] = -94.094005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181852652, states[0] = -94.094616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190092092, states[0] = 6.801849, states[40]= 0.002572
Saving checkpoint... 
Iteration: 1198511743, states[0] = -94.072160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206916614, states[0] = -94.091567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215248122, states[0] = -93.628049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223651315, states[0] = -94.095737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232053826, states[0] = 22.614788, states[40]= 0.000390
Saving checkpoint... 
Iteration: 1240459273, states[0] = -94.048460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248765555, states[0] = -94.097060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257074725, states[0] = 14.507763, states[40]= 0.001240
Saving checkpoint... 
Iteration: 1265446184, states[0] = -94.040287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273620938, states[0] = -94.093243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281805723, states[0] = -94.095862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290337257, states[0] = -93.911215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298657544, states[0] = -94.095699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306933457, states[0] = -94.090238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315366969, states[0] = -93.961113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323537204, states[0] = -94.079110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331896266, states[0] = -94.091928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340326956, states[0] = -93.889745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348643881, states[0] = -94.094668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356845354, states[0] = -94.094050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365289878, states[0] = -93.791417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373533174, states[0] = -94.077797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381902964, states[0] = -94.091362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390162022, states[0] = -45.550349, states[40]= 0.000388
Saving checkpoint... 
Iteration: 1398524720, states[0] = -94.075282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406527891, states[0] = -94.076165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414734452, states[0] = -94.096626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422997997, states[0] = -94.086351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431307820, states[0] = -93.843322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439626730, states[0] = -94.092938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448061112, states[0] = 19.899961, states[40]= 0.000598
Saving checkpoint... 
Iteration: 1456235878, states[0] = -93.566360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464462192, states[0] = -94.049008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472875975, states[0] = -94.092166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481002491, states[0] = 41.851276, states[40]= 0.751417
Saving checkpoint... 
Iteration: 1489420431, states[0] = -94.019944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497812603, states[0] = -94.094570, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.961803
 - CaMKt in component CaMK (millimolar): 0.005765
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 6.828908
 - nass in component intracellular_ions (millimolar): 6.829026
 - ki in component intracellular_ions (millimolar): 145.008252
 - kss in component intracellular_ions (millimolar): 145.008238
 - cansr in component intracellular_ions (millimolar): 1.845886
 - cajsr in component intracellular_ions (millimolar): 1.844990
 - cai in component intracellular_ions (millimolar): 0.000101
 - m in component INa (dimensionless): 0.003979
 - hf in component INa (dimensionless): 0.862708
 - hs in component INa (dimensionless): 0.862710
 - j in component INa (dimensionless): 0.862723
 - hsp in component INa (dimensionless): 0.694086
 - jp in component INa (dimensionless): 0.862729
 - mL in component INaL (dimensionless): 0.000059
 - hL in component INaL (dimensionless): 0.703562
 - hLp in component INaL (dimensionless): 0.490701
 - a in component Ito (dimensionless): 0.000664
 - iF in component Ito (dimensionless): 0.999846
 - iS in component Ito (dimensionless): 0.885535
 - ap in component Ito (dimensionless): 0.000338
 - iFp in component Ito (dimensionless): 0.999846
 - iSp in component Ito (dimensionless): 0.925218
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.970892
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004550
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.111671
 - xs1 in component IKs (dimensionless): 0.137124
 - xs2 in component IKs (dimensionless): 0.000098
 - xk1 in component IK1 (dimensionless): 0.997573
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:40:07 (25004): called boinc_finish(0)

</stderr_txt>
]]>