𝕏

Task 55842746

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-CLVPET_Block_Ks_95-conf_224_1
Workunit 26518015
Created 3 Jul 2024, 5:08:06 UTC
Sent 3 Jul 2024, 6:47:41 UTC
Report deadline 6 Jul 2024, 9:40:29 UTC
Received 3 Jul 2024, 15:09:01 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 54 min 24 sec
CPU time 1 hours 47 min 37 sec
Validate state Valid
Credit 49.74
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.80 MB
Peak swap size 4.13 GB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-CLVPET_Block_Ks_95-conf_224.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-CLVPET_Block_Ks_95-conf_224_1_r1416332460_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-CLVPET_Block_Ks_95-conf_224_1_r1416332460_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 105.856510
     * GNaL_b in INaL: 0.006224
     * Gto_b in Ito: 0.083619
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031493
     * GKs_b in IKs: 0.000095
     * GK1_b in IK1: 0.165203
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 71.405330
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032226
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13566051, states[0] = 11.501208, states[40]= 0.004533
Saving checkpoint... 
Iteration: 26178887, states[0] = -93.094489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38361831, states[0] = -94.879760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51042637, states[0] = 21.186166, states[40]= 0.002417
Saving checkpoint... 
Iteration: 62882747, states[0] = -94.885687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75651818, states[0] = -56.581616, states[40]= 0.000038
Saving checkpoint... 
Iteration: 88865000, states[0] = -94.869084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101809729, states[0] = -94.808646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115211420, states[0] = -94.559569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127941193, states[0] = -94.908967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141245170, states[0] = -94.673938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153589673, states[0] = 0.189802, states[40]= 0.004766
Saving checkpoint... 
Iteration: 166321914, states[0] = -94.822902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179524778, states[0] = 26.726167, states[40]= 0.001849
Saving checkpoint... 
Iteration: 192543822, states[0] = 20.894684, states[40]= 0.002528
Saving checkpoint... 
Iteration: 205721805, states[0] = -94.597326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217590634, states[0] = -0.422369, states[40]= 0.004701
Saving checkpoint... 
Iteration: 230766661, states[0] = -94.728101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243171938, states[0] = -83.044016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 256027426, states[0] = 26.077142, states[40]= 0.001763
Saving checkpoint... 
Iteration: 269349954, states[0] = -94.852494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282030426, states[0] = 25.252077, states[40]= 0.001806
Saving checkpoint... 
Iteration: 295028031, states[0] = 25.917739, states[40]= 0.001763
Saving checkpoint... 
Iteration: 307606031, states[0] = -12.728578, states[40]= 0.002179
Saving checkpoint... 
Iteration: 320181771, states[0] = -93.285570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333189693, states[0] = -94.364782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345734189, states[0] = -94.639082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358652381, states[0] = -56.827925, states[40]= 0.000037
Saving checkpoint... 
Iteration: 371779258, states[0] = -94.754273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385223695, states[0] = -94.603336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398098832, states[0] = -6.441445, states[40]= 0.003592
Saving checkpoint... 
Iteration: 411957300, states[0] = -94.912382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425069662, states[0] = 10.792654, states[40]= 0.004477
Saving checkpoint... 
Iteration: 438037567, states[0] = 23.028324, states[40]= 0.002130
Saving checkpoint... 
Iteration: 451338401, states[0] = -94.840389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464314443, states[0] = -94.811771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477351965, states[0] = -94.853542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489611432, states[0] = -17.700410, states[40]= 0.001536
Saving checkpoint... 
Iteration: 502874415, states[0] = -94.871667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515692892, states[0] = -94.442517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528427360, states[0] = -94.901088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541812285, states[0] = -94.808528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554566143, states[0] = 12.334569, states[40]= 0.004249
Saving checkpoint... 
Iteration: 567172558, states[0] = -84.060955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579527002, states[0] = 26.187340, states[40]= 0.001766
Saving checkpoint... 
Iteration: 591943245, states[0] = -94.907021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604335613, states[0] = -94.836846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616864361, states[0] = -94.863596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630229359, states[0] = -94.622058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643150228, states[0] = -54.528367, states[40]= 0.000053
Saving checkpoint... 
Iteration: 655500388, states[0] = -46.734061, states[40]= 0.000003
Saving checkpoint... 
Iteration: 668316746, states[0] = -94.814072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681139956, states[0] = -43.976511, states[40]= 0.000254
Saving checkpoint... 
Iteration: 693950998, states[0] = -94.909303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706810637, states[0] = -94.805605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719896277, states[0] = -94.884984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731811073, states[0] = -94.806122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744065757, states[0] = 12.499794, states[40]= 0.004223
Saving checkpoint... 
Iteration: 755641187, states[0] = -45.201531, states[40]= 0.000214
Saving checkpoint... 
Iteration: 768800046, states[0] = -94.789581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781221573, states[0] = -94.594191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794788322, states[0] = -94.769752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807453882, states[0] = -94.909815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819878064, states[0] = -94.873056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832787364, states[0] = -94.767882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846028556, states[0] = 25.777033, states[40]= 0.001768
Saving checkpoint... 
Iteration: 858851030, states[0] = -94.851247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871117797, states[0] = -23.485502, states[40]= 0.001411
Saving checkpoint... 
Iteration: 883940536, states[0] = -94.904938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895451222, states[0] = -94.908619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908804650, states[0] = -94.796137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921808705, states[0] = -94.802044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934860623, states[0] = -94.859347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947583664, states[0] = 3.802717, states[40]= 0.004949
