𝕏

Task 55842095

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_EPI_5000-conf_518_1
Workunit 26517690
Created 3 Jul 2024, 5:07:45 UTC
Sent 3 Jul 2024, 6:36:57 UTC
Report deadline 6 Jul 2024, 6:36:57 UTC
Received 3 Jul 2024, 21:40:06 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227233
Run time 4 hours 27 min 17 sec
CPU time 2 hours 11 min 7 sec
Validate state Valid
Credit 45.96
Device peak FLOPS 3.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 6.31 MB
Peak swap size 32.86 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.20.7</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_EPI_5000-conf_518.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_EPI_5000-conf_518_1_r759213372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Drouin_EPI_5000-conf_518_1_r759213372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.675638
     * GNaL_b in INaL: 0.005782
     * Gto_b in Ito: 0.085467
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032255
     * GKs_b in IKs: 0.001904
     * GK1_b in IK1: 0.162293
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.040806
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034849
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11422825, states[0] = -94.316884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22821269, states[0] = -94.101240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34190266, states[0] = -94.222522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45669369, states[0] = -94.242239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57059975, states[0] = -94.204669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68488799, states[0] = -94.232666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79960875, states[0] = -94.204506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91395571, states[0] = -94.223656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102893911, states[0] = -94.173552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114248750, states[0] = -94.219753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125438321, states[0] = -94.209652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136775526, states[0] = -94.221611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148095860, states[0] = -94.252334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159281591, states[0] = -94.222745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170647440, states[0] = -94.255609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182115933, states[0] = -94.218539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193292767, states[0] = -94.254135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204711989, states[0] = -94.217683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215755358, states[0] = -94.255389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226956906, states[0] = -94.220837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238347295, states[0] = -94.252149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249620305, states[0] = -94.218639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260803829, states[0] = -94.253685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272012522, states[0] = -94.219840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283255963, states[0] = -94.255037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294388905, states[0] = -94.221419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305784504, states[0] = -94.253988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317195697, states[0] = -94.217259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328623554, states[0] = -94.240115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339727239, states[0] = -94.216717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350921725, states[0] = -94.248150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362417837, states[0] = -94.214705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373915928, states[0] = -94.230337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385400487, states[0] = -94.184371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396817126, states[0] = -94.221610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408173068, states[0] = -94.254958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419412061, states[0] = -94.219901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430647890, states[0] = -94.254390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441948300, states[0] = -94.219155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453147846, states[0] = -94.254171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464411371, states[0] = -94.219476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475733943, states[0] = -94.253764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486936952, states[0] = -94.218883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498398778, states[0] = -94.247708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509807111, states[0] = -94.214282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521163436, states[0] = -94.236801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532503723, states[0] = 13.295701, states[40]= 1.117761
Saving checkpoint... 
Iteration: 543759596, states[0] = -94.233298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554906495, states[0] = -94.212943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566385469, states[0] = -94.229309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577863995, states[0] = -94.142913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607794769, states[0] = -94.001765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619163847, states[0] = -94.222246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630442535, states[0] = -94.211409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641614738, states[0] = -94.223032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652962344, states[0] = -94.220902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664543730, states[0] = -94.215712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675946220, states[0] = -94.243976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687145580, states[0] = -94.214259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698470549, states[0] = -94.242723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709750383, states[0] = -94.212907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721178789, states[0] = -94.234318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732389153, states[0] = -94.211374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743590665, states[0] = -94.237379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754619966, states[0] = -94.213901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765830520, states[0] = -94.247919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777135889, states[0] = -94.213497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788602487, states[0] = -94.236487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799847079, states[0] = -94.211097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801441529, states[0] = -94.225531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826459900, states[0] = -94.224818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852875901, states[0] = -94.154997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879126007, states[0] = -94.220497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905811228, states[0] = -94.247297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926799004, states[0] = -94.216787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941098781, states[0] = -94.235156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953876054, states[0] = -94.225823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964977969, states[0] = -94.208379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976081993, states[0] = -94.235470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987470237, states[0] = -94.208222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998330080, states[0] = -94.245690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009361753, states[0] = -94.214959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020004858, states[0] = 14.364431, states[40]= 0.728236
Saving checkpoint... 
Iteration: 1031114274, states[0] = -94.233690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042105166, states[0] = -94.211290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053170976, states[0] = -94.248721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064619060, states[0] = -94.210907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075655361, states[0] = -94.248314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086796157, states[0] = -94.215283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097873741, states[0] = -94.150086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108623293, states[0] = -94.232599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119405084, states[0] = -94.213227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130472507, states[0] = -94.220477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141354309, states[0] = -94.224626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152115912, states[0] = -94.210097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163150870, states[0] = -94.247386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174022063, states[0] = -94.219938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184856499, states[0] = -94.207282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195636757, states[0] = -94.246705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206436013, states[0] = -94.221757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217270122, states[0] = -94.207790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228727911, states[0] = -94.227715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239758462, states[0] = -94.207688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251031977, states[0] = -94.234816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262530905, states[0] = 26.266939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273928439, states[0] = -94.221298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285125573, states[0] = -17.692953, states[40]= 0.000240
Saving checkpoint... 
Iteration: 1296641415, states[0] = -94.216134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307847881, states[0] = -94.112363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319404753, states[0] = -94.211293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330877538, states[0] = -94.240557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342365391, states[0] = -94.205671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353626052, states[0] = -94.230124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364952180, states[0] = -94.204707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376199310, states[0] = -94.227260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387361759, states[0] = -94.205268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398532757, states[0] = -94.233357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409531917, states[0] = -94.208643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420502343, states[0] = -94.227485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431699116, states[0] = -94.213689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443196671, states[0] = -94.244954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466809786, states[0] = -94.211373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477655010, states[0] = -50.517930, states[40]= 0.000084
Saving checkpoint... 
Iteration: 1488495540, states[0] = -94.234032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499620370, states[0] = -94.206678, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.078994
 - CaMKt in component CaMK (millimolar): 0.001691
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.100208
 - nass in component intracellular_ions (millimolar): 7.100344
 - ki in component intracellular_ions (millimolar): 144.598921
 - kss in component intracellular_ions (millimolar): 144.598908
 - cansr in component intracellular_ions (millimolar): 2.388650
 - cajsr in component intracellular_ions (millimolar): 2.389004
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003932
 - hf in component INa (dimensionless): 0.864972
 - hs in component INa (dimensionless): 0.864973
 - j in component INa (dimensionless): 0.864974
 - hsp in component INa (dimensionless): 0.698148
 - jp in component INa (dimensionless): 0.864975
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706945
 - hLp in component INaL (dimensionless): 0.513125
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.999849
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999849
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998814
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005254
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001769
 - xs1 in component IKs (dimensionless): 0.023356
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997545
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:37:30 (10852): called boinc_finish(0)

</stderr_txt>
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