𝕏

Task 55842622

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_MID_1000-conf_223_1
Workunit 26517953
Created 3 Jul 2024, 5:08:01 UTC
Sent 3 Jul 2024, 6:36:57 UTC
Report deadline 6 Jul 2024, 6:36:57 UTC
Received 3 Jul 2024, 21:38:53 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227233
Run time 4 hours 26 min 3 sec
CPU time 2 hours 10 min 32 sec
Validate state Valid
Credit 46.20
Device peak FLOPS 3.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 6.59 MB
Peak swap size 32.97 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.20.7</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_MID_1000-conf_223.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_MID_1000-conf_223_1_r1987729134_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_MID_1000-conf_223_1_r1987729134_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 107.189664
     * GNaL_b in INaL: 0.006089
     * Gto_b in Ito: 0.087651
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032290
     * GKs_b in IKs: 0.001958
     * GK1_b in IK1: 0.163116
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.520822
     * GKb_b in IKb: 0.003784
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029565
     * celltype in environment: 2.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11388242, states[0] = -94.325386, states[40]= 0.000001
Saving checkpoint... 
Iteration: 22772388, states[0] = -93.891782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34180040, states[0] = -31.690622, states[40]= 0.013311
Saving checkpoint... 
Iteration: 45715371, states[0] = -57.507871, states[40]= 0.000826
Saving checkpoint... 
Iteration: 57144110, states[0] = -17.325533, states[40]= 0.006439
Saving checkpoint... 
Iteration: 68665263, states[0] = -29.767437, states[40]= 0.017966
Saving checkpoint... 
Iteration: 80053049, states[0] = 28.727922, states[40]= 0.000003
Saving checkpoint... 
Iteration: 91503897, states[0] = 23.260950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102814837, states[0] = -94.285129, states[40]= 0.000001
Saving checkpoint... 
Iteration: 114296830, states[0] = -94.204760, states[40]= 0.000001
Saving checkpoint... 
Iteration: 125572598, states[0] = 20.809392, states[40]= 0.000091
Saving checkpoint... 
Iteration: 137071515, states[0] = 21.218726, states[40]= 0.000080
Saving checkpoint... 
Iteration: 148399456, states[0] = -94.501066, states[40]= 0.000001
Saving checkpoint... 
Iteration: 159750089, states[0] = -93.846401, states[40]= 0.000001
Saving checkpoint... 
Iteration: 171296007, states[0] = -94.205890, states[40]= 0.000001
Saving checkpoint... 
Iteration: 182525410, states[0] = 34.684901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193902720, states[0] = -94.503498, states[40]= 0.000001
Saving checkpoint... 
Iteration: 205463844, states[0] = -94.553109, states[40]= 0.000001
Saving checkpoint... 
Iteration: 216713152, states[0] = -66.767006, states[40]= 0.000288
Saving checkpoint... 
Iteration: 228331852, states[0] = -94.353501, states[40]= 0.000001
Saving checkpoint... 
Iteration: 239782088, states[0] = -94.116298, states[40]= 0.000001
Saving checkpoint... 
Iteration: 250877935, states[0] = -94.461731, states[40]= 0.000001
Saving checkpoint... 
Iteration: 262095567, states[0] = 10.176550, states[40]= 0.001702
Saving checkpoint... 
Iteration: 273423960, states[0] = -94.518025, states[40]= 0.000001
Saving checkpoint... 
Iteration: 284655516, states[0] = -27.769497, states[40]= 0.021193
Saving checkpoint... 
Iteration: 296068440, states[0] = 22.393423, states[40]= 0.000055
Saving checkpoint... 
Iteration: 307693429, states[0] = -49.567907, states[40]= 0.003051
Saving checkpoint... 
Iteration: 319338408, states[0] = -94.363734, states[40]= 0.000001
Saving checkpoint... 
Iteration: 330921255, states[0] = -94.508953, states[40]= 0.000001
Saving checkpoint... 
Iteration: 342240890, states[0] = -93.673385, states[40]= 0.000001
Saving checkpoint... 
Iteration: 353664188, states[0] = -31.828251, states[40]= 0.017346
Saving checkpoint... 