Saving checkpoint... 
Iteration: 960752904, states[0] = -94.691507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973284032, states[0] = -94.761201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986456573, states[0] = -94.909993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999657400, states[0] = -62.378877, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1012883721, states[0] = -94.876148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026235593, states[0] = -94.640976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038609569, states[0] = -15.981131, states[40]= 0.001693
Saving checkpoint... 
Iteration: 1051523838, states[0] = 26.939262, states[40]= 0.001937
Saving checkpoint... 
Iteration: 1064171251, states[0] = -81.875562, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1076274560, states[0] = -94.742052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090124447, states[0] = -29.455184, states[40]= 0.001223
Saving checkpoint... 
Iteration: 1103363782, states[0] = -94.861295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116142552, states[0] = -46.572950, states[40]= 0.000177
Saving checkpoint... 
Iteration: 1129011508, states[0] = 28.227621, states[40]= 0.029824
Saving checkpoint... 
Iteration: 1142089304, states[0] = 0.440917, states[40]= 0.004790
Saving checkpoint... 
Iteration: 1154406396, states[0] = -94.888897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166875582, states[0] = -94.870000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179636732, states[0] = -40.826374, states[40]= 0.000387
Saving checkpoint... 
Iteration: 1192784808, states[0] = -94.761821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205971785, states[0] = -94.913557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218396716, states[0] = -94.883358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230416802, states[0] = -94.893753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242470169, states[0] = -94.912986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254737273, states[0] = -94.645394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267920170, states[0] = -94.895163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280669253, states[0] = -78.532172, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1291517467, states[0] = 27.982556, states[40]= 0.005092
Saving checkpoint... 
Iteration: 1301853580, states[0] = -94.851886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313294939, states[0] = -94.779233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324121213, states[0] = -26.548065, states[40]= 0.001372
Saving checkpoint... 
Iteration: 1334914301, states[0] = -94.892173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347107941, states[0] = -14.478197, states[40]= 0.001887
Saving checkpoint... 
Iteration: 1358481273, states[0] = -94.915388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368649778, states[0] = -54.048267, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1378464302, states[0] = -94.910834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389155829, states[0] = -60.597406, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1399820862, states[0] = -94.816614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410524255, states[0] = 26.847986, states[40]= 0.001894
Saving checkpoint... 
Iteration: 1421174703, states[0] = -87.361758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432311314, states[0] = -94.803809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442586242, states[0] = 2.318260, states[40]= 0.004914
Saving checkpoint... 
Iteration: 1451503775, states[0] = 35.168557, states[40]= 0.368740
Saving checkpoint... 
Iteration: 1461403735, states[0] = -94.886335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471613672, states[0] = -19.749909, states[40]= 0.001437
Saving checkpoint... 
Iteration: 1482040824, states[0] = 21.935085, states[40]= 0.002328
Saving checkpoint... 
Iteration: 1492827120, states[0] = -94.823901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504252040, states[0] = -39.026375, states[40]= 0.000478
Saving checkpoint... 
Iteration: 1516324318, states[0] = -94.991625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527264325, states[0] = 27.930990, states[40]= 0.012849
Saving checkpoint... 
Iteration: 1538551904, states[0] = 18.357542, states[40]= 0.002072
Saving checkpoint... 
Iteration: 1549925578, states[0] = -76.431000, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1561449606, states[0] = -94.671250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572817139, states[0] = -94.700377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584473612, states[0] = -94.600276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595861303, states[0] = -94.599223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606935835, states[0] = -94.577736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617781628, states[0] = -94.278057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1629048030, states[0] = -94.501537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640067699, states[0] = 15.892191, states[40]= 0.003762
Saving checkpoint... 
Iteration: 1651844656, states[0] = -94.484305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662668636, states[0] = -48.386175, states[40]= 0.000148
Saving checkpoint... 
Iteration: 1673155656, states[0] = -94.487751, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.346709
 - CaMKt in component CaMK (millimolar): 0.001136
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.324003
 - nass in component intracellular_ions (millimolar): 6.324090
 - ki in component intracellular_ions (millimolar): 145.573129
 - kss in component intracellular_ions (millimolar): 145.573118
 - cansr in component intracellular_ions (millimolar): 1.570979
 - cajsr in component intracellular_ions (millimolar): 1.570986
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003827
 - hf in component INa (dimensionless): 0.870028
 - hs in component INa (dimensionless): 0.870028
 - j in component INa (dimensionless): 0.870029
 - hsp in component INa (dimensionless): 0.707336
 - jp in component INa (dimensionless): 0.870030
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.714289
 - hLp in component INaL (dimensionless): 0.521991
 - a in component Ito (dimensionless): 0.000647
 - iF in component Ito (dimensionless): 0.999856
 - iS in component Ito (dimensionless): 0.997727
 - ap in component Ito (dimensionless): 0.000330
 - iFp in component Ito (dimensionless): 0.999856
 - iSp in component Ito (dimensionless): 0.999246
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998816
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003033
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001821
 - xs1 in component IKs (dimensionless): 0.023524
 - xs2 in component IKs (dimensionless): 0.000093
 - xk1 in component IK1 (dimensionless): 0.997479
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:48:39 (29960): called boinc_finish(0)

</stderr_txt>
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