Iteration: 365075753, states[0] = 19.318419, states[40]= 0.000156
Saving checkpoint... 
Iteration: 376565049, states[0] = 23.764456, states[40]= 0.000032
Saving checkpoint... 
Iteration: 388098168, states[0] = 8.887587, states[40]= 0.002208
Saving checkpoint... 
Iteration: 399364764, states[0] = -94.419990, states[40]= 0.000001
Saving checkpoint... 
Iteration: 410910287, states[0] = -94.488500, states[40]= 0.000001
Saving checkpoint... 
Iteration: 422323633, states[0] = -94.303081, states[40]= 0.000001
Saving checkpoint... 
Iteration: 433640882, states[0] = -19.754105, states[40]= 0.010498
Saving checkpoint... 
Iteration: 444866779, states[0] = -94.418836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 456231914, states[0] = -92.336021, states[40]= 0.000003
Saving checkpoint... 
Iteration: 467627927, states[0] = -10.075844, states[40]= 0.006818
Saving checkpoint... 
Iteration: 478945089, states[0] = -94.511293, states[40]= 0.000001
Saving checkpoint... 
Iteration: 490512369, states[0] = 32.677489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502052109, states[0] = 28.566171, states[40]= 0.000003
Saving checkpoint... 
Iteration: 513615421, states[0] = -0.836632, states[40]= 0.007235
Saving checkpoint... 
Iteration: 525053052, states[0] = 28.245216, states[40]= 0.000004
Saving checkpoint... 
Iteration: 536446549, states[0] = -94.505712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 547794289, states[0] = -94.155256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 559138550, states[0] = -18.155265, states[40]= 0.008351
Saving checkpoint... 
Iteration: 570535395, states[0] = 33.258812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582068503, states[0] = 22.381884, states[40]= 0.000054
Saving checkpoint... 
Iteration: 611941655, states[0] = -94.493554, states[40]= 0.000001
Saving checkpoint... 
Iteration: 623295620, states[0] = -94.153888, states[40]= 0.000001
Saving checkpoint... 
Iteration: 634771176, states[0] = -93.991736, states[40]= 0.000001
Saving checkpoint... 
Iteration: 646237540, states[0] = -93.473418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 657587983, states[0] = 13.828714, states[40]= 0.000726
Saving checkpoint... 
Iteration: 669009271, states[0] = 30.645984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680351073, states[0] = -94.356414, states[40]= 0.000001
Saving checkpoint... 
Iteration: 691555239, states[0] = 27.487747, states[40]= 0.000006
Saving checkpoint... 
Iteration: 703098415, states[0] = 8.784985, states[40]= 0.002221
Saving checkpoint... 
Iteration: 714568480, states[0] = 22.397421, states[40]= 0.000054
Saving checkpoint... 
Iteration: 726034714, states[0] = 33.405276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737380538, states[0] = -94.410154, states[40]= 0.000001
Saving checkpoint... 
Iteration: 748431331, states[0] = -94.469842, states[40]= 0.000001
Saving checkpoint... 
Iteration: 759572566, states[0] = 20.700030, states[40]= 0.000098
Saving checkpoint... 
Iteration: 770773101, states[0] = -93.990794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 782387863, states[0] = -94.416570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 793753180, states[0] = -93.810162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 804995468, states[0] = -94.497966, states[40]= 0.000001
Saving checkpoint... 
Iteration: 806522944, states[0] = 34.793141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832132775, states[0] = -13.834693, states[40]= 0.006253
Saving checkpoint... 
Iteration: 858991109, states[0] = -94.490381, states[40]= 0.000001
Saving checkpoint... 
Iteration: 885149391, states[0] = -24.698774, states[40]= 0.019525
Saving checkpoint... 
Iteration: 912046342, states[0] = 30.443514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 932793672, states[0] = -94.107111, states[40]= 0.000001
Saving checkpoint... 
Iteration: 947095887, states[0] = 10.057259, states[40]= 0.001715
Saving checkpoint... 
Iteration: 959725147, states[0] = -84.930926, states[40]= 0.000020
Saving checkpoint... 
Iteration: 970889899, states[0] = -94.397991, states[40]= 0.000001
Saving checkpoint... 
Iteration: 982130919, states[0] = -12.358435, states[40]= 0.006295
Saving checkpoint... 
Iteration: 993379290, states[0] = -94.378621, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1004198411, states[0] = -53.406432, states[40]= 0.001873
Saving checkpoint... 
Iteration: 1015224649, states[0] = -84.112096, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1026267639, states[0] = -93.917762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1037422155, states[0] = -94.428472, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1048301921, states[0] = -94.137419, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1059512202, states[0] = 32.615395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070807937, states[0] = -94.163563, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1081776813, states[0] = -93.982028, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1092997675, states[0] = -94.465581, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1104283642, states[0] = -94.026336, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1115194185, states[0] = -50.141776, states[40]= 0.002818
Saving checkpoint... 
Iteration: 1126223356, states[0] = -81.789271, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1137235720, states[0] = -93.222046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1148184230, states[0] = -43.046702, states[40]= 0.006260
Saving checkpoint... 
Iteration: 1159029091, states[0] = 34.360227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170047804, states[0] = 30.007524, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1181135559, states[0] = -15.899536, states[40]= 0.006650
Saving checkpoint... 
Iteration: 1192221142, states[0] = -77.860083, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1203011921, states[0] = 32.469344, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1213918006, states[0] = -94.404131, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1224987249, states[0] = -94.446977, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1236561774, states[0] = 25.089355, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1247455806, states[0] = -94.429687, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1258738468, states[0] = -93.457244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1270112279, states[0] = 1.231338, states[40]= 0.006193
Saving checkpoint... 
Iteration: 1281271535, states[0] = -93.919027, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1292511640, states[0] = 32.313997, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1303801997, states[0] = -94.108054, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1314941758, states[0] = -94.412832, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1326293038, states[0] = -94.057660, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1337772037, states[0] = -93.916349, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1349083753, states[0] = 15.818980, states[40]= 0.000422
Saving checkpoint... 
Iteration: 1360466568, states[0] = -94.422630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1371916897, states[0] = -94.384894, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1383442030, states[0] = -94.405126, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1394700616, states[0] = -55.167092, states[40]= 0.001479
Saving checkpoint... 
Iteration: 1405806752, states[0] = -94.119237, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1416859047, states[0] = -94.290127, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1427828126, states[0] = -94.202506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1439000888, states[0] = 43.332115, states[40]= 1.177451
Saving checkpoint... 
Iteration: 1450503508, states[0] = 21.765925, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1474333633, states[0] = -94.215346, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1485111704, states[0] = 1.603376, states[40]= 0.005952
Saving checkpoint... 
Iteration: 1496088499, states[0] = 13.634399, states[40]= 0.000738
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.295449
 - CaMKt in component CaMK (millimolar): 0.056749
 - cass in component intracellular_ions (millimolar): 0.000105
 - nai in component intracellular_ions (millimolar): 8.617335
 - nass in component intracellular_ions (millimolar): 8.617540
 - ki in component intracellular_ions (millimolar): 142.153171
 - kss in component intracellular_ions (millimolar): 142.153132
 - cansr in component intracellular_ions (millimolar): 2.886950
 - cajsr in component intracellular_ions (millimolar): 2.838294
 - cai in component intracellular_ions (millimolar): 0.000110
 - m in component INa (dimensionless): 0.003847
 - hf in component INa (dimensionless): 0.869074
 - hs in component INa (dimensionless): 0.869061
 - j in component INa (dimensionless): 0.868970
 - hsp in component INa (dimensionless): 0.705514
 - jp in component INa (dimensionless): 0.868898
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.670160
 - hLp in component INaL (dimensionless): 0.380754
 - a in component Ito (dimensionless): 0.000649
 - iF in component Ito (dimensionless): 0.999855
 - iS in component Ito (dimensionless): 0.546612
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999855
 - iSp in component Ito (dimensionless): 0.607620
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.864243
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999491
 - jca in component ICaL (dimensionless): 0.999927
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.006198
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.450113
 - xs1 in component IKs (dimensionless): 0.343225
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997493
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
23:36:07 (10859): called boinc_finish(0)

</stderr_txt>
